John C. VanRens

536 citations

14 papers · 335 · h-index 12

Impact in

Organic Chemistry top 10%
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Quinazolinone synthesis and applications
- Multicomponent Synthesis of Heterocycles
- Click Chemistry and Applications
Oncology
- Cytokine Signaling Pathways and Interactions

Papers in

Organic Chemistry 11
- Synthesis and biological activity 9
- Quinazolinone synthesis and applications 4
- Synthesis and Characterization of Heterocyclic Compounds 3
Oncology 10
- Cytokine Signaling Pathways and Interactions 8

Co-authors: Biswanath De (14 shared papers)Lily C. Hsieh (12 shared papers)Michael J. Janusz (12 shared papers)Matthew J. Laufersweiler (13 shared papers)Todd A. Brugel (12 shared papers)Michael P. Clark (9 shared papers)Adam Gołȩbiowski (12 shared papers)M. Sabat (12 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (13 papers)Heterocycles (1 paper)
Partner nations: United States

In The Last Decade

John C. VanRens

14 papers receiving 319 citations

Peers

Countries citing papers authored by John C. VanRens

Since Specialization

Citations

This map shows the geographic impact of John C. VanRens's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John C. VanRens with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John C. VanRens more than expected).

Fields of papers citing papers by John C. VanRens

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John C. VanRens. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John C. VanRens. The network helps show where John C. VanRens may publish in the future.

Co-authors

The 25 scholars most cited alongside John C. VanRens, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John C. VanRens Line = papers co-authored together John C. VanRens links everyone, so they are left out of the graph.

All Works

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14 of 14 papers shown

#	Work
1	The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck) Bioorganic & Medicinal Chemistry Letters ·M. Sabat, John C. VanRens, Matthew J. Laufersweiler, Todd A. Brugel, Jennifer Maier, Adam Gołȩbiowski, Biswanath De, Vijayasurian Easwaran, Lily C. Hsieh, Richard L. Walter, Marlene Mekel, A.G. Evdokimov, Michael J. Janusz	2006	57
2	Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3) Bioorganic & Medicinal Chemistry Letters ·Michael P. Clark, Kelly M. George, Roger G. Bookland, Jack Chen, Steven K. Laughlin, Kumar Thakur, Wenlin Lee, Jan R. Davis, Ed J. Cabrera, Todd A. Brugel, John C. VanRens, Matthew J. Laufersweiler, Jennifer A. Maier, M. Sabat, Adam Gołȩbiowski, Vijay Easwaran, Mark E. Webster, Biswanath De, George Zhang	2006	50
3	The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-α) production Bioorganic & Medicinal Chemistry Letters ·Steven K. Laughlin, Michael P. Clark, Jane F. Djung, Adam Gołȩbiowski, Todd A. Brugel, M. Sabat, Roger G. Bookland, Matthew J. Laufersweiler, John C. VanRens, Jennifer A. Townes, Biswanath De, Lily C. Hsieh, Susan C. Xu, Richard L. Walter, Marlene Mekel, Michael J. Janusz	2005	49
4	The development of new triazole based inhibitors of tumor necrosis factor-α (TNF-α) production Bioorganic & Medicinal Chemistry Letters ·Joshua S. Tullis, John C. VanRens, Michael G. Natchus, Michael P. Clark, Biswanath De, Lily C. Hsieh, Michael J. Janusz	2003	44
5	The development of monocyclic pyrazolone based cytokine synthesis inhibitors Bioorganic & Medicinal Chemistry Letters ·Adam Gołȩbiowski, Jennifer A. Townes, Matthew J. Laufersweiler, Todd A. Brugel, Michael P. Clark, Cynthia M. Clark, Jane F. Djung, Steven K. Laughlin, M. Sabat, Roger G. Bookland, John C. VanRens, Biswanath De, Lily C. Hsieh, Michael J. Janusz, Richard L. Walter, Mark E. Webster, Marlene Mekel	2005	20
6	The development of novel 1,2-dihydro-pyrimido[4,5-c]pyridazine based inhibitors of lymphocyte specific kinase (Lck) Bioorganic & Medicinal Chemistry Letters ·M. Sabat, John C. VanRens, Todd A. Brugel, Jennifer Maier, Matthew J. Laufersweiler, Adam Gołȩbiowski, Biswanath De, Vijayasurian Easwaran, Lily C. Hsieh, Jeff Rosegen, Steve Berberich, Eric G. Suchanek, Michael J. Janusz	2006	18
7	The development of new carboxylic acid-based MMP inhibitors derived from a cyclohexylglycine scaffold Bioorganic & Medicinal Chemistry Letters ·Joshua S. Tullis, Matthew J. Laufersweiler, John C. VanRens, Michael G. Natchus, Roger G. Bookland, Neil G. Almstead, Stanisław Pikul, Biswanath De, Lily C. Hsieh, Michael J. Janusz, Todd M. Branch, Sean Peng, Yingkun Y. Jin, Tomáš Hudlický, Kofi A. Oppong	2001	17
8	The development of novel inhibitors of tumor necrosis factor-α (TNF-α) production based on substituted [5,5]-bicyclic pyrazolones Bioorganic & Medicinal Chemistry Letters ·Matthew J. Laufersweiler, Todd A. Brugel, Michael P. Clark, Adam Gołȩbiowski, Roger G. Bookland, Steven K. Laughlin, M. Sabat, Jennifer A. Townes, John C. VanRens, Biswanath De, Lily C. Hsieh, S.A. Heitmeyer, Karen Juergens, Kimberly K. Brown, Marlene Mekel, Richard L. Walter, Michael J. Janusz	2004	17
9	The development of new bicyclic pyrazole-based cytokine synthesis inhibitors Bioorganic & Medicinal Chemistry Letters ·Jennifer A. Townes, Adam Gołȩbiowski, Michael P. Clark, Matthew J. Laufersweiler, Todd A. Brugel, M. Sabat, Roger G. Bookland, Steve K. Laughlin, John C. VanRens, Biswanath De, Lily C. Hsieh, Susan C. Xu, Michael J. Janusz, Richard L. Walter	2004	17
10	Development of N-2,4-pyrimidine-N-phenyl-N′-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-α) synthesis. Part 1 Bioorganic & Medicinal Chemistry Letters ·Todd A. Brugel, Jennifer A. Maier, Michael P. Clark, M. Sabat, Adam Gołȩbiowski, Roger G. Bookland, Matthew J. Laufersweiler, Steven K. Laughlin, John C. VanRens, Biswanath De, Lily C. Hsieh, Marlene Mekel, Michael J. Janusz	2006	15
11	Development of N-4,6-pyrimidine-N-alkyl-N′-phenyl ureas as orally active inhibitors of lymphocyte specific tyrosine kinase Bioorganic & Medicinal Chemistry Letters ·Jennifer A. Maier, Todd A. Brugel, M. Sabat, Adam Gołȩbiowski, Matthew J. Laufersweiler, John C. VanRens, Corey R. Hopkins, Biswanath De, Lily C. Hsieh, Kimberly K. Brown, Vijayasurian Easwaran, Michael J. Janusz	2006	12
12	The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-α production Bioorganic & Medicinal Chemistry Letters ·M. Sabat, John C. VanRens, Michael P. Clark, Todd A. Brugel, Jennifer Maier, Roger G. Bookland, Matthew J. Laufersweiler, Steven K. Laughlin, Adam Gołȩbiowski, Biswanath De, Lily C. Hsieh, Richard L. Walter, Marlene Mekel, Michael J. Janusz	2006	11
13	Development of N-2,4-pyrimidine-N-phenyl-N′-alkyl ureas as orally active inhibitors of tumor necrosis factor alpha (TNF-α) synthesis. Part 2 Bioorganic & Medicinal Chemistry Letters ·Jennifer A. Maier, Todd A. Brugel, Michael P. Clark, M. Sabat, Adam Gołȩbiowski, Roger G. Bookland, Matthew J. Laufersweiler, Steven K. Laughlin, John C. VanRens, Biswanath De, Lily C. Hsieh, Kimberly K. Brown, Karen Juergens, Richard L. Walter, Michael J. Janusz	2006	7
14	Synthesis of Novel Pyrimido[4,5-c]pyridazines and 1,2-Dihydro-3a,7,9,9b-Tetraaza-cyclopenta[a]naphthalen-3-ones as Potent Inhibitors of Lymphocyte Specific Kinase (LCK) Heterocycles ·M. Sabat, John C. VanRens, Todd A. Brugel, Jennifer Maier, Matthew J. Laufersweiler, Adam Gołȩbiowski, Steve Berberich, Biswanath De	2006	1

About John C. VanRens

John C. VanRens is a scholar working on Organic Chemistry, Oncology, Molecular Biology, Pharmacology and Cancer Research, having authored 14 papers that have together received 335 indexed citations. Recurring topics across this work include Synthesis and biological activity (9 papers), Cytokine Signaling Pathways and Interactions (8 papers), Quinazolinone synthesis and applications (4 papers), Synthesis and Characterization of Heterocyclic Compounds (3 papers), Melanoma and MAPK Pathways (2 papers), Pharmacological Effects of Natural Compounds (2 papers), Medicinal Plant Pharmacodynamics Research (1 paper) and Signaling Pathways in Disease (1 paper). The work is most often cited by research in Organic Chemistry (252 citations), Oncology (76 citations), Computational Theory and Mathematics (35 citations), Toxicology (6 citations) and Molecular Biology (110 citations). John C. VanRens has collaborated with scholars based in United States. Frequent co-authors include Biswanath De, Lily C. Hsieh, Michael J. Janusz, Matthew J. Laufersweiler, Todd A. Brugel, Michael P. Clark, Adam Gołȩbiowski, M. Sabat, Roger G. Bookland and Marlene Mekel. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters and Heterocycles.

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John C. VanRens

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