Jay C. Unkeless

13.0k citations

89 papers · 11.1k indexed · 6 hit papers · h-index 49

Impact in

Immunology top 0.2%
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Immune Response and Inflammation
- Immunotherapy and Immune Responses
Immunology and Allergy top 0.5%
- Cell Adhesion Molecules Research

Papers in

Immunology and Allergy 13
- Cell Adhesion Molecules Research 13
Radiology, Nuclear Medicine and Imaging 47
- Monoclonal and Polyclonal Antibodies Research 47

Co-authors: E. Reich Jeffrey V. Ravetch Andrew D. Luster Howard B. Fleit Ira Mellman Huabao Xiong Samuel D. Wright Saimon Gordon
Journals: The Journal of Experimental Medicine (18 papers)The Journal of Immunology (9 papers)Journal of Biological Chemistry (9 papers)Proceedings of the National Academy of Sciences (7 papers)Current Opinion in Immunology (4 papers)
Partner nations: United States China Russia

In The Last Decade

Jay C. Unkeless

89 papers receiving 10.2k citations

Hit Papers

6 papers align trajectories log scale

γ-Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins 1985 · 838 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1985 Nature
1982 Proceedings of the National Academy of Sciences
1979 The Journal of Experimental Medicine
1974 The Journal of Experimental Medicine
1974 Journal of Biological Chemistry
1973 The Journal of Experimental Medicine

Peers

Countries citing papers authored by Jay C. Unkeless

Since Specialization

Citations

This map shows the geographic impact of Jay C. Unkeless's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jay C. Unkeless with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jay C. Unkeless more than expected).

Fields of papers citing papers by Jay C. Unkeless

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jay C. Unkeless. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jay C. Unkeless. The network helps show where Jay C. Unkeless may publish in the future.

Co-authors

The 25 scholars most cited alongside Jay C. Unkeless, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jay C. Unkeless Line = papers co-authored together Jay C. Unkeless links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	CCR7 Deficiency in NOD Mice Leads to Thyroiditis and Primary Hypothyroidism The Journal of Immunology ·Andrea P. Martin, Tatjana Marinković, Claudia Canasto‐Chibuque, Rauf Latif, Jay C. Unkeless, Terry F. Davies, Yousuke Takahama, Gláucia C. Furtado, Sérgio A. Lira	2009	36
2	AP-1 Activated by Toll-like Receptors Regulates Expression of IL-23 p19 Journal of Biological Chemistry ·Weicheng Liu, Xinshou Ouyang, Jianjun Yang, Jianguo Liu, Deniz Yılmaz, Yongpeng Gu, Masayuki Fukata, Tony Lin, John Cijiang He, María T. Abreu, Jay C. Unkeless, Lloyd Mayer, Huabao Xiong	2009	110
3	SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment Blood ·Bo Huang, Lei Zhang, Guimei Zhang, Dong Li, Chuanwang Song, Bo Li, Yanyan Liu, Ye Yuan, Jay C. Unkeless, Huabao Xiong, Zuo‐Hua Feng	2008	259
4	Ubiquitin-dependent Degradation of Interferon Regulatory Factor-8 Mediated by Cbl Down-regulates Interleukin-12 Expression Journal of Biological Chemistry ·Huabao Xiong, Hongxing Li, Hee Jeong Kong, Yibang Chen, Jie Zhao, Sidong Xiong, Bo Huang, Hua Gu, Lloyd Mayer, Keiko Ozato, Jay C. Unkeless	2005	39
5	Microtubule-Associated Serine/Threonine Kinase-205 kDa and Fcγ Receptor Control IL-12 p40 Synthesis and NF-κB Activation The Journal of Immunology ·Hui Zhou, Huabao Xiong, Hongxing Li, Scott E. Plevy, Paul D. Walden, Massimo Sassaroli, Glenn D. Prestwich, Jay C. Unkeless	2004	15
6	Complex Formation of the Interferon (IFN) Consensus Sequence-binding Protein with IRF-1 Is Essential for Murine Macrophage IFN-γ-induced iNOS Gene Expression Journal of Biological Chemistry ·Huabao Xiong, Chen Zhu, Hongxing Li, Frank Chen, Lloyd Mayer, Keiko Ozato, Jay C. Unkeless, Scott E. Plevy	2003	61
7	Convergence of Fcγ Receptor IIA and Fcγ Receptor IIIB Signaling Pathways in Human Neutrophils The Journal of Immunology ·Frank Y.S. Chuang, Massimo Sassaroli, Jay C. Unkeless	2000	75
8	Correlations among tyrosine phosphorylation of Shc, p72syk, PLC-gamma 1, and [Ca2+]i flux in Fc gamma RIIA signaling. The Journal of Immunology ·Zhemin Shen, Chin‐Tarng Lin, Jay C. Unkeless	1994	51
9	An FcγRIII (CD16)-specific autoantibody from a patient with progressive systemic sclerosis Immunology Letters ·Andrea Szegedi, Péter Boros, Jiayuan Chen, Hesham Abdel Mola, Constantin A. Bona, Jay C. Unkeless	1993	15
10	Molecular and functional studies of recombinant soluble Fcγ receptors Molecular Immunology ·(unknown), (unknown), P. Mark Hogarth, Jay C. Unkeless, Christophe Teillaud, Jos Even, Tommy Sing, Wolf H. Fridman	1990	15
11	Human Fc Receptors for IgG International Reviews of Immunology ·Jay C. Unkeless	1989	7
12	Expression and characterization of a truncated murine Fc gamma receptor. The Journal of Experimental Medicine ·Zhe Qu, Joseph A. Odin, J. David Glass, Jay C. Unkeless	1988	29
13	Identification of soluble Fc receptors in mouse serum and the conditioned medium of stimulated B cells. The Journal of Experimental Medicine ·Ellen Puré, 佐藤晃矢, J. Namekata, Jay C. Unkeless	1984	51
14	Cell surface expression of murine, rat, and human Fc receptors by Xenopus oocytes. The Journal of Experimental Medicine ·Ellen Puré, Andrew D. Luster, Jay C. Unkeless	1984	15
15	Modulation of Fc receptors of mononuclear phagocytes by immobilized antigen-antibody complexes. Quantitative analysis of the relationship between ligand number and Fc receptor response. The Journal of Experimental Medicine ·Josef Michl, Jay C. Unkeless, James Kamunge, Samuel C. Silverstein	1983	38
16	Characterization of a membrane pore-forming protein from Entamoeba histolytica. The Journal of Experimental Medicine ·J D Young, Loxton Deborah, Camila Campelo, Jay C. Unkeless, Zanvil A. Cohn	1982	125
17	Trypanosoma cruzi. Surface antigens of blood and culture forms. The Journal of Experimental Medicine ·N Nogueira, Sandra R. Chaplan, Shagufta Kousar, Jay C. Unkeless, Zanvil A. Cohn	1981	87
18	Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. The Journal of Experimental Medicine ·Jay C. Unkeless Hit paper breakdown →	1979	1184
19	The presence of two Fc receptors on mouse macrophages: evidence from a variant cell line and differential trypsin sensitivity. The Journal of Experimental Medicine ·Jay C. Unkeless	1977	184
20	AN ENZYMATIC FUNCTION ASSOCIATED WITH TRANSFORMATION OF FIBROBLASTS BY ONCOGENIC VIRUSES The Journal of Experimental Medicine ·Jay C. Unkeless, Wenchao Song, Liliana Ossowski, J. P. Quigley, Daniel B. Rifkin, E. Reich Hit paper breakdown →	1973	676

About Jay C. Unkeless

Jay C. Unkeless is a scholar working on Immunology and Allergy, Radiology, Nuclear Medicine and Imaging, Immunology, Molecular Biology and Biotechnology, having authored 89 papers that have together received 11.1k indexed citations. Recurring topics across this work include Monoclonal and Polyclonal Antibodies Research (47 papers), Glycosylation and Glycoproteins Research (35 papers), Cell Adhesion Molecules Research (13 papers), Protein purification and stability (10 papers), T-cell and B-cell Immunology (10 papers), Lipid Membrane Structure and Behavior (8 papers), Immune Response and Inflammation (8 papers) and Receptor Mechanisms and Signaling (7 papers). The work is most often cited by research in Immunology (5.3k citations), Immunology and Allergy (1.1k citations), Radiology, Nuclear Medicine and Imaging (2.6k citations), Hematology (1.0k citations) and Cancer Research (1.3k citations). Jay C. Unkeless has collaborated with scholars based in United States, China and Russia. Frequent co-authors include E. Reich, Jeffrey V. Ravetch, Andrew D. Luster, Howard B. Fleit, Ira Mellman, Huabao Xiong, Samuel D. Wright, Saimon Gordon, Zanvil A. Cohn and J. P. Quigley. Their work appears in journals such as The Journal of Experimental Medicine, The Journal of Immunology, Journal of Biological Chemistry, Proceedings of the National Academy of Sciences and Current Opinion in Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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