Jason Thresher

1.4k citations

19 papers · 892 indexed · h-index 12

Impact in

Molecular Medicine top 0.5%
- Antibiotic Resistance in Bacteria
Applied Microbiology and Biotechnology top 1%
- Antibiotic Use and Resistance

Papers in

Molecular Medicine 8
- Antibiotic Resistance in Bacteria 8
Infectious Diseases 5

Co-authors: Ning Gao David E. Ehmann Rong-Fang Gu Stephania Livchak Adam B. Shapiro Sushmita D. Lahiri Grant K. Walkup Tiffany Palmer
Journals: SLAS DISCOVERY (5 papers)Antimicrobial Agents and Chemotherapy (3 papers)Journal of Biological Chemistry (2 papers)Analytical Biochemistry (2 papers)ACS Medicinal Chemistry Letters (1 paper)
Partner nations: United States United Kingdom South Korea

In The Last Decade

Jason Thresher

19 papers receiving 855 citations

Peers

Countries citing papers authored by Jason Thresher

Since Specialization

Citations

This map shows the geographic impact of Jason Thresher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jason Thresher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jason Thresher more than expected).

Fields of papers citing papers by Jason Thresher

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jason Thresher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jason Thresher. The network helps show where Jason Thresher may publish in the future.

Co-authors

The 25 scholars most cited alongside Jason Thresher, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jason Thresher Line = papers co-authored together Jason Thresher links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	Inhibition of Neisseria gonorrhoeae Type II Topoisomerases by the Novel Spiropyrimidinetrione AZD0914 Journal of Biological Chemistry ·Günther Kern, Tiffany Palmer, David E. Ehmann, Adam B. Shapiro, Beth Andrews, Gregory S. Basarab, P. Doig, Jun Fan, Ning Gao, Scott D. Mills, John P. Mueller, Shubha Sriram, Jason Thresher, Grant K. Walkup	2015	39
2	Molecular Mechanisms of Sulbactam Antibacterial Activity and Resistance Determinants in Acinetobacter baumannii Antimicrobial Agents and Chemotherapy ·William F. Penwell, Adam B. Shapiro, R.A. Giacobbe, Rong-Fang Gu, Ning Gao, Jason Thresher, Robert E. McLaughlin, Michael D. Huband, Boudewijn L DeJonge, David E. Ehmann, Alita A. Miller	2015	183
3	Selection and molecular characterization of ceftazidime/avibactam-resistant mutants in Pseudomonas aeruginosa strains containing derepressed AmpC Journal of Antimicrobial Chemotherapy ·Sushmita D. Lahiri, Grant K. Walkup, James Whiteaker, Tiffany Palmer, Kathy McCormack, M. Angela Tanudra, Tory J. Nash, Jason Thresher, Michele Johnstone, Laurie Hajec, Stephania Livchak, Robert E. McLaughlin, Richard A. Alm	2015	106
4	Target-Based Resistance in Pseudomonas aeruginosa and Escherichia coli to NBTI 5463, a Novel Bacterial Type II Topoisomerase Inhibitor Antimicrobial Agents and Chemotherapy ·Asha S. Nayar, Thomas J. Dougherty, Folkert Reck, Jason Thresher, Ning Gao, Adam B. Shapiro, David E. Ehmann	2014	21
5	Overexpression of Pseudomonas aeruginosa LpxC with its inhibitors in an acrB-deficient Escherichia coli strain Protein Expression and Purification ·Ning Gao, Sarah M. McLeod, Laurel Hajec, N.B. Olivier, Sushmita D. Lahiri, D. Bryan Prince, Jason Thresher, Philip L. Ross, James Whiteaker, P. Doig, Amanda Haixi Li, Pamela Hill, Mark Cornebise, Folkert Reck, Michael Hale	2014	6
6	Fluorescence anisotropy-based measurement of Pseudomonas aeruginosa penicillin-binding protein 2 transpeptidase inhibitor acylation rate constants Analytical Biochemistry ·Adam B. Shapiro, Ning Gao, Rong-Fang Gu, Jason Thresher	2014	13
7	Synthesis, Structure, and SAR of Tetrahydropyran-Based LpxC Inhibitors ACS Medicinal Chemistry Letters ·Kerry E. Murphy-Benenato, N.B. Olivier, Allison L. Choy, Philip L. Ross, M.D. Miller, Jason Thresher, Ning Gao, Michael Hale	2014	21
8	Quantitative investigation of the affinity of human respiratory syncytial virus phosphoprotein C-terminus binding to nucleocapsid protein Virology Journal ·Adam B. Shapiro, Ning Gao, Nichole O’Connell, Jun Hu, Jason Thresher, Rong-Fang Gu, R. Overman, Ian M. Hardern, Graham Sproat	2014	10
9	Discovery of ATP-Competitive Inhibitors of tRNAIle Lysidine Synthetase (TilS) by High-Throughput Screening SLAS DISCOVERY ·Adam B. Shapiro, Helen Plant, Jarrod Walsh, Mark Sylvester, Jun Hu, Ning Gao, Stephania Livchak, Sharon Tentarelli, Jason Thresher	2014	5
10	Mechanism of Action for Respiratory Syncytial Virus Inhibitor RSV604 Antimicrobial Agents and Chemotherapy ·Sreerupa Challa, Andrew D. Scott, Olga Yuzhakov, Ying Zhou, Choi Lai Tiong-Yip, Ning Gao, Jason Thresher, Qin Yu	2014	48
11	Exploring the UDP pocket of LpxC through amino acid analogs Bioorganic & Medicinal Chemistry Letters ·Michael Hale, Pamela Hill, Sushmita D. Lahiri, M.D. Miller, Philip L. Ross, Richard A. Alm, Ning Gao, Amy Kutschke, Michele Johnstone, Bryan Prince, Jason Thresher, Wei Yang	2013	20
12	Kinetics of Avibactam Inhibition against Class A, C, and D β-Lactamases Journal of Biological Chemistry ·David E. Ehmann, Haris Jahić, Philip L. Ross, Rong-Fang Gu, Jun Hu, Thomas F. Durand-Réville, Sushmita D. Lahiri, Jason Thresher, Stephania Livchak, Ning Gao, Tiffany Palmer, Grant K. Walkup, Stewart L. Fisher	2013	301
13	Continuous fluorescence anisotropy-based assay of BOCILLIN FL penicillin reaction with penicillin binding protein 3 Analytical Biochemistry ·Adam B. Shapiro, Rong-Fang Gu, Ning Gao, Stephania Livchak, Jason Thresher	2013	27
14	Selective Inhibitors of Bacterial t-RNA-(N¹G37) Methyltransferase (TrmD) That Demonstrate Novel Ordering of the Lid Domain Journal of Medicinal Chemistry ·Pamela Hill, Ayome Abibi, Robert Albert, Beth Andrews, Moriah M. Gagnon, Ning Gao, Tyler Grebe, Laurel Hajec, Jian Huang, Stephania Livchak, Sushmita D. Lahiri, David C. McKinney, Jason Thresher, Hongming Wang, N.B. Olivier, Ed T. Buurman	2013	43
15	The kinetic mechanism of S. pneumoniae DNA ligase and inhibition by adenosine-based antibacterial compounds Biochemical Pharmacology ·Haris Jahić, Ce Feng Liu, Jason Thresher, Stephania Livchak, Hongming Wang, David E. Ehmann	2012	7
16	A High-Throughput–Compatible Fluorescence Anisotropy-Based Assay for Competitive Inhibitors of Escherichia coli UDP-N-Acetylglucosamine Acyltransferase (LpxA) SLAS DISCOVERY ·Adam B. Shapiro, Philip L. Ross, Ning Gao, Stephania Livchak, Günther Kern, Wei Yang, Beth Andrews, Jason Thresher	2012	8
17	A High-Throughput Absorbance-Based Assay for Methionine Produced by Methionine Aminopeptidase Using S-Adenosyl-L-Methionine Synthetase SLAS DISCOVERY ·Adam B. Shapiro, Ning Gao, Jason Thresher, Grant K. Walkup, James Whiteaker	2011	5
18	A Homogeneous, High-Throughput-Compatible, Fluorescence Intensity–Based Assay for UDP-N-Acetylenolpyruvylglucosamine Reductase (MurB) with Nanomolar Product Detection SLAS DISCOVERY ·Adam B. Shapiro, Stephania Livchak, Ning Gao, James Whiteaker, Jason Thresher, Haris Jahić, Jian Huang, Rong-Fang Gu	2011	5
19	A Homogeneous, High-Throughput Fluorescence Anisotropy-Based DNA Supercoiling Assay SLAS DISCOVERY ·Adam B. Shapiro, Haris Jahić, Swati Prasad, David E. Ehmann, Jason Thresher, Ning Gao, Laurel Hajec	2010	24

About Jason Thresher

Jason Thresher is a scholar working on Molecular Medicine, Infectious Diseases, Pharmacology, Molecular Biology and Microbiology, having authored 19 papers that have together received 892 indexed citations. Recurring topics across this work include Antibiotic Resistance in Bacteria (8 papers), Cancer therapeutics and mechanisms (4 papers), Bacterial Genetics and Biotechnology (4 papers), Antibiotics Pharmacokinetics and Efficacy (3 papers), Glycosylation and Glycoproteins Research (2 papers), RNA and protein synthesis mechanisms (2 papers), RNA modifications and cancer (2 papers) and Enzyme Structure and Function (2 papers). The work is most often cited by research in Molecular Medicine (656 citations), Applied Microbiology and Biotechnology (125 citations), Pharmacology (406 citations), Endocrinology (105 citations) and Pollution (92 citations). Jason Thresher has collaborated with scholars based in United States, United Kingdom and South Korea. Frequent co-authors include Ning Gao, David E. Ehmann, Rong-Fang Gu, Stephania Livchak, Adam B. Shapiro, Sushmita D. Lahiri, Grant K. Walkup, Tiffany Palmer, Philip L. Ross and Haris Jahić. Their work appears in journals such as SLAS DISCOVERY, Antimicrobial Agents and Chemotherapy, Journal of Biological Chemistry, Analytical Biochemistry and ACS Medicinal Chemistry Letters.

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