Janusz Puc

7.3k total citations · 1 hit paper
21 papers, 5.7k citations indexed

About

Janusz Puc is a scholar working on Oncology, Molecular Biology and Immunology. According to data from OpenAlex, Janusz Puc has authored 21 papers receiving a total of 5.7k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Oncology, 11 papers in Molecular Biology and 4 papers in Immunology. Recurrent topics in Janusz Puc's work include CAR-T cell therapy research (9 papers), PI3K/AKT/mTOR signaling in cancer (7 papers) and DNA Repair Mechanisms (4 papers). Janusz Puc is often cited by papers focused on CAR-T cell therapy research (9 papers), PI3K/AKT/mTOR signaling in cancer (7 papers) and DNA Repair Mechanisms (4 papers). Janusz Puc collaborates with scholars based in United States, Poland and Australia. Janusz Puc's co-authors include Ramon Parsons, Katrina Podsypanina, Hanina Hibshoosh, Steven I. Wang, Ben Tycko, W. Richard McCombie, Beppino C. Giovanella, Linda Rodgers, Sandra H. Bigner and Michael Wigler and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Janusz Puc

20 papers receiving 5.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

1997 3.9k citations Jing Li, Danny Liaw et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Janusz Puc United States	11	4.7k	1.4k	1.0k	749	685	21	5.7k
Danny Liaw United States	9	4.5k 1.0×	1.2k 0.9×	989 1.0×	884 1.2×	635 0.9×	16	5.8k
Katrina Podsypanina United States	23	5.7k 1.2×	2.1k 1.5×	1.3k 1.3×	784 1.0×	910 1.3×	36	7.4k
Ralf Lesche Germany	31	3.9k 0.8×	1.1k 0.8×	1.1k 1.0×	504 0.7×	605 0.9×	63	5.1k
Steven I. Wang United States	7	5.6k 1.2×	1.5k 1.1×	1.2k 1.1×	1.1k 1.5×	746 1.1×	8	6.9k
Sandra E. Dunn Canada	43	3.5k 0.7×	1.5k 1.1×	1.1k 1.1×	351 0.5×	391 0.6×	99	5.1k
Sauveur-Michel Maira Switzerland	31	3.5k 0.7×	1.4k 1.0×	778 0.8×	506 0.7×	821 1.2×	42	4.7k
Anna Lasorella United States	43	4.3k 0.9×	1.6k 1.1×	1.6k 1.5×	390 0.5×	464 0.7×	92	6.8k
Svetlana Pack United States	47	3.1k 0.7×	1.5k 1.1×	1.1k 1.0×	690 0.9×	1.4k 2.0×	130	6.5k
Max Chaffanet France	36	2.4k 0.5×	1.5k 1.1×	1.0k 1.0×	382 0.5×	464 0.7×	105	4.4k
Monica Fedele Italy	46	4.5k 1.0×	1.2k 0.9×	2.4k 2.3×	393 0.5×	552 0.8×	129	6.5k

Countries citing papers authored by Janusz Puc

Since Specialization

Citations

This map shows the geographic impact of Janusz Puc's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Janusz Puc with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Janusz Puc more than expected).

Fields of papers citing papers by Janusz Puc

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Janusz Puc. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Janusz Puc. The network helps show where Janusz Puc may publish in the future.

Co-authorship network of co-authors of Janusz Puc

This figure shows the co-authorship network connecting the top 25 collaborators of Janusz Puc. A scholar is included among the top collaborators of Janusz Puc based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Janusz Puc. Janusz Puc is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Josiah, Serene, et al.. (2024). Abstract 4007: AIC100 CAR-T cells targeting ICAM-1 are efficacious against solid tumors in xenograft mouse models of non-small cell lung cancer (NSCLC) and cervical cancer (CC). Cancer Research. 84(6_Supplement). 4007–4007. 1 indexed citations

Srour, Samer A., Victoria Villaflor, Jochen H. Lorch, et al.. (2024). Safety and efficacy of AIC100 chimeric antigen receptor (CAR) T-cell therapy in patients with advanced thyroid cancers: Results from the phase 1 study.. Journal of Clinical Oncology. 42(16_suppl). 6112–6112. 5 indexed citations

Yang, Yanping, Raymond H. Y. Louie, Janusz Puc, et al.. (2023). Chimeric Antigen Receptor T Cell Therapy Targeting Epithelial Cell Adhesion Molecule in Gastric Cancer: Mechanisms of Tumor Resistance. Cancers. 15(23). 5552–5552. 5 indexed citations

Yang, Yanping, Janusz Puc, Yogindra Vedvyas, et al.. (2023). Inducible expression of interleukin-12 augments the efficacy of affinity-tuned chimeric antigen receptors in murine solid tumor models. Nature Communications. 14(1). 2068–2068. 18 indexed citations

Srour, Samer A., Maria E. Cabanillas, Sonal Gupta, et al.. (2023). Safety and early efficacy results of phase 1 study of affinity tuned and trackable AIC100 CAR T cells in ICAM-1 positive relapsed and/or refractory advanced poorly differentiated and anaplastic thyroid cancers.. Journal of Clinical Oncology. 41(16_suppl). 6095–6095. 5 indexed citations

Hofe, Eric von, Yen‐Michael S. Hsu, Thomas J. Fahey, et al.. (2022). Phase I study of AIC100 in relapsed and/or refractory advanced thyroid cancer and anaplastic thyroid cancer.. Journal of Clinical Oncology. 40(16_suppl). 6093–6093. 5 indexed citations

Yang, Yanping, Janusz Puc, Yogindra Vedvyas, et al.. (2021). Bispecific CAR T Cells against EpCAM and Inducible ICAM-1 Overcome Antigen Heterogeneity and Generate Superior Antitumor Responses. Cancer Immunology Research. 9(10). 1158–1174. 45 indexed citations

Yang, Yanping, Janusz Puc, Yogindra Vedvyas, et al.. (2020). Abstract 6598: Eradication of EpCAM expressing solid tumors by low-affinity CAR T cells. Cancer Research. 80(16_Supplement). 6598–6598. 3 indexed citations

Sun, Qing, Xiaohong Liu, Janusz Puc, et al.. (2018). Abstract 982: Pharmacological DNA-PK inhibition induces ATM/p53 dependent premature senescence with immunomodulatory phenotype in irradiated cancer cells. Cancer Research. 78(13_Supplement). 982–982. 2 indexed citations

10.

Puc, Janusz, Aneel K. Aggarwal, & Michael G. Rosenfeld. (2017). Physiological functions of programmed DNA breaks in signal-induced transcription. Nature Reviews Molecular Cell Biology. 18(8). 471–476. 50 indexed citations

11.

Puc, Janusz, Piotr Koźbiał, Wenbo Li, et al.. (2015). Ligand-Dependent Enhancer Activation Regulated by Topoisomerase-I Activity. Cell. 160(3). 367–380. 106 indexed citations

12.

Gupta, Arun, Qin Yang, Raj K. Pandita, et al.. (2009). Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair. Cell Cycle. 8(14). 2198–2210. 94 indexed citations

13.

Zhu, Ping, Wenlai Zhou, Jianxun Wang, et al.. (2007). A Histone H2A Deubiquitinase Complex Coordinating Histone Acetylation and H1 Dissociation in Transcriptional Regulation. Molecular Cell. 27(4). 609–621. 231 indexed citations

14.

Puc, Janusz, et al.. (2006). Analysis of PTEN Mutation in Non‐familial Pheochromocytoma. Annals of the New York Academy of Sciences. 1073(1). 317–331. 5 indexed citations

15.

Puc, Janusz, Megan Keniry, Tej K. Pandita, et al.. (2005). Lack of PTEN sequesters CHK1 and initiates genetic instability. Cancer Cell. 7(2). 193–204. 258 indexed citations

16.

Puc, Janusz & Ramon Parsons. (2005). PTEN Loss Inhibits CHK1 to Cause Double Stranded-DNA Breaks in Cells. Cell Cycle. 4(7). 927–929. 76 indexed citations

17.

Podsypanina, Katrina, Richard Lee, Janusz Puc, et al.. (2001). An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity inPten^+/−mice. Proceedings of the National Academy of Sciences. 98(18). 10320–10325. 494 indexed citations

18.

Puc, Janusz, Paweł Kwiatkowski, Aleksander P. Mazurek, et al.. (1998). Mitochondrial activity after cold preservation of pancreatic islet cells treated with pefloxacin (PFX).. PubMed. 3(1). 38–41. 3 indexed citations

19.

Puc, Janusz, Jing Li, Jeffrey N. Bruce, et al.. (1997). Somatic mutations of PTEN in glioblastoma multiforme.. PubMed. 57(19). 4183–6. 432 indexed citations

20.

Li, Jing, Danny Liaw, Katrina Podsypanina, et al.. (1997). PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer. Science. 275(5308). 1943–1947. 3896 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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