Jan Šarek

1.8k total citations · 1 hit paper
31 papers, 1.5k citations indexed

About

Jan Šarek is a scholar working on Molecular Biology, Toxicology and Cancer Research. According to data from OpenAlex, Jan Šarek has authored 31 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 29 papers in Molecular Biology, 9 papers in Toxicology and 7 papers in Cancer Research. Recurrent topics in Jan Šarek's work include Natural product bioactivities and synthesis (28 papers), Plant biochemistry and biosynthesis (17 papers) and Bioactive Compounds and Antitumor Agents (9 papers). Jan Šarek is often cited by papers focused on Natural product bioactivities and synthesis (28 papers), Plant biochemistry and biosynthesis (17 papers) and Bioactive Compounds and Antitumor Agents (9 papers). Jan Šarek collaborates with scholars based in Czechia, United Kingdom and Poland. Jan Šarek's co-authors include Milan Urban, Marián Hajdúch, Miroslav Kvasnica, Petr Džubák, David Biedermann, Lenka Marková, David Vydra, Jiří Klinot, Gabriela Kořínková and I. Tišlerová and has published in prestigious journals such as Journal of Medicinal Chemistry, Tetrahedron and Natural Product Reports.

In The Last Decade

Jan Šarek

31 papers receiving 1.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Pharmacological activities of natural triterpenoids and their therapeutic implications

2006 584 citations Petr Džubák, Marián Hajdúch et al. Natural Product Reports profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jan Šarek Czechia	18	1.2k	265	228	216	160	31	1.5k
Milan Urban Czechia	23	1.5k 1.3×	366 1.4×	263 1.2×	219 1.0×	175 1.1×	51	1.9k
Fernando J. Reyes‐Zurita Spain	24	902 0.7×	210 0.8×	92 0.4×	154 0.7×	172 1.1×	49	1.3k
Qiuwen Mi United States	23	848 0.7×	224 0.8×	142 0.6×	247 1.1×	81 0.5×	28	1.2k
Benjamin Wiench Germany	21	615 0.5×	171 0.6×	221 1.0×	373 1.7×	179 1.1×	25	1.2k
Mansukh C. Wani United States	12	1.2k 0.9×	182 0.7×	218 1.0×	151 0.7×	61 0.4×	13	1.3k
Ming‐Jaw Don Taiwan	24	688 0.6×	398 1.5×	170 0.7×	262 1.2×	230 1.4×	44	1.4k
Nadine Kretschmer Austria	18	511 0.4×	202 0.8×	322 1.4×	215 1.0×	61 0.4×	51	978
Thaworn Kowithayakorn Japan	23	956 0.8×	135 0.5×	70 0.3×	243 1.1×	188 1.2×	61	1.3k
Jing-Pin Lin Taiwan	18	731 0.6×	113 0.4×	93 0.4×	227 1.1×	155 1.0×	20	1.3k
Takashi Koyano Japan	29	1.3k 1.1×	535 2.0×	145 0.6×	345 1.6×	603 3.8×	84	2.3k

Countries citing papers authored by Jan Šarek

Since Specialization

Citations

This map shows the geographic impact of Jan Šarek's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jan Šarek with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jan Šarek more than expected).

Fields of papers citing papers by Jan Šarek

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jan Šarek. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jan Šarek. The network helps show where Jan Šarek may publish in the future.

Co-authorship network of co-authors of Jan Šarek

This figure shows the co-authorship network connecting the top 25 collaborators of Jan Šarek. A scholar is included among the top collaborators of Jan Šarek based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jan Šarek. Jan Šarek is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Frydrych, Ivo, J. Pokorný, Martin Vlk, et al.. (2022). Triterpenoid pyrazines and pyridines – Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs. European Journal of Medicinal Chemistry. 243. 114777–114777. 13 indexed citations

Pokorný, J., Ivo Frydrych, Barbora Lišková, et al.. (2021). Substituted dienes prepared from betulinic acid – Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters. European Journal of Medicinal Chemistry. 224. 113706–113706. 8 indexed citations

Rárová, Lucie, Miroslav Šlouf, David Šaman, et al.. (2019). Spermine amides of selected triterpenoid acids: dynamic supramolecular system formation influences the cytotoxicity of the drugs. Journal of Materials Chemistry B. 8(3). 484–491. 24 indexed citations

Drašar, Pavel, Petr Džubák, Soňa Gurská, et al.. (2017). Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid. ChemMedChem. 12(5). 390–398. 23 indexed citations

Tichý, Michal, Miroslav Kvasnica, Lucie Rárová, et al.. (2017). Synthesis and antiproliferative properties of new hydrophilic esters of triterpenic acids. European Journal of Medicinal Chemistry. 140. 403–420. 25 indexed citations

Gurská, Soňa, Petr Džubák, Marián Hajdúch, et al.. (2016). Lupane and 18α-oleanane derivatives substituted in the position 2, their cytotoxicity and influence on cancer cells. European Journal of Medicinal Chemistry. 121. 120–131. 21 indexed citations

Kolátorová, Lucie, Jan Šarek, Jana Vítků, & Miroslav Kvasnica. (2016). Synthesis of 3α-deuterated 7α-hydroxy-DHEA and 7-oxo-DHEA and application in LC-MS/MS plasma analysis. Steroids. 112. 88–94. 5 indexed citations

Jašíková, Lucie, Jiřı́ Řehulka, Milan Urban, et al.. (2015). Synthesis of cytotoxic 2,2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cells. European Journal of Medicinal Chemistry. 96. 482–490. 24 indexed citations

Kvasnica, Miroslav, et al.. (2015). Pentacyclic triterpenoids with nitrogen- and sulfur-containing heterocycles: synthesis and medicinal significance. Natural Product Reports. 32(9). 1303–1330. 117 indexed citations

10.

Vlk, Martin, Milan Urban, Tomáš Elbert, & Jan Šarek. (2013). Synthesis of selectively deuterated and tritiated lupane derivatives with cytotoxic activity. Journal of Radioanalytical and Nuclear Chemistry. 298(2). 1149–1157. 9 indexed citations

11.

Urban, Milan, Martin Vlk, Petr Džubák, Marián Hajdúch, & Jan Šarek. (2012). Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid. Bioorganic & Medicinal Chemistry. 20(11). 3666–3674. 64 indexed citations

12.

Kvasnica, Miroslav, et al.. (2008). Reaction of lupane and oleanane triterpenoids with Lawesson's reagent. Tetrahedron. 64(17). 3736–3743. 14 indexed citations

13.

Džubák, Petr, Marián Hajdúch, David Vydra, et al.. (2006). Pharmacological activities of natural triterpenoids and their therapeutic implications. Natural Product Reports. 23(3). 394–394. 584 indexed citations breakdown →

14.

Šarek, Jan, Milan Urban, Jiří Klinot, et al.. (2006). Reactions of Activated Lupane Oxo-Compounds with Diazomethane: An Approach to New Derivatives of Cytotoxic Triterpenes. Synthesis. 2006(23). 3979–3986. 10 indexed citations

15.

Kvasnica, Miroslav, et al.. (2005). Synthesis of phthalates of betulinic acid and betulin with cytotoxic activity. Bioorganic & Medicinal Chemistry. 13(10). 3447–3454. 84 indexed citations

16.

Šarek, Jan, Miroslav Kvasnica, Milan Urban, Jiří Klinot, & Marián Hajdúch. (2005). Correlation of cytotoxic activity of betulinines and their hydroxy analogues. Bioorganic & Medicinal Chemistry Letters. 15(19). 4196–4200. 27 indexed citations

17.

Urban, Milan, Jan Šarek, I. Tišlerová, Petr Džubák, & Marián Hajdúch. (2005). Influence of esterification and modification of A-ring in a group of lupane acids on their cytotoxicity. Bioorganic & Medicinal Chemistry. 13(19). 5527–5535. 45 indexed citations

18.

Biedermann, David, Jan Šarek, Jiří Klinot, Marián Hajdúch, & Petr Džubák. (2005). Fluorination of Betulinines and Other Triterpenoids with DAST.. ChemInform. 36(41). 2 indexed citations

19.

Urban, Milan, Jan Šarek, Jiří Klinot, Gabriela Kořínková, & Marián Hajdúch. (2004). Synthesis of A-Seco Derivatives of Betulinic Acid with Cytotoxic Activity. Journal of Natural Products. 67(7). 1100–1105. 114 indexed citations

20.

Šarek, Jan, Jiří Klinot, Petr Džubák, et al.. (2003). New Lupane Derived Compounds with Pro-Apoptotic Activity in Cancer Cells: Synthesis and Structure−Activity Relationships. Journal of Medicinal Chemistry. 46(25). 5402–5415. 76 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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