James W. Freeman

4.5k total citations · 1 hit paper
92 papers, 3.6k citations indexed

About

James W. Freeman is a scholar working on Molecular Biology, Oncology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, James W. Freeman has authored 92 papers receiving a total of 3.6k indexed citations (citations by other indexed papers that have themselves been cited), including 50 papers in Molecular Biology, 35 papers in Oncology and 12 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in James W. Freeman's work include Pancreatic and Hepatic Oncology Research (19 papers), TGF-β signaling in diseases (14 papers) and RNA modifications and cancer (12 papers). James W. Freeman is often cited by papers focused on Pancreatic and Hepatic Oncology Research (19 papers), TGF-β signaling in diseases (14 papers) and RNA modifications and cancer (12 papers). James W. Freeman collaborates with scholars based in United States, Australia and Switzerland. James W. Freeman's co-authors include Shujie Zhao, Anand B. Karnad, Chen Chen, Kolaparthi Venkatasubbarao, Michael G. Brattain, Sudhakar Ammanamanchi, Shujie Zhao, Harris Busch, William E. Strodel and Carol Swiderski and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Clinical Oncology and Annals of Internal Medicine.

In The Last Decade

James W. Freeman

87 papers receiving 3.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The biology and role of CD44 in cancer progression: therapeutic implications

2018 938 citations Shujie Zhao, Anand B. Karnad et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
James W. Freeman United States	34	2.2k	1.3k	734	374	331	92	3.6k
Guojun Wu China	38	2.5k 1.1×	1.2k 0.9×	761 1.0×	336 0.9×	167 0.5×	102	4.1k
M. Radhakrishna Pillai India	37	2.0k 0.9×	914 0.7×	719 1.0×	354 0.9×	126 0.4×	138	3.8k
Françis Belloc France	32	1.6k 0.8×	713 0.5×	350 0.5×	485 1.3×	168 0.5×	118	3.8k
M. Iqbal Parker South Africa	37	2.0k 0.9×	1.0k 0.8×	576 0.8×	495 1.3×	218 0.7×	105	3.8k
Yasuo Takano Japan	29	1.6k 0.7×	627 0.5×	448 0.6×	370 1.0×	272 0.8×	76	2.6k
Jean Rosenbaum France	45	2.0k 0.9×	923 0.7×	772 1.1×	369 1.0×	571 1.7×	150	5.3k
Ian C. Paterson United Kingdom	35	1.7k 0.8×	865 0.7×	497 0.7×	256 0.7×	222 0.7×	164	3.6k
Nathalie Théret France	37	1.4k 0.7×	755 0.6×	649 0.9×	550 1.5×	241 0.7×	87	3.4k
Shingo Miyamoto Japan	29	1.4k 0.7×	888 0.7×	534 0.7×	345 0.9×	793 2.4×	118	3.7k
Douglas Lazarus United States	20	1.5k 0.7×	774 0.6×	399 0.5×	404 1.1×	168 0.5×	38	2.7k

Countries citing papers authored by James W. Freeman

Since Specialization

Citations

This map shows the geographic impact of James W. Freeman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James W. Freeman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James W. Freeman more than expected).

Fields of papers citing papers by James W. Freeman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James W. Freeman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James W. Freeman. The network helps show where James W. Freeman may publish in the future.

Co-authorship network of co-authors of James W. Freeman

This figure shows the co-authorship network connecting the top 25 collaborators of James W. Freeman. A scholar is included among the top collaborators of James W. Freeman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James W. Freeman. James W. Freeman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Zhao, Shujie, et al.. (2022). Gemcitabine resistance of pancreatic cancer cells is mediated by IGF1R dependent upregulation of CD44 expression and isoform switching. Cell Death and Disease. 13(8). 682–682. 29 indexed citations

Payton‐Stewart, Florastina, et al.. (2016). Downregulation of STAT3/NF‐κB potentiates gemcitabine activity in pancreatic cancer cells. Molecular Carcinogenesis. 56(2). 402–411. 33 indexed citations

Gong, Jingjing, Jianping Xie, Roble Bedolla, et al.. (2014). Combined Targeting of STAT3/NF-κB/COX-2/EP4 for Effective Management of Pancreatic Cancer. Clinical Cancer Research. 20(5). 1259–1273. 61 indexed citations

Carew, Jennifer S., Claudia M. Espitia, Weiguo Zhao, et al.. (2013). Reolysin is a novel reovirus-based agent that induces endoplasmic reticular stress-mediated apoptosis in pancreatic cancer. Cell Death and Disease. 4(7). e728–e728. 56 indexed citations

Krishnegowda, Naveen K., et al.. (2011). Novel Function of Transcription Factor Nrf2 as an Inhibitor of RON Tyrosine Kinase Receptor-mediated Cancer Cell Invasion. Journal of Biological Chemistry. 286(37). 32115–32122. 29 indexed citations

Zhao, Shujie, Kolaparthi Venkatasubbarao, Jane Sperry, et al.. (2008). Inhibition of STAT3Tyr705 Phosphorylation by Smad4 Suppresses Transforming Growth Factor β–Mediated Invasion and Metastasis in Pancreatic Cancer Cells. Cancer Research. 68(11). 4221–4228. 98 indexed citations

deGraffenried, Linda A., Bysani Chandrasekar, William E. Friedrichs, et al.. (2004). NF-κB inhibition markedly enhances sensitivity of resistant breast cancer tumor cells to tamoxifen. Annals of Oncology. 15(6). 885–890. 111 indexed citations

DeArmond, Daniel T., Michael G. Brattain, J. Milburn Jessup, et al.. (2003). Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines. Oncogene. 22(49). 7781–7795. 51 indexed citations

Ammanamanchi, Sudhakar, James W. Freeman, & Michael G. Brattain. (2003). Acetylated Sp3 Is a Transcriptional Activator. Journal of Biological Chemistry. 278(37). 35775–35780. 113 indexed citations

10.

Venkatasubbarao, Kolaparthi, et al.. (2001). Reversion of transcriptional repression of Sp1 by 5 aza-2' deoxycytidine restores TGF-beta type II receptor expression in the pancreatic cancer cell line MIA PaCa-2.. PubMed. 61(16). 6239–47. 36 indexed citations

11.

Freeman, James W.. (2000). Loss of TGF-β signaling in epithelial-derived tumors: Mechanisms and biological consequences. 23(3). 239–244. 2 indexed citations

12.

Venkatasubbarao, Kolaparthi, Mansoor M. Ahmed, Carol Swiderski, et al.. (1998). Novel mutations in the polyadenine tract of the transforming growth factor β type II receptor gene are found in a subpopulation of human pancreatic adenocarcinomas. Genes Chromosomes and Cancer. 22(2). 138–144. 44 indexed citations

13.

Avner, Barry P., Andrew Hanly, Carolyn Mies, et al.. (1997). Discrimination of late apoptotic/necrotic cells (type III) by flow cytometry in solid tumors. Cytometry. 28(1). 81–89. 51 indexed citations

14.

Wilson, Amy L. & James W. Freeman. (1996). Regulation of P120 mRNA levels during lymphocyte stimulation: Evidence that the P120 gene shares properties with early and late genes. Journal of Cellular Biochemistry. 60(4). 458–468. 2 indexed citations

15.

Swiderski, Carol, et al.. (1995). Altered transcription control is responsible for the increased level of proliferation‐associated P120 in rapidly growing breast carcinoma. International Journal of Cancer. 60(3). 407–412. 8 indexed citations

16.

Bolton, Wade E., et al.. (1994). Expression of proliferation‐associated antigens (PCNA, p120, p145) during the reentry of G₀ cells into the cell cycle. Cytometry. 17(1). 66–74. 29 indexed citations

17.

McGrath, Patrick C., Leigh S. Hamby, & James W. Freeman. (1992). Phorbol dibutyrate plus ionomycin improves the generation of cytotoxic T cells from draining lymph nodes of patients with advanced head and neck cancer. The American Journal of Surgery. 164(6). 610–614. 8 indexed citations

18.

Vögeli, Urs, James W. Freeman, & Joseph Chappell. (1990). Purification and Characterization of an Inducible Sesquiterpene Cyclase from Elicitor-Treated Tobacco Cell Suspension Cultures. PLANT PHYSIOLOGY. 93(1). 182–187. 76 indexed citations

19.

Freeman, James W., et al.. (1989). mRNA Levels For Human Nucleolar Protein P120 in Tumor and Nontumor Cells. PubMed. 1(1). 29–34. 16 indexed citations

20.

Busch, H., R K Busch, James W. Freeman, et al.. (1987). Nucleolar G1 antigens as cancer targets. 2(3). 141–151. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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