James V. Alvarez

2.8k total citations · 1 hit paper
36 papers, 2.1k citations indexed

About

James V. Alvarez is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, James V. Alvarez has authored 36 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Molecular Biology, 22 papers in Oncology and 9 papers in Cancer Research. Recurrent topics in James V. Alvarez's work include Cytokine Signaling Pathways and Interactions (11 papers), Cancer Cells and Metastasis (9 papers) and Epigenetics and DNA Methylation (6 papers). James V. Alvarez is often cited by papers focused on Cytokine Signaling Pathways and Interactions (11 papers), Cancer Cells and Metastasis (9 papers) and Epigenetics and DNA Methylation (6 papers). James V. Alvarez collaborates with scholars based in United States, Canada and Australia. James V. Alvarez's co-authors include David A. Frank, William R. Sellers, Matthew Meyerson, Heidi Greulich, Ryan Lupo, Whei Feng, Tzu-Hsiu Chen, Pasi A. Jänne, William C. Hahn and Lewis A. Chodosh and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Clinical Investigation and Nature Communications.

In The Last Decade

James V. Alvarez

35 papers receiving 2.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants

2005 536 citations Heidi Greulich, Tzu-Hsiu Chen et al. PLoS Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
James V. Alvarez United States	21	1.1k	1.1k	636	482	293	36	2.1k
Josep Domingo‐Domenech United States	19	885 0.8×	1.2k 1.1×	593 0.9×	599 1.2×	215 0.7×	46	2.1k
Joe Stephenson United States	25	1.1k 1.0×	894 0.8×	488 0.8×	360 0.7×	429 1.5×	65	2.0k
Melissa J. LaBonte United States	27	1.3k 1.2×	1.2k 1.1×	393 0.6×	526 1.1×	368 1.3×	78	2.6k
Helmout Modjtahedi United Kingdom	30	1.4k 1.3×	1.1k 1.0×	548 0.9×	333 0.7×	268 0.9×	81	2.5k
Aya Kobayashi Japan	18	1.2k 1.1×	1.3k 1.2×	358 0.6×	536 1.1×	391 1.3×	46	2.5k
Ludovica Ciuffreda Italy	21	668 0.6×	1.4k 1.2×	373 0.6×	549 1.1×	233 0.8×	41	2.0k
Francesca Andriani Italy	20	1.0k 0.9×	1.1k 1.0×	401 0.6×	693 1.4×	199 0.7×	40	1.9k
Patricia M. McGowan Ireland	22	1.3k 1.2×	1.1k 1.0×	294 0.5×	682 1.4×	245 0.8×	33	2.3k
Yanis Boumber United States	22	699 0.6×	1.6k 1.4×	420 0.7×	471 1.0×	192 0.7×	56	2.3k
Arja Jukkola‐Vuorinen Finland	25	1.0k 0.9×	898 0.8×	341 0.5×	800 1.7×	369 1.3×	51	2.2k

Countries citing papers authored by James V. Alvarez

Since Specialization

Citations

This map shows the geographic impact of James V. Alvarez's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James V. Alvarez with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James V. Alvarez more than expected).

Fields of papers citing papers by James V. Alvarez

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James V. Alvarez. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James V. Alvarez. The network helps show where James V. Alvarez may publish in the future.

Co-authorship network of co-authors of James V. Alvarez

This figure shows the co-authorship network connecting the top 25 collaborators of James V. Alvarez. A scholar is included among the top collaborators of James V. Alvarez based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James V. Alvarez. James V. Alvarez is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Srinivasan, Sharan, et al.. (2025). APOBEC3 Activity Promotes the Survival and Evolution of Drug-Tolerant Persister Cells during EGFR Inhibitor Resistance in Lung Cancer. Cancer Research Communications. 5(5). 825–840. 3 indexed citations

Elkholi, Islam E., Amélie Robert, Jia Wu, et al.. (2025). Targeting the Dependence on PIK3C3-mTORC1 Signaling in Dormancy-Prone Breast Cancer Cells Blunts Metastasis Initiation. Cancer Research. 85(12). 2179–2198. 1 indexed citations

Ilkayeva, Olga, Jeffrey I. Everitt, James V. Alvarez, et al.. (2024). Optical imaging reveals chemotherapy-induced metabolic reprogramming of residual disease and recurrence. Science Advances. 10(14). eadj7540–eadj7540. 5 indexed citations

Qin, Xiaodi, Brock J. McKinney, Jeremy Force, et al.. (2021). APOBEC Mutagenesis Inhibits Breast Cancer Growth through Induction of T cell–Mediated Antitumor Immune Responses. Cancer Immunology Research. 10(1). 70–86. 28 indexed citations

Lin, Chao‐Chieh, Wen‐Hsuan Yang, Yi-Tzu Lin, et al.. (2021). DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway. Oncogene. 40(11). 2018–2034. 80 indexed citations

Newcomb, Rachel, et al.. (2021). Context-dependent effects of whole-genome duplication during mammary tumor recurrence. Scientific Reports. 11(1). 14932–14932. 6 indexed citations

Lin, Chao‐Chieh, Nathaniel W. Mabe, Yi-Tzu Lin, et al.. (2020). RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence. Cell Death and Differentiation. 27(7). 2234–2247. 45 indexed citations

Fox, Douglas B., et al.. (2019). Optical Imaging of Glucose Uptake and Mitochondrial Membrane Potential to Characterize Her2 Breast Tumor Metabolic Phenotypes. Molecular Cancer Research. 17(7). 1545–1555. 19 indexed citations

Walens, Andrea, et al.. (2019). CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors. eLife. 8. 150 indexed citations

10.

Damrauer, Jeffrey S., Ryan Lupo, Nathaniel W. Mabe, et al.. (2018). Foxo-dependent Par-4 Upregulation Prevents Long-term Survival of Residual Cells Following PI3K–Akt Inhibition. Molecular Cancer Research. 16(4). 599–609. 10 indexed citations

11.

Feng, Yi, Tien-Chi Pan, Dhruv K. Pant, et al.. (2014). SPSB1 Promotes Breast Cancer Recurrence by Potentiating c-MET Signaling. Cancer Discovery. 4(7). 790–803. 33 indexed citations

12.

Alvarez, James V., George K. Belka, Tien-Chi Pan, et al.. (2014). Oncogene Pathway Activation in Mammary Tumors Dictates FDG-PET Uptake. Cancer Research. 74(24). 7583–7598. 55 indexed citations

13.

Alvarez, James V., Tien-Chi Pan, Jason R. Ruth, et al.. (2013). Par-4 Downregulation Promotes Breast Cancer Recurrence by Preventing Multinucleation following Targeted Therapy. Cancer Cell. 24(1). 30–44. 68 indexed citations

14.

Chen, Chien‐Chung, Douglas B. Stairs, Robert Boxer, et al.. (2012). Autocrine prolactin induced by the Pten–Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways. Genes & Development. 26(19). 2154–2168. 82 indexed citations

15.

Chen, Chien‐Chung, Robert Boxer, Douglas B. Stairs, et al.. (2010). Akt is required for Stat5 activation and mammary differentiation. Breast Cancer Research. 12(5). R72–R72. 40 indexed citations

16.

Alvarez, James V., Heidi Greulich, William R. Sellers, Matthew Meyerson, & David A. Frank. (2006). Signal Transducer and Activator of Transcription 3 Is Required for the Oncogenic Effects of Non–Small-Cell Lung Cancer–Associated Mutations of the Epidermal Growth Factor Receptor. Cancer Research. 66(6). 3162–3168. 206 indexed citations

17.

Ishii, Yuki, James V. Alvarez, David A. Frank, et al.. (2006). Cyclin D1 Overexpression and Response to Bortezomib Treatment in a Breast Cancer Model. JNCI Journal of the National Cancer Institute. 98(17). 1238–1247. 48 indexed citations

18.

Alvarez, James V., Phillip G. Febbo, Sridhar Ramaswamy, et al.. (2005). Identification of a Genetic Signature of Activated Signal Transducer and Activator of Transcription 3 in Human Tumors. Cancer Research. 65(12). 5054–5062. 166 indexed citations

19.

Greulich, Heidi, Tzu-Hsiu Chen, Whei Feng, et al.. (2005). Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants. PLoS Medicine. 2(11). e313–e313. 536 indexed citations breakdown →

20.

Alvarez, James V. & David A. Frank. (2004). Genome-wide analysis of STAT target genes: Elucidating the mechanism of STAT-mediated oncogenesis. Cancer Biology & Therapy. 3(11). 1045–1050. 94 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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