James Heyes

3.9k total citations · 2 hit papers
17 papers, 1.9k citations indexed

About

James Heyes is a scholar working on Molecular Biology, Immunology and Genetics. According to data from OpenAlex, James Heyes has authored 17 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Molecular Biology, 6 papers in Immunology and 5 papers in Genetics. Recurrent topics in James Heyes's work include RNA Interference and Gene Delivery (14 papers), Advanced biosensing and bioanalysis techniques (9 papers) and Virus-based gene therapy research (5 papers). James Heyes is often cited by papers focused on RNA Interference and Gene Delivery (14 papers), Advanced biosensing and bioanalysis techniques (9 papers) and Virus-based gene therapy research (5 papers). James Heyes collaborates with scholars based in United States, Switzerland and Canada. James Heyes's co-authors include Ian MacLachlan, Peter Lutwyche, Lorne Palmer, Eleni Samaridou, K. Helen Bremner, Caroline J. Springer, Dan Niculescu‐Duvaz, Kieu Lam, Robert G. Cooper and Steven M. Ansell and has published in prestigious journals such as Advanced Materials, ACS Nano and Advanced Drug Delivery Reviews.

In The Last Decade

James Heyes

16 papers receiving 1.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Lipid nanoparticles for nucleic acid delivery: Current perspectives

2020 449 citations Eleni Samaridou, James Heyes et al. Advanced Drug Delivery Reviews profile →
Lyophilization provides long-term stability for a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine

2022 198 citations Hiromi Muramatsu, Kieu Lam et al. Molecular Therapy profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
James Heyes United States	12	1.7k	370	309	240	223	17	1.9k
James C. Kaczmarek United States	13	1.9k 1.1×	434 1.2×	281 0.9×	238 1.0×	220 1.0×	15	2.1k
Melissa P. Lokugamage United States	21	1.8k 1.1×	286 0.8×	295 1.0×	212 0.9×	252 1.1×	26	2.1k
Faryal F. Mir United States	8	1.4k 0.8×	304 0.8×	276 0.9×	150 0.6×	209 0.9×	8	1.6k
Yulia Eygeris United States	12	1.4k 0.9×	207 0.6×	284 0.9×	177 0.7×	252 1.1×	18	1.8k
Daryll Vanover United States	18	1.4k 0.9×	296 0.8×	336 1.1×	123 0.5×	385 1.7×	27	1.9k
Lorne Palmer Canada	15	1.7k 1.0×	401 1.1×	266 0.9×	234 1.0×	110 0.5×	24	1.8k
Xinyao Du United States	6	2.3k 1.4×	284 0.8×	411 1.3×	407 1.7×	275 1.2×	6	2.7k
Lindsay T. Johnson United States	13	2.5k 1.5×	502 1.4×	433 1.4×	328 1.4×	266 1.2×	13	2.9k
Seán M. Sullivan United States	23	1.0k 0.6×	397 1.1×	208 0.7×	132 0.6×	183 0.8×	54	1.6k
Patrick Lu United States	20	1.6k 0.9×	337 0.9×	197 0.6×	135 0.6×	223 1.0×	37	2.1k

Countries citing papers authored by James Heyes

Since Specialization

Citations

This map shows the geographic impact of James Heyes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James Heyes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James Heyes more than expected).

Fields of papers citing papers by James Heyes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James Heyes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James Heyes. The network helps show where James Heyes may publish in the future.

Co-authorship network of co-authors of James Heyes

This figure shows the co-authorship network connecting the top 25 collaborators of James Heyes. A scholar is included among the top collaborators of James Heyes based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James Heyes. James Heyes is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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17 of 17 papers shown

Sittplangkoon, Chutamath, Mohamad‐Gabriel Alameh, Patipark Kueanjinda, et al.. (2025). Effect of mRNA formulated with lipid nanoparticles on the transcriptomic and epigenetic profiles of F4/80+ liver-associated macrophages. Scientific Reports. 15(1). 1146–1146. 2 indexed citations

Alameh, Mohamad‐Gabriel, Eakachai Prompetchara, James Heyes, et al.. (2025). A heterologous prime-boost regimen using BCG and an mRNA encoding Ag85B heightens immune response in mice. Biochemical and Biophysical Research Communications. 778. 152408–152408.

Lam, Kieu, Sunny C.Y. Jeng, Kevin McClintock, et al.. (2024). Silicon Ether Ionizable Lipids Enable Potent mRNA Lipid Nanoparticles with Rapid Tissue Clearance. ACS Nano. 18(15). 10374–10387. 11 indexed citations

Lam, Kieu, Ada W. S. Leung, Mark A. Wood, et al.. (2023). Unsaturated, Trialkyl Ionizable Lipids are Versatile Lipid‐Nanoparticle Components for Therapeutic and Vaccine Applications. Advanced Materials. 35(15). 2209624–2209624. 67 indexed citations

Mahiny, Azita J., Kevin McClintock, Gábor Boros, et al.. (2023). ASL mRNA-LNP Therapeutic for the Treatment of Argininosuccinic Aciduria Enables Survival Benefit in a Mouse Model. Biomedicines. 11(6). 1735–1735. 6 indexed citations

Lam, Kieu, et al.. (2023). Optimizing Lipid Nanoparticles for Delivery in Primates. Advanced Materials. 35(26). e2211420–e2211420. 72 indexed citations

Ye, Xin, Lorne Palmer, Eleni Samaridou, et al.. (2022). Combination treatment of mannose and GalNAc conjugated small interfering RNA protects against lethal Marburg virus infection. Molecular Therapy. 31(1). 269–281. 13 indexed citations

Muramatsu, Hiromi, Kieu Lam, Csaba Bajusz, et al.. (2022). Lyophilization provides long-term stability for a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine. Molecular Therapy. 30(5). 1941–1951. 198 indexed citations breakdown →

Lam, Kieu, Xin Ye, A. D. Martin, et al.. (2021). Ligand conjugate SAR and enhanced delivery in NHP. Molecular Therapy. 29(10). 2910–2919. 8 indexed citations

10.

Samaridou, Eleni, James Heyes, & Peter Lutwyche. (2020). Lipid nanoparticles for nucleic acid delivery: Current perspectives. Advanced Drug Delivery Reviews. 154-155. 37–63. 449 indexed citations breakdown →

11.

Heyes, James, et al.. (2007). Lipid Encapsulation Enables the Effective Systemic Delivery of Polyplex Plasmid DNA. Molecular Therapy. 15(4). 713–720. 71 indexed citations

12.

Heyes, James, et al.. (2006). Synthesis and characterization of novel poly(ethylene glycol)-lipid conjugates suitable for use in drug delivery. Journal of Controlled Release. 112(2). 280–290. 100 indexed citations

13.

Ambegia, Ellen, Steven M. Ansell, P.R. Cullis, et al.. (2005). Stabilized plasmid–lipid particles containing PEG-diacylglycerols exhibit extended circulation lifetimes and tumor selective gene expression. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1669(2). 155–163. 171 indexed citations

14.

Heyes, James, Lorne Palmer, K. Helen Bremner, & Ian MacLachlan. (2005). Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids. Journal of Controlled Release. 107(2). 276–287. 469 indexed citations

15.

Niculescu‐Duvaz, Dan, James Heyes, & Caroline J. Springer. (2003). Structure-Activity Relationship in Cationic Lipid Mediated Gene Transfection. Current Medicinal Chemistry. 10(14). 1233–1261. 127 indexed citations

16.

Heyes, James, Dan Niculescu‐Duvaz, Robert G. Cooper, & Caroline J. Springer. (2001). Synthesis of Novel Cationic Lipids: Effect of Structural Modification on the Efficiency of Gene Transfer. Journal of Medicinal Chemistry. 45(1). 99–114. 134 indexed citations

17.

Niculescu‐Duvaz, Ion, et al.. (1999). Recent developments in gene-directed enzyme prodrug therapy (GDEPT) for cancer.. PubMed. 1(4). 480–6. 17 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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