James C. Fredenburgh

4.4k total citations · 2 hit papers
79 papers, 3.4k citations indexed

About

James C. Fredenburgh is a scholar working on Hematology, Cardiology and Cardiovascular Medicine and Pulmonary and Respiratory Medicine. According to data from OpenAlex, James C. Fredenburgh has authored 79 papers receiving a total of 3.4k indexed citations (citations by other indexed papers that have themselves been cited), including 60 papers in Hematology, 21 papers in Cardiology and Cardiovascular Medicine and 20 papers in Pulmonary and Respiratory Medicine. Recurrent topics in James C. Fredenburgh's work include Blood Coagulation and Thrombosis Mechanisms (55 papers), Blood properties and coagulation (20 papers) and Coagulation, Bradykinin, Polyphosphates, and Angioedema (19 papers). James C. Fredenburgh is often cited by papers focused on Blood Coagulation and Thrombosis Mechanisms (55 papers), Blood properties and coagulation (20 papers) and Coagulation, Bradykinin, Polyphosphates, and Angioedema (19 papers). James C. Fredenburgh collaborates with scholars based in Canada, United States and Australia. James C. Fredenburgh's co-authors include Jeffrey I. Weitz, Alan R. Stafford, John W. Eikelboom, Iqbal Jaffer, J. Hirsh, Beverly A. Leslie, Michael E. Nesheim, Jonathan W. Yau, Trang Vu and Peng Liao and has published in prestigious journals such as Journal of Biological Chemistry, Circulation and SHILAP Revista de lepidopterología.

In The Last Decade

James C. Fredenburgh

76 papers receiving 3.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Medical device‐induced thrombosis: what causes it and how can we prevent it?

2015 424 citations Iqbal Jaffer, James C. Fredenburgh et al. Journal of Thrombosis and Haemostasis profile →
A Test in Context: D-Dimer

2017 374 citations Jeffrey I. Weitz, James C. Fredenburgh et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
James C. Fredenburgh Canada	34	1.4k	757	654	575	565	79	3.4k
Nicola J. Mutch United Kingdom	28	1.6k 1.1×	416 0.5×	892 1.4×	1.0k 1.8×	360 0.6×	67	3.6k
Jolyon Jesty United States	34	1.5k 1.1×	799 1.1×	612 0.9×	489 0.9×	517 0.9×	83	3.2k
Thomas Orfeo United States	29	1.1k 0.8×	294 0.4×	446 0.7×	347 0.6×	839 1.5×	73	3.3k
Theo Lindhout Netherlands	29	1.7k 1.2×	540 0.7×	518 0.8×	339 0.6×	471 0.8×	68	2.8k
William P. Fay United States	39	1.8k 1.3×	1.1k 1.4×	999 1.5×	424 0.7×	1.2k 2.1×	93	5.5k
M. Anna Kowalska United States	37	2.0k 1.4×	417 0.6×	453 0.7×	434 0.8×	1.3k 2.4×	113	4.9k
Duncan S. Pepper United Kingdom	37	1.5k 1.1×	546 0.7×	705 1.1×	285 0.5×	980 1.7×	128	4.1k
Shirley K. Wrobleski United States	30	1.5k 1.1×	785 1.0×	553 0.8×	230 0.4×	942 1.7×	58	4.4k
G. Müller‐Berghaus Germany	31	1.8k 1.3×	871 1.2×	821 1.3×	292 0.5×	626 1.1×	111	4.7k
Frederick A. Ofosu Canada	40	2.8k 1.9×	1.4k 1.8×	619 0.9×	464 0.8×	663 1.2×	162	5.2k

Countries citing papers authored by James C. Fredenburgh

Since Specialization

Citations

This map shows the geographic impact of James C. Fredenburgh's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James C. Fredenburgh with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James C. Fredenburgh more than expected).

Fields of papers citing papers by James C. Fredenburgh

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James C. Fredenburgh. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James C. Fredenburgh. The network helps show where James C. Fredenburgh may publish in the future.

Co-authorship network of co-authors of James C. Fredenburgh

This figure shows the co-authorship network connecting the top 25 collaborators of James C. Fredenburgh. A scholar is included among the top collaborators of James C. Fredenburgh based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James C. Fredenburgh. James C. Fredenburgh is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Fredenburgh, James C., et al.. (2024). Histidine-Rich Glycoprotein Modulates the Toxic Effects of High-Dose Polyphosphate in Mice. Arteriosclerosis Thrombosis and Vascular Biology. 44(7). 1658–1670.

Fredenburgh, James C., et al.. (2023). Allosteric modulation of exosite 1 attenuates polyphosphate-catalyzed activation of factor XI by thrombin. Journal of Thrombosis and Haemostasis. 21(1). 83–93. 3 indexed citations

Liao, Peng, et al.. (2023). Histidine-rich glycoprotein attenuates catheter thrombosis. Blood Advances. 7(18). 5651–5660. 7 indexed citations

Fredenburgh, James C. & Jeffrey I. Weitz. (2023). News at XI: moving beyond factor Xa inhibitors. Journal of Thrombosis and Haemostasis. 21(7). 1692–1702. 27 indexed citations

Fredenburgh, James C., et al.. (2021). Identification of the histidine‐rich glycoprotein domains responsible for contact pathway inhibition. Journal of Thrombosis and Haemostasis. 20(4). 821–832. 6 indexed citations

Zhou, Ji, et al.. (2021). Polyphosphate-induced thrombosis in mice is factor XII dependent and is attenuated by histidine-rich glycoprotein. Blood Advances. 5(18). 3540–3551. 19 indexed citations

Fredenburgh, James C. & Jeffrey I. Weitz. (2020). New anticoagulants: Moving beyond the direct oral anticoagulants. Journal of Thrombosis and Haemostasis. 19(1). 20–29. 48 indexed citations

Jaffer, Iqbal, James C. Fredenburgh, Alan R. Stafford, Richard Whitlock, & Jeffrey I. Weitz. (2019). Rivaroxaban and Dabigatran for Suppression of Mechanical Heart Valve–Induced Thrombin Generation. The Annals of Thoracic Surgery. 110(2). 582–590. 12 indexed citations

Jaffer, Iqbal, James C. Fredenburgh, J. Hirsh, & Jeffrey I. Weitz. (2015). Medical device‐induced thrombosis: what causes it and how can we prevent it?. Journal of Thrombosis and Haemostasis. 13. S72–S81. 424 indexed citations breakdown →

10.

Kim, Paul Y., Trang Vu, Beverly A. Leslie, et al.. (2014). Reduced Plasminogen Binding and Delayed Activation Render γ′-Fibrin More Resistant to Lysis than γA-Fibrin. Journal of Biological Chemistry. 289(40). 27494–27503. 8 indexed citations

11.

Yau, Jonathan W., Alan R. Stafford, Peng Liao, et al.. (2012). Corn trypsin inhibitor coating attenuates the prothrombotic properties of catheters in vitro and in vivo. Acta Biomaterialia. 8(11). 4092–4100. 66 indexed citations

12.

Yau, Jonathan W., Alan R. Stafford, Peng Liao, et al.. (2011). Mechanism of catheter thrombosis: comparison of the antithrombotic activities of fondaparinux, enoxaparin, and heparin in vitro and in vivo. Blood. 118(25). 6667–6674. 84 indexed citations

13.

Kim, Paul Y., et al.. (2011). A High Affinity Interaction of Plasminogen with Fibrin Is Not Essential for Efficient Activation by Tissue-type Plasminogen Activator. Journal of Biological Chemistry. 287(7). 4652–4661. 35 indexed citations

14.

Vu, Trang, Alan R. Stafford, Beverly A. Leslie, et al.. (2011). Histidine-rich Glycoprotein Binds Fibrin(ogen) with High Affinity and Competes with Thrombin for Binding to the γ′-Chain. Journal of Biological Chemistry. 286(35). 30314–30323. 31 indexed citations

15.

Stafford, Alan R., et al.. (2009). Long Range Communication between Exosites 1 and 2 Modulates Thrombin Function. Journal of Biological Chemistry. 284(38). 25620–25629. 69 indexed citations

16.

Fredenburgh, James C.. (2002). Antithrombin-Independent Anticoagulation by Hypersulfated Low-Molecular-Weight Heparin. Trends in Cardiovascular Medicine. 12(7). 281–287. 8 indexed citations

17.

Anderson, Julia A. M., James C. Fredenburgh, Alan R. Stafford, et al.. (2001). Hypersulfated Low Molecular Weight Heparin with Reduced Affinity for Antithrombin Acts as an Anticoagulant by Inhibiting Intrinsic Tenase and Prothrombinase. Journal of Biological Chemistry. 276(13). 9755–9761. 21 indexed citations

18.

Liaw, Patricia C., Richard C. Austin, James C. Fredenburgh, Alan R. Stafford, & Jeffrey I. Weitz. (1999). Comparison of Heparin- and Dermatan Sulfate-mediated Catalysis of Thrombin Inactivation by Heparin Cofactor II. Journal of Biological Chemistry. 274(39). 27597–27604. 46 indexed citations

19.

Weitz, Jeffrey I., Edward Young, Marilyn Johnston, et al.. (1999). Vasoflux, a New Anticoagulant With a Novel Mechanism of Action. Circulation. 99(5). 682–689. 30 indexed citations

20.

Stewart, R. J. C., James C. Fredenburgh, & Jeffrey I. Weitz. (1998). Characterization of the Interactions of Plasminogen and Tissue and Vampire Bat Plasminogen Activators with Fibrinogen, Fibrin, and the Complex of d-Dimer Noncovalently Linked to Fragment E. Journal of Biological Chemistry. 273(29). 18292–18299. 32 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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