J A Bluestone

7.7k citations

29 papers · 6.4k indexed · 3 hit papers · h-index 18

Impact in

Immunology top 0.2%
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Immune Response and Inflammation
Oncology top 2%
- Cancer Immunotherapy and Biomarkers
- CAR-T cell therapy research

Papers in ⓘ

Immunology 20
- T-cell and B-cell Immunology 16
- Immune Cell Function and Interaction 12
- Immunotherapy and Immune Responses 5
Radiology, Nuclear Medicine and Imaging 11
- Monoclonal and Polyclonal Antibodies Research 11

Co-authors: Arlene H. Sharpe (2 shared papers)Alain Schweitzer (1 shared paper)William P. Lynch (1 shared paper)Elizabeth Tivol (1 shared paper)Frank Borriello (1 shared paper)Deborah J. Lenschow (3 shared papers)Lesley Rhee (2 shared papers)Benoı̂t L. Salomon (1 shared paper)
Journals: The Journal of Experimental Medicine (4 papers)The Journal of Immunology (4 papers)Immunity (3 papers)Proceedings of the National Academy of Sciences (2 papers)iScience (1 paper)
Partner nations: United States France Hungary

In The Last Decade

J A Bluestone

28 papers receiving 6.2k citations

Hit Papers

align trajectories log scale

B7/CD28 Costimulation Is Essential for the Homeostasis of the CD4+CD25+ Immunoregulatory T Cells that Control Autoimmune Diabetes 2000 · 1.7k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2000 Immunity
1995 Immunity
1995 The Journal of Experimental Medicine

Peers

Countries citing papers authored by J A Bluestone

Since Specialization

Citations

This map shows the geographic impact of J A Bluestone's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by J A Bluestone with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites J A Bluestone more than expected).

Fields of papers citing papers by J A Bluestone

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by J A Bluestone. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by J A Bluestone. The network helps show where J A Bluestone may publish in the future.

Co-authors

The 25 scholars most cited alongside J A Bluestone, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with J A Bluestone Line = papers co-authored together J A Bluestone links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 29 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4 Immunity ·Elizabeth Tivol, Frank Borriello, Alain Schweitzer, William P. Lynch, J A Bluestone, Arlene H. Sharpe Hit paper breakdown →	1995	2320
2	B7/CD28 Costimulation Is Essential for the Homeostasis of the CD4+CD25+ Immunoregulatory T Cells that Control Autoimmune Diabetes Immunity ·Benoı̂t L. Salomon, Deborah J. Lenschow, Lesley Rhee, Neda Ashourian, Bhagirath Singh, Arlene H. Sharpe, J A Bluestone Hit paper breakdown →	2000	1702
3	Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse. The Journal of Experimental Medicine ·Deborah J. Lenschow, Shu‐Chuan Ho, Husain Sattar, Lesley Rhee, G S Gray, N Nabavi, Kevan C. Herold, J A Bluestone Hit paper breakdown →	1995	518
4	New perspectives of C1328-137-mediated T cell costimulation Immunity ·J A Bluestone	1995	447
5	CTLA-4: a negative regulator of autoimmune disease. The Journal of Experimental Medicine ·Nitin J. Karandikar, Carol L. Vanderlugt, Theresa L. Walunas, Stephen D. Miller, J A Bluestone	1996	323
6	Distinct roles of CTLA‐4 and TGF‐β in CD4⁺CD25⁺ regulatory T cell function European Journal of Immunology ·Qizhi Tang, Elisa K. Boden, Kammi Henriksen, (unknown), Mingying Bi, J A Bluestone	2004	303
7	Expression and functional significance of an additional ligand for CTLA-4. Proceedings of the National Academy of Sciences ·Deborah J. Lenschow, Gloria H. Su, L Zuckerman, N Nabavi, C L Jellis, G S Gray, Jim Miller, J A Bluestone	1993	231
8	Signaling through CD28 and CTLA-4 controls two distinct forms of T cell anergy Journal of Clinical Investigation ·Andrew D. Wells, Matthew C. Walsh, J A Bluestone, Laurence A. Turka	2001	143
9	T cell inactivation and cytokine deviation promoted by anti-CD3 mAbs Current Opinion in Immunology ·Judith A. Smith, J A Bluestone	1997	54
10	Targeting the B7/CD28:CTLA-4 costimulatory system in CNS autoimmune disease Journal of Neuroimmunology ·Nitin J. Karandikar, Carol L. Vanderlugt, J A Bluestone, Stephen D. Miller	1998	46
11	T cell antigen receptor phosphorylation induced by an anti-receptor antibody. The Journal of Immunology ·Lawrence E. Samelson, J J O'Shea, H Luong, P Ross, Kevin B. Urdahl, Richard D. Klausner, J A Bluestone	1987	46
12	Nonmitogenic anti-CD3F(ab’)2 fragments inhibit lethal murine graft-versus-host disease induced across the major histocompatibility barrier The Journal of Immunology ·Bruce R. Blazar, Patricia A. Taylor, Dale C. Snover, J A Bluestone, Daniel A. Vallera	1993	40
13	In vitro and in vivo activation of murine γ/δ T cells induces the expression of IgA, IgM, and IgG Fc receptors The Journal of Immunology ·Mátyás Sándor, Bronwyn A. Houlden, J A Bluestone, Stephen Μ. Hedrick, Janet Weinstock, Richard G. Lynch	1992	33
14	Costimulation and its role in organ transplantation Clinical Transplantation ·J A Bluestone	1996	30
15	Treatment with monoclonal anti-CD3 antibody protects against lethal Sendai virus infection by induction of natural killer cells. The Journal of Immunology ·W. Martin Kast, J A Bluestone, Mirjam H.M. Heemskerk, Joke Spaargaren, Arie C. Voordouw, Joshua D.I. Ellenhorn, C J Melief	1990	24
16	Phenotypic and functional analysis of positive selection in the gamma/delta T cell lineage. The Journal of Experimental Medicine ·F B Wells, Yoichi Tatsumi, J A Bluestone, Stephen Μ. Hedrick, James P. Allison, Louis A. Matis	1993	21
17	Cloned cytotoxic T lymphocytes that recognize an I-A region product in the context of a class I antigen. The Journal of Experimental Medicine ·Nobukata Shinohara, J A Bluestone, David H. Sachs	1986	20
18	Serological analysis of H-2 mutations using monoclonal antibodies. PubMed ·J A Bluestone, Ian F. C. McKenzie, Roger W. Melvold, Keiko Ozato, Mauro S. Sandrin, S O Sharrow, David H. Sachs	1985	18
19	Suppression of the Immune Response in Tumor-Bearing Mice. II. Characterization of Adherent Suppressor Cells<xref ref-type="fn" rid="FN2">2</xref> JNCI Journal of the National Cancer Institute ·J A Bluestone, Cesar A. Lopez	1979	14
20	Anti-idiotypes against anti-H-2 monoclonal antibodies: structural analysis of the molecules induced by in vivo anti-idiotype treatment. Proceedings of the National Academy of Sciences ·J A Bluestone, Henry C. Krutzsch, H Auchincloss, Pierre‐André Cazenave, Thomas J. Kindt, D H Sachs	1982	13

About J A Bluestone

J A Bluestone is a scholar working on Immunology, Radiology, Nuclear Medicine and Imaging, Transplantation, Genetics and Immunology and Allergy, having authored 29 papers that have together received 6.4k indexed citations. Recurring topics across this work include T-cell and B-cell Immunology (16 papers), Immune Cell Function and Interaction (12 papers), Monoclonal and Polyclonal Antibodies Research (11 papers), Diabetes and associated disorders (8 papers), Pancreatic function and diabetes (5 papers), Immunotherapy and Immune Responses (5 papers), Diabetes Management and Research (2 papers) and CAR-T cell therapy research (2 papers). The work is most often cited by research in Immunology (5.2k citations), Oncology (1.6k citations), Genetics (1.2k citations), Transplantation (101 citations) and Immunology and Allergy (178 citations). J A Bluestone has collaborated with scholars based in United States, France and Hungary. Frequent co-authors include Arlene H. Sharpe, Alain Schweitzer, William P. Lynch, Elizabeth Tivol, Frank Borriello, Deborah J. Lenschow, Lesley Rhee, Benoı̂t L. Salomon, Bhagirath Singh and G S Gray. Their work appears in journals such as The Journal of Experimental Medicine, The Journal of Immunology, Immunity, Proceedings of the National Academy of Sciences and iScience.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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