Isabella A. Graef

7.2k total citations · 3 hit papers
39 papers, 5.8k citations indexed

About

Isabella A. Graef is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Immunology. According to data from OpenAlex, Isabella A. Graef has authored 39 papers receiving a total of 5.8k indexed citations (citations by other indexed papers that have themselves been cited), including 34 papers in Molecular Biology, 11 papers in Cellular and Molecular Neuroscience and 8 papers in Immunology. Recurrent topics in Isabella A. Graef's work include Signaling Pathways in Disease (22 papers), Amyloidosis: Diagnosis, Treatment, Outcomes (6 papers) and Calpain Protease Function and Regulation (4 papers). Isabella A. Graef is often cited by papers focused on Signaling Pathways in Disease (22 papers), Amyloidosis: Diagnosis, Treatment, Outcomes (6 papers) and Calpain Protease Function and Regulation (4 papers). Isabella A. Graef collaborates with scholars based in United States, Japan and Austria. Isabella A. Graef's co-authors include Robert H. Crabtree, Gerald R. Crabtree, Joel R. Neilson, Haiyan Wu, Ann Kuo, Kryn Stankunas, Jiang Wu, Julie Lessard, Jason E. Gestwicki and Monte M. Winslow and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Isabella A. Graef

38 papers receiving 5.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Mechanism of Action of Cyclosporin A and FK506

1996 562 citations Steffan N. Ho, Neil A. Clipstone et al. Clinical Immunology and Immunopathology profile →
An Essential Switch in Subunit Composition of a Chromatin Remodeling Complex during Neural Development

2007 559 citations Julie Lessard, Jiang Wu et al. Neuron profile →
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21

2006 539 citations Joseph R. Arron, Monte M. Winslow et al. Nature profile →

Peers

Isabella A. Graef

IMMUN

CMN

ONCOL

Wai T. Wong United States

Yasuyuki Ohkawa Japan

Bernd Nürnberg Germany

Edward D. Lamperti United States

Paul K. Brindle United States

Sally A. Cowley United Kingdom

Robert A. Hipskind France

Paul K. Goldsmith United States

Rejean L. Idzerda United States

Ajamete Kaykas United States

Wai T. Wong United States

Isabella A. Graef

4.1k ×1.0

1.1k ×1.2

IMMUN

1.4k ×1.5

CMN

409 ×0.6

ONCOL

697 ×1.2

Citations per year, relative to Isabella A. Graef Isabella A. Graef (= 1×) peers Wai T. Wong

Countries citing papers authored by Isabella A. Graef

Since Specialization

Citations

This map shows the geographic impact of Isabella A. Graef's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Isabella A. Graef with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Isabella A. Graef more than expected).

Fields of papers citing papers by Isabella A. Graef

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Isabella A. Graef. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Isabella A. Graef. The network helps show where Isabella A. Graef may publish in the future.

Co-authorship network of co-authors of Isabella A. Graef

This figure shows the co-authorship network connecting the top 25 collaborators of Isabella A. Graef. A scholar is included among the top collaborators of Isabella A. Graef based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Isabella A. Graef. Isabella A. Graef is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Ji, Alan X., et al.. (2023). Acoramidis produces near-complete TTR stabilization in blood samples from patients with variant transthyretin amyloidosis that is greater than that achieved with tafamidis. European Heart Journal. 44(Supplement_2). 3 indexed citations

Hagihara, Hideo, Hirotaka Shoji, Mahomi Kuroiwa, et al.. (2022). Forebrain-specific conditional calcineurin deficiency induces dentate gyrus immaturity and hyper-dopaminergic signaling in mice. Molecular Brain. 15(1). 94–94. 5 indexed citations

Priya, Rashi, Mercedes F. Paredes, Theofanis Karayannis, et al.. (2018). Activity Regulates Cell Death within Cortical Interneurons through a Calcineurin-Dependent Mechanism. Cell Reports. 22(7). 1695–1709. 71 indexed citations

Davila, Jonathan, et al.. (2014). Calcineurin Signaling Regulates Neural Induction through Antagonizing the BMP Pathway. Neuron. 82(1). 109–124. 25 indexed citations

Connelly, Stephen, Yu Wang, Lei Zhao, et al.. (2013). AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin. Proceedings of the National Academy of Sciences. 110(24). 9992–9997. 144 indexed citations

Kao, Shih-Chu, Haiyan Wu, Jianming Xie, et al.. (2009). Calcineurin/NFAT Signaling Is Required for Neuregulin-Regulated Schwann Cell Differentiation. Science. 323(5914). 651–654. 171 indexed citations

Wu, Jiang, Julie Lessard, Ivan Olave, et al.. (2007). Regulation of Dendritic Development by Neuron-Specific Chromatin Remodeling Complexes. Neuron. 56(1). 94–108. 298 indexed citations

Wu, Haiyan, Alys Peisley, Isabella A. Graef, & Robert H. Crabtree. (2007). NFAT signaling and the invention of vertebrates. Trends in Cell Biology. 17(6). 251–260. 152 indexed citations

Lessard, Julie, Jiang Wu, Jeffrey A. Ranish, et al.. (2007). An Essential Switch in Subunit Composition of a Chromatin Remodeling Complex during Neural Development. Neuron. 55(2). 201–215. 559 indexed citations breakdown →

10.

Arron, Joseph R., Monte M. Winslow, Ching-Pin Chang, et al.. (2006). NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21. Nature. 441(7093). 595–600. 539 indexed citations breakdown →

11.

Graef, Isabella A., Fan Wang, Frédéric Charron, et al.. (2003). Neurotrophins and Netrins Require Calcineurin/NFAT Signaling to Stimulate Outgrowth of Embryonic Axons. Cell. 113(5). 657–670. 313 indexed citations

12.

Graef, Isabella A., et al.. (2001). NFAT signaling in vertebrate development. Current Opinion in Genetics & Development. 11(5). 505–512. 175 indexed citations

13.

Sabapathy, Kanaga, Tuula Kallunki, Jean‐Pierre David, et al.. (2001). C-Jun Nh2-Terminal Kinase (Jnk)1 and Jnk2 Have Similar and Stage-Dependent Roles in Regulating T Cell Apoptosis and Proliferation. The Journal of Experimental Medicine. 193(3). 317–328. 190 indexed citations

14.

Graef, Isabella A., et al.. (2001). Signals Transduced by Ca2+/Calcineurin and NFATc3/c4 Pattern the Developing Vasculature. Cell. 105(7). 863–875. 355 indexed citations

15.

Graef, Isabella A., P. Mermelstein, Kryn Stankunas, et al.. (1999). L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons. Nature. 401(6754). 703–708. 440 indexed citations

16.

Stankunas, Kryn, et al.. (1999). Signaling through Calcium, Calcineurin, and NF-AT in Lymphocyte Activation and Development. Cold Spring Harbor Symposia on Quantitative Biology. 64(0). 505–516. 24 indexed citations

17.

Holsinger, Leslie J., Isabella A. Graef, Wojciech Swat, et al.. (1998). Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction. Current Biology. 8(10). 563–573. 367 indexed citations

18.

Graef, Isabella A.. (1997). Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP70. The EMBO Journal. 16(18). 5618–5628. 64 indexed citations

19.

Ho, Steffan N., Neil A. Clipstone, Jeffrey P. Northrop, et al.. (1996). The Mechanism of Action of Cyclosporin A and FK506. Clinical Immunology and Immunopathology. 80(3). S40–S45. 562 indexed citations breakdown →

20.

Falk, Kirsten, Olaf Rötzschke, Stefan Faath, et al.. (1993). Both Human and Mouse Cells Expressing H-2Kb and Ovalbumin Process the Same Peptide, SIINFEKL. Cellular Immunology. 150(2). 447–452. 24 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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