Isaac E. García

997 total citations · 1 hit paper
21 papers, 804 citations indexed

About

Isaac E. García is a scholar working on Molecular Biology, Genetics and Sensory Systems. According to data from OpenAlex, Isaac E. García has authored 21 papers receiving a total of 804 indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 7 papers in Genetics and 3 papers in Sensory Systems. Recurrent topics in Isaac E. García's work include Connexins and lens biology (17 papers), Nicotinic Acetylcholine Receptors Study (11 papers) and Yersinia bacterium, plague, ectoparasites research (7 papers). Isaac E. García is often cited by papers focused on Connexins and lens biology (17 papers), Nicotinic Acetylcholine Receptors Study (11 papers) and Yersinia bacterium, plague, ectoparasites research (7 papers). Isaac E. García collaborates with scholars based in Chile, United States and Brazil. Isaac E. García's co-authors include Carlos González, Amaury Pupo, Mauricio A. Retamal, Bernardo I. Pinto, Jimmy Stehberg, Rodrigo Del Río, Agustı́n D. Martı́nez, Oscar Jara, Tomás Pérez‐Acle and Juan C. Sáez and has published in prestigious journals such as Journal of Biological Chemistry, Scientific Reports and The FASEB Journal.

In The Last Decade

Isaac E. García

20 papers receiving 800 citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Extracellular Cysteine in Connexins: Role as Redox Sensors

2016 437 citations Mauricio A. Retamal, Isaac E. García et al. Frontiers in Physiology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Isaac E. García Chile	12	435	95	84	70	64	21	804
Amaury Pupo United States	17	677 1.6×	197 2.1×	81 1.0×	31 0.4×	107 1.7×	36	1.3k
Bernardo I. Pinto Chile	11	339 0.8×	71 0.7×	80 1.0×	23 0.3×	171 2.7×	17	825
Alina Beraudi Italy	16	424 1.0×	83 0.9×	135 1.6×	25 0.4×	74 1.2×	35	1.2k
Shu‐Rong Wang China	23	232 0.5×	36 0.4×	78 0.9×	27 0.4×	176 2.8×	76	1.5k
Myeung Ju Kim South Korea	25	383 0.9×	184 1.9×	257 3.1×	80 1.1×	327 5.1×	97	1.6k
Paul A. Weber United States	17	360 0.8×	48 0.5×	48 0.6×	28 0.4×	65 1.0×	54	1.1k
Ryota Matsuo Japan	23	322 0.7×	57 0.6×	65 0.8×	164 2.3×	499 7.8×	94	1.6k
Ivana Y. Kuo United States	18	812 1.9×	531 5.6×	151 1.8×	52 0.7×	155 2.4×	38	1.3k
Hisao Yamaguchi Japan	17	260 0.6×	46 0.5×	160 1.9×	18 0.3×	98 1.5×	103	962
Jonathan E. Cohen United States	21	455 1.0×	64 0.7×	85 1.0×	29 0.4×	302 4.7×	28	1.0k

Countries citing papers authored by Isaac E. García

Since Specialization

Citations

This map shows the geographic impact of Isaac E. García's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Isaac E. García with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Isaac E. García more than expected).

Fields of papers citing papers by Isaac E. García

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Isaac E. García. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Isaac E. García. The network helps show where Isaac E. García may publish in the future.

Co-authorship network of co-authors of Isaac E. García

This figure shows the co-authorship network connecting the top 25 collaborators of Isaac E. García. A scholar is included among the top collaborators of Isaac E. García based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Isaac E. García. Isaac E. García is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Minogue, Peter J., Jaime Maripillán, Isaac E. García, et al.. (2024). Connexin channels and hemichannels are modulated differently by charge reversal at residues forming the intracellular pocket. Biological Research. 57(1). 31–31.

García, Isaac E., Jaime Maripillán, Tomás Pérez‐Acle, et al.. (2023). Expression of KID syndromic mutation Cx26S17F produces hyperactive hemichannels in supporting cells of the organ of Corti. Frontiers in Cell and Developmental Biology. 10. 1071202–1071202. 5 indexed citations

González‐Arriagada, Wilfredo Alejandro, Ricardo D. Coletta, C.M. Garcia, et al.. (2023). CCR5/CCL5 axis is linked to a poor outcome, and inhibition reduces metastasis in oral squamous cell carcinoma. Journal of Cancer Research and Clinical Oncology. 149(19). 17335–17346. 4 indexed citations

Moreira, Danielle de Paula, Isaac E. García, Francisco Aboitiz, et al.. (2022). Mutations in trpγ, the homologue of TRPC6 autism candidate gene, causes autism-like behavioral deficits in Drosophila. Molecular Psychiatry. 27(8). 3328–3342. 12 indexed citations

González‐Arriagada, Wilfredo Alejandro, Isaac E. García, Rene Flores, Sebastián Morales, & Ricardo D. Coletta. (2022). Therapeutic Perspectives of HIV-Associated Chemokine Receptor (CCR5 and CXCR4) Antagonists in Carcinomas. International Journal of Molecular Sciences. 24(1). 478–478. 5 indexed citations

Maripillán, Jaime, Helmuth A. Sánchez, Caroline Weinstein‐Oppenheimer, et al.. (2021). Restraint of Human Skin Fibroblast Motility, Migration, and Cell Surface Actin Dynamics, by Pannexin 1 and P2X7 Receptor Signaling. International Journal of Molecular Sciences. 22(3). 1069–1069. 11 indexed citations

García, Isaac E., Gustavo F. Contreras, Amaury Pupo, et al.. (2018). The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels. The Journal of General Physiology. 150(5). 697–711. 20 indexed citations

Chatterjee, Payal, Isaac E. García, Wesley M. Botello‐Smith, et al.. (2018). The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening. The Journal of General Physiology. 151(3). 328–341. 14 indexed citations

Chatterjee, Payal, et al.. (2018). Insights on Gating Functions of Cytosolic Domains of Connexin26 Hemichannels Revealed by a Human Pathogenic Mutation (N14K). Biophysical Journal. 114(3). 379a–379a. 1 indexed citations

10.

Pinto, Bernardo I., Amaury Pupo, Isaac E. García, et al.. (2017). Calcium binding and voltage gating in Cx46 hemichannels. Scientific Reports. 7(1). 15851–15851. 15 indexed citations

11.

García, Isaac E., Helmuth A. Sánchez, Agustı́n D. Martı́nez, & Mauricio A. Retamal. (2017). Redox-mediated regulation of connexin proteins; focus on nitric oxide. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1860(1). 91–95. 23 indexed citations

12.

Pinto, Bernardo I., Isaac E. García, Amaury Pupo, et al.. (2016). Charged Residues at the First Transmembrane Region Contribute to the Voltage Dependence of the Slow Gate of Connexins. Journal of Biological Chemistry. 291(30). 15740–15752. 11 indexed citations

13.

Retamal, Mauricio A., Isaac E. García, Bernardo I. Pinto, et al.. (2016). Extracellular Cysteine in Connexins: Role as Redox Sensors. Frontiers in Physiology. 7. 1–1. 437 indexed citations breakdown →

14.

García, Isaac E., Pavel Prado, Amaury Pupo, et al.. (2016). Connexinopathies: a structural and functional glimpse. BMC Cell Biology. 17(S1). 17–17. 37 indexed citations

15.

García, Isaac E., Amaury Pupo, Oscar Jara, et al.. (2016). From Hyperactive Connexin26 Hemichannels to Impairments in Epidermal Calcium Gradient and Permeability Barrier in the Keratitis-Ichthyosis-Deafness Syndrome. Journal of Investigative Dermatology. 136(3). 574–583. 40 indexed citations

16.

García, Isaac E., Jaime Maripillán, Oscar Jara, et al.. (2015). Keratitis-Ichthyosis-Deafness Syndrome-Associated Cx26 Mutants Produce Nonfunctional Gap Junctions but Hyperactive Hemichannels When Co-Expressed With Wild Type Cx43. Journal of Investigative Dermatology. 135(5). 1338–1347. 70 indexed citations

17.

Araya-Secchi, Raúl, Tomás Pérez‐Acle, Seung-Gu Kang, et al.. (2014). Characterization of a Novel Water Pocket Inside the Human Cx26 Hemichannel Structure. Biophysical Journal. 107(3). 599–612. 40 indexed citations

18.

García, Isaac E., Mauricio A. Retamal, Oscar Jara, Carlos González, & Agustı́n D. Martı́nez. (2013). Is the Gain of Hemichannel Activity a Common Feature Shared by Cx26 Syndromic Deafness Mutants?. Biophysical Journal. 104(2). 492a–493a. 1 indexed citations

19.

Jara, Oscar, Rodrigo Acuña, Isaac E. García, et al.. (2012). Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function. Molecular Biology of the Cell. 23(17). 3299–3311. 35 indexed citations

20.

Cárdenas, César, Jorge A. Bevilacqua, Isaac E. García, et al.. (2010). Abnormal distribution of inositol 1,4,5‐trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy‐derived cells. The FASEB Journal. 24(9). 3210–3221. 20 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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