Isaac B. Hilton

4.8k total citations · 2 hit papers
25 papers, 3.0k citations indexed

About

Isaac B. Hilton is a scholar working on Molecular Biology, Oncology and Aging. According to data from OpenAlex, Isaac B. Hilton has authored 25 papers receiving a total of 3.0k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 5 papers in Oncology and 4 papers in Aging. Recurrent topics in Isaac B. Hilton's work include CRISPR and Genetic Engineering (15 papers), Pluripotent Stem Cells Research (6 papers) and Advanced biosensing and bioanalysis techniques (5 papers). Isaac B. Hilton is often cited by papers focused on CRISPR and Genetic Engineering (15 papers), Pluripotent Stem Cells Research (6 papers) and Advanced biosensing and bioanalysis techniques (5 papers). Isaac B. Hilton collaborates with scholars based in United States, China and Netherlands. Isaac B. Hilton's co-authors include Charles A. Gersbach, Pratiksha I. Thakore, Timothy E. Reddy, Gregory E. Crawford, Anthony D’Ippolito, Christopher M. Vockley, Joshua B. Black, Ami M. Kabadi, David G. Ousterout and Jacob Goell and has published in prestigious journals such as Journal of the American Chemical Society, Nucleic Acids Research and Advanced Materials.

In The Last Decade

Isaac B. Hilton

23 papers receiving 3.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers

2015 1.3k citations Isaac B. Hilton, Anthony D’Ippolito et al. Nature Biotechnology profile →
Engineering the next generation of cell-based therapeutics

2022 249 citations Caleb J. Bashor, Isaac B. Hilton et al. Nature Reviews Drug Discovery profile →

Peers

Countries citing papers authored by Isaac B. Hilton

Since Specialization

Citations

This map shows the geographic impact of Isaac B. Hilton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Isaac B. Hilton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Isaac B. Hilton more than expected).

Fields of papers citing papers by Isaac B. Hilton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Isaac B. Hilton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Isaac B. Hilton. The network helps show where Isaac B. Hilton may publish in the future.

Co-authorship network of co-authors of Isaac B. Hilton

This figure shows the co-authorship network connecting the top 25 collaborators of Isaac B. Hilton. A scholar is included among the top collaborators of Isaac B. Hilton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Isaac B. Hilton. Isaac B. Hilton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Biomolecular condensation of human IDRs initiates endogenous transcription via intrachromosomal looping or high-density promoter localization 2025 ·Nucleic Acids Research ·Jing Li, Shizhe Liu, Sung Hwan Kim, Jacob Goell, (unknown), (unknown), J. Alex, Barun Mahata, (unknown), (unknown), Jeong Hyun Ahn, (unknown), (unknown), Yuhao Zhou, (unknown), Michael Diehl, Gang Greg Wang, Anna‐Karin Gustavsson, Douglas H. Phanstiel, Isaac B. Hilton	1
2	Characterization of Rationally Designed CRISPR/Cas9-Based DNA Methyltransferases with Distinct Methyltransferase and Gene Silencing Activities in Human Cell Lines and Primary Human T Cells 2025 ·ACS Synthetic Biology ·(unknown), (unknown), J. Alex, (unknown), Daniel Reed, Sung Hwan Kim, (unknown), Tomoki Nishiguchi, (unknown), Andrew R. DiNardo, Isaac B. Hilton	0
3	Persistent tailoring of MSC activation through genetic priming 2024 ·Molecular Therapy — Methods & Clinical Development ·(unknown), (unknown), Daniel Brenner, (unknown), Tomoki Nishiguchi, Abhimanyu Abhimanyu, (unknown), Barun Mahata, Omid Veiseh, Pamela L. Wenzel, Andrew R. DiNardo, Isaac B. Hilton, Michael Diehl	0
4	Lipid Deposition Profiles Influence Foreign Body Responses 2023 ·Advanced Materials ·(unknown), Maria Jarvis, Tanguy Terlier, Jacob Goell, Sudip Mukherjee, (unknown), Taylor Wilson, (unknown), (unknown), J. Jack Lee, (unknown), (unknown), Matthias A. Oberli, Brian W. Hanak, Michael Diehl, Isaac B. Hilton, Omid Veiseh	16
5	Compact engineered human mechanosensitive transactivation modules enable potent and versatile synthetic transcriptional control 2023 ·Nature Methods ·Barun Mahata, (unknown), Daniel Brenner, (unknown), Jing Li, Jacob Goell, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Daniel Reed, Sung Hwan Kim, Isaac B. Hilton	21
6	Temporal analysis suggests a reciprocal relationship between 3D chromatin structure and transcription 2022 ·Cell Reports ·(unknown), Eric S. Davis, (unknown), (unknown), (unknown), Ivana Yoseli Quiroga, (unknown), (unknown), Isaac B. Hilton, Hyejung Won, Michael I. Love, Douglas H. Phanstiel	21
7	Harnessing CRISPR-Cas9 for Epigenetic Engineering 2022 ·Methods in molecular biology ·(unknown), Isaac B. Hilton	5
8	Engineering the next generation of cell-based therapeutics breakdown → 2022 ·Nature Reviews Drug Discovery ·Caleb J. Bashor, Isaac B. Hilton, Hozefa S. Bandukwala, Devyn M. Smith, Omid Veiseh	249
9	Quantification of Genome Editing and Transcriptional Control Capabilities Reveals Hierarchies among Diverse CRISPR/Cas Systems in Human Cells 2022 ·ACS Synthetic Biology ·(unknown), Jing Li, (unknown), Shizhe Liu, (unknown), Isaac B. Hilton	15
10	Programmable human histone phosphorylation and gene activation using a CRISPR/Cas9-based chromatin kinase 2021 ·Nature Communications ·Jing Li, Barun Mahata, (unknown), Jacob Goell, (unknown), (unknown), Isaac B. Hilton	55
11	Reversing Post-Infectious Epigenetic-Mediated Immune Suppression 2021 ·Frontiers in Immunology ·Abhimanyu Abhimanyu, (unknown), (unknown), Tomoki Nishiguchi, (unknown), Isaac B. Hilton, Larry S. Schlesinger, Andrew R. DiNardo	23
12	CRISPR/Cas-Based Epigenome Editing: Advances, Applications, and Clinical Utility 2021 ·Trends in biotechnology ·Jacob Goell, Isaac B. Hilton	77
13	Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects 2020 ·Science Advances ·(unknown), Ning Ding, Yidi Sun, Tanglong Yuan, Jing Li, (unknown), Lizhong Liu, Jie Yang, Qian Wang, Anatoly B. Kolomeisky, Isaac B. Hilton, Erwei Zuo, Xue Gao	64
14	CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome 2017 ·Nature Biotechnology ·Tyler S. Klann, Joshua B. Black, Malathi Chellappan, Alexias Safi, Lingyun Song, Isaac B. Hilton, Gregory E. Crawford, Timothy E. Reddy, Charles A. Gersbach	285
15	Editing the epigenome: technologies for programmable transcription and epigenetic modulation 2016 ·Nature Methods ·Pratiksha I. Thakore, Joshua B. Black, Isaac B. Hilton, Charles A. Gersbach	319
16	Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers breakdown → 2015 ·Nature Biotechnology ·Isaac B. Hilton, Anthony D’Ippolito, Christopher M. Vockley, Pratiksha I. Thakore, Gregory E. Crawford, Timothy E. Reddy, Charles A. Gersbach	1343
17	Enabling functional genomics with genome engineering 2015 ·Genome Research ·Isaac B. Hilton, Charles A. Gersbach	81
18	Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector 2014 ·Nucleic Acids Research ·Ami M. Kabadi, David G. Ousterout, Isaac B. Hilton, Charles A. Gersbach	264
19	mTOR Inhibitors Block Kaposi Sarcoma Growth by Inhibiting Essential Autocrine Growth Factors and Tumor Angiogenesis 2013 ·Cancer Research ·Debasmita Roy, Sang‐Hoon Sin, Amy Lucas, Raman Venkataramanan, Ling Wang, Anthony B. Eason, (unknown), Isaac B. Hilton, Kristen M. Tamburro, Blossom Damania, Dirk P. Dittmer	58
20	Distinct p53, p53:LANA, and LANA Complexes in Kaposi's Sarcoma-Associated Herpesvirus Lymphomas 2010 ·Journal of Virology ·(unknown), Isaac B. Hilton, Michelle R. Staudt, Christin E. Burd, Dirk P. Dittmer	56

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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