Irene Chau

2.7k total citations
21 papers, 917 citations indexed

About

Irene Chau is a scholar working on Molecular Biology, Infectious Diseases and Oncology. According to data from OpenAlex, Irene Chau has authored 21 papers receiving a total of 917 indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 2 papers in Infectious Diseases and 2 papers in Oncology. Recurrent topics in Irene Chau's work include Cancer-related gene regulation (8 papers), Epigenetics and DNA Methylation (7 papers) and RNA and protein synthesis mechanisms (6 papers). Irene Chau is often cited by papers focused on Cancer-related gene regulation (8 papers), Epigenetics and DNA Methylation (7 papers) and RNA and protein synthesis mechanisms (6 papers). Irene Chau collaborates with scholars based in Canada, United States and Czechia. Irene Chau's co-authors include Masoud Vedadi, Guillermo Senisterra, Abdellah Allali‐Hassani, C.H. Arrowsmith, Matthieu Schapira, Alena Siarheyeva, Jian Jin, Peter J. Brown, Fengling Li and Taraneh Hajian and has published in prestigious journals such as Journal of Biological Chemistry, Biochemical Journal and Journal of Medicinal Chemistry.

In The Last Decade

Irene Chau

20 papers receiving 904 citations

Peers

Irene Chau

PARAS

EPIDE

Kristofor J. Webb United States

A. Krupa India

Ashley Hutchinson Canada

László Dobson Hungary

Paula M. Dulski United States

Ghislain G. Cabal Germany

Robin E. Stanley United States

Sebastian K. Wandinger Germany

Sergey Tcherniuk France

Xiaokai Li China

Kristofor J. Webb United States

Irene Chau

1.1k ×1.7

104 ×0.9

97 ×1.1

31 ×0.4

PARAS

85 ×1.2

EPIDE

Citations per year, relative to Irene Chau Irene Chau (= 1×) peers Kristofor J. Webb

Countries citing papers authored by Irene Chau

Since Specialization

Citations

This map shows the geographic impact of Irene Chau's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Irene Chau with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Irene Chau more than expected).

Fields of papers citing papers by Irene Chau

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Irene Chau. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Irene Chau. The network helps show where Irene Chau may publish in the future.

Co-authorship network of co-authors of Irene Chau

This figure shows the co-authorship network connecting the top 25 collaborators of Irene Chau. A scholar is included among the top collaborators of Irene Chau based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Irene Chau. Irene Chau is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kimani, Serah, Martin P. Schwalm, H. Holzmann, et al.. (2025). Discovery of an exquisitely selective WDR5 chemical probe accelerated by a high-quality DEL–ML Hit. RSC Chemical Biology. 6(10). 1585–1594. 1 indexed citations

Li, Fengling, Hong Zeng, Irene Chau, et al.. (2025). ATPase activity profiling of three human DExD/H-box RNA helicases. SLAS DISCOVERY. 32. 100229–100229.

Eguida, Merveille, Guillaume Bret, Fengling Li, et al.. (2024). Subpocket Similarity-Based Hit Identification for Challenging Targets: Application to the WDR Domain of LRRK2. Journal of Chemical Information and Modeling. 64(13). 5344–5355. 4 indexed citations

Xiong, Yan, Holger Greschik, C. Johansson, et al.. (2024). Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor. Journal of Medicinal Chemistry. 67(7). 5837–5853. 2 indexed citations

Kimani, Serah, Sumera Perveen, Hong Zeng, et al.. (2023). The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition. Communications Biology. 6(1). 1272–1272. 12 indexed citations

Li, Fengling, Pegah Ghiabi, Taraneh Hajian, et al.. (2023). SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses. Biochimica et Biophysica Acta (BBA) - General Subjects. 1867(4). 130319–130319. 15 indexed citations

Santhakumar, Vijayaratnam, Irene Chau, Fengling Li, et al.. (2023). Development of selective class I protein arginine methyltransferase inhibitors through fragment-based drug design approach. European Journal of Medicinal Chemistry. 260. 115713–115713. 8 indexed citations

Feller, Christian, Abdellah Allali‐Hassani, Magdalena M. Szewczyk, et al.. (2022). Enzymatic nucleosome acetylation selectively affects activity of histone methyltransferases in vitro. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1865(5). 194845–194845. 5 indexed citations

Klíma, Martin, Aliakbar Khalili Yazdi, Fengling Li, et al.. (2022). Crystal structure of SARS‐CoV‐2 nsp10–nsp16 in complex with small molecule inhibitors, SS148 and WZ16. Protein Science. 31(9). e4395–e4395. 22 indexed citations

10.

Devkota, Kanchan, Matthieu Schapira, Sumera Perveen, et al.. (2021). Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors. SLAS DISCOVERY. 26(9). 1200–1211. 55 indexed citations

11.

Šála, Michal, Fengling Li, Jindřich Fanfrlík, et al.. (2021). The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors. ACS Infectious Diseases. 7(8). 2214–2220. 69 indexed citations

12.

Shen, Yudao, Fengling Li, Magdalena M. Szewczyk, et al.. (2020). Discovery of a First-in-Class Protein Arginine Methyltransferase 6 (PRMT6) Covalent Inhibitor. Journal of Medicinal Chemistry. 63(10). 5477–5487. 29 indexed citations

13.

Senisterra, Guillermo, Peter J. Brown, Irene Chau, et al.. (2020). Discovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a. Figshare. 1 indexed citations

14.

Senisterra, Guillermo, Hugh Zhu, Xiao Luo, et al.. (2018). Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain. SLAS DISCOVERY. 23(9). 930–940. 28 indexed citations

15.

Eram, Mohammad S., Ekaterina Kuznetsova, Fengling Li, et al.. (2015). Kinetic characterization of human histone H3 lysine 36 methyltransferases, ASH1L and SETD2. Biochimica et Biophysica Acta (BBA) - General Subjects. 1850(9). 1842–1848. 35 indexed citations

16.

Eram, Mohammad S., Evelyne Lima‐Fernandes, Alena Siarheyeva, et al.. (2014). Trimethylation of Histone H3 Lysine 36 by Human Methyltransferase PRDM9 Protein. Journal of Biological Chemistry. 289(17). 12177–12188. 87 indexed citations

17.

Senisterra, Guillermo, Irene Chau, & Masoud Vedadi. (2011). Thermal Denaturation Assays in Chemical Biology. Assay and Drug Development Technologies. 10(2). 128–136. 108 indexed citations

18.

Wernimont, Amy K., J.D. Artz, P.J. Finerty, et al.. (2010). Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium. Nature Structural & Molecular Biology. 17(5). 596–601. 183 indexed citations

19.

Allali‐Hassani, Abdellah, Gregory A. Wasney, Irene Chau, et al.. (2009). A survey of proteins encoded by non-synonymous single nucleotide polymorphisms reveals a significant fraction with altered stability and activity. Biochemical Journal. 424(1). 15–26. 39 indexed citations

20.

Liu, Feng, Xin Chen, Abdellah Allali‐Hassani, et al.. (2009). Discovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a. Journal of Medicinal Chemistry. 52(24). 7950–7953. 189 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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