Ignazio Caruana

3.6k total citations · 1 hit paper
35 papers, 1.8k citations indexed

About

Ignazio Caruana is a scholar working on Oncology, Immunology and Molecular Biology. According to data from OpenAlex, Ignazio Caruana has authored 35 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 26 papers in Oncology, 22 papers in Immunology and 9 papers in Molecular Biology. Recurrent topics in Ignazio Caruana's work include CAR-T cell therapy research (23 papers), Immune Cell Function and Interaction (12 papers) and Immunotherapy and Immune Responses (9 papers). Ignazio Caruana is often cited by papers focused on CAR-T cell therapy research (23 papers), Immune Cell Function and Interaction (12 papers) and Immunotherapy and Immune Responses (9 papers). Ignazio Caruana collaborates with scholars based in Italy, Germany and United States. Ignazio Caruana's co-authors include Gianpietro Dotti, Barbara Savoldo, Valentina Hoyos, Gerrit Weber, Hao Liu, Michael Ittmann, Eugene S. Kim, Philippe Marchetti, Iulia Diaconu and Franco Locatelli and has published in prestigious journals such as Journal of Clinical Investigation, Nature Medicine and Nature Communications.

In The Last Decade

Ignazio Caruana

33 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes

2015 642 citations Ignazio Caruana, Barbara Savoldo et al. Nature Medicine profile →

Peers

Ignazio Caruana

ONCOL

IMMUN

GENET

Selene Nuñez-Cruz United States

Biagio De Angelis Italy

Mark B. Leick United States

Jamie R. Wagner United States

Robert C. Sterner United States

Valentina Hoyos United States

Brenda Aguilar United States

Rebecca C. Larson United States

Liza B. John Australia

Elena Sotillo United States

Selene Nuñez-Cruz United States

Ignazio Caruana

1.1k ×0.8

ONCOL

891 ×1.3

IMMUN

584 ×1.1

322 ×0.6

GENET

365 ×0.7

Citations per year, relative to Ignazio Caruana Ignazio Caruana (= 1×) peers Selene Nuñez-Cruz

Countries citing papers authored by Ignazio Caruana

Since Specialization

Citations

This map shows the geographic impact of Ignazio Caruana's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ignazio Caruana with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ignazio Caruana more than expected).

Fields of papers citing papers by Ignazio Caruana

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ignazio Caruana. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ignazio Caruana. The network helps show where Ignazio Caruana may publish in the future.

Co-authorship network of co-authors of Ignazio Caruana

This figure shows the co-authorship network connecting the top 25 collaborators of Ignazio Caruana. A scholar is included among the top collaborators of Ignazio Caruana based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ignazio Caruana. Ignazio Caruana is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Carlomagno, Simona, Michela Falco, Claudia Cantoni, et al.. (2025). CD94-driven in vitro expansion of highly functional adaptive NKG2C+ NKG2A- CD57+ NK cells from CMV+ healthy donors. Frontiers in Immunology. 16. 1481745–1481745. 2 indexed citations

Dirks, Johannes, Christine Hofmann, Christian Klemann, et al.. (2024). Disease-specific T cell receptors maintain pathogenic T helper cell responses in postinfectious Lyme arthritis. Journal of Clinical Investigation. 134(17). 4 indexed citations

Caruana, Ignazio, et al.. (2023). Transdermal carbon monoxide delivery. Journal of Controlled Release. 357. 299–308. 8 indexed citations

Schlegel, Paul‐Gerhardt, et al.. (2023). Exploiting autophagy balance in T and NK cells as a new strategy to implement adoptive cell therapies. Molecular Cancer. 22(1). 201–201. 10 indexed citations

Buechner, Jochen, Ignazio Caruana, Annette Künkele, et al.. (2022). Chimeric Antigen Receptor T-Cell Therapy in Paediatric B-Cell Precursor Acute Lymphoblastic Leukaemia: Curative Treatment Option or Bridge to Transplant?. Frontiers in Pediatrics. 9. 784024–784024. 16 indexed citations

Weber, Gerrit, Luisa Strocchio, Francesca Del Bufalo, et al.. (2021). Identification of New Soluble Factors Correlated With the Development of Graft Failure After Haploidentical Hematopoietic Stem Cell Transplantation. Frontiers in Immunology. 11. 613644–613644. 8 indexed citations

Mokhtari, Zeinab, Theresa Schneider, Anna‐Leena Sirén, et al.. (2021). Cytotoxic effects and tolerability of gemcitabine and axitinib in a xenograft model for c-myc amplified medulloblastoma. Scientific Reports. 11(1). 14062–14062. 15 indexed citations

Merli, Pietro, Ignazio Caruana, Rita De Vito, et al.. (2019). Role of interferon-γ in immune-mediated graft failure after allogeneic hematopoietic stem cell transplantation. Haematologica. 104(11). 2314–2323. 49 indexed citations

Polito, Vinicia Assunta, Gerrit Weber, Francesca Del Bufalo, et al.. (2019). Universal Ready-to-Use Immunotherapeutic Approach for the Treatment of Cancer: Expanded and Activated Polyclonal γδ Memory T Cells. Frontiers in Immunology. 10. 2717–2717. 32 indexed citations

10.

D’Acunzo, Pasquale, Flavie Strappazzon, Ignazio Caruana, et al.. (2019). Reversible induction of mitophagy by an optogenetic bimodular system. Nature Communications. 10(1). 1533–1533. 32 indexed citations

11.

Orlando, Domenico, Evelina Miele, Biagio De Angelis, et al.. (2018). Adoptive Immunotherapy Using PRAME-Specific T Cells in Medulloblastoma. Cancer Research. 78(12). 3337–3349. 56 indexed citations

12.

Quintarelli, Concetta, Domenico Orlando, Iolanda Boffa, et al.. (2018). Choice of costimulatory domains and of cytokines determines CAR T-cell activity in neuroblastoma. OncoImmunology. 7(6). e1433518–e1433518. 106 indexed citations

13.

Caruana, Ignazio, Luca Simula, Franco Locatelli, & Silvia Campello. (2018). T lymphocytes against solid malignancies: winning ways to defeat tumours. SHILAP Revista de lepidopterología. 2(8). 200–212. 21 indexed citations

14.

Bocca, Paola, Emma Di Carlo, Ignazio Caruana, et al.. (2017). Bevacizumab-mediated tumor vasculature remodelling improves tumor infiltration and antitumor efficacy of GD2-CAR T cells in a human neuroblastoma preclinical model. OncoImmunology. 7(1). e1378843–e1378843. 95 indexed citations

15.

Caruana, Ignazio, et al.. (2015). K562-Derived Whole-Cell Vaccine Enhances Antitumor Responses of CAR-Redirected Virus-Specific Cytotoxic T Lymphocytes In Vivo. Clinical Cancer Research. 21(13). 2952–2962. 32 indexed citations

16.

Caruana, Ignazio, Barbara Savoldo, Valentina Hoyos, et al.. (2015). Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes. Nature Medicine. 21(5). 524–529. 642 indexed citations breakdown →

17.

Nishio, Nobuhiro, Iulia Diaconu, Hao Liu, et al.. (2014). Armed Oncolytic Virus Enhances Immune Functions of Chimeric Antigen Receptor–Modified T Cells in Solid Tumors. Cancer Research. 74(18). 5195–5205. 272 indexed citations

18.

Caruana, Ignazio, Iulia Diaconu, & Gianpietro Dotti. (2014). From Monoclonal Antibodies to Chimeric Antigen Receptors for the Treatment of Human Malignancies. Seminars in Oncology. 41(5). 661–666. 33 indexed citations

19.

Weber, Gerrit, Ignazio Caruana, Rayne H. Rouce, et al.. (2013). Generation of Tumor Antigen-Specific T Cell Lines from Pediatric Patients with Acute Lymphoblastic Leukemia—Implications for Immunotherapy. Clinical Cancer Research. 19(18). 5079–5091. 55 indexed citations

20.

Geldres, Claudia, Barbara Savoldo, Valentina Hoyos, et al.. (2013). T Lymphocytes Redirected against the Chondroitin Sulfate Proteoglycan-4 Control the Growth of Multiple Solid Tumors both In Vitro and In Vivo. Clinical Cancer Research. 20(4). 962–971. 80 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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