H.T. Claude Chan

4.9k total citations
54 papers, 3.5k citations indexed

About

H.T. Claude Chan is a scholar working on Radiology, Nuclear Medicine and Imaging, Immunology and Oncology. According to data from OpenAlex, H.T. Claude Chan has authored 54 papers receiving a total of 3.5k indexed citations (citations by other indexed papers that have themselves been cited), including 41 papers in Radiology, Nuclear Medicine and Imaging, 33 papers in Immunology and 19 papers in Oncology. Recurrent topics in H.T. Claude Chan's work include Monoclonal and Polyclonal Antibodies Research (40 papers), T-cell and B-cell Immunology (18 papers) and CAR-T cell therapy research (13 papers). H.T. Claude Chan is often cited by papers focused on Monoclonal and Polyclonal Antibodies Research (40 papers), T-cell and B-cell Immunology (18 papers) and CAR-T cell therapy research (13 papers). H.T. Claude Chan collaborates with scholars based in United Kingdom, Netherlands and United States. H.T. Claude Chan's co-authors include Martin J. Glennie, Ruth R. French, Mark S. Cragg, Stephen A. Beers, Alison L. Tutt, Peter Johnson, C. Ian Mockridge, Sean H. Lim, Kerry L. Cox and J. Sjef Verbeek and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

H.T. Claude Chan

53 papers receiving 3.4k citations

Peers

Countries citing papers authored by H.T. Claude Chan

Since Specialization

Citations

This map shows the geographic impact of H.T. Claude Chan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by H.T. Claude Chan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites H.T. Claude Chan more than expected).

Fields of papers citing papers by H.T. Claude Chan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by H.T. Claude Chan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by H.T. Claude Chan. The network helps show where H.T. Claude Chan may publish in the future.

Co-authorship network of co-authors of H.T. Claude Chan

This figure shows the co-authorship network connecting the top 25 collaborators of H.T. Claude Chan. A scholar is included among the top collaborators of H.T. Claude Chan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with H.T. Claude Chan. H.T. Claude Chan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Structure-guided disulfide engineering restricts antibody conformation to elicit TNFR agonism 2025 ·Nature Communications ·(unknown), (unknown), H.T. Claude Chan, Tatyana Inzhelevskaya, C. Ian Mockridge, Christine A. Penfold, Patrick J. Duriez, Christian M. Orr, Julie Herniman, (unknown), Jonathan W. Essex, Mark S. Cragg, Ivo Tews	1
2	Reducing affinity as a strategy to boost immunomodulatory antibody agonism 2023 ·Nature ·Xiaojie Yu, Christian M. Orr, H.T. Claude Chan, Sonya James, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Kerry L. Cox, Jonathan W. Essex, Ivo Tews, Martin J. Glennie, Mark S. Cragg	71
3	Fcγ receptor binding is required for maximal immunostimulation by CD70-Fc 2023 ·Frontiers in Immunology ·(unknown), Joel D. Allen, Sarah L. Buchan, Jinny Kim, H.T. Claude Chan, C. Ian Mockridge, Patrick J. Duriez, Anne Rogel, Max Crispin, Aymen Al‐Shamkhani	1
4	Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility 2022 ·Science Immunology ·Christian M. Orr, (unknown), Xiaojie Yu, H.T. Claude Chan, Yunyun Gao, Patrick J. Duriez, Steven G. Booth, (unknown), Tatyana Inzhelevskaya, (unknown), Christine A. Penfold, Armin Wagner, Martin J. Glennie, Ann L. White, Jonathan W. Essex, Arwen R. Pearson, Mark S. Cragg, Ivo Tews	30
5	FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms 2022 ·Cell Reports ·(unknown), Ali Roghanian, Robert Oldham, H.T. Claude Chan, Christine A. Penfold, Hyung J. Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Kerry L. Cox, Yury D. Bogdanov, Sonya James, Alison L. Tutt, (unknown), Peter T. Morley, Lekh N. Dahal, Ingrid Teige, Björn Frendéus, Stephen A. Beers, Mark S. Cragg	16
6	Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering 2022 ·Communications Biology ·(unknown), (unknown), (unknown), H.T. Claude Chan, Michael J. Marshall, (unknown), Christine A. Penfold, Tatyana Inzhelevskaya, C. Ian Mockridge, Diego Alvarado, Ivo Tews, Tibor Keler, Stephen A. Beers, Mark S. Cragg, Sean H. Lim	12
7	TNF receptor agonists induce distinct receptor clusters to mediate differential agonistic activity 2021 ·Communications Biology ·Xiaojie Yu, Sonya James, James H. Felce, Blanka Kellermayer, David A. Johnston, H.T. Claude Chan, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Yasunori Watanabe, Max Crispin, Ruth R. French, Patrick J. Duriez, Leon Douglas, Martin J. Glennie, Mark S. Cragg	35
8	Isotype Switching Converts Anti-CD40 Antagonism to Agonism to Elicit Potent Antitumor Activity 2020 ·Cancer Cell ·Xiaojie Yu, H.T. Claude Chan, (unknown), Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Ruth R. French, Patrick J. Duriez, Leon Douglas, (unknown), J. Sjef Verbeek, Ann L. White, Ivo Tews, Martin J. Glennie, Mark S. Cragg	48
9	Detection of Experimental and Clinical Immune Complexes by Measuring SHIP-1 Recruitment to the Inhibitory FcγRIIB 2018 ·The Journal of Immunology ·(unknown), Robert Oldham, Alison L. Tutt, Patrick J. Duriez, H.T. Claude Chan, Brock F. Binkowski, Chad Zimprich, Dun Li, Philip G. Hargreaves, Mei Cong, Venkat Reddy, Maria Leandro, Geraldine Cambridge, Anja Lux, Falk Nimmerjahn, Mark S. Cragg	6
10	Antibody Distance from the Cell Membrane Regulates Antibody Effector Mechanisms 2017 ·The Journal of Immunology ·Kirstie L.S. Cleary, H.T. Claude Chan, (unknown), Martin J. Glennie, Mark S. Cragg	92
11	FcγRΙΙB controls the potency of agonistic anti-TNFR mAbs 2013 ·Cancer Immunology Immunotherapy ·Ann L. White, H.T. Claude Chan, Ruth R. French, Stephen A. Beers, Mark S. Cragg, Peter Johnson, Martin J. Glennie	34
12	Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies 2011 ·Blood ·Waleed Alduaij, Andrei Ivanov, Jamie Honeychurch, Eleanor J. Cheadle, Sandeep Potluri, Sean H. Lim, Kazuyuki Shimada, H.T. Claude Chan, Andrew Tutt, Stephen A. Beers, Martin J. Glennie, Mark S. Cragg, Tim Illidge	222
13	Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection 2010 ·Blood ·Stephen A. Beers, Ruth R. French, H.T. Claude Chan, Sean H. Lim, (unknown), (unknown), (unknown), Sandra V. Dixon, Hyungjin Kim, Kerry L. Cox, Jonathan P. Kerr, David A. Johnston, Peter Johnson, J. Sjef Verbeek, Martin J. Glennie, Mark S. Cragg	241
14	CD20 as a Target for Therapeutic Type I and II Monoclonal Antibodies 2010 ·Seminars in Hematology ·Stephen A. Beers, H.T. Claude Chan, Ruth R. French, Mark S. Cragg, Martin J. Glennie	167
15	Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells 2009 ·Journal of Clinical Investigation ·А. В. Иванов, Stephen A. Beers, Claire A. Walshe, Jamie Honeychurch, Waleed Alduaij, Kerry L. Cox, Kathleen N. Potter, Stephen Murray, H.T. Claude Chan, Tetyana Klymenko, Jekaterina Ērenpreisa, Martin J. Glennie, Tim Illidge, Mark S. Cragg	142
16	Induction of Cytosolic Calcium Flux by CD20 Is Dependent upon B Cell Antigen Receptor Signaling 2008 ·Journal of Biological Chemistry ·Claire A. Walshe, Stephen A. Beers, Ruth R. French, H.T. Claude Chan, Peter Johnson, Graham Packham, Martin J. Glennie, Mark S. Cragg	117
17	Immunotherapy with Antibody-Targeted HLA Class I Complexes: Results of in vivo Tumour Cell Killing and Therapeutic Vaccination 2007 ·Tumor Biology ·Philip Savage, Julian Dyson, (unknown), (unknown), Ben C. King, H.T. Claude Chan, Linda D. Barber, Agamemnon A. Epenetos, Graham S. Ogg, Andrew McMichael, Martin J. Glennie, Ruth R. French	4
18	Expression and costimulatory effects of the TNF receptor superfamily members CD134 (OX40) and CD137 (4-1BB), and their role in the generation of anti-tumor immune responses 2002 ·European Journal of Immunology ·Vadim Y. Taraban, Tania F. Rowley, Lyn M. O’Brien, H.T. Claude Chan, Linsey E. Haswell, (unknown), Alison L. Tutt, Martin J. Glennie, Aymen Al‐Shamkhani	120
19	CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help 1999 ·Nature Medicine ·Ruth R. French, H.T. Claude Chan, Alison L. Tutt, Martin J. Glennie	348
20	The mechanism of inhibition by EDTA and EGTA of methanol oxidation by methylotrophic bacteria 1992 ·FEMS Microbiology Letters ·H.T. Claude Chan	16

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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