Hitoshi Akedo

4.0k total citations · 1 hit paper
96 papers, 3.5k citations indexed

About

Hitoshi Akedo is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Hitoshi Akedo has authored 96 papers receiving a total of 3.5k indexed citations (citations by other indexed papers that have themselves been cited), including 53 papers in Molecular Biology, 27 papers in Oncology and 15 papers in Cancer Research. Recurrent topics in Hitoshi Akedo's work include Liver physiology and pathology (8 papers), Cancer Research and Treatments (8 papers) and Cancer Cells and Metastasis (8 papers). Hitoshi Akedo is often cited by papers focused on Liver physiology and pathology (8 papers), Cancer Research and Treatments (8 papers) and Cancer Cells and Metastasis (8 papers). Hitoshi Akedo collaborates with scholars based in Japan, Belgium and United States. Hitoshi Akedo's co-authors include Mutsuko Mukai, Kiyoko Shinkai, Kiyoko Yoshioka, Kazuyuki Itoh, Masayoshi Uehata, Toshimasa Ishizaki, Shuh Narumiya, Teruo Iwasaki, Masaharu Tatsuta and Hiroyuki Nakamura and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Medicine.

In The Last Decade

Hitoshi Akedo

95 papers receiving 3.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

An essential part for Rho–associated kinase in the transcellular invasion of tumor cells

1999 536 citations Kazuyuki Itoh, Kiyoko Yoshioka et al. Nature Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Hitoshi Akedo Japan	31	2.1k	793	641	582	549	96	3.5k
Masayoshi Namba Japan	35	2.8k 1.3×	1.1k 1.4×	402 0.6×	533 0.9×	430 0.8×	186	4.8k
Hisao Kato Japan	34	1.9k 0.9×	278 0.4×	655 1.0×	384 0.7×	385 0.7×	135	4.6k
Julián Gómez-Cambronero United States	35	2.1k 1.0×	546 0.7×	571 0.9×	400 0.7×	1.0k 1.8×	113	3.6k
Niels Peter Hundahl Møller Denmark	29	4.1k 1.9×	732 0.9×	531 0.8×	565 1.0×	1.6k 2.8×	57	5.2k
Marie‐Christine Rio France	38	2.2k 1.0×	1.4k 1.7×	447 0.7×	1.6k 2.8×	721 1.3×	68	4.3k
Katsuhiko Enomoto Japan	33	2.0k 0.9×	553 0.7×	293 0.5×	499 0.9×	280 0.5×	103	3.8k
Renate Hofer-Warbinek Austria	24	1.8k 0.9×	554 0.7×	327 0.5×	627 1.1×	859 1.6×	35	3.1k
Timothy Clair United States	41	3.2k 1.5×	989 1.2×	762 1.2×	355 0.6×	379 0.7×	87	4.4k
Joseph Fargnoli United States	34	2.3k 1.1×	750 0.9×	372 0.6×	627 1.1×	826 1.5×	56	3.9k
Fernando Vidal‐Vanaclocha Spain	34	1.6k 0.7×	965 1.2×	211 0.3×	487 0.8×	942 1.7×	72	3.1k

Countries citing papers authored by Hitoshi Akedo

Since Specialization

Citations

This map shows the geographic impact of Hitoshi Akedo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hitoshi Akedo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hitoshi Akedo more than expected).

Fields of papers citing papers by Hitoshi Akedo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hitoshi Akedo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hitoshi Akedo. The network helps show where Hitoshi Akedo may publish in the future.

Co-authorship network of co-authors of Hitoshi Akedo

This figure shows the co-authorship network connecting the top 25 collaborators of Hitoshi Akedo. A scholar is included among the top collaborators of Hitoshi Akedo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hitoshi Akedo. Hitoshi Akedo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Yamada, N, S. Niwa, Tohru Tsujimura, et al.. (2002). Interleukin-18 and interleukin-12 synergistically inhibit osteoclastic bone-resorbing activity. Bone. 30(6). 901–908. 61 indexed citations

Iwasaki, Teruo, Mutsuko Mukai, Tohru Tsujimura, et al.. (2002). Ipriflavone inhibits osteolytic bone metastasis of human breast cancer cells in a nude mouse model. International Journal of Cancer. 100(4). 381–387. 17 indexed citations

Tatsuta, Masaharu, Hiroyasu Iishi, Miyako Baba, et al.. (2001). Induction by bombesin of peritoneal metastasis of gastric cancers induced by N -methyl- N ?-nitro- N -nitrosoguanidine in Wistar rats. Gastric Cancer. 4(1). 14–19. 4 indexed citations

Komatsu, K, S Ishiguro, Noriko Suzuki, et al.. (2000). Increased expression of S100A6 at the invading fronts of the primary lesion and liver metastasis in patients with colorectal adenocarcinoma. British Journal of Cancer. 83(6). 769–774. 73 indexed citations

Imamura, Fumio, Mutsuko Mukai, Masako Ayaki, et al.. (1999). Involvement of small GTPases Rho and Rac in the invasion of rat ascites hepatoma cells. Clinical & Experimental Metastasis. 17(2). 141–148. 29 indexed citations

Itoh, Kazuyuki, Kiyoko Yoshioka, Hitoshi Akedo, et al.. (1999). An essential part for Rho–associated kinase in the transcellular invasion of tumor cells. Nature Medicine. 5(2). 221–225. 536 indexed citations breakdown →

Matsuda, Hikaru, et al.. (1998). [Reoperation after the Fontan operation in single ventricle and tricuspid atresia].. PubMed. 99(2). 84–9. 1 indexed citations

Yamamura, Hisako, Hideki Yoshikawa, Masaharu Tatsuta, Hitoshi Akedo, & Katsuhito Takahashi. (1998). Expression of the smooth muscle calponin gene in human osteosarcoma and its possible association with prognosis. International Journal of Cancer. 79(3). 245–250. 43 indexed citations

Nakamori, Shoji, Hirotaka Okamoto, Toshiyuki Kusama, et al.. (1997). Increased endothelial cell retraction and tumor cell invasion by soluble factors derived from pancreatic cancer cells. Annals of Surgical Oncology. 4(4). 361–368. 12 indexed citations

10.

Shinkai, Kiyoko, Hitoshi Akedo, Mutsuko Mukai, et al.. (1996). Inhibition of in vitro Tumor Cell Invasion by Ginsenoside Rg₃. Japanese Journal of Cancer Research. 87(4). 357–362. 122 indexed citations

11.

Yoshioka, Kiyoko, Fumio Imamura, Kiyoko Shinkai, et al.. (1995). Participation of rhop21 in serum‐dependent invasion by rat ascites hepatoma cells. FEBS Letters. 372(1). 25–28. 20 indexed citations

12.

Kusama, Toshiyuki, Shoji Nakamori, Hiroaki Ohigashi, et al.. (1995). Enhancement of in vitro tumor—cell transcellular migration by tumor—cell—secreted endothelial—cell—retraction factor. International Journal of Cancer. 63(1). 112–118. 23 indexed citations

13.

Yamamoto, Takashi, Nobuyuki Terada, Yasuko Nishizawa, et al.. (1994). Effects of NG-nitro-l-arginine and/or l-arginine on experimental pulmonary metastasis in mice. Cancer Letters. 87(1). 115–120. 23 indexed citations

14.

Yoshioka, Kiyoko, Mutsuko Mukai, Kiyoko Shinkai, & Hitoshi Akedo. (1993). Retraction of cultured endothelial cell monolayer by human breast cancer cells, MCF‐7.. Cell Biology International. 17(12). 1053–1063. 6 indexed citations

15.

Imamura, Fumio, Takeshi Horai, Mutsuko Mukai, et al.. (1993). Induction of in Vitro Tumor Cell Invasion of Cellular Monolayers by Lysophosphatidic Acid or Phospholipase D. Biochemical and Biophysical Research Communications. 193(2). 497–503. 167 indexed citations

16.

Seya, Tsukasa, Tomoko Hara, Misako Matsumoto, et al.. (1993). Membrane cofactor protein (MCP, CD46) in seminal plasma and on spermatozoa in normal and “sterile” subjects. European Journal of Immunology. 23(6). 1322–1327. 40 indexed citations

17.

Seya, Tsukasa, et al.. (1992). Two modes of homologous C3 deposition on Ramos Burkitt's lymphoma cell substrains co-expressing DAF (CD55), CD59, and CR2 (CD21), and on cells lacking them. International Immunology. 4(12). 1361–1371. 9 indexed citations

18.

Seya, Tsukasa, Tomoko Hara, Misako Matsumoto, Yuji Sugita, & Hitoshi Akedo. (1990). Complement-mediated tumor cell damage induced by antibodies against membrane cofactor protein (MCP, CD46).. The Journal of Experimental Medicine. 172(6). 1673–1680. 97 indexed citations

19.

Komatsu, Keiko, Hiroyuki Nakamura, Kiyoko Shinkai, & Hitoshi Akedo. (1989). Secretion of Transforming Growth Factor‐ß by Human Myelogenous Leukemic Cells and Its Possible Role in Proliferation of the Leukemic Cells. Japanese Journal of Cancer Research. 80(10). 928–931. 4 indexed citations

20.

Mukai, Mutsuko, Kiyoko Shinkai, Keiko Komatsu, & Hitoshi Akedo. (1989). Potentiation of Invasive Capacity of Rat Ascites Hepatoma Cells by Transforming Growth Factor‐β. Japanese Journal of Cancer Research. 80(2). 107–110. 35 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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