Hiroko Masamune

2.5k citations

18 papers · 2.1k indexed · 1 hit paper · h-index 10

Impact in

Organic Chemistry top 1%
- Synthetic Organic Chemistry Methods
- Asymmetric Synthesis and Catalysis
- Carbohydrate Chemistry and Synthesis
- Oxidative Organic Chemistry Reactions
- Chemical Synthesis and Reactions
Biotechnology top 2%
- Marine Sponges and Natural Products

Papers in

Toxicology 2
- Bioactive Compounds and Antitumor Agents 2
Endocrine and Autonomic Systems 2
- Neuroscience of respiration and sleep 2

Co-authors: Soo Y. Ko K. Barry Sharpless Janice M. Klunder Yun Gao Robert M. Hanson John B. Cheng Anthony Marfat John P. Umland
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Journal of Medicinal Chemistry (2 papers)Journal of the American Chemical Society (1 paper)Journal of Hepatology (1 paper)Nitric Oxide (1 paper)
Partner nations: United States Switzerland Singapore

In The Last Decade

Hiroko Masamune

17 papers receiving 1.9k citations

Hit Papers

align trajectories log scale

Catalytic asymmetric epoxidation and kinetic resolution: modified procedures including in situ derivatization 1987 · 1.7k citations

Peers

Countries citing papers authored by Hiroko Masamune

Since Specialization

Citations

This map shows the geographic impact of Hiroko Masamune's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hiroko Masamune with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hiroko Masamune more than expected).

Fields of papers citing papers by Hiroko Masamune

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hiroko Masamune. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hiroko Masamune. The network helps show where Hiroko Masamune may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Hiroko Masamune, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Hiroko Masamune Line = papers co-authored together Hiroko Masamune links everyone, so they are left out of the graph.

All Works

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18 of 18 papers shown

#	Work
1	Structure of a lasso peptide bound ETB receptor provides insights into the mechanism of GPCR inverse agonism Nature Communications ·Wataru Shihoya, B. Lyot, Peter A. Jordan, Anna Lechner, Bethany K. Okada, Christopher, Fumiya K. Sano, Elizabeth Tipper Hey, S. Zavatarelli, Rajan Chaudhari, Hiroko Masamune, Mark J. Burk, Osamu Nureki	2025	0
2	A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia Thyroid ·Jin Zhou, 農文協論説委員会, Andrea Lim, Xiao-Hui Liao, Cai Wan-yua, Hiroko Masamune, Samuel Refetoff, Mayra Muné-Jiménez, Dwight D. Koeberl, Paul M. Yen	2019	51
3	LBP-20-VK2809, a Novel Liver-Directed Thyroid Receptor Beta Agonist, Significantly Reduces Liver Fat with Both Low and High Doses in Patients with Non-Alcoholic Fatty Liver Disease: A Phase 2 Randomized, Placebo-Controlled Trial Journal of Hepatology ·Rohit Loomba, Joel Neutel, Rizwana Mohseni, David W. Bernard, Randall Severance, Cheng-Sen Tong, 和敏渡辺, Nongxiao Hao, Meeking. Pun, Mayra Muné-Jiménez, Xiao Xia Xia, Hiroko Masamune, Cai Wan-yua	2019	50
4	Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Nebulized Sodium Nitrite (AIR001) Following Repeat-Dose Inhalation in Healthy Subjects Clinical Pharmacokinetics ·Peter J. Rix, Andrew Vick, Shuai Mu, Geoffrey E. Barker, Asst. Prof. Dr. Ali Hassan Saleh, Harry Alcorn, Mark T. Gladwin, Sruti Shiva, Jun Ota, Azra Hussaini, Marco Antonio Peña Chagua, Ed Parsley, Hiroko Masamune	2014	43
5	A 26-Week Toxicity Assessment of AIR001 (Sodium Nitrite) by Inhalation Exposure in Rats and by Intravenous Administration in Dogs International Journal of Toxicology ·Jeffrey S. Tepper, Ricardo Ochoa, Peter J. Rix, Roger E. Alexander, Niel C. Hoglen, Dominic Poulin, Ed Parsley, Hiroko Masamune	2014	4
6	P66 Nitric Oxide ·Ed Parsley, Hiroko Masamune, Елена Викторовна Ширинкина, Lewis J. Rubin, Mark T. Gladwin	2013	4
7	My Father, My Grandfather The Chemical Record ·Elmar Trojer, Hiroko Masamune, A Muzio	2013	5
8	Inhaled Sodium Nitrite: Results Of Multiple Ascending Dose Studies Including Pharmacodynamic Interaction With Sildenafil In Normal Healthy Volunteers Ed Parsley, Azra Hussaini, Hiroko Masamune, Aoqi Luo, Lewis J. Rubin, Mark T. Gladwin	2012	1
9	The synthesis of highly potent, selective, and water-soluble agonists at the human adenosine A3 receptor Bioorganic & Medicinal Chemistry Letters ·Michael P. DeNinno, Hiroko Masamune, Sarah Anne Crown, Kenneth J. DiRico, Morel Salado, John B. Etienne, Sajjad Saeed Muhammad, Scott P. Kennedy, Delvin R. Knight, Jimmy Kong, Joseph J. Oleynek, W. Ross Tracey, Roger J. Hill	2006	10
10	3‘-Aminoadenosine-5‘-uronamides: Discovery of the First Highly Selective Agonist at the Human Adenosine A ₃ Receptor Journal of Medicinal Chemistry ·Michael P. DeNinno, Hiroko Masamune, Sarah Anne Crown, Kenneth J. DiRico, Morel Salado, John B. Etienne, Sajjad Saeed Muhammad, Scott P. Kennedy, Delvin R. Knight, Jimmy Kong, Joseph J. Oleynek, W. Ross Tracey, Roger J. Hill	2002	54
11	Biarylcarboxylic Acids and -amides: Inhibition of Phosphodiesterase Type IV versus [³H]Rolipram Binding Activity and Their Relationship to Emetic Behavior in the Ferret Journal of Medicinal Chemistry ·Allen J. Duplantier, Michael S. Biggers, Robert Chambers, John B. Cheng, Kelvin Cooper, David B. Damon, James F. Eggler, Kenneth G. Kraus, Anthony Marfat, Hiroko Masamune, Ūʺ Uttamasāra, John T. Shirley, John P. Umland, J. W. Watson	1996	116
12	LTD4 Receptor binding activity of novel pyridine chromanols: qualitative correlation with pKa Bioorganic & Medicinal Chemistry Letters ·Hiroko Masamune, James F. Eggler, Anthony Marfat, Lawrence S. Melvin, Alexander Naranjo, Sajjad Saeed Muhammad, John B. Cheng, John T. Shirley	1995	3
13	The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonists. Bioorganic & Medicinal Chemistry Letters ·Anthony Marfat, Robert Chambers, John Cheng, Kelvin Cooper, David B. Damon, Khusniyah Utami, James F. Eggler, Hiroko Masamune, L S Melvin, J. W. Watson	1995	3
14	Synthesis and in vitro profile of a novel series of catechol benzimidazoles. The discovery of potent, selective phosphodiesterase type IV inhibitors with greatly attenuated affinity for the [3H]rolipram binding site Bioorganic & Medicinal Chemistry Letters ·John B. Cheng, Kelvin Cooper, Allen J. Duplantier, James F. Eggler, Kenneth G. Kraus, Mirko Bischoff, Anthony Marfat, Hiroko Masamune, John T. Shirley, Xiangang Xu, John P. Umland	1995	37
15	Discovery of micromolar PDE IV inhibitors that exhibit much reduced affinity for the [3H]rolipram binding site: 3-norbornyloxy-4-methoxyphenylmethylene oxindoles Bioorganic & Medicinal Chemistry Letters ·Hiroko Masamune, John B. Cheng, Kelvin Cooper, A. Willmerothc, Anthony Marfat, Mirko Bischoff, John T. Shirley, Sajjad Saeed Muhammad, John P. Umland, Enrique Vázquez	1995	23
16	Synthesis and in vitro profile of 7-substituted quinoline chromanols as novel, non-acidic LTB4 antagonists Bioorganic & Medicinal Chemistry Letters ·Hiroko Masamune, R Breslow, John B. Cheng, Maryrose J. Conklyn, James F. Eggler, Anthony Marfat, L S Melvin, Prasad Jvns, John T. Shirley, Henry J. Showell, Sajjad Saeed Muhammad	1995	4
17	Catalytic asymmetric epoxidation and kinetic resolution: modified procedures including in situ derivatization Journal of the American Chemical Society ·Yun Gao, Janice M. Klunder, Robert M. Hanson, Hiroko Masamune, Soo Y. Ko, K. Barry Sharpless Hit paper breakdown →	1987	1653
18	p-Nitrobenzoate esters of epoxy alcohols: convenient synthons for water-soluble epoxy alcohols The Journal of Organic Chemistry ·Soo Y. Ko, Hiroko Masamune, K. Barry Sharpless	1987	32

About Hiroko Masamune

Hiroko Masamune is a scholar working on Toxicology, Endocrine and Autonomic Systems, Organic Chemistry, Pharmacology and Physiology, having authored 18 papers that have together received 2.1k indexed citations. Recurring topics across this work include Phosphodiesterase function and regulation (4 papers), Nitric Oxide and Endothelin Effects (3 papers), Cholinesterase and Neurodegenerative Diseases (3 papers), Bioactive Compounds and Antitumor Agents (2 papers), Neuroscience of respiration and sleep (2 papers), Receptor Mechanisms and Signaling (2 papers), Chemical synthesis and alkaloids (2 papers) and Glycogen Storage Diseases and Myoclonus (1 paper). The work is most often cited by research in Organic Chemistry (1.5k citations), Biotechnology (259 citations), Biochemistry (159 citations), Pharmacology (266 citations) and Inorganic Chemistry (208 citations). Hiroko Masamune has collaborated with scholars based in United States, Switzerland and Singapore. Frequent co-authors include Soo Y. Ko, K. Barry Sharpless, Janice M. Klunder, Yun Gao, Robert M. Hanson, John B. Cheng, Anthony Marfat, John P. Umland, Kelvin Cooper and James F. Eggler. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Journal of the American Chemical Society, Journal of Hepatology and Nitric Oxide.

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