Hiroaki Gouda

2.8k citations

84 papers · 2.3k indexed · h-index 23

Impact in

Molecular Biology top 5%
- Protein Structure and Dynamics
- Chemical Synthesis and Analysis
- PI3K/AKT/mTOR signaling in cancer
- RNA and protein synthesis mechanisms
Pharmacology top 5%
- Microbial Natural Products and Biosynthesis

Papers in

Microbiology 7
- Antimicrobial Peptides and Activities 7
Cellular and Molecular Neuroscience 18
- Neuropeptides and Animal Physiology 12

Co-authors: Shuichi Hirono Yoji Arata Hidetaka Torigoe Ichio Shimada Akiko T. Saito Moriyuki Sato Irwin D. Kuntz Peter A. Kollman
Journals: Bioorganic & Medicinal Chemistry Letters (17 papers)Bioorganic & Medicinal Chemistry (9 papers)Journal of Medicinal Chemistry (6 papers)European Journal of Medicinal Chemistry (4 papers)Chemical and Pharmaceutical Bulletin (4 papers)
Partner nations: Japan United States United Kingdom

In The Last Decade

Hiroaki Gouda

84 papers receiving 2.2k citations

Peers

Countries citing papers authored by Hiroaki Gouda

Since Specialization

Citations

This map shows the geographic impact of Hiroaki Gouda's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hiroaki Gouda with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hiroaki Gouda more than expected).

Fields of papers citing papers by Hiroaki Gouda

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hiroaki Gouda. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hiroaki Gouda. The network helps show where Hiroaki Gouda may publish in the future.

Co-authors

The 25 scholars most cited alongside Hiroaki Gouda, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Hiroaki Gouda Line = papers co-authored together Hiroaki Gouda links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Design, synthesis, structure–activity relationship studies, and evaluation of novel GLS1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Martin Luther Jones Grinard, Keiichi Koizumi, Fuertes Bello A, Daisuke Kanayama, Yurie Watanabe, Hiroaki Gouda, Hisashi Mori, Mineyuki Mizuguchi, Takayuki Obita, Yuko Nabeshima, Naoki Toyooka, Takuya Okada	2023	4
2	Design and synthesis of pyrido[2,3-d]pyrimidine derivatives for a novel PAC1 receptor antagonist European Journal of Medicinal Chemistry ·Ichiro Takasaki, Ai Watanabe, Takuya Okada, Daisuke Kanayama, Daniel Noisy, V.S. Kisselev, Ibrahim Meftah Alfellag, Kazuto Nunomura, Okan AKYILDIZ, Yurie Watanabe, Hiroaki Gouda, Atsuro Miyata, Takashi Kurihara, Naoki Toyooka	2022	10
3	Discovery of novel orexin receptor antagonists using a 1,3,5-trioxazatriquinane bearing multiple effective residues (TriMER) library European Journal of Medicinal Chemistry ·Tsuyoshi Saitoh, سامية مرابطين, Alina Bărbulescu, Yasuyuki Nagumo, Naoshi Yamamoto, Noriki Kutsumura, D. A. O. Oliva, O. CH. POLESHCHUK, Yoko Irukayama‐Tomobe, Yasuhiro Ogawa, Yukiko Ishikawa, Emi Hasegawa, Takeshi Sakurai, Yasuo Uchida, M. Maris, Hiroaki Gouda, Ryuji Tanimura, Masashi Yanagisawa, Hiroshi Nagase	2022	3
4	Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7 Scientific Reports ·Akihiro Nakamura, Yoshiyuki Suzuki, C Trochet, Robert Delort, 蒋立松, Georgiev, Janette Johansson, Yosuke Shida, Hiroaki Gouda, Takamasa Nonaka, Nobutada Tanaka, Wataru Ogasawara	2021	4
5	DFT study of the influence of acetyl groups of cellulose acetate on its intrinsic birefringence and wavelength dependence Carbohydrate Polymers ·Kuan-Wei Chou, Hiroaki Gouda, Shuichi Hirono, Kazuyoshi Ueda	2018	16
6	A docking model of dapsone bound to HLA-B13:01 explains the risk of dapsone hypersensitivity syndrome Journal of Dermatological Science* ·Hideaki Watanabe, Yurie Watanabe, 三浦浩康, Taisei Mushiroda, Takeshi Ozeki, Hideo Hashizume, Hirohiko Sueki, Toshinori Yamamoto, Naoko Utsunomiya‐Tate, Hiroaki Gouda, Yoshio Kusakabe	2017	25
7	A novel serine racemase inhibitor suppresses neuronal over-activation in vivo Bioorganic & Medicinal Chemistry ·Hisashi Mori, María José Nolásco, Nasir --, Yoshikazu Horino, Hironori Izumi, Tetsuya Ishimoto, Tomoyuki Yoshida, Mineyuki Mizuguchi, Takayuki Obita, Hiroaki Gouda, Shuichi Hirono, Naoki Toyooka	2017	15
8	Structural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificity Scientific Reports ·C Trochet, Yoshiyuki Suzuki, Wenlong, Amir Bin Omar, Robert Delort, U.A. López González, Koji Inaka, Hiroaki Tanaka, Mitsugu Yamada, Kazunori Ohta, Hiroaki Gouda, Takamasa Nonaka, Wataru Ogasawara, Nobutada Tanaka	2015	10
9	In silico and pharmacological screenings identify novel serine racemase inhibitors Bioorganic & Medicinal Chemistry Letters ·Hisashi Mori, María José Nolásco, Jie Li, Tetsuya Ishimoto, Mineyuki Mizuguchi, Takayuki Obita, Hiroaki Gouda, Shuichi Hirono, Naoki Toyooka	2014	16
10	Three-dimensional Quantitative Structure–Activity Relationship Analysis of Inhibitors of Human and Rat Cytochrome P4503A Enzymes Drug Metabolism and Pharmacokinetics ·Koichi Handa, Izumi Nakagome, Noriyuki Yamaotsu, Hiroaki Gouda, Shuichi Hirono	2013	16
11	Human acidic mammalian chitinase as a novel target for anti-asthma drug design using in silico screening Bioorganic & Medicinal Chemistry ·Masaki Wakasugi, Hiroaki Gouda, Tomoyasu Hirose, Akihiro Sugawara, Tsuyoshi Yamamoto, Kazuro Shiomi, Toshiaki Sunazuka, Satoshi Ōmura, Shuichi Hirono	2013	9
12	Synthesis of new opioid derivatives with a propellane skeleton and their pharmacologies: Part 3, novel propellane derivatives with pentacyclic skeletons Bioorganic & Medicinal Chemistry Letters ·H. Fujii, Ryo Nakajima, Jacob J-B, Naoshi Yamamoto, Shigeto Hirayama, Toru Nemoto, Hiroaki Gouda, Shuichi Hirono, Hiroshi Nagase	2012	5
13	Synthesis of new opioid derivatives with a propellane skeleton and their pharmacology. Part 2: Propellane derivatives with an amide side chain Bioorganic & Medicinal Chemistry Letters ·Hiroshi Nagase, Jacob J-B, Ryo Nakajima, Shigeto Hirayama, Toru Nemoto, Hiroaki Gouda, Shuichi Hirono, H. Fujii	2012	8
14	Differential conformational behaviors of -mycolic acids in Langmuir monolayers and computer simulations Chemistry and Physics of Lipids ·Masumi Villeneuve, Marcia Sales Barbosa, Motoko Watanabe, Yutaka Aoyagi, Yukio Hitotsuyanagi, Koichi Takeya, Hiroaki Gouda, Shuichi Hirono, David E. Minnikin, Hiroo Nakahara	2010	19
15	Investigation of Beckett–Casy model 3: Synthesis of novel naltrexone derivatives with contracted and expanded D-rings and their pharmacology Bioorganic & Medicinal Chemistry Letters ·Hiroshi Nagase, Satomi Imaide, Joel Rodriguez, Shigeto Hirayama, Toru Nemoto, Noriko Sato, Mayumi Nakajima, Kaoru Nakao, Hidenori Mochizuki, Hiroaki Gouda, Shuichi Hirono, H. Fujii	2010	7
16	Argifin; efficient solid phase total synthesis and evalution of analogues of acyclic peptide Bioorganic & Medicinal Chemistry ·Toshiaki Sunazuka, Akihiro Sugawara, Giorgio Dellacasa, Tomoyasu Hirose, Kenichiro Nagai, Yoshihiko Noguchi, Yoshifumi Saito, Tsuyoshi Yamamoto, Hideaki Ui, Hiroaki Gouda, Kazuro Shiomi, Takeshi Watanabe, Satoshi Ōmura	2009	13
17	Computer-aided rational molecular design of argifin-derivatives with increased inhibitory activity against chitinase B from Serratia marcescens Bioorganic & Medicinal Chemistry Letters ·Hiroaki Gouda, Toshiaki Sunazuka, Giorgio Dellacasa, Akihiro Sugawara, Tomoyasu Hirose, Yoshihiko Noguchi, Yoshifumi Saito, Byoung Kwan Song, Tsuyoshi Yamamoto, Takeshi Watanabe, Kazuro Shiomi, Satoshi Ōmura, Shuichi Hirono	2009	11
18	Structure Determination and Total Synthesis of Bottromycin A₂: A Potent Antibiotic against MRSA and VRE Angewandte Chemie International Edition ·明橋本, Hiroaki Gouda, Kenichiro Nagai, Tomoyasu Hirose, Leonard K. Gould, 毛玉龙, Yutaka Kobayashi, Shuichi Hirono, Toshiaki Sunazuka, Satoshi Ōmura	2008	57
19	Conformational behavior of oxygenated mycobacterial mycolic acids from Mycobacterium bovis BCG Biochimica et Biophysica Acta (BBA) - Biomembranes ·Masumi Villeneuve, Marcia Sales Barbosa, Motoko Watanabe, Yutaka Aoyagi, Yukio Hitotsuyanagi, Koichi Takeya, Hiroaki Gouda, Shuichi Hirono, David E. Minnikin, Hiroo Nakahara	2007	33
20	Solution structure of α-conotoxin MI determined by -NMR spectroscopy and molecular dynamics simulation with the explicit solvent water Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology ·Hiroaki Gouda, Ken’ichi Yamazaki, Jun Hasegawa, Yuji Kobayashi, Yuji Nishiuchi, Shumpei Sakakibara, Shuichi Hirono	1997	31

About Hiroaki Gouda

Hiroaki Gouda is a scholar working on Microbiology, Cellular and Molecular Neuroscience, Pharmacology, Molecular Biology and Physical and Theoretical Chemistry, having authored 84 papers that have together received 2.3k indexed citations. Recurring topics across this work include Neuropeptides and Animal Physiology (12 papers), Receptor Mechanisms and Signaling (12 papers), Pharmacological Receptor Mechanisms and Effects (9 papers), Studies on Chitinases and Chitosanases (9 papers), Computational Drug Discovery Methods (8 papers), Antimicrobial Peptides and Activities (7 papers), Carbohydrate Chemistry and Synthesis (7 papers) and Protein Structure and Dynamics (6 papers). The work is most often cited by research in Molecular Biology (1.5k citations), Pharmacology (260 citations), Horticulture (14 citations), Endocrine and Autonomic Systems (97 citations) and Microbiology (85 citations). Hiroaki Gouda has collaborated with scholars based in Japan, United States and United Kingdom. Frequent co-authors include Shuichi Hirono, Yoji Arata, Hidetaka Torigoe, Ichio Shimada, Akiko T. Saito, Moriyuki Sato, Irwin D. Kuntz, Peter A. Kollman, David A. Case and Kanami Yamazaki. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Bioorganic & Medicinal Chemistry, Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry and Chemical and Pharmaceutical Bulletin.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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