Hend Kothayer

663 citations

26 papers · 524 · h-index 15

Impact in

Organic Chemistry top 10%
- Synthesis and biological activity
- Quinazolinone synthesis and applications
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Biological Evaluation
- Click Chemistry and Applications
Toxicology

Papers in

Organic Chemistry 17
- Quinazolinone synthesis and applications 9
- Synthesis and biological activity 8
- Synthesis and Characterization of Heterocyclic Compounds 5
- Synthesis and Biological Evaluation 4
- Click Chemistry and Applications 2
Molecular Biology 15
- Phenothiazines and Benzothiazines Synthesis and Activities 4

Co-authors: Samy M. Ibrahim (9 shared papers)Samar Rezq (7 shared papers)Mohamed M. Baraka (6 shared papers)Andrew D. Westwell (6 shared papers)Damián G. Romero (5 shared papers)Osama I. El‐Sabbagh (5 shared papers)Malathy P.V. Shekhar (4 shared papers)Kaushlendra Tripathi (2 shared papers)
Journals: Archiv der Pharmazie (5 papers)European Journal of Medicinal Chemistry (4 papers)Journal of Enzyme Inhibition and Medicinal Chemistry (2 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)Bioorganic Chemistry (2 papers)
Partner nations: Egypt United States United Kingdom

In The Last Decade

Hend Kothayer

25 papers receiving 516 citations

Peers

Countries citing papers authored by Hend Kothayer

Since Specialization

Citations

This map shows the geographic impact of Hend Kothayer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hend Kothayer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hend Kothayer more than expected).

Fields of papers citing papers by Hend Kothayer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hend Kothayer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hend Kothayer. The network helps show where Hend Kothayer may publish in the future.

Co-authors

The 25 scholars most cited alongside Hend Kothayer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Hend Kothayer Line = papers co-authored together Hend Kothayer links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 26 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance Oncogene ·Ranganatha R. Somasagara, Sebastian M. Spencer, Kaushlendra Tripathi, David W. Clark, Chinnadurai Mani, Luciana Madeira da Silva, Jennifer Scalici, Hend Kothayer, Andrew D. Westwell, Rodney P. Rocconi, Komaraiah Palle	2017	56
2	Novel Inhibitors of Rad6 Ubiquitin Conjugating Enzyme: Design, Synthesis, Identification, and Functional Characterization Molecular Cancer Therapeutics ·Matthew A. Sanders, Ghali Brahemi, Pratima Nangia‐Makker, Vitaly Balan, Matteo Morelli, Hend Kothayer, Andrew D. Westwell, Malathy P.V. Shekhar	2013	53
3	Synthesis and in vitro anticancer evaluation of some 4,6-diamino-1,3,5-triazine-2-carbohydrazides as Rad6 ubiquitin conjugating enzyme inhibitors Bioorganic & Medicinal Chemistry Letters ·Hend Kothayer, Sebastian M. Spencer, Kaushlendra Tripathi, Andrew D. Westwell, Komaraiah Palle	2016	47
4	Design and synthesis of novel quinazolinones conjugated ibuprofen, indole acetamide, or thioacetohydrazide as selective COX-2 inhibitors: anti-inflammatory, analgesic and anticancer activities Journal of Enzyme Inhibition and Medicinal Chemistry ·Asmaa Sakr, Samar Rezq, Samy M. Ibrahim, Eman Soliman, Mohamed M. Baraka, Damián G. Romero, Hend Kothayer	2021	46
5	Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition European Journal of Medicinal Chemistry ·Amany M. Ghanim, Samar Rezq, Tarek S. Ibrahim, Damián G. Romero, Hend Kothayer	2021	41
6	Gold nanoparticle conjugated Rad6 inhibitor induces cell death in triple negative breast cancer cells by inducing mitochondrial dysfunction and PARP-1 hyperactivation: Synthesis and characterization Nanomedicine Nanotechnology Biology and Medicine ·Brittany Haynes, Yanhua Zhang, Fangchao Liu, Jing Li, Sarah A. Petit, Hend Kothayer, Xun Bao, Andrew D. Westwell, Guangzhao Mao, Malathy P.V. Shekhar	2015	39
7	Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides Bioorganic & Medicinal Chemistry Letters ·Hend Kothayer, Abdalla A. El‐Shanawani, Mansour E. Abu Kull, Osama I. El‐Sabbagh, Malathy P.V. Shekhar, Andrea Brancale, Arwyn T. Jones, Andrew D. Westwell	2013	29
8	Synthesis of New 2,3‐Dihydroquinazolin‐4(1H)‐one Derivatives for Analgesic and Anti‐inflammatory Evaluation Archiv der Pharmazie ·Osama I. El‐Sabbagh, Samy M. Ibrahim, Mohamed M. Baraka, Hend Kothayer	2010	26
9	Synthesis, Anticonvulsant Activity, and SAR Study of Novel 4‐Quinazolinone Derivatives Archiv der Pharmazie ·Nada A. Noureldin, Hend Kothayer, El‐Sayed M. Lashine, Mohamed M. Baraka, Wafaa I. El‐Eraky, Sally A. El Awdan	2017	26
10	1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inflammatory and analgesic agents with an improved gastric profile: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study Bioorganic Chemistry ·Asmaa Sakr, Hend Kothayer, Samy M. Ibrahim, Mohamed M. Baraka, Samar Rezq	2018	25
11	Synthesis of new benzotriazepin-5(2H)-one derivatives of expected antipsychotic activity Medicinal Chemistry Research ·Samy M. Ibrahim, Mohamed M. Baraka, Osama I. El‐Sabbagh, Hend Kothayer	2012	22
12	Synthesis, in vivo and in silico evaluation of novel 2,3‐dihydroquinazolin‐4(1H)‐one derivatives as potential anticonvulsant agents Drug Development Research ·Hend Kothayer, Samy M. Ibrahim, Moustafa K. Soltan, Samar Rezq, Shireen S. Mahmoud	2018	17
13	Design, synthesis and biological evaluation of novel quinazoline-2,4-diones conjugated with different amino acids as potential chitin synthase inhibitors European Journal of Medicinal Chemistry ·Nada A. Noureldin, Hend Kothayer, El‐Sayed M. Lashine, Mohamed M. Baraka, Yanrong Huang, Bing Li, Qinggang Ji	2018	17
14	Magic shotgun approach to anti-inflammatory pharmacotherapy: Synthesis of novel thienopyrimidine monomers/heterodimer as dual COX-2 and 15-LOX inhibitors endowed with potent antioxidant activity European Journal of Medicinal Chemistry ·Sara Elsayed, Ahmed S. Abdelkhalek, Samar Rezq, Mansour E. Abu Kull, Damián G. Romero, Hend Kothayer	2023	16
15	Triple targeting of mutant EGFR ^L858R/T790M , COX-2, and 15-LOX: design and synthesis of novel quinazolinone tethered phenyl urea derivatives for anti-inflammatory and anticancer evaluation Journal of Enzyme Inhibition and Medicinal Chemistry ·Hend Kothayer, Samar Rezq, Ahmed S. Abdelkhalek, Damián G. Romero, Samar S. Elbaramawi	2023	14
16	Synthesis of new multitarget-directed ligands containing thienopyrimidine nucleus for inhibition of 15-lipoxygenase, cyclooxygenases, and pro-inflammatory cytokines European Journal of Medicinal Chemistry ·Ahmed S. Abdelkhalek, Hend Kothayer, Samar Rezq, Khaled Y. Orabi, Damián G. Romero, Osama I. El‐Sabbagh	2023	11
17	Quinazoline‐tethered hydrazone: A versatile scaffold toward dual anti‐TB and EGFR inhibition activities in NSCLC Archiv der Pharmazie ·Aya M. Emam, Achyut Dahal, Sitanshu S. Singh, Rodrigo D. Tosso, Samy M. Ibrahim, Mohamed El‐Sadek, Seetharama D. Jois, Ricardo D. Enriz, Hend Kothayer	2021	10
18	Optimised synthesis of diamino-triazinylmethyl benzoates as inhibitors of Rad6B ubiquitin conjugating enzyme Tetrahedron Letters ·Hend Kothayer, Matteo Morelli, Ghali Brahemi, Abdalla A. El‐Shanawani, Mansour E. Abu Kull, Osama I. El‐Sabbagh, Malathy P.V. Shekhar, Andrew D. Westwell	2014	7
19	Vitamin D3 mitigates myopathy and metabolic dysfunction in rats with metabolic syndrome: the potential role of dipeptidyl peptidase-4 Naunyn-Schmiedeberg s Archives of Pharmacology ·Nourhan O Shoier, Salah A. Ghareib, Hend Kothayer, Amira Ebrahim Alsemeh, Shaimaa S. El-Sayed	2024	5
20	Novel 2‐[thio]acetamide linked quinazoline/1,2,4‐triazole/chalcone hybrids: Design, synthesis, and anticancer activity as EGFR inhibitors and apoptotic inducers Archiv der Pharmazie ·Ahmed S. Abdelkhalek, Hend Kothayer, Moustafa K. Soltan, Samy M. Ibrahim, Samar S. Elbaramawi	2024	5

About Hend Kothayer

Hend Kothayer is a scholar working on Organic Chemistry, Molecular Biology, Pharmacology, Infectious Diseases and Oncology, having authored 26 papers that have together received 524 indexed citations. Recurring topics across this work include Quinazolinone synthesis and applications (9 papers), Synthesis and biological activity (8 papers), Inflammatory mediators and NSAID effects (5 papers), Synthesis and Characterization of Heterocyclic Compounds (5 papers), Phenothiazines and Benzothiazines Synthesis and Activities (4 papers), Synthesis and Biological Evaluation (4 papers), Click Chemistry and Applications (2 papers) and Antimicrobial Peptides and Activities (2 papers). The work is most often cited by research in Organic Chemistry (304 citations), Toxicology (14 citations), Pharmacology (63 citations), Molecular Biology (212 citations) and Oncology (62 citations). Hend Kothayer has collaborated with scholars based in Egypt, United States and United Kingdom. Frequent co-authors include Samy M. Ibrahim, Samar Rezq, Mohamed M. Baraka, Andrew D. Westwell, Damián G. Romero, Osama I. El‐Sabbagh, Malathy P.V. Shekhar, Kaushlendra Tripathi, Komaraiah Palle and Tarek S. Ibrahim. Their work appears in journals such as Archiv der Pharmazie, European Journal of Medicinal Chemistry, Journal of Enzyme Inhibition and Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters and Bioorganic Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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