Helmut Romig

2.1k citations

23 papers · 1.8k · h-index 17

Impact in

Physiology top 2%
- Alzheimer's disease research and treatments
Cell Biology top 5%
- Cellular transport and secretion

Papers in

Molecular Biology 17
- Genomics and Chromatin Dynamics 3
- Cancer therapeutics and mechanisms 2
- Protein Structure and Dynamics 2
- S100 Proteins and Annexins 2
Physiology 13
- Alzheimer's disease research and treatments 13

Co-authors: Christian Haass (12 shared papers)Harald Steiner (9 shared papers)Ralf Baumeister (7 shared papers)Brigitte Pesold (6 shared papers)Anja Capell (7 shared papers)Martin Citron (4 shared papers)Frank O. Fackelmayer (2 shared papers)Melissa G. Grim (4 shared papers)
Journals: Journal of Biological Chemistry (5 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)Nature Cell Biology (2 papers)Biochemistry (2 papers)SLAS DISCOVERY (1 paper)
Partner nations: Germany United States United Kingdom

In The Last Decade

Helmut Romig

23 papers receiving 1.7k citations

Peers

Countries citing papers authored by Helmut Romig

Since Specialization

Citations

This map shows the geographic impact of Helmut Romig's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Helmut Romig with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Helmut Romig more than expected).

Fields of papers citing papers by Helmut Romig

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Helmut Romig. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Helmut Romig. The network helps show where Helmut Romig may publish in the future.

Co-authors

The 25 scholars most cited alongside Helmut Romig, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Helmut Romig Line = papers co-authored together Helmut Romig links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 23 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A Loss of Function Mutation of Presenilin-2 Interferes with Amyloid β-Peptide Production and Notch Signaling Journal of Biological Chemistry ·Harald Steiner, Karen Duff, Anja Capell, Helmut Romig, Melissa G. Grim, Sarah Lincoln, John Hardy, Xin Yu, Melanie Picciano, Katja Fechteler, Martin Citron, Raphael Kopan, Brigitte Pesold, Simone Keck, Miriam Baader, Taisuke Tomita, Takeshi Iwatsubo, Ralf Baumeister, Christian Haass	1999	258
2	Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases Nature Cell Biology ·Harald Steiner, Marcus Kostka, Helmut Romig, Gabriele Basset, Brigitte Pesold, John Hardy, Anja Capell, Liane Meyn, Melissa L. Grim, Ralf Baumeister, Katja Fechteler, Christian Haass	2000	228
3	Characterization of SAF-A, a novel nuclear DNA binding protein from HeLa cells with high affinity for nuclear matrix/scaffold attachment DNA elements. The EMBO Journal ·Helmut Romig, Frank O. Fackelmayer, Andrea Renz, U. Ramsperger, A. Richter	1992	213
4	Expression of Alzheimer’s Disease-associated Presenilin-1 Is Controlled by Proteolytic Degradation and Complex Formation Journal of Biological Chemistry ·Harald Steiner, Anja Capell, Brigitte Pesold, Martin Citron, Peter M. Kloetzel, Dennis J. Selkoe, Helmut Romig, Klaus Mendla, Christian Haass	1998	165
5	Presenilin-1 differentially facilitates endoproteolysis of the β-amyloid precursor protein and Notch Nature Cell Biology ·Anja Capell, Harald Steiner, Helmut Romig, Simone Keck, Miriam Baader, Melissa G. Grim, Ralf Baumeister, Christian Haass	2000	128
6	The Biological and Pathological Function of the Presenilin-1 ΔExon 9 Mutation Is Independent of Its Defect to Undergo Proteolytic Processing Journal of Biological Chemistry ·Harald Steiner, Helmut Romig, Melissa G. Grim, Uwe Philipp, Brigitte Pesold, Martin Citron, Ralf Baumeister, Christian Haass	1999	111
7	Zebrafish (Danio rerio) Presenilin Promotes Aberrant Amyloid β-Peptide Production and Requires a Critical Aspartate Residue for Its Function in Amyloidogenesis Biochemistry ·Uwe Leimer, Klaus Lun, Helmut Romig, Jochen Walter, Jürgen Grünberg, Michael Brand, Christian Haass	1999	98
8	Elevated vulnerability to oxidative stress‐induced cell death and activation of caspase‐3 by the Swedish amyloid precursor protein mutation Journal of Neuroscience Research ·Anne Eckert, Barbara Steiner, Celio A. Marques, Steffen Leutz, Helmut Romig, Christian Haass, Wernér E.G. Müller	2001	87
9	Amyloidogenic Function of the Alzheimer's Disease-Associated Presenilin 1 in the Absence of Endoproteolysis Biochemistry ·Harald Steiner, Helmut Romig, Brigitte Pesold, Uwe Philipp, Miriam Baader, Martin Citron, Hansruedi Loetscher, Helmut Jacobsen, Christian Haass	1999	76
10	Separation of presenilin function in amyloid β-peptide generation and endoproteolysis of Notch Proceedings of the National Academy of Sciences ·Luka Kulic, Jochen Walter, Gerd Multhaup, David B. Teplow, Ralf Baumeister, Helmut Romig, Anja Capell, Harald Steiner, Christian Haass	2000	74
11	A Pathogenic Presenilin-1 Deletion Causes Abberrant Aβ42 Production in the Absence of Congophilic Amyloid Plaques Journal of Biological Chemistry ·Harald Steiner, Tamás Révész, Manuela Neumann, Helmut Romig, Melissa G. Grim, Brigitte Pesold, Hans A. Kretzschmar, John Hardy, Janice L. Holton, Ralf Baumeister, Henry Houlden, Christian Haass	2001	71
12	Characterisation of two intronic nuclear‐matrix‐attachment regions in the human DNA topoisomerase I gene European Journal of Biochemistry ·Helmut Romig, Jürgen Ruff, Frank O. Fackelmayer, M. S. Patil, Arndt Richter	1994	35
13	Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo ACS Medicinal Chemistry Letters ·Christian A. Kuttruff, Marco Ferrara, Tom Bretschneider, S. Hoerer, Sandra Handschuh, Bernd Nosse, Helmut Romig, Paul Nicklin, Gerald J. Roth	2017	35
14	Expression of the topoisomerase I gene in serum stimulated human fibroblasts Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ·Helmut Romig, Arndt Richter	1990	34
15	A Loss of Function Mutant of the Presenilin Homologue SEL-12 Undergoes Aberrant Endoproteolysis in Caenorhabditis elegans and Increases Aβ42 Generation in Human Cells Journal of Biological Chemistry ·Masayasu Okochi, Stefan Eimer, Andreas Böttcher, Ralf Baumeister, Helmut Romig, Jochen Walter, Anja Capell, Harald Steiner, Christian Haass	2000	33
16	Dependence of cerebrospinal fluid Tau protein levels on apolipoprotein E4 allele frequency in patients with Alzheimer's disease Neuroscience Letters ·Sidonie Golombowski, F. Müller‐Spahn, Helmut Romig, Klaus Mendla, Christoph Höck	1997	33
17	Expression of the type I DNA topoisomerase gene in adenovirus-5 infected human cells Nucleic Acids Research ·Helmut Romig, Arndt Richter	1990	31
18	Ultrafast and Predictive Mass Spectrometry–Based Autotaxin Assays for Label-Free Potency Screening SLAS DISCOVERY ·Tom Bretschneider, Andreas H. Luippold, Helmut Romig, Daniel Bischoff, Klaus Klinder, Paul Nicklin, Wolfgang Rist	2017	13
19	Selective CB2 receptor agonists. Part 2: Structure–activity relationship studies and optimization of proline-based compounds Bioorganic & Medicinal Chemistry Letters ·Doris Riether, Renée Zindell, Lifen Wu, Raj Betageri, James E. Jenkins, Someina Khor, Angela Berry, Eugene R. Hickey, Monika Ermann, Claudia Albrecht, Angelo Ceci, Mark J. Gemkow, N. Nagaraja, Helmut Romig, Achim Sauer, David Thomson	2014	13
20	Selective CB2 receptor agonists. Part 3: The optimization of a piperidine-based series that demonstrated efficacy in an in vivo neuropathic pain model Bioorganic & Medicinal Chemistry Letters ·Alessandra Bartolozzi, Pier F. Cirillo, Angela Berry, Eugene R. Hickey, David Thomson, Lifen Wu, Renée Zindell, Claudia Albrecht, Angelo Ceci, Mark J. Gemkow, N. Nagaraja, Helmut Romig, Achim Sauer, Doris Riether	2014	12

About Helmut Romig

Helmut Romig is a scholar working on Molecular Biology, Physiology, Oncology, Cell Biology and Pharmacology, having authored 23 papers that have together received 1.8k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (13 papers), Endoplasmic Reticulum Stress and Disease (3 papers), Genomics and Chromatin Dynamics (3 papers), Drug Transport and Resistance Mechanisms (3 papers), Cellular transport and secretion (3 papers), Cancer therapeutics and mechanisms (2 papers), Protein Structure and Dynamics (2 papers) and S100 Proteins and Annexins (2 papers). The work is most often cited by research in Physiology (1.1k citations), Cell Biology (381 citations), Pharmacology (337 citations), Aging (32 citations) and Molecular Biology (1.1k citations). Helmut Romig has collaborated with scholars based in Germany, United States and United Kingdom. Frequent co-authors include Christian Haass, Harald Steiner, Ralf Baumeister, Brigitte Pesold, Anja Capell, Martin Citron, Frank O. Fackelmayer, Melissa G. Grim, Andrea Renz and A. Richter. Their work appears in journals such as Journal of Biological Chemistry, Bioorganic & Medicinal Chemistry Letters, Nature Cell Biology, Biochemistry and SLAS DISCOVERY.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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