Hatem A. Abdel‐Aziz

7.7k citations

266 papers · 6.6k indexed · h-index 51

Organic Chemistry top 0.2%
- Synthesis and biological activity 151
- Synthesis and Characterization of Heterocyclic Compounds 60
- Synthesis and Biological Evaluation 53
- Synthesis and Catalytic Reactions 35
- Quinazolinone synthesis and applications 29
Toxicology top 0.2%
Pharmacology top 1%
Molecular Biology top 2%
- Enzyme function and inhibition 43
- Cancer therapeutics and mechanisms 32
Physical and Theoretical Chemistry top 2%
Inorganic Chemistry
- Crystal structures of chemical compounds 35

Co-authors: Wagdy M. Eldehna Claudiu T. Supuran Hany S. Ibrahim Mohamed Farès Bakr F. Abdel‐Wahab Sahar M. Abou‐Seri Alessio Nocentini Hazem A. Ghabbour
Cited by: Organic Chemistry Toxicology Pharmacology
Journals: SHILAP Revista de lepidopterología (2 papers)PLoS ONE (1 paper)Analytical Chemistry (1 paper)
Partner nations: Egypt Saudi Arabia Malaysia

In The Last Decade

Hatem A. Abdel‐Aziz

251 papers receiving 6.5k citations

Peers

Countries citing papers authored by Hatem A. Abdel‐Aziz

Since Specialization

Citations

This map shows the geographic impact of Hatem A. Abdel‐Aziz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hatem A. Abdel‐Aziz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hatem A. Abdel‐Aziz more than expected).

Fields of papers citing papers by Hatem A. Abdel‐Aziz

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hatem A. Abdel‐Aziz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hatem A. Abdel‐Aziz. The network helps show where Hatem A. Abdel‐Aziz may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Hatem A. Abdel‐Aziz, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Hatem A. Abdel‐Aziz Line = papers co-authored together Hatem A. Abdel‐Aziz links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Design, synthesis and biological evaluation of pyrazolo[3,4- b ]pyridine derivatives as dual CDK2/PIM1 inhibitors with potent anti-cancer activity and selectivity Journal of Biomolecular Structure and Dynamics ·Mahmoud S Elkotamy,Mohamed K. Elgohary,Mahmoud Abdelrahman Alkabbani,Faizah A. Binjubair,Manal M. Alanazi,Marwa Alsulaimany,Sara T. Al‐Rashood,Hazem A. Ghabbour,Hatem A. Abdel‐Aziz	2025	4
2	DprE1 inhibitors: An insight into the recent developments and synthetic approaches European Journal of Pharmaceutical Sciences ·Mai I. Shahin,Mai A Elyamani,Ahmed E. Elsawi,Ahmed T. Negmeldin,Shahenda Naguib,Heba Safwat,Hatem A. Abdel‐Aziz,Wagdy M. Eldehna	2025	2
3	Design, Synthesis, and 2D QSAR Analysis of Some Novel Pyrazolo[1,5‐a]pyrimidine Derivatives as Pim‐1 Kinase Inhibitors for the Treatment of MCF‐7 Breast Cancer Drug Development Research ·Esraa Z. Mohammed,Nehad M. El‐Dydamony,Ahmed B. M. Mehany,Samar H. Fahim,Hatem A. Abdel‐Aziz,Noha Ibrahim	2025	0
4	Discovery and characterization of phenoxyacetic acid derivatives as potential antiepileptic agents RSC Advances ·Mohamed K. Elgohary,Mahmoud S Elkotamy,Mahmoud Abdelrahman Alkabbani,Abdulrahman A. Almehizia,Ahmed M. Naglah,Mohammed H. Alqarni,Mohamed Farès,Wagdy M. Eldehna,Hatem A. Abdel‐Aziz	2025	0
5	Discovery of enaminone-linked benzofuran derivatives as dual VEGFR-2/hCA IX inhibitors exhibiting hypoxia-mediated chemosensitization RSC Medicinal Chemistry ·Wagdy M. Eldehna,Zainab M. Elsayed,Mohamed R. Elnagar,Andrea Ammara,Mahmoud S Elkotamy,Rehan Monir,Alessio Nocentini,Mohammad M. Al‐Sanea,(unknown),Haytham O. Tawfik,Hatem A. Abdel‐Aziz,Ahmed T. Negmeldin	2025	0
6	Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations Bioorganic Chemistry ·Mahmoud S Elkotamy,Mohamed K. Elgohary,Sara T. Al‐Rashood,Hadia Almahli,Wagdy M. Eldehna,Hatem A. Abdel‐Aziz	2024	25
7	Unveiling the potential of isatin-grafted phenyl-1,2,3-triazole derivatives as dual VEGFR-2/STAT-3 inhibitors: Design, synthesis and biological assessments Bioorganic Chemistry ·Heba A. Elsebaie,Maha‐Hamadien Abdulla,Zainab M. Elsayed,Moataz A. Shaldam,Haytham O. Tawfik,Samar N Morsy,Mansoor-Ali Vaali Mohammed,Thamer Bin Traiki,Eslam B. Elkaeed,Hatem A. Abdel‐Aziz,Wagdy M. Eldehna	2024	16
8	Mitigating the resistance of MCF-7 cancer cells to Doxorubicin under hypoxic conditions with novel coumarin based carbonic anhydrase IX and XII inhibitors Bioorganic Chemistry ·Hend I. Abdelaal,Abdalla R. Mohamed,Mahmoud F. Abo-Ashour,Simone Giovannuzzi,Samar H. Fahim,Hatem A. Abdel‐Aziz,Claudiu T. Supuran,Sahar M. Abou‐Seri	2024	4
9	Discovery of novel quinolin-2-one derivatives as potential GSK-3β inhibitors for treatment of Alzheimer’s disease: Pharmacophore-based design, preliminary SAR, in vitro and in vivo biological evaluation Bioorganic Chemistry ·Esraa Abdo Moustafa,Heba Abdelrasheed Allam,Marwa A. Fouad,Ahmed M. El Kerdawy,Nahed N. E. El-Sayed,Christoph Wagner,Hatem A. Abdel‐Aziz,Manal Abdel Fattah Ezzat	2024	12
10	Design, synthesis, and molecular dynamic simulations of some novel benzo[d]thiazoles with anti-virulence activity against Pseudomonas aeruginosa European Journal of Medicinal Chemistry ·Esraa Z. Mohammed,Nehad M. El‐Dydamony,Enas A. Taha,Mostafa N. Taha,Ahmed B. M. Mehany,Hatem A. Abdel‐Aziz,Rehab H. Abd El‐Aleam	2024	3
11	Spiro-fused indoline-quinazoline hybrids as smart bombs against TNF-α-mediated inflammation International Journal of Biological Macromolecules ·Mahmoud S Elkotamy,Mohamed K. Elgohary,Mahmoud Abdelrahman Alkabbani,Rofaida Salem,Wagdy M. Eldehna,Hatem A. Abdel‐Aziz	2024	7
12	Design, synthesis, and biological evaluation of dinaciclib and CAN508 hybrids as CDK inhibitors Drug Development Research ·Dana M. Odeh,Heba Abdelrasheed Allam,Fady Baselious,Walaa R. Mahmoud,Mohanad Odeh,Hany S. Ibrahim,Hatem A. Abdel‐Aziz,Eman R. Mohammed	2024	1
13	1,5-Diaryl-1,2,4-triazole Ureas as New SLC-0111 Analogues Endowed with Dual Carbonic Anhydrase and VEGFR-2 Inhibitory Activities Journal of Medicinal Chemistry ·Ahmed E. Elsawi,Mostafa M. Elbadawi,Alessio Nocentini,Hadia Almahli,Simone Giovannuzzi,Moataz A. Shaldam,Rofaida Salem,Tamer M. Ibrahim,Hatem A. Abdel‐Aziz,Claudiu T. Supuran,Wagdy M. Eldehna	2023	49
14	Enaminone-based carboxylic acids as novel non-classical carbonic anhydrases inhibitors: design, synthesis and in vitro biological assessment Journal of Enzyme Inhibition and Medicinal Chemistry ·Mahmoud F. Abo-Ashour,Hadia Almahli,Alessandro Bonardi,Amira Khalil,Tarfah Al‐Warhi,Sara T. Al‐Rashood,Hatem A. Abdel‐Aziz,Alessio Nocentini,Claudiu T. Supuran,Wagdy M. Eldehna	2022	13
15	Benzofuran-Based Carboxylic Acids as Carbonic Anhydrase Inhibitors and Antiproliferative Agents against Breast Cancer ACS Medicinal Chemistry Letters ·Wagdy M. Eldehna,Alessio Nocentini,Zainab M. Elsayed,Tarfah Al‐Warhi,Nada Aljaeed,Ohoud J. Alotaibi,Mohammad M. Al‐Sanea,Hatem A. Abdel‐Aziz,Claudiu T. Supuran	2020	55
16	Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation European Journal of Medicinal Chemistry ·Mohamed A. Said,Wagdy M. Eldehna,Alessio Nocentini,Samar H. Fahim,Alessandro Bonardi,Abdullah A. Elgazar,Vladimı́r Kryštof,Dalia H. Soliman,Hatem A. Abdel‐Aziz,Paola Gratteri,Sahar M. Abou‐Seri,Claudiu T. Supuran	2020	58
17	Novel Thiazolidinone/Thiazolo[3,2-a]Benzimidazolone-Isatin Conjugates as Apoptotic Anti-proliferative Agents Towards Breast Cancer: One-Pot Synthesis and In Vitro Biological Evaluation Molecules ·Mohamed El‐Naggar,Wagdy M. Eldehna,Hadia Almahli,Amr Elgez,Mohamed Farès,Mahmoud M. Elaasser,Hatem A. Abdel‐Aziz	2018	64
18	An improved synthesis of pyrido[2,3-d]pyrimidin-4(1H)-ones and their antimicrobial activity Organic & Biomolecular Chemistry ·Mohamed Farès,Soha R. Abd El Hadi,Radwa A. Eladwy,Aly A. Shoun,Marwa M. Abdel‐Aziz,Wagdy M. Eldehna,Hatem A. Abdel‐Aziz,Paul A. Keller	2018	23
19	Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents European Journal of Medicinal Chemistry ·Wagdy M. Eldehna,Mahmoud F. Abo-Ashour,Alessio Nocentini,Radwan El‐Haggar,Silvia Bua,Alessandro Bonardi,Sara T. Al‐Rashood,Ghada S. Hassan,Paola Gratteri,Hatem A. Abdel‐Aziz,Claudiu T. Supuran	2018	86
20	Design, Synthesis and In Vitro Antiproliferative Activity of Novel Isatin‐Quinazoline Hybrids Archiv der Pharmazie ·Mohamed Farès,Wagdy M. Eldehna,Sahar M. Abou‐Seri,Hatem A. Abdel‐Aziz,Mohamed H. Aly,Mai F. Tolba	2015	49

About Hatem A. Abdel‐Aziz

Hatem A. Abdel‐Aziz is a scholar working on Organic Chemistry, Toxicology and Inorganic Chemistry, having authored 266 papers that have together received 6.6k indexed citations. Recurring topics across this work include Synthesis and biological activity (151 papers), Synthesis and Characterization of Heterocyclic Compounds (60 papers), Synthesis and Biological Evaluation (53 papers), Enzyme function and inhibition (43 papers), Crystal structures of chemical compounds (35 papers), Synthesis and Catalytic Reactions (35 papers), Cancer therapeutics and mechanisms (32 papers) and Quinazolinone synthesis and applications (29 papers). The work is most often cited by research in Organic Chemistry (5.2k citations), Toxicology (403 citations) and Pharmacology (769 citations). Hatem A. Abdel‐Aziz has collaborated with scholars based in Egypt, Saudi Arabia and Malaysia. Frequent co-authors include Wagdy M. Eldehna, Claudiu T. Supuran, Hany S. Ibrahim, Mohamed Farès, Bakr F. Abdel‐Wahab, Sahar M. Abou‐Seri, Alessio Nocentini, Hazem A. Ghabbour, Kamal M. Dawood and Essam M. Ahmed. Their work appears in journals such as SHILAP Revista de lepidopterología, PLoS ONE and Analytical Chemistry.

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