Hans P. Merkle

16.7k total citations · 1 hit paper
189 papers, 13.4k citations indexed

About

Hans P. Merkle is a scholar working on Molecular Biology, Pharmaceutical Science and Biomaterials. According to data from OpenAlex, Hans P. Merkle has authored 189 papers receiving a total of 13.4k indexed citations (citations by other indexed papers that have themselves been cited), including 86 papers in Molecular Biology, 56 papers in Pharmaceutical Science and 49 papers in Biomaterials. Recurrent topics in Hans P. Merkle's work include RNA Interference and Gene Delivery (51 papers), Advanced Drug Delivery Systems (43 papers) and Immunotherapy and Immune Responses (32 papers). Hans P. Merkle is often cited by papers focused on RNA Interference and Gene Delivery (51 papers), Advanced Drug Delivery Systems (43 papers) and Immunotherapy and Immune Responses (32 papers). Hans P. Merkle collaborates with scholars based in Switzerland, Germany and United States. Hans P. Merkle's co-authors include Lorenz Meinel, Bruno Gander, Bruno Gander, Elke Walter, Esther Wenk, Walmir Freitas, David L. Kaplan, Pål Johansen, Sandra Hofmann and Lorenz Uebersax and has published in prestigious journals such as Angewandte Chemie International Edition, Biomaterials and Biochemistry.

In The Last Decade

Hans P. Merkle

187 papers receiving 13.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Microencapsulation by solvent extraction/evaporation: reviewing the state of the art of microsphere preparation process technology

2004 710 citations Hans P. Merkle, Bruno Gander et al. Journal of Controlled Release profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Hans P. Merkle Switzerland	66	4.8k	4.5k	3.4k	2.9k	1.7k	189	13.4k
Kazunari Akiyoshi Japan	63	4.5k 0.9×	5.9k 1.3×	3.3k 1.0×	1.4k 0.5×	1.3k 0.8×	347	14.0k
W. Mark Saltzman United States	84	7.3k 1.5×	10.3k 2.3×	6.2k 1.8×	2.4k 0.8×	1.9k 1.1×	330	23.3k
Hai‐Quan Mao United States	69	5.4k 1.1×	5.6k 1.2×	4.3k 1.3×	1.3k 0.5×	1.2k 0.7×	243	14.9k
José Luís Pedraz Spain	60	3.4k 0.7×	4.3k 0.9×	3.7k 1.1×	2.3k 0.8×	722 0.4×	387	13.7k
Jindřich Kopeček United States	77	9.0k 1.9×	7.7k 1.7×	5.1k 1.5×	1.5k 0.5×	889 0.5×	370	20.1k
Chong‐Su Cho South Korea	52	3.2k 0.7×	4.1k 0.9×	2.1k 0.6×	1.4k 0.5×	732 0.4×	273	9.4k
Niren Murthy United States	54	2.1k 0.4×	5.2k 1.1×	2.8k 0.8×	1.4k 0.5×	2.1k 1.2×	142	11.9k
Mansoor M. Amiji United States	86	9.2k 1.9×	10.1k 2.2×	6.1k 1.8×	4.0k 1.4×	2.0k 1.2×	334	24.0k
Seo Young Jeong South Korea	62	6.4k 1.3×	4.8k 1.1×	4.3k 1.3×	2.1k 0.7×	461 0.3×	195	13.3k
Yoon Yeo United States	54	3.9k 0.8×	2.3k 0.5×	3.1k 0.9×	1.6k 0.6×	513 0.3×	150	9.5k

Countries citing papers authored by Hans P. Merkle

Since Specialization

Citations

This map shows the geographic impact of Hans P. Merkle's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hans P. Merkle with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hans P. Merkle more than expected).

Fields of papers citing papers by Hans P. Merkle

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hans P. Merkle. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hans P. Merkle. The network helps show where Hans P. Merkle may publish in the future.

Co-authorship network of co-authors of Hans P. Merkle

This figure shows the co-authorship network connecting the top 25 collaborators of Hans P. Merkle. A scholar is included among the top collaborators of Hans P. Merkle based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hans P. Merkle. Hans P. Merkle is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Corthésy, Blaise, et al.. (2016). Surface-assembled poly(I:C) on PEGylated PLGA microspheres as vaccine adjuvant: APC activation and bystander cell stimulation. International Journal of Pharmaceutics. 514(1). 176–188. 19 indexed citations

Merkle, Hans P., et al.. (2007). On The Biomedical Promise of Cell Penetrating Peptides: Limits Versus Prospects. Journal of Pharmaceutical Sciences. 97(1). 144–162. 110 indexed citations

Ziegler, Urs, et al.. (2007). Differentiation Restricted Endocytosis of Cell Penetrating Peptides in MDCK Cells Corresponds with Activities of Rho-GTPases. Pharmaceutical Research. 24(4). 628–642. 45 indexed citations

Papaloïzos, Michaël, et al.. (2006). Hydrogel nerve conduits produced from alginate/chitosan complexes. Journal of Biomedical Materials Research Part A. 80A(4). 932–937. 58 indexed citations

Freitas, Sindélia, et al.. (2005). Flow-through ultrasonic emulsification combined with static micromixing for aseptic production of microspheres by solvent extraction. European Journal of Pharmaceutics and Biopharmaceutics. 61(3). 181–187. 25 indexed citations

Meinel, Lorenz, Bruno Gander, & Hans P. Merkle. (2004). Concepts and Prototypes for Formulation and Delivery of Biopharmaceuticals and in Tissue Engineering. CHIMIA International Journal for Chemistry. 58(10). 711–711.

Merkle, Hans P., et al.. (2004). Ultrasonic atomisation into reduced pressure atmosphere—envisaging aseptic spray-drying for microencapsulation. Journal of Controlled Release. 95(2). 185–195. 71 indexed citations

Wetering, Petra van de, et al.. (2003). Evaluation of pH-dependent membrane-disruptive properties of poly(acrylic acid) derived polymers. European Journal of Pharmaceutics and Biopharmaceutics. 56(2). 237–246. 70 indexed citations

Atuah, Kwame N., E. Walter, Hans P. Merkle, & H. Oya Alpar. (2003). Encapsulation of plasmid DNA in PLGA-stearylamine microspheres: A comparison of solvent evaporation and spray-drying methods. Journal of Microencapsulation. 20(3). 387–399. 17 indexed citations

10.

Walter, Elke, et al.. (2002). Compromised integrity of excised porcine intestinal epithelium obtained from the abattoir affects the outcome of in vitro particle uptake studies. European Journal of Pharmaceutical Sciences. 15(1). 39–47. 19 indexed citations

11.

Vosbeck, K., et al.. (2002). Transforming growth factor β-3 crystals as reservoirs for slow release of active TGF-β3. Journal of Controlled Release. 78(1-3). 25–34. 22 indexed citations

12.

Merkle, Hans P., et al.. (2001). Diamonds in the Rough: Protein Crystals from a Formulation Perspective. Pharmaceutical Research. 18(11). 1483–1488. 50 indexed citations

13.

Johansen, Pål, Hans P. Merkle, & Bruno Gander. (2000). Technological considerations related to the up-scaling of protein microencapsulation by spray-drying. European Journal of Pharmaceutics and Biopharmaceutics. 50(3). 413–417. 61 indexed citations

14.

Yang, Zhihong, Friedgard Julmy, Donald E. Chickering, et al.. (1999). Sustained release of heparin from polymeric particles for inhibition of human vascular smooth muscle cell proliferation. Journal of Controlled Release. 60(2-3). 269–277. 42 indexed citations

15.

Hsu, Cheng‐Pang, John M. Hilfinger, Elke Walter, et al.. (1998). Overexpression of Human Intestinal Oligopeptide Transporter in Mammalian Cells via Adenoviral Transduction. Pharmaceutical Research. 15(9). 1376–1381. 20 indexed citations

16.

Langguth, Peter, Cornelia Ottiger, Heidi Wunderli‐Allenspach, et al.. (1997). Structure-Permeation Relations of Met-enkephalin Peptide Analogues on Absorption and Secretion Mechanisms in Caco-2 Monolayers. Journal of Pharmaceutical Sciences. 86(7). 846–853. 31 indexed citations

17.

Johansen, Pål, et al.. (1996). A contribution to overcoming the problem of residual solvents in biodegradable microspheres prepared by coacervation. European Journal of Pharmaceutics and Biopharmaceutics. 42(1). 16–24. 57 indexed citations

18.

Merkle, Hans P., et al.. (1995). Dermal metabolism of topically applied drugs: Pathways and models reconsidered. Pharmaceutica Acta Helvetiae. 70(1). 3–24. 57 indexed citations

19.

Langguth, Peter, Hans P. Merkle, & Gordon L. Amidon. (1994). Oral Absorption of Peptides: The Effect of Absorption Site and Enzyme Inhibition on the Systemic Availability of Metkephamid. Pharmaceutical Research. 11(4). 528–535. 46 indexed citations

20.

Langguth, Peter, et al.. (1991). Studies on the stability of aspartame 1 specific and reproducible hplc assay for aspartame and its potential degradation products and applications to acid hydrolysis of aspartame. Pharmazie. 46(3). 188–192. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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