Guy Werlen

2.6k total citations · 1 hit paper
27 papers, 2.1k citations indexed

About

Guy Werlen is a scholar working on Molecular Biology, Immunology and Cancer Research. According to data from OpenAlex, Guy Werlen has authored 27 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 14 papers in Immunology and 6 papers in Cancer Research. Recurrent topics in Guy Werlen's work include T-cell and B-cell Immunology (12 papers), Immune Cell Function and Interaction (10 papers) and PI3K/AKT/mTOR signaling in cancer (6 papers). Guy Werlen is often cited by papers focused on T-cell and B-cell Immunology (12 papers), Immune Cell Function and Interaction (10 papers) and PI3K/AKT/mTOR signaling in cancer (6 papers). Guy Werlen collaborates with scholars based in United States, Switzerland and United Kingdom. Guy Werlen's co-authors include Ed Palmer, Barbara Hausmann, Estela Jacinto, Mark A. Daniëls, Nicholas R. J. Gascoigne, Dieter Naeher, Emma Teixeiro, Kaisa Holmberg, Jason Gill and Georg A. Holländer and has published in prestigious journals such as Nature, Science and Journal of Biological Chemistry.

In The Last Decade

Guy Werlen

26 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Hexosamine Biosynthesis Pathway: Regulation and Function

2023 99 citations Guy Werlen, Estela Jacinto et al. Genes profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Guy Werlen United States	18	1.3k	972	427	230	143	27	2.1k
Luca Simeoni Germany	24	965 0.8×	1.0k 1.1×	383 0.9×	155 0.7×	110 0.8×	49	2.1k
Anne Quillet‐Mary France	23	735 0.6×	943 1.0×	407 1.0×	159 0.7×	106 0.7×	54	1.9k
Eiji Kobayashi Japan	16	699 0.5×	792 0.8×	619 1.4×	170 0.7×	62 0.4×	39	1.6k
Sühendan Ekmekçioglu United States	28	920 0.7×	1.1k 1.1×	1.1k 2.7×	314 1.4×	109 0.8×	47	2.4k
Drell A. Bottorff Canada	13	577 0.5×	1.1k 1.1×	305 0.7×	111 0.5×	199 1.4×	19	1.7k
Marianne Broome Powell United States	21	436 0.3×	978 1.0×	563 1.3×	347 1.5×	280 2.0×	34	1.8k
Chi‐Dug Kang South Korea	29	717 0.6×	857 0.9×	931 2.2×	245 1.1×	97 0.7×	69	2.0k
Theo A. Berkhout United Kingdom	20	747 0.6×	710 0.7×	923 2.2×	197 0.9×	95 0.7×	28	1.9k
Annick Verhee Belgium	24	567 0.4×	651 0.7×	446 1.0×	86 0.4×	127 0.9×	41	1.7k
Ewen Gallagher United States	16	524 0.4×	1.3k 1.4×	463 1.1×	447 1.9×	229 1.6×	22	1.9k

Countries citing papers authored by Guy Werlen

Since Specialization

Citations

This map shows the geographic impact of Guy Werlen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Guy Werlen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Guy Werlen more than expected).

Fields of papers citing papers by Guy Werlen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Guy Werlen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Guy Werlen. The network helps show where Guy Werlen may publish in the future.

Co-authorship network of co-authors of Guy Werlen

This figure shows the co-authorship network connecting the top 25 collaborators of Guy Werlen. A scholar is included among the top collaborators of Guy Werlen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Guy Werlen. Guy Werlen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Z., Oak, et al.. (2024). Inhibition of p70 Ribosomal S6 Kinase (S6K1) Reduces Cortical Blood Flow in a Rat Model of Autism-Tuberous Sclerosis. NeuroMolecular Medicine. 26(1). 10–10. 1 indexed citations

Werlen, Guy, et al.. (2024). Food for thought: Nutrient metabolism controlling early T cell development. BioEssays. 47(1). e2400179–e2400179. 2 indexed citations

Werlen, Guy, et al.. (2023). The Hexosamine Biosynthesis Pathway: Regulation and Function. Genes. 14(4). 933–933. 99 indexed citations breakdown →

Werlen, Guy, Meiling Li, Victoria da Silva-Diz, et al.. (2022). Dietary glucosamine overcomes the defects in αβ-T cell ontogeny caused by the loss of de novo hexosamine biosynthesis. Nature Communications. 13(1). 7404–7404. 10 indexed citations

Li, Mei-Ling, et al.. (2022). The RNA-binding protein AUF1 facilitates Akt phosphorylation at the membrane. Journal of Biological Chemistry. 298(10). 102437–102437. 5 indexed citations

Moloughney, Joseph G., Peter K. Kim, Austin Chang, et al.. (2018). mTORC2 modulates the amplitude and duration of GFAT1 Ser-243 phosphorylation to maintain flux through the hexosamine pathway during starvation. Journal of Biological Chemistry. 293(42). 16464–16478. 39 indexed citations

Moloughney, Joseph G., Peter K. Kim, Sisi Zhang, et al.. (2016). mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1. Molecular Cell. 63(5). 811–826. 109 indexed citations

Oh, Won Jun, Joseph G. Moloughney, Markus A. Rüegg, et al.. (2014). Mammalian Target of Rapamycin Complex 2 Modulates αβTCR Processing and Surface Expression during Thymocyte Development. The Journal of Immunology. 193(3). 1162–1170. 21 indexed citations

Pastorino, Sandra, Erin L. Filbert, Florian J. Sulzmaier, et al.. (2010). The death effector domain protein PEA‐15 negatively regulates T‐cell receptor signaling. The FASEB Journal. 24(8). 2818–2828. 16 indexed citations

10.

Clarke, Raedun, et al.. (2009). A new function for LAT and CD8 during CD8‐mediated apoptosis that is independent of TCR signal transduction. European Journal of Immunology. 39(6). 1619–1631. 5 indexed citations

11.

Daniëls, Mark A., Emma Teixeiro, Jason Gill, et al.. (2006). Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling. Nature. 444(7120). 724–729. 459 indexed citations

12.

Lovatt, Matthew, Andrew Filby, Valentino Parravicini, et al.. (2006). Lck Regulates the Threshold of Activation in Primary T Cells, While both Lck and Fyn Contribute to the Magnitude of the Extracellular Signal-Related Kinase Response. Molecular and Cellular Biology. 26(22). 8655–8665. 95 indexed citations

13.

Werlen, Guy & Ed Palmer. (2002). The T-cell receptor signalosome: a dynamic structure with expanding complexity. Current Opinion in Immunology. 14(3). 299–305. 106 indexed citations

14.

Rosette, Caridad, Guy Werlen, Mark A. Daniëls, et al.. (2001). The Impact of Duration versus Extent of TCR Occupancy on T Cell Activation. Immunity. 15(1). 59–70. 202 indexed citations

15.

Werlen, Guy, Barbara Hausmann, & Ed Palmer. (2000). A motif in the αβ T-cell receptor controls positive selection by modulating ERK activity. Nature. 406(6794). 422–426. 164 indexed citations

16.

Luo, Z. David, Yibin Wang, Guy Werlen, et al.. (1999). Calcineurin Enhances Acetylcholinesterase mRNA Stability during C2-C12 Muscle Cell Differentiation. Molecular Pharmacology. 56(5). 886–894. 3 indexed citations

17.

Werlen, Guy. (1998). Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes. The EMBO Journal. 17(11). 3101–3111. 242 indexed citations

18.

Jacinto, Estela, Guy Werlen, & Michael Karin. (1998). Cooperation between Syk and Rac1 Leads to Synergistic JNK Activation in T Lymphocytes. Immunity. 8(1). 31–41. 117 indexed citations

19.

Slosman, D.O., et al.. (1990). Bleomycin primes monocytes-macrophages for superoxide production. European Respiratory Journal. 3(7). 772–778. 25 indexed citations

20.

Polla, Barbara S., Guy Werlen, Michel Clerget, et al.. (1989). 1,25-Dihydroxyvitamin D3 Induces Responsiveness to the Chemotactic Peptide f-Met-Leu-Phe in the Human Monocytic Line U937: Dissociation Between Calcium and Oxidative Metabolic Responses. Journal of Leukocyte Biology. 45(5). 381–388. 17 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact