Guy C. Brown

37.3k total citations · 11 hit papers
229 papers, 22.9k citations indexed

About

Guy C. Brown is a scholar working on Molecular Biology, Physiology and Neurology. According to data from OpenAlex, Guy C. Brown has authored 229 papers receiving a total of 22.9k indexed citations (citations by other indexed papers that have themselves been cited), including 86 papers in Molecular Biology, 77 papers in Physiology and 61 papers in Neurology. Recurrent topics in Guy C. Brown's work include Neuroinflammation and Neurodegeneration Mechanisms (61 papers), Mitochondrial Function and Pathology (53 papers) and Nitric Oxide and Endothelin Effects (43 papers). Guy C. Brown is often cited by papers focused on Neuroinflammation and Neurodegeneration Mechanisms (61 papers), Mitochondrial Function and Pathology (53 papers) and Nitric Oxide and Endothelin Effects (43 papers). Guy C. Brown collaborates with scholars based in United Kingdom, Lithuania and South Sudan. Guy C. Brown's co-authors include Vilmantė Borutaitė, Jonas J. Neher, Chris E. Cooper, David F. S. Rolfe, Anna Bal‐Price, Martin D. Brand, Anna Vilalta, Michael Fricker, Salvador Moncada and Urtė Neniškytė and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Neuroscience.

In The Last Decade

Guy C. Brown

226 papers receiving 22.4k citations

Hit Papers

Cellular energy utilization and molecular origin of stand... 1994 2026 2004 2015 1997 1994 2018 1998 2014 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Cellular energy utilization and molecular origin of standard metabolic rate in mammals
    1997 1.5k citations Guy C. Brown et al. profile →
  2. Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase
    1994 878 citations Guy C. Brown et al. FEBS Letters profile →
  3. Neuronal Cell Death
    2018 831 citations Vilmantė Borutaitė, Guy C. Brown et al. profile →
  4. Persistent inhibition of cell respiration by nitric oxide: Crucial role ofS-nitrosylation of mitochondrial complex I and protective action of glutathione
    1998 710 citations Guy C. Brown et al. profile →
  5. Microglial phagocytosis of live neurons
    2014 657 citations Guy C. Brown et al. profile →
  6. Inflammatory Neurodegeneration Mediated by Nitric Oxide from Activated Glia-Inhibiting Neuronal Respiration, Causing Glutamate Release and Excitotoxicity
    2001 593 citations Guy C. Brown et al. Journal of Neuroscience profile →
  7. Nitric oxide and mitochondrial respiration
    1999 574 citations Guy C. Brown Biochimica et Biophysica Acta (BBA) - Bioenergetics profile →
  8. The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance
    2008 566 citations Guy C. Brown et al. profile →
  9. Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase
    2001 520 citations Guy C. Brown Biochimica et Biophysica Acta (BBA) - Bioenergetics profile →
  10. The endotoxin hypothesis of neurodegeneration
    2019 346 citations Guy C. Brown profile →
  11. The endotoxin hypothesis of Alzheimer’s disease
    2024 60 citations Guy C. Brown et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Guy C. Brown United Kingdom 79 9.4k 7.0k 5.1k 3.5k 2.4k 229 22.9k
Paul L. Huang United States 87 10.0k 1.1× 11.8k 1.7× 2.3k 0.5× 2.9k 0.8× 3.4k 1.5× 260 31.0k
Edward J. Goetzl United States 94 13.6k 1.4× 6.2k 0.9× 1.9k 0.4× 5.8k 1.7× 3.7k 1.6× 380 26.6k
Nicolás G. Bazán United States 85 10.7k 1.1× 4.5k 0.6× 3.2k 0.6× 1.7k 0.5× 4.5k 1.9× 524 25.0k
Salvatore Cuzzocrea Italy 97 14.0k 1.5× 8.6k 1.2× 3.5k 0.7× 5.8k 1.7× 3.0k 1.3× 923 43.4k
Zoltán Ungvári United States 86 7.0k 0.7× 7.6k 1.1× 3.9k 0.8× 2.1k 0.6× 1.1k 0.5× 412 24.6k
Harald Schmidt Germany 91 9.1k 1.0× 14.2k 2.0× 1.8k 0.4× 4.4k 1.3× 3.7k 1.5× 372 29.5k
Karl‐Heinz Krause Switzerland 70 9.4k 1.0× 5.3k 0.8× 2.3k 0.4× 6.9k 2.0× 1.5k 0.6× 249 22.7k
D. Allan Butterfield United States 88 11.1k 1.2× 10.2k 1.5× 2.7k 0.5× 817 0.2× 2.5k 1.1× 285 24.2k
Nancy J. Rothwell United Kingdom 94 8.0k 0.8× 7.9k 1.1× 9.3k 1.8× 6.5k 1.9× 3.6k 1.5× 352 29.5k
Bin Liu United States 64 6.5k 0.7× 3.1k 0.4× 5.7k 1.1× 2.3k 0.7× 3.3k 1.4× 310 16.7k

Countries citing papers authored by Guy C. Brown

Since Specialization
Citations

This map shows the geographic impact of Guy C. Brown's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Guy C. Brown with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Guy C. Brown more than expected).

Fields of papers citing papers by Guy C. Brown

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Guy C. Brown. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Guy C. Brown. The network helps show where Guy C. Brown may publish in the future.

Co-authorship network of co-authors of Guy C. Brown

This figure shows the co-authorship network connecting the top 25 collaborators of Guy C. Brown. A scholar is included among the top collaborators of Guy C. Brown based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Guy C. Brown. Guy C. Brown is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Morkūnienė, Ramunė, et al.. (2025). S100A9 protein activates microglia and stimulates phagocytosis, resulting in synaptic and neuronal loss. Neurobiology of Disease. 206. 106817–106817. 4 indexed citations
2.
Brown, Guy C.. (2024). Bioenergetic myths of energy transduction in eukaryotic cells. Frontiers in Molecular Biosciences. 11. 1402910–1402910. 4 indexed citations
3.
Brown, Guy C., et al.. (2024). The microglial P2Y6 receptor as a therapeutic target for neurodegenerative diseases. Translational Neurodegeneration. 13(1). 47–47. 8 indexed citations
4.
Burkauskas, Julius, Rymantė Gleiznienė, Vilmantė Borutaitė, et al.. (2024). The links between neuroinflammation, brain structure and depressive disorder: A cross-sectional study protocol. PLoS ONE. 19(11). e0311218–e0311218.
5.
Morkūnienė, Ramunė, et al.. (2023). Extracellular tau stimulates phagocytosis of living neurons by activated microglia via Toll-like 4 receptor–NLRP3 inflammasome–caspase-1 signalling axis. Scientific Reports. 13(1). 10813–10813. 11 indexed citations
6.
Puigdellívol, Mar, et al.. (2023). P2Y 6 Receptor-Dependent Microglial Phagocytosis of Synapses during Development Regulates Synapse Density and Memory. Journal of Neuroscience. 43(48). 8090–8103. 11 indexed citations
7.
Puigdellívol, Mar, et al.. (2022). P2Y6 receptor‐dependent microglial phagocytosis of synapses mediates synaptic and memory loss in aging. Aging Cell. 22(2). e13761–e13761. 20 indexed citations
8.
Morkūnienė, Ramunė, Tomas Šneideris, Vytautas Smirnovas, et al.. (2019). Extracellular tau induces microglial phagocytosis of living neurons in cell cultures. Journal of Neurochemistry. 154(3). 316–329. 46 indexed citations
9.
Nomura, Koji, et al.. (2017). Activated Microglia Desialylate and Phagocytose Cells via Neuraminidase, Galectin-3, and Mer Tyrosine Kinase. The Journal of Immunology. 198(12). 4792–4801. 83 indexed citations
10.
11.
Brown, Guy C.. (2006). Nitric oxide and mitochondria. Frontiers in bioscience. 12(1). 1024–1024. 139 indexed citations
12.
Mander, Palwinder K., Aistė Jekabsone, & Guy C. Brown. (2006). Microglia Proliferation Is Regulated by Hydrogen Peroxide from NADPH Oxidase. The Journal of Immunology. 176(2). 1046–1052. 166 indexed citations
13.
Brown, Guy C. & Vilmantė Borutaitė. (2004). Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1658(1-2). 44–49. 283 indexed citations
14.
Brown, Guy C., et al.. (2000). Quality and cost effectiveness in health care: a unique approach.. PubMed. 19(1). 26–30. 4 indexed citations
15.
Brown, Guy C.. (1999). Nitric oxide and mitochondrial respiration. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1411(2-3). 351–369. 574 indexed citations breakdown →
16.
Kholodenko, Boris Ν., Jan B. Hoek, Hans V. Westerhoff, & Guy C. Brown. (1997). Quantification of information transfer via cellular signal transduction pathways. FEBS Letters. 414(2). 430–434. 132 indexed citations
17.
Borutaitė, Vilmantė, Vida Mildažienė, Guy C. Brown, & Martin D. Brand. (1995). Control and kinetic analysis of ischemia-damaged heart mitochondria: which parts of the oxidative phosphorylation system are affected by ischemia?. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1272(3). 154–158. 83 indexed citations
18.
Brown, Guy C., et al.. (1994). Age-specific and inter-sexual susceptibility of twospotted spider mite, Tetranychus urticae Koch, to Neozygites floridana Weiser and Muma.. Journal of the Kansas Entomological Society. 67(3). 293–296. 2 indexed citations
19.
Nobes, Catherine D., et al.. (1990). Non-ohmic proton conductance of the mitochondrial inner membrane in hepatocytes.. Journal of Biological Chemistry. 265(22). 12903–12909. 148 indexed citations
20.
Brown, Guy C., et al.. (1984). The fundus manifestations of malignant hypertension.. PubMed. 37(1). 19–25. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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