Guy A. Rutter

30.4k total citations · 5 hit papers
403 papers, 22.0k citations indexed

About

Guy A. Rutter is a scholar working on Surgery, Molecular Biology and Endocrinology, Diabetes and Metabolism. According to data from OpenAlex, Guy A. Rutter has authored 403 papers receiving a total of 22.0k indexed citations (citations by other indexed papers that have themselves been cited), including 281 papers in Surgery, 237 papers in Molecular Biology and 92 papers in Endocrinology, Diabetes and Metabolism. Recurrent topics in Guy A. Rutter's work include Pancreatic function and diabetes (271 papers), Metabolism, Diabetes, and Cancer (108 papers) and Diabetes and associated disorders (61 papers). Guy A. Rutter is often cited by papers focused on Pancreatic function and diabetes (271 papers), Metabolism, Diabetes, and Cancer (108 papers) and Diabetes and associated disorders (61 papers). Guy A. Rutter collaborates with scholars based in United Kingdom, United States and Canada. Guy A. Rutter's co-authors include Gabriela da Silva Xavier, Isabelle Leclerc, Takashi Tsuboi, Rosario Rizzuto, Edward Ainscow, Magalie A. Ravier, Anikó Váradi, Timothy J. Pullen, David J. Hodson and Elinor J. Griffiths and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Guy A. Rutter

391 papers receiving 21.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Regulation of mitochondrial ATP synthesis by calcium: Evidence for a long-term metabolic priming

1999 676 citations Guy A. Rutter, Rosario Rizzuto et al. Proceedings of the National Academy of Sciences profile →
Initiation and execution of lipotoxic ER stress in pancreatic β-cells

2008 501 citations Elisa A. Bellomo, Piero Marchetti et al. profile →
The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus

2016 480 citations Guy A. Rutter et al. profile →
Metformin activates a duodenal Ampk–dependent pathway to lower hepatic glucose production in rats

2015 327 citations Guy A. Rutter et al. profile →
Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose

2016 324 citations Ryan K. Mitchell, Jorge Ferrer et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Guy A. Rutter United Kingdom	82	12.6k	10.3k	4.7k	4.1k	2.8k	403	22.0k
Bernard Thorens Switzerland	88	14.1k 1.1×	10.4k 1.0×	8.2k 1.7×	3.7k 0.9×	1.4k 0.5×	261	28.2k
Per‐Olof Berggren Sweden	79	10.8k 0.9×	12.2k 1.2×	5.5k 1.2×	4.8k 1.2×	2.6k 0.9×	533	22.0k
Susumu Seino Japan	83	13.8k 1.1×	8.2k 0.8×	6.4k 1.4×	3.0k 0.7×	2.0k 0.7×	328	26.1k
Claes B. Wollheim Switzerland	91	15.6k 1.2×	15.0k 1.5×	6.5k 1.4×	5.4k 1.3×	4.2k 1.5×	349	26.8k
Mark A. Magnuson United States	95	16.1k 1.3×	12.3k 1.2×	5.8k 1.2×	6.4k 1.6×	2.0k 0.7×	249	26.4k
Patrik Rorsman Sweden	89	15.1k 1.2×	17.0k 1.7×	8.0k 1.7×	5.2k 1.3×	3.2k 1.2×	306	27.6k
Frances M. Ashcroft United Kingdom	78	13.6k 1.1×	10.3k 1.0×	5.9k 1.3×	3.4k 0.8×	963 0.3×	283	25.5k
Domenico Accili United States	92	18.8k 1.5×	10.0k 1.0×	6.8k 1.5×	4.9k 1.2×	2.1k 0.7×	271	31.5k
Michael B. Wheeler Canada	68	6.0k 0.5×	6.6k 0.6×	4.0k 0.8×	2.0k 0.5×	1.4k 0.5×	204	13.5k
Piero Marchetti Italy	81	7.8k 0.6×	13.6k 1.3×	7.4k 1.6×	7.3k 1.8×	2.5k 0.9×	484	23.1k

Countries citing papers authored by Guy A. Rutter

Since Specialization

Citations

This map shows the geographic impact of Guy A. Rutter's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Guy A. Rutter with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Guy A. Rutter more than expected).

Fields of papers citing papers by Guy A. Rutter

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Guy A. Rutter. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Guy A. Rutter. The network helps show where Guy A. Rutter may publish in the future.

Co-authorship network of co-authors of Guy A. Rutter

This figure shows the co-authorship network connecting the top 25 collaborators of Guy A. Rutter. A scholar is included among the top collaborators of Guy A. Rutter based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Guy A. Rutter. Guy A. Rutter is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Chabosseau, Pauline, Iris Noyman, Orna Staretz‐Chacham, et al.. (2025). Severe neonatal hypotonia due to SLC30A5 variant affecting function of ZnT5 zinc transporter. JIMD Reports. 66(1). e12465–e12465.

Deng, Yamei, Jie Zhu, Emily M. Walker, et al.. (2025). LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes. Nature Metabolism. 7(8). 1570–1592. 1 indexed citations

Ghiasi, Seyed Mojtaba, Piero Marchetti, Lorenzo Piemonti, et al.. (2024). Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells. Frontiers in Endocrinology. 15. 1359147–1359147. 2 indexed citations

Shchepinova, Maria M., Guy A. Rutter, Asuka Inoue, et al.. (2024). Engineered mini-G proteins block the internalization of cognate GPCRs and disrupt downstream intracellular signaling. Science Signaling. 17(843). eabq7038–eabq7038. 9 indexed citations

Morán, Ignasi, Amélie Bonnefond, Amna Khamis, et al.. (2024). Multiple genetic variants at the SLC30A8 locus affect local super‐enhancer activity and influence pancreatic β‐cell survival and function. The FASEB Journal. 38(8). e23610–e23610. 2 indexed citations

Bitsi, Stavroula, et al.. (2023). Divergent acute versus prolonged pharmacological GLP-1R responses in adult β cell–specific β-arrestin 2 knockout mice. Science Advances. 9(18). eadf7737–eadf7737. 20 indexed citations

Jesus, Daniel Simões de, Yi-Fang Wang, Pauline Chabosseau, et al.. (2021). Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial–mesenchymal transition in diabetes. Molecular Metabolism. 53. 101248–101248. 16 indexed citations

Pickford, Philip, Zijian Fang, Stavroula Bitsi, et al.. (2020). Signalling, trafficking and glucoregulatory properties of glucagon‐like peptide‐1 receptor agonists exendin‐4 and lixisenatide. British Journal of Pharmacology. 177(17). 3905–3923. 34 indexed citations

Baxan, Nicoleta, Lan Zhao, Isabelle Leclerc, et al.. (2020). Synthesis and in vivo behaviour of an exendin-4-based MRI probe capable of β-cell-dependent contrast enhancement in the pancreas. Dalton Transactions. 49(15). 4732–4740. 5 indexed citations

10.

Nguyen‐Tu, Marie‐Sophie, Aida Martínez-Sánchez, Isabelle Leclerc, Guy A. Rutter, & Gabriela da Silva Xavier. (2020). Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice. Diabetologia. 64(1). 129–141. 22 indexed citations

11.

Buenaventura, Teresa, Stavroula Bitsi, Thomas Burgoyne, et al.. (2019). Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells. PLoS Biology. 17(8). e3000097–e3000097. 66 indexed citations

12.

Davis, Samuel, Sunil Kumar, Yuriy Alexandrov, et al.. (2019). Convolutional neural networks for reconstruction of undersampled optical projection tomography data applied to in vivo imaging of zebrafish. Journal of Biophotonics. 12(12). e201900128–e201900128. 12 indexed citations

13.

Kleiner, Sandra, Daniel R. Gomez, Erqian Na, et al.. (2018). Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity. Proceedings of the National Academy of Sciences. 115(32). E7642–E7649. 40 indexed citations

14.

Hamilton, Alexander, Quan Zhang, Albert Salehi, et al.. (2018). Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells. Diabetes. 67(6). 1128–1139. 76 indexed citations

15.

Mitchell, Ryan K., David J. Hodson, Jorge Ferrer, et al.. (2016). Defective glucose homeostasis in mice inactivated selectively for Tcf7l2 in the adult beta cell with an Ins1-controlled Cre. Spiral (Imperial College London).

16.

Cane, Matthew C., et al.. (2015). The two pore channel TPC2 is dispensable in pancreatic β-cells for normal Ca2+ dynamics and insulin secretion. Cell Calcium. 59(1). 32–40. 26 indexed citations

17.

Sun, Gao, Gabriela da Silva Xavier, Tracy Gorman, et al.. (2015). LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemia. Molecular Metabolism. 4(4). 277–286. 22 indexed citations

18.

Hodson, David J., Elisa A. Bellomo, Stephen J. Hughes, et al.. (2013). GLP-1-regulated beta cell connectivity in intact human islets. Diabetic Medicine. 30. 17–17. 1 indexed citations

19.

Ma, Dan, Julian Hamilton‐Shield, Wendy Dean, et al.. (2004). Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM. Journal of Clinical Investigation. 114(3). 339–348. 120 indexed citations

20.

Kennedy, Helen J., et al.. (1998). Imaging glucose-induced increases in ATP in single living islet β-cells. Diabetic Medicine. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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