Grace DeSantis

2.1k citations

23 papers · 1.4k indexed · h-index 16

Impact in

Biotechnology top 2%
- Enzyme Production and Characterization
Molecular Biology top 10%
- Enzyme Catalysis and Immobilization
- Microbial Metabolic Engineering and Bioproduction
- Chemical Synthesis and Analysis
- Biochemical and Molecular Research

Papers in

Biotechnology 6
- Enzyme Production and Characterization 6
Biochemistry 4
- Amino Acid Enzymes and Metabolism 4

Co-authors: Janet Jones Chi‐Huey Wong Ian A. Wilson A. Heine J. Bryan Jones J.G. Luz Michael L. Mitchell Kelvin K. L. Wong
Journals: Journal of the American Chemical Society (6 papers)Bioorganic & Medicinal Chemistry (4 papers)Biochemistry (2 papers)Accounts of Chemical Research (1 paper)Science (1 paper)
Partner nations: Canada United States United Kingdom

In The Last Decade

Grace DeSantis

23 papers receiving 1.4k citations

Peers

Countries citing papers authored by Grace DeSantis

Since Specialization

Citations

This map shows the geographic impact of Grace DeSantis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Grace DeSantis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Grace DeSantis more than expected).

Fields of papers citing papers by Grace DeSantis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Grace DeSantis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Grace DeSantis. The network helps show where Grace DeSantis may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Grace DeSantis, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Grace DeSantis Line = papers co-authored together Grace DeSantis links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	High-Throughput Next-Generation Sequencing Respiratory Viral Panel: A Diagnostic and Epidemiologic Tool for SARS-CoV-2 and Other Viruses Viruses ·Nikhil Sahajpal, Ashis K. Mondal, M. Muhammed Niyas, Qing-Qing Li, Jiani Chen, Sudha Ananth, Pankaj Ahluwalia, S Х Ziyadullayev, Ted M. Ross, Alka Chaubey, Grace DeSantis, Gary P. Schroth, Justin Bahl, Ravindra Kolhe	2021	9
2	Optimizing blood collection, transport and storage conditions for cell free DNA increases access to prenatal testing Clinical Biochemistry ·David T. Wong, Cüneyt Akçatepe, Vach Angkachatchai, Reinhold Mueller, Grace DeSantis, Dirk van den Boom, Mathias Ehrich	2013	108
3	Engineering Hyperthermostability into a GH11 Xylanase Is Mediated by Subtle Changes to Protein Structure Journal of Biological Chemistry ·Claire Dumon, Alexander Varvak, M. A. Wall, J.E. Flint, Richard J. Lewis, Jeremy H. Lakey, Carl Morland, Peter Luginbühl, Alondra Morales, Sun Zhi-kang, Grace DeSantis, Istiqomah Istiqomah, 霍娜, Xuqiu Tan, David P. Weiner, Harry J. Gilbert	2008	105
4	Structure-Based mutagenesis approaches toward expanding the substrate specificity of d-2-Deoxyribose-5-phosphate aldolase Bioorganic & Medicinal Chemistry ·Grace DeSantis, Ibrahim Shoaib Ibrahim, David P. Clark, A. Heine, Ian A. Wilson, Chi‐Huey Wong	2003	91
5	Creation of a Productive, Highly Enantioselective Nitrilase through Gene Site Saturation Mutagenesis (GSSM) Journal of the American Chemical Society ·Grace DeSantis, Kelvin K. L. Wong, Rudolf Bültermann, Kelly Chatman, Zuolin Zhu, 丁玉玲, Hongjun Huang, Xuqiu Tan, Lisa Bibbs, Pei Chen, Keith A. Kretz, Mark J. Burk	2003	182
6	Structure-based rationalization of aldolase-catalyzed asymmetric synthesis Canadian Journal of Chemistry ·Junjie Liu, Grace DeSantis, Chi‐Huey Wong	2002	2
7	An Enzyme Library Approach to Biocatalysis: Development of Nitrilases for Enantioselective Production of Carboxylic Acid Derivatives Journal of the American Chemical Society ·Grace DeSantis, Zuolin Zhu, William A. Greenberg, Kelvin K. L. Wong, Flávia Costa Mello, Sarah R. Hanson, Rudolf Bültermann, Lawrence W. Nicholson, Cynthia L. Rand, David P. Weiner, Dan E. Robertson, Mark J. Burk	2002	190
8	Combining site-specific chemical modification with site-directed mutagenesis. Versatile strategy to move beyond structural limitations of 20 natural amino acids side chains in protein engineering. PubMed ·Grace DeSantis, J. Bryan Jones	2002	1
9	An Enzyme Library Approach to Biocatalysis: Development of Nitrilases for Enantioselective Production of Carboxylic Acid Derivatives [J. Am. Chem. Soc. 2002, 124 (31), 9024−9025]. Journal of the American Chemical Society ·Grace DeSantis, Zuolin Zhu, William A. Greenberg, Kelvin K. L. Wong, Flávia Costa Mello, Sarah R. Hanson, Rudolf Bültermann, Lawrence W. Nicholson, Cynthia L. Rand, David P. Weiner, Rhacel Parreñas, Mark J. Burk	2002	4
10	Observation of Covalent Intermediates in an Enzyme Mechanism at Atomic Resolution Science ·A. Heine, Grace DeSantis, J.G. Luz, Michael L. Mitchell, Chi‐Huey Wong, Ian A. Wilson	2001	239
11	Benzophenone boronic acid photoaffinity labeling of subtilisin CMMs to probe altered specificity Bioorganic & Medicinal Chemistry ·Grace DeSantis, Christian Paech, J. Bryan Jones	2000	5
12	Probing the altered specificity and catalytic properties of mutant subtilisin chemically modified at position S156C and S166C in the S1 pocket Bioorganic & Medicinal Chemistry ·Grace DeSantis, J. Bryan Jones	1999	7
13	The controlled introduction of multiple negative charge at single amino acid sites in subtilisin Bacillus lentus Bioorganic & Medicinal Chemistry ·Benjamin G. Davis, Xiao Shang, Grace DeSantis, R. Bott, J. Bryan Jones	1999	16
14	Modulation of Esterase and Amidase Activity of Subtilisin Bacillus lentus by Chemical Modification of Cysteine Mutants Journal of the American Chemical Society ·Erika Plettner, Grace DeSantis, Saurabh Chawla, J. Bryan Jones	1999	19
15	Chemical modification of enzymes for enhanced functionality Current Opinion in Biotechnology ·Grace DeSantis, Janet Jones	1999	227
16	Toward Tailoring the Specificity of the S₁ Pocket of Subtilisin B. lentus: Chemical Modification of Mutant Enzymes as a Strategy for Removing Specificity Limitations Biochemistry ·Grace DeSantis, Xiao Shang, J. Bryan Jones	1999	21
17	Chemical Modifications at a Single Site Can Induce Significant Shifts in the pH Profiles of a Serine Protease^† Journal of the American Chemical Society ·Grace DeSantis, J. Bryan Jones	1998	25
18	Site-Directed Mutagenesis Combined with Chemical Modification as a Strategy for Altering the Specificity of the S₁ and S₁‘ Pockets of Subtilisin Bacillus lentus Biochemistry ·Grace DeSantis, Per Berglund, Saurabh Chawla, Marvin Gold, Chinh Van Nguyen	1998	38
19	Toward Understanding and Tailoring the Specificity of Synthetically Useful Enzymes Accounts of Chemical Research ·Chinh Van Nguyen, Grace DeSantis	1998	29
20	Probing the specificity of the S1 binding site of M222 mutants of subtilisin B. lentus with boronic acid inhibitors Bioorganic & Medicinal Chemistry Letters ·Saurabh Chawla, Jaynish Tailor, Grace DeSantis, Marvin Gold, J. Bryan Jones, Colin Mitchinson, R. Bott, Thomas P. Graycar, Chung-Cheng Liu	1996	34

About Grace DeSantis

Grace DeSantis is a scholar working on Biotechnology, Biochemistry, Organic Chemistry, Molecular Biology and Oncology, having authored 23 papers that have together received 1.4k indexed citations. Recurring topics across this work include Enzyme Catalysis and Immobilization (9 papers), Enzyme Structure and Function (6 papers), Enzyme Production and Characterization (6 papers), Click Chemistry and Applications (5 papers), Amino Acid Enzymes and Metabolism (4 papers), Chemical Synthesis and Analysis (3 papers), Microbial Metabolic Engineering and Bioproduction (2 papers) and Protein purification and stability (2 papers). The work is most often cited by research in Biotechnology (212 citations), Molecular Biology (1.1k citations), Biochemistry (106 citations), Organic Chemistry (380 citations) and Inorganic Chemistry (77 citations). Grace DeSantis has collaborated with scholars based in Canada, United States and United Kingdom. Frequent co-authors include Janet Jones, Chi‐Huey Wong, Ian A. Wilson, A. Heine, J. Bryan Jones, J.G. Luz, Michael L. Mitchell, Kelvin K. L. Wong, Mark J. Burk and Zuolin Zhu. Their work appears in journals such as Journal of the American Chemical Society, Bioorganic & Medicinal Chemistry, Biochemistry, Accounts of Chemical Research and Science.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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