George K. Aghajanian

45.9k total citations · 10 hit papers
239 papers, 36.9k citations indexed

About

George K. Aghajanian is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Cognitive Neuroscience. According to data from OpenAlex, George K. Aghajanian has authored 239 papers receiving a total of 36.9k indexed citations (citations by other indexed papers that have themselves been cited), including 191 papers in Cellular and Molecular Neuroscience, 125 papers in Molecular Biology and 40 papers in Cognitive Neuroscience. Recurrent topics in George K. Aghajanian's work include Neuroscience and Neuropharmacology Research (119 papers), Neurotransmitter Receptor Influence on Behavior (109 papers) and Receptor Mechanisms and Signaling (73 papers). George K. Aghajanian is often cited by papers focused on Neuroscience and Neuropharmacology Research (119 papers), Neurotransmitter Receptor Influence on Behavior (109 papers) and Receptor Mechanisms and Signaling (73 papers). George K. Aghajanian collaborates with scholars based in United States, Japan and Spain. George K. Aghajanian's co-authors include Ronald S. Duman, Jesse M. Cedarbaum, Eric J. Nestler, Robert H. Roth, Gerard J. Marek, B.S. Bunney, Benjamin S. Bunney, Rong-Jian Liu, Cam P. VanderMaelen and Jay M. Baraban and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

George K. Aghajanian

239 papers receiving 35.5k citations

Hit Papers

mTOR-Dependent Synapse F... 1973 2026 1990 2008 2010 2016 1973 2012 1997 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
    2010 2.2k citations Nanxin Li, Boyoung Lee et al. Science profile →
  2. Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants
    2016 1.2k citations Ronald S. Duman, George K. Aghajanian et al. profile →
  3. DOPAMINERGIC NEURONS: EFFECT OF ANTIPSYCHOTIC DRUGS AND AMPHETAMINE ON SINGLE CELL ACTIVITY
    1973 1.1k citations George K. Aghajanian et al. Journal of Pharmacology and Experimental Therapeutics profile →
  4. Synaptic Dysfunction in Depression: Potential Therapeutic Targets
    2012 1.1k citations Ronald S. Duman, George K. Aghajanian Science profile →
  5. Molecular and Cellular Basis of Addiction
    1997 1.1k citations George K. Aghajanian et al. Science profile →
  6. Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure
    2011 893 citations Nanxin Li, Rong-Jian Liu et al. Biological Psychiatry profile →
  7. Inhibition of both noradrenergic and serotonergic neurons in brain by the α-adrenergic agonist clonidine
    1975 773 citations George K. Aghajanian et al. Brain Research profile →
  8. Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine
    1978 691 citations George K. Aghajanian profile →
  9. Catecholamine receptors on locus coeruleus neurons: Pharmacological characterization
    1977 489 citations Jesse M. Cedarbaum, George K. Aghajanian European Journal of Pharmacology profile →
  10. Suppression of firing activity of 5-HT neurons in the dorsal raphe by alpha-adrenoceptor antagonists
    1980 383 citations George K. Aghajanian et al. Neuropharmacology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
George K. Aghajanian United States 104 25.7k 13.1k 7.6k 5.8k 5.1k 239 36.9k
Joseph T. Coyle United States 99 25.2k 1.0× 18.9k 1.4× 7.2k 0.9× 5.0k 0.9× 3.3k 0.6× 423 44.5k
Peter W. Kalivas United States 114 37.7k 1.5× 19.7k 1.5× 11.6k 1.5× 3.0k 0.5× 2.4k 0.5× 429 46.6k
M. Hamon France 93 19.7k 0.8× 12.9k 1.0× 3.5k 0.5× 2.6k 0.5× 1.6k 0.3× 642 32.6k
Huda Akil United States 107 21.6k 0.8× 15.1k 1.2× 5.8k 0.8× 1.9k 0.3× 3.6k 0.7× 498 40.5k
Sandra E. File United Kingdom 80 15.6k 0.6× 6.6k 0.5× 7.1k 0.9× 2.4k 0.4× 2.0k 0.4× 396 28.1k
Joseph L. Price United States 93 14.7k 0.6× 4.5k 0.3× 19.9k 2.6× 2.8k 0.5× 2.3k 0.5× 179 41.9k
Anthony A. Grace United States 98 22.4k 0.9× 9.2k 0.7× 14.3k 1.9× 2.3k 0.4× 3.0k 0.6× 350 35.3k
Michel Le Moal France 93 18.9k 0.7× 7.6k 0.6× 7.1k 0.9× 1.6k 0.3× 2.1k 0.4× 355 33.4k
Rachael L. Neve United States 103 16.8k 0.7× 20.1k 1.5× 5.7k 0.7× 2.9k 0.5× 2.1k 0.4× 361 37.8k
Roy A. Wise Canada 88 23.2k 0.9× 10.5k 0.8× 10.1k 1.3× 2.2k 0.4× 766 0.2× 238 32.9k

Countries citing papers authored by George K. Aghajanian

Since Specialization
Citations

This map shows the geographic impact of George K. Aghajanian's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by George K. Aghajanian with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites George K. Aghajanian more than expected).

Fields of papers citing papers by George K. Aghajanian

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by George K. Aghajanian. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by George K. Aghajanian. The network helps show where George K. Aghajanian may publish in the future.

Co-authorship network of co-authors of George K. Aghajanian

This figure shows the co-authorship network connecting the top 25 collaborators of George K. Aghajanian. A scholar is included among the top collaborators of George K. Aghajanian based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with George K. Aghajanian. George K. Aghajanian is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Shinohara, Ryota, George K. Aghajanian, & Chadi G. Abdallah. (2020). Neurobiology of the Rapid-Acting Antidepressant Effects of Ketamine: Impact and Opportunities. Biological Psychiatry. 90(2). 85–95. 36 indexed citations
2.
Duman, Ronald S. & George K. Aghajanian. (2013). Neurobiology of Rapid Acting Antidepressants: Role of BDNF and GSK-3β. Neuropsychopharmacology. 39(1). 233–233. 29 indexed citations
3.
Duman, Ronald S. & George K. Aghajanian. (2012). Synaptic Dysfunction in Depression: Potential Therapeutic Targets. Science. 338(6103). 68–72. 1133 indexed citations breakdown →
4.
Liu, Rong-Jian, Francis S. Lee, Xiaoyuan Li, et al.. (2011). Brain-Derived Neurotrophic Factor Val66Met Allele Impairs Basal and Ketamine-Stimulated Synaptogenesis in Prefrontal Cortex. Biological Psychiatry. 71(11). 996–1005. 335 indexed citations
5.
Li, Nanxin, Boyoung Lee, Rongjian Liu, et al.. (2010). mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists. Science. 329(5994). 959–964. 2240 indexed citations breakdown →
6.
Weisstaub, Noelia, Ming‐Ming Zhou, Alena Lira, et al.. (2006). Cortical 5-HT 2A Receptor Signaling Modulates Anxiety-Like Behaviors in Mice. Science. 313(5786). 536–540. 328 indexed citations
7.
Lambe, Evelyn K., Marina R. Picciotto, & George K. Aghajanian. (2003). Nicotine Induces Glutamate Release from Thalamocortical Terminals in Prefrontal Cortex. Neuropsychopharmacology. 28(2). 216–225. 219 indexed citations
8.
Jolas, Thierry & George K. Aghajanian. (1997). Opioids suppress spontaneous and NMDA-induced inhibitory postsynaptic currents in the dorsal raphe nucleus of the rat in vitro. Brain Research. 755(2). 229–245. 151 indexed citations
9.
Marek, Gerard J. & George K. Aghajanian. (1996). α1B-Adrenoceptor-mediated excitation of piriform cortical interneurons. European Journal of Pharmacology. 305(1-3). 95–100. 30 indexed citations
10.
Rasmussen, Kurt, John H. Krystal, & George K. Aghajanian. (1991). Excitatory amino acids and morphine withdrawal: differential effects of central and peripheral kynurenic acid administration. Psychopharmacology. 105(4). 508–512. 64 indexed citations
11.
Rasmussen, Kurt & George K. Aghajanian. (1989). Failure to block responses of locus coeruleus neurons to somatosensory stimuli by destruction of two major afferent nuclei. Synapse. 4(2). 162–164. 27 indexed citations
12.
Kehne, John H., James V. Cassella, George K. Aghajanian, John F. Tallman, & Michael T. Davis. (1987). Pertussis toxin or 8-bromo-cAMP block inhibition of the acoustic startle response by the α2-adrenergic agonist ST-91. Brain Research. 406(1-2). 87–92. 6 indexed citations
13.
McCall, Robert B. & George K. Aghajanian. (1979). Denervation supersensitivity to serotonin in the facial nucleus. Neuroscience. 4(10). 1501–1510. 32 indexed citations
14.
Wang, Rex Y. & George K. Aghajanian. (1977). Recording of single unit activity during electrical stimulation and microiontophoresis: A method of minimizing stimulus artifacts. Electroencephalography and Clinical Neurophysiology. 43(3). 434–437. 16 indexed citations
15.
Aghajanian, George K., et al.. (1977). Evidence for norepinephrine-mediated collateral inhibition of locus coeruleus neurons. Brain Research. 136(3). 570–577. 406 indexed citations
16.
17.
Haigler, Henry J. & George K. Aghajanian. (1974). LYSERGIC ACID DIETHYLAMIDE AND SEROTONIN: A COMPARISON OF EFFECTS ON SEROTONERGIC NEURONS AND NEURONS RECEIVING A SEROTONERGIC INPUT. Journal of Pharmacology and Experimental Therapeutics. 188(3). 688–699. 264 indexed citations
18.
Sheard, M.H., A.J. Zolovick, & George K. Aghajanian. (1972). Raphe neurons: effect of tricyclic antidepressant drugs. Brain Research. 43(2). 690–694. 130 indexed citations
19.
Clark, William G., et al.. (1970). Principles of psychopharmacology : a textbook for physicians, medical students, and behavioral scientists. Biblioteca Digital (Real Academia Nacional de Medicina). 2 indexed citations
20.
Sheard, M.H. & George K. Aghajanian. (1970). Neuronally activated metabolism of brain serotonin: Effect of lithium. Life Sciences. 9(5). 285–290. 76 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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