Francesca Semplici

1.9k total citations · 1 hit paper
17 papers, 1.5k citations indexed

About

Francesca Semplici is a scholar working on Surgery, Molecular Biology and Genetics. According to data from OpenAlex, Francesca Semplici has authored 17 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Surgery, 9 papers in Molecular Biology and 8 papers in Genetics. Recurrent topics in Francesca Semplici's work include Pancreatic function and diabetes (9 papers), Metabolism, Diabetes, and Cancer (5 papers) and Diabetes and associated disorders (4 papers). Francesca Semplici is often cited by papers focused on Pancreatic function and diabetes (9 papers), Metabolism, Diabetes, and Cancer (5 papers) and Diabetes and associated disorders (4 papers). Francesca Semplici collaborates with scholars based in United Kingdom, Italy and United States. Francesca Semplici's co-authors include Guy A. Rutter, Sandra Mazzoli, Flavio Meggio, Lorenzo A. Pinna, Maria Luisa Villa, Francesco Mazzotta, Francesca Meacci, Mara Biasin, Salvatore Oliviero and Mario Clerici and has published in prestigious journals such as Journal of Biological Chemistry, Nature Medicine and PLoS ONE.

In The Last Decade

Francesca Semplici

17 papers receiving 1.4k citations

Hit Papers

Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose 2016 2026 2019 2022 2016 100 200 300
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose
    2016 324 citations Natalie R. Johnston, Ryan K. Mitchell et al. Cell Metabolism profile →

Peers

Francesca Semplici
Rebecca Ashfield United Kingdom
John L. Foster United States
Ying Fu United States
Karin Dott France
Dmitri Kazmin United States
Sharon C. Cunningham Australia
Suzanne K. Beckner United States
Stephen W. Rothwell United States
Kathleen Sue Cook United States
Sandra Marchese Johnson United States
Rebecca Ashfield United Kingdom
Francesca Semplici
Citations per year, relative to Francesca Semplici Francesca Semplici (= 1×) peers Rebecca Ashfield

Countries citing papers authored by Francesca Semplici

Since Specialization
Citations

This map shows the geographic impact of Francesca Semplici's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Francesca Semplici with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Francesca Semplici more than expected).

Fields of papers citing papers by Francesca Semplici

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Francesca Semplici. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Francesca Semplici. The network helps show where Francesca Semplici may publish in the future.

Co-authorship network of co-authors of Francesca Semplici

This figure shows the co-authorship network connecting the top 25 collaborators of Francesca Semplici. A scholar is included among the top collaborators of Francesca Semplici based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Francesca Semplici. Francesca Semplici is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

17 of 17 papers shown
1.
Georgiadou, Eleni, Elizabeth Haythorne, Matthew T. Dickerson, et al.. (2020). The pore-forming subunit MCU of the mitochondrial Ca2+ uniporter is required for normal glucose-stimulated insulin secretion in vitro and in vivo in mice. Diabetologia. 63(7). 1368–1381. 35 indexed citations
2.
Schiff, Elena, Matthew Frampton, Francesca Semplici, et al.. (2018). Rare coding variant analysis in a large cohort of Ashkenazi Jewish families with inflammatory bowel disease. Human Genetics. 137(9). 723–734. 7 indexed citations
3.
Schiff, Elena, Matthew Frampton, Francesca Semplici, et al.. (2018). A New Look at Familial Risk of Inflammatory Bowel Disease in the Ashkenazi Jewish Population. Digestive Diseases and Sciences. 63(11). 3049–3057. 10 indexed citations
4.
Johnston, Natalie R., Ryan K. Mitchell, Elizabeth Haythorne, et al.. (2016). Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose. Cell Metabolism. 24(3). 389–401. 324 indexed citations breakdown →
5.
Semplici, Francesca, Anna Ramne, Anna E. Marley, et al.. (2016). Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production. Diabetologia. 59(9). 1938–1947. 12 indexed citations
6.
Hodson, David J., Ryan K. Mitchell, Lorella Marselli, et al.. (2014). ADCY5 Couples Glucose to Insulin Secretion in Human Islets. Diabetes. 63(9). 3009–3021. 112 indexed citations
7.
Tarasov, Andrei I., Francesca Semplici, Daliang Li, et al.. (2012). Frequency-dependent mitochondrial Ca2+ accumulation regulates ATP synthesis in pancreatic β cells. Pflügers Archiv - European Journal of Physiology. 465(4). 543–554. 69 indexed citations
8.
Tarasov, Andrei I., Francesca Semplici, Magalie A. Ravier, et al.. (2012). The Mitochondrial Ca2+ Uniporter MCU Is Essential for Glucose-Induced ATP Increases in Pancreatic β-Cells. PLoS ONE. 7(7). e39722–e39722. 143 indexed citations
9.
Semplici, Francesca, Martine Vaxillaire, Sarah Fogarty, et al.. (2011). Human Mutation within Per-Arnt-Sim (PAS) Domain-containing Protein Kinase (PASK) Causes Basal Insulin Hypersecretion. Journal of Biological Chemistry. 286(51). 44005–44014. 19 indexed citations
10.
Xavier, Gabriela da Silva, Francesca Semplici, Huai‐Xiang Hao, et al.. (2010). Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization. Biochemical and Biophysical Research Communications. 399(2). 155–161. 25 indexed citations
11.
Hao, Huai‐Xiang, et al.. (2006). Regulation by Per-Arnt-Sim (PAS) kinase of pancreatic duodenal homeobox-1 nuclear import in pancreatic β-cells. Biochemical Society Transactions. 34(5). 791–793. 27 indexed citations
12.
Semplici, Francesca, Flavio Meggio, Lorenzo A. Pinna, & Salvatore Oliviero. (2002). CK2-dependent phosphorylation of the E2 ubiquitin conjugating enzyme UBC3B induces its interaction with β-TrCP and enhances β-catenin degradation. Oncogene. 21(25). 3978–3987. 43 indexed citations
13.
Moretti, Silvia, Alessandra Chiarugi, Francesca Semplici, et al.. (2001). Serum imbalance of cytokines in melanoma patients. Melanoma Research. 11(4). 395–399. 32 indexed citations
14.
Mazzoli, Sandra, Lucia Lopalco, Daria Trabattoni, et al.. (1999). Human Immunodeficiency Virus (HIV)–Specific IgA and HIV Neutralizing Activity in the Serum of Exposed Seronegative Partners of HIV‐Seropositive Persons. The Journal of Infectious Diseases. 180(3). 871–875. 114 indexed citations
15.
Orlandini, Maurizio, et al.. (1998). Protein Kinase CK2α′ Is Induced by Serum as a Delayed Early Gene and Cooperates with Ha-ras in Fibroblast Transformation. Journal of Biological Chemistry. 273(33). 21291–21297. 111 indexed citations
16.
Mazzoli, Sandra, et al.. (1998). Chlamydia pneumoniae antibody response in patients with acute myocardial infarction and their follow-up. American Heart Journal. 135(1). 15–20. 49 indexed citations
17.
Mazzoli, Sandra, Sergio Lo Caputo, Stefania Piconi, et al.. (1997). HIV-specific mucosal and cellular immunity in HIV-seronegative partners of HIV-seropositive individuals. Nature Medicine. 3(11). 1250–1257. 341 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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