Fangrui Wu

1.8k total citations · 1 hit paper
24 papers, 1.5k citations indexed

About

Fangrui Wu is a scholar working on Molecular Biology, Pharmacology and Public Health, Environmental and Occupational Health. According to data from OpenAlex, Fangrui Wu has authored 24 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Molecular Biology, 4 papers in Pharmacology and 4 papers in Public Health, Environmental and Occupational Health. Recurrent topics in Fangrui Wu's work include Epigenetics and DNA Methylation (8 papers), Cancer-related gene regulation (6 papers) and Protein Degradation and Inhibitors (5 papers). Fangrui Wu is often cited by papers focused on Epigenetics and DNA Methylation (8 papers), Cancer-related gene regulation (6 papers) and Protein Degradation and Inhibitors (5 papers). Fangrui Wu collaborates with scholars based in United States, China and Germany. Fangrui Wu's co-authors include Joachim Stöckigt, Andrey P. Antonchick, Herbert Waldmann, Yongcheng Song, Jingyu Wu, Yuan Yao, Chao Zhou, Liping Wei, Zizhen Feng and Shenyou Nie and has published in prestigious journals such as Journal of the American Chemical Society, Angewandte Chemie International Edition and PLoS ONE.

In The Last Decade

Fangrui Wu

23 papers receiving 1.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Pictet–Spengler Reaction in Nature and in Organic Chemistry

2011 615 citations Joachim Stöckigt, Andrey P. Antonchick et al. Angewandte Chemie International Edition profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Fangrui Wu United States	16	763	749	189	186	160	24	1.5k
Maria Chrzanowska Poland	15	293 0.4×	1.2k 1.6×	121 0.6×	397 2.1×	153 1.0×	62	1.6k
Sivaraman Dandapani United States	19	928 1.2×	914 1.2×	32 0.2×	136 0.7×	121 0.8×	54	1.7k
Gregory A. Reichard United States	19	542 0.7×	601 0.8×	191 1.0×	22 0.1×	126 0.8×	37	1.4k
Brigitte Baldeyrou France	23	710 0.9×	749 1.0×	47 0.2×	75 0.4×	136 0.8×	42	1.3k
Zhu‐Jun Yao China	25	634 0.8×	1.3k 1.7×	86 0.5×	54 0.3×	193 1.2×	96	1.8k
Niamh M. O’Boyle Ireland	20	473 0.6×	825 1.1×	58 0.3×	120 0.6×	93 0.6×	48	1.3k
Soo S. Ko United States	20	561 0.7×	841 1.1×	89 0.5×	43 0.2×	93 0.6×	32	1.5k
Chang Yong Hong South Korea	20	428 0.6×	688 0.9×	99 0.5×	113 0.6×	224 1.4×	39	1.3k
Randall W. Hungate United States	22	643 0.8×	748 1.0×	47 0.2×	120 0.6×	109 0.7×	51	1.4k

Countries citing papers authored by Fangrui Wu

Since Specialization

Citations

This map shows the geographic impact of Fangrui Wu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Fangrui Wu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Fangrui Wu more than expected).

Fields of papers citing papers by Fangrui Wu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Fangrui Wu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Fangrui Wu. The network helps show where Fangrui Wu may publish in the future.

Co-authorship network of co-authors of Fangrui Wu

This figure shows the co-authorship network connecting the top 25 collaborators of Fangrui Wu. A scholar is included among the top collaborators of Fangrui Wu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Fangrui Wu. Fangrui Wu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Li, Xin, Xiaowei Wu, Shenyou Nie, et al.. (2023). Discovery, Structure–Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein–Protein Interactions between AF9/ENL and AF4 or DOT1L. Cancers. 15(21). 5283–5283. 2 indexed citations

Li, Xin, Yuan Yao, Fangrui Wu, & Yongcheng Song. (2022). A proteolysis-targeting chimera molecule selectively degrades ENL and inhibits malignant gene expression and tumor growth. Journal of Hematology & Oncology. 15(1). 41–41. 21 indexed citations

Nie, Shenyou, Fangrui Wu, Jingyu Wu, et al.. (2022). Structure-activity relationship and antitumor activity of 1,4-pyrazine-containing inhibitors of histone acetyltransferases P300/CBP. European Journal of Medicinal Chemistry. 237. 114407–114407. 7 indexed citations

Nie, Shenyou, Jidong Zhao, Xiaowei Wu, et al.. (2021). Synthesis, structure-activity relationship and antiviral activity of indole-containing inhibitors of Flavivirus NS2B-NS3 protease. European Journal of Medicinal Chemistry. 225. 113767–113767. 26 indexed citations

Wu, Fangrui, Shenyou Nie, Yuan Yao, et al.. (2021). Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth. Theranostics. 11(17). 8172–8184. 23 indexed citations

Gao, Yujing, Lijia Chen, Yali Han, et al.. (2020). Acetylation of histone H3K27 signals the transcriptional elongation for estrogen receptor alpha. Communications Biology. 3(1). 165–165. 30 indexed citations

Wu, Fangrui, Yuanda Hua, Salma Kaochar, et al.. (2020). Discovery, Structure–Activity Relationship, and Biological Activity of Histone-Competitive Inhibitors of Histone Acetyltransferases P300/CBP. Journal of Medicinal Chemistry. 63(9). 4716–4731. 25 indexed citations

Wu, Fangrui, et al.. (2019). Thermodynamic investigation of DNA-binding affinity of wild-type and mutant transcription factor RUNX1. PLoS ONE. 14(5). e0216203–e0216203. 1 indexed citations

Wen, Yefei, Yuan Yao, Fengju Chen, et al.. (2018). Glucocorticoids Inhibit Oncogenic RUNX1-ETO in Acute Myeloid Leukemia with Chromosome Translocation t(8;21). Theranostics. 8(8). 2189–2201. 11 indexed citations

10.

Wu, Fangrui, Gang Cheng, Yuan Yao, et al.. (2018). Inhibition of Mutated Isocitrate Dehydrogenase 1 in Cancer. Medicinal Chemistry. 14(7). 715–724. 6 indexed citations

11.

Zhou, Chao, et al.. (2017). Structure activity relationship and modeling studies of inhibitors of lysine specific demethylase 1. PLoS ONE. 12(2). e0170301–e0170301. 12 indexed citations

12.

Song, Yongcheng, Fangrui Wu, & Jingyu Wu. (2016). Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives. Journal of Hematology & Oncology. 9(1). 49–49. 116 indexed citations

13.

Feng, Zizhen, Yuan Yao, Chao Zhou, et al.. (2016). Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia. Journal of Hematology & Oncology. 9(1). 24–24. 84 indexed citations

14.

Wu, Fangrui, et al.. (2015). Sarpagan-Ajmalan-Type Indoles. PubMed. 76. 1–61. 14 indexed citations

15.

Wu, Fangrui, Baisong Zheng, Mari Kogiso, et al.. (2015). Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds. Journal of Medicinal Chemistry. 58(17). 6899–6908. 63 indexed citations

16.

Zhu, Huajian, Fangrui Wu, Chitra Rajendran, et al.. (2015). Using Strictosidine Synthase to Prepare Novel Alkaloids. Current Medicinal Chemistry. 22(15). 1880–1888. 16 indexed citations

17.

Wu, Fangrui, Huajian Zhu, Lianli Sun, et al.. (2012). Correction to Scaffold Tailoring by a Newly Detected Pictet–Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework. Journal of the American Chemical Society. 134(12). 5716–5716.

18.

Stöckigt, Joachim, Andrey P. Antonchick, Fangrui Wu, & Herbert Waldmann. (2011). The Pictet–Spengler Reaction in Nature and in Organic Chemistry. Angewandte Chemie International Edition. 50(37). 8538–8564. 615 indexed citations breakdown →

19.

Wu, Fangrui, Huajian Zhu, Lianli Sun, et al.. (2011). Scaffold Tailoring by a Newly Detected Pictet–Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework. Journal of the American Chemical Society. 134(3). 1498–1500. 46 indexed citations

20.

Stöckigt, Joachim, Andrey P. Antonchick, Fangrui Wu, & Herbert Waldmann. (2011). Die Pictet‐Spengler‐Reaktion in der Natur und der organischen Chemie. Angewandte Chemie. 123(37). 8692–8719. 144 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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