Ernest J. McEachern

2.2k total citations · 1 hit paper
25 papers, 1.4k citations indexed

About

Ernest J. McEachern is a scholar working on Organic Chemistry, Molecular Biology and Virology. According to data from OpenAlex, Ernest J. McEachern has authored 25 papers receiving a total of 1.4k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Organic Chemistry, 11 papers in Molecular Biology and 3 papers in Virology. Recurrent topics in Ernest J. McEachern's work include Synthetic Organic Chemistry Methods (6 papers), Asymmetric Synthesis and Catalysis (6 papers) and Carbohydrate Chemistry and Synthesis (5 papers). Ernest J. McEachern is often cited by papers focused on Synthetic Organic Chemistry Methods (6 papers), Asymmetric Synthesis and Catalysis (6 papers) and Carbohydrate Chemistry and Synthesis (5 papers). Ernest J. McEachern collaborates with scholars based in Canada, United States and Belgium. Ernest J. McEachern's co-authors include Barry M. Trost, David J. Vocadlo, Scott A. Yuzwa, Xiaoyang Shan, G.J. Davies, Keith A. Stubbs, Yuan He, Julia Heinonen, Rebecca J. Dennis and Garrett E. Whitworth and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Medicinal Chemistry and The Journal of Organic Chemistry.

In The Last Decade

Ernest J. McEachern

23 papers receiving 1.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

2008 553 citations Scott A. Yuzwa, Matthew S. Macauley et al. Nature Chemical Biology profile →

Peers

Countries citing papers authored by Ernest J. McEachern

Since Specialization

Citations

This map shows the geographic impact of Ernest J. McEachern's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ernest J. McEachern with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ernest J. McEachern more than expected).

Fields of papers citing papers by Ernest J. McEachern

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ernest J. McEachern. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ernest J. McEachern. The network helps show where Ernest J. McEachern may publish in the future.

Co-authorship network of co-authors of Ernest J. McEachern

This figure shows the co-authorship network connecting the top 25 collaborators of Ernest J. McEachern. A scholar is included among the top collaborators of Ernest J. McEachern based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ernest J. McEachern. Ernest J. McEachern is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Analysis of transition state mimicry by tight binding aminothiazoline inhibitors provides insight into catalysis by human O-GlcNAcase 2016 ·Chemical Science ·(unknown), Julia Heinonen, Keith A. Stubbs, Christian Roth, Yuan He, Andrew J. Bennet, Ernest J. McEachern, G.J. Davies, David J. Vocadlo	30
2	Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms 2015 ·Acta Crystallographica Section D Biological Crystallography ·S. Kolappan, David L. Shen, Renée Mosi, Jianyu Sun, Ernest J. McEachern, David J. Vocadlo, Lisa Craig	56
3	Pharmacological inhibition of O-GlcNAcase (OGA) prevents cognitive decline and amyloid plaque formation in bigenic tau/APP mutant mice 2014 ·Molecular Neurodegeneration ·Scott A. Yuzwa, Xiaoyang Shan, Bryan A. Jones, (unknown), (unknown), Xiaojing Li, Yanping Zhu, Ernest J. McEachern, Michael Silverman, Neil V. Watson, Cheng‐Xin Gong, David J. Vocadlo	116
4	Design of novel CXCR4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication 2011 ·Bioorganic & Medicinal Chemistry Letters ·Renato T. Skerlj, Gary Bridger, Ernest J. McEachern, Curtis Harwig, Christopher R. Smith, (unknown), D. R. VEALE, Helen S. Yee, (unknown), (unknown), (unknown), Ian R. Baird, Yongbao Zhu, (unknown), Wen Yang, Michael Sartori, Dana Huskens, Erik De Clercq, Dominique Schols	17
5	Synthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication 2010 ·Bioorganic & Medicinal Chemistry Letters ·Renato T. Skerlj, Gary Bridger, Ernest J. McEachern, Curtis Harwig, Christopher R. Smith, (unknown), D. R. VEALE, Helen S. Yee, Jason Crawford, (unknown), (unknown), Wen Yang, Yongbao Zhu, (unknown), (unknown), (unknown), Dana Huskens, Erik De Clercq, Dominique Schols	30
6	Discovery of Novel Small Molecule Orally Bioavailable C−X−C Chemokine Receptor 4 Antagonists That Are Potent Inhibitors of T-Tropic (X4) HIV-1 Replication 2010 ·Journal of Medicinal Chemistry ·Renato T. Skerlj, Gary Bridger, (unknown), Ernest J. McEachern, Jason Crawford, Yuanxi Zhou, (unknown), (unknown), (unknown), D. R. VEALE, (unknown), Curtis Harwig, Sigrid Hatse, Katrien Princen, Erik De Clercq, Dominique Schols	99
7	A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo breakdown → 2008 ·Nature Chemical Biology ·Scott A. Yuzwa, Matthew S. Macauley, Julia Heinonen, Xiaoyang Shan, Rebecca J. Dennis, Yuan He, Garrett E. Whitworth, Keith A. Stubbs, Ernest J. McEachern, G.J. Davies, David J. Vocadlo	553
8	AMD070, a CXCR4 Chemokine Receptor Antagonist: Practical Large-Scale Laboratory Synthesis 2008 ·Organic Process Research & Development ·Jason Crawford, Gang Chen, David T. Gauthier, (unknown), (unknown), Ian R. Baird, Ernest J. McEachern, (unknown), Curtis Harwig, (unknown), Renato T. Skerlj, Gary Bridger	29
9	Facile Preparation of Substituted Benz- imidazole-2-carboxylates 2006 ·Heterocycles ·Ernest J. McEachern, Yongbao Zhu, (unknown)	1
10	Asymmetric Synthesis of Oxygen Heterocycles via Pd‐Catalyzed Dynamic Kinetic Asymmetric Transformations: Application to Nucleosides 2003 ·Chemistry - A European Journal ·Barry M. Trost, Brian S. Brown, Ernest J. McEachern, Oliver Kühn	45
11	Convenient Synthesis of 5,6,7,8-Tetrahydroquinolin-8-ylamine and 6,7-Dihydro-5H-quinolin-8-one 2003 ·Synthetic Communications ·Ernest J. McEachern, Wen Yang, (unknown), Renato T. Skerlj, Gary Bridger	7
12	Enzymatic Resolution of Bicyclic 1-Heteroarylamines Using Candida antarctica Lipase B 2003 ·The Journal of Organic Chemistry ·(unknown), Ernest J. McEachern, Ian R. Baird, Renato T. Skerlj, Gary Bridger	49
13	Trifunctional Reagents in Organic Synthesis: Sequential, Chemoselective Reactions Leading to the Preparation of Structurally Novel Tricycles 2000 ·Synlett ·Edward Piers, Ernest J. McEachern	1
14	Inorganic Carbonates as Nucleophiles for the Asymmetric Synthesis of Vinylglycidols 1999 ·Journal of the American Chemical Society ·Barry M. Trost, Ernest J. McEachern	54
15	A Two-Component Catalyst System for Asymmetric Allylic Alkylations with Alcohol Pronucleophiles 1998 ·Journal of the American Chemical Society ·Barry M. Trost, Ernest J. McEachern, F. Dean Toste	128
16	Intermolecular homocoupling of alkenyltrimethylstannane functions mediated by CuCl: Preparation of functionalized conjugated diene and tetraene systems 1998 ·Tetrahedron ·Edward Piers, (unknown), (unknown), Ernest J. McEachern	24
17	Copper(I) chloride-mediated oxidative coupling of alkenyltrialkylstannyl functions: efficient stereocontrolled syntheses of uniquely functionalized conjugated diene systems 1997 ·Canadian Journal of Chemistry ·Edward Piers, Ernest J. McEachern, Miguel A. Romero, (unknown)	15
18	Intermolecular copper(I) chloride-mediated coupling of alkenyltrialkylstannane functions: A convenient synthesis of conjugated diene systems 1996 ·Tetrahedron Letters ·Edward Piers, Ernest J. McEachern, Miguel A. Romero	33
19	ChemInform Abstract: Intramolecular Michael Additions: Copper(I) Chloride‐Mediated Conjugate Addition of Vinyltrimethylstannane Functions to α,. beta.‐Unsaturated Ketones. 1995 ·ChemInform ·Edward Piers, Ernest J. McEachern, (unknown)	1
20	Intramolecular Michael Additions: Copper(I) Chloride-Mediated Conjugate Addition of Vinyltrimethylstannane Functions to .alpha.,.beta.-Unsaturated Ketones 1995 ·The Journal of Organic Chemistry ·Edward Piers, Ernest J. McEachern, Patricia Burns	21

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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