Edward E. Knaus

7.5k total citations · 1 hit paper
339 papers, 6.1k citations indexed

About

Edward E. Knaus is a scholar working on Organic Chemistry, Molecular Biology and Pharmacology. According to data from OpenAlex, Edward E. Knaus has authored 339 papers receiving a total of 6.1k indexed citations (citations by other indexed papers that have themselves been cited), including 219 papers in Organic Chemistry, 115 papers in Molecular Biology and 82 papers in Pharmacology. Recurrent topics in Edward E. Knaus's work include Inflammatory mediators and NSAID effects (71 papers), Synthesis and Biological Evaluation (69 papers) and Synthesis and biological activity (44 papers). Edward E. Knaus is often cited by papers focused on Inflammatory mediators and NSAID effects (71 papers), Synthesis and Biological Evaluation (69 papers) and Synthesis and biological activity (44 papers). Edward E. Knaus collaborates with scholars based in Canada, United States and Belgium. Edward E. Knaus's co-authors include Praveen P. N. Rao, Leonard I. Wiebe, Carlos Velázquez, Amgad G. Habeeb, Khaled R.A. Abdellatif, Morshed Alam Chowdhury, Ying Dong, Qiao‐Hong Chen, Zhangjian Huang and Mavanur R. Suresh and has published in prestigious journals such as The Journal of Physiology, Advanced Drug Delivery Reviews and Journal of Medicinal Chemistry.

In The Last Decade

Edward E. Knaus

329 papers receiving 5.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Evolution of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Cyclooxygenase (COX) Inhibition and Beyond

2008 603 citations Praveen P. N. Rao, Edward E. Knaus Journal of Pharmacy & Pharmaceutical Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Edward E. Knaus Canada	38	3.7k	1.7k	1.6k	405	402	339	6.1k
Amit S. Kalgutkar United States	51	2.4k 0.7×	2.0k 1.2×	3.0k 1.8×	236 0.6×	557 1.4×	148	8.3k
William C. Stallings United States	27	1.6k 0.4×	1.5k 0.9×	1.8k 1.1×	141 0.3×	374 0.9×	66	5.1k
Anders Hallberg Sweden	58	6.5k 1.8×	478 0.3×	3.7k 2.3×	719 1.8×	289 0.7×	287	11.2k
Carlos Alberto Manssour Fraga Brazil	41	5.2k 1.4×	987 0.6×	2.8k 1.7×	195 0.5×	202 0.5×	243	8.3k
Walter A. Szarek Canada	36	2.5k 0.7×	675 0.4×	3.1k 1.9×	106 0.3×	303 0.8×	286	5.3k
Byron H. Arison United States	40	1.4k 0.4×	880 0.5×	2.4k 1.5×	303 0.7×	368 0.9×	191	5.5k
Wolfgang Pfleiderer Germany	39	3.4k 0.9×	330 0.2×	4.3k 2.6×	841 2.1×	372 0.9×	581	7.7k
John A. Porco United States	62	8.4k 2.3×	1.6k 1.0×	4.9k 3.0×	177 0.4×	594 1.5×	248	13.3k
Afshin Zarghi Iran	35	2.0k 0.5×	1.2k 0.7×	989 0.6×	250 0.6×	138 0.3×	213	4.2k
Karl‐Heinz Altmann Switzerland	46	2.8k 0.8×	1.6k 1.0×	4.0k 2.4×	480 1.2×	275 0.7×	240	8.2k

Countries citing papers authored by Edward E. Knaus

Since Specialization

Citations

This map shows the geographic impact of Edward E. Knaus's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edward E. Knaus with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edward E. Knaus more than expected).

Fields of papers citing papers by Edward E. Knaus

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edward E. Knaus. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edward E. Knaus. The network helps show where Edward E. Knaus may publish in the future.

Co-authorship network of co-authors of Edward E. Knaus

This figure shows the co-authorship network connecting the top 25 collaborators of Edward E. Knaus. A scholar is included among the top collaborators of Edward E. Knaus based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Edward E. Knaus. Edward E. Knaus is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Huang, Zhangjian, Jianbing Wu, Yu Zou, et al.. (2018). Glutathione S-Transferase π-Activatable O²-(Sulfonylethyl Derived) Diazeniumdiolates Potently Suppress Melanoma in Vitro and in Vivo. Journal of Medicinal Chemistry. 61(5). 1833–1844. 17 indexed citations

Biggs, James E., Patrick L. Stemkowski, Edward E. Knaus, et al.. (2014). Suppression of network activity in dorsal horn by gabapentin permeation of TRPV1 channels: Implications for drug access to cytoplasmic targets. Neuroscience Letters. 584. 397–402. 16 indexed citations

Abdellatif, Khaled R.A., Carlos Velázquez, Zhangjian Huang, Morshed Alam Chowdhury, & Edward E. Knaus. (2010). Triaryl (Z)-olefins suitable for radiolabeling with carbon-11 or fluorine-18 radionuclides for positron emission tomography imaging of cyclooxygenase-2 expression in pathological disease. Bioorganic & Medicinal Chemistry Letters. 20(17). 5245–5250. 6 indexed citations

Abdellatif, Khaled R.A., Morshed Alam Chowdhury, Ying Dong, et al.. (2009). Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its aminosulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies. Bioorganic & Medicinal Chemistry. 17(14). 5182–5188. 35 indexed citations

Chowdhury, Morshed Alam, Hua Chen, Khaled R.A. Abdellatif, et al.. (2008). Synthesis and biological evaluation of 1-(benzenesulfonamido)-2-[5-(N-hydroxypyridin-2(1H)-one)]acetylene regioisomers: A novel class of 5-lipoxygenase inhibitors. Bioorganic & Medicinal Chemistry Letters. 18(14). 4195–4198. 12 indexed citations

Rao, Praveen P. N. & Edward E. Knaus. (2008). Evolution of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Cyclooxygenase (COX) Inhibition and Beyond. Journal of Pharmacy & Pharmaceutical Sciences. 11(2). 81–81. 603 indexed citations breakdown →

Rao, Praveen P. N., et al.. (2006). Synthesis and biological evaluation of linear phenylethynylbenzenesulfonamide regioisomers as cyclooxygenase-1/-2 (COX-1/-2) inhibitors. Bioorganic & Medicinal Chemistry. 14(15). 5259–5265. 28 indexed citations

Uddin, Md. Jashim, Praveen P. N. Rao, & Edward E. Knaus. (2004). Design of acyclic triaryl olefins: a new class of potent and selective cyclooxygenase-2 (COX-2) inhibitors. Bioorganic & Medicinal Chemistry Letters. 14(8). 1953–1956. 22 indexed citations

Duan, Weili, Lihua Xu, Aihua Zhou, et al.. (2004). Cytotoxicity and cellular uptake of pyrimidine nucleosides for imaging herpes simplex type-1 thymidine kinase (HSV-1 TK) expression in mammalian cells. Nuclear Medicine and Biology. 31(5). 623–630. 18 indexed citations

10.

Velázquez, Carlos & Edward E. Knaus. (2004). Synthesis and biological evaluation of 1,4-dihydropyridine calcium channel modulators having a diazen-1-ium-1,2-diolate nitric oxide donor moiety for the potential treatment of congestive heart failure. Bioorganic & Medicinal Chemistry. 12(14). 3831–3840. 35 indexed citations

11.

Sun, Wei, et al.. (2003). Dose‐dependent pharmacokinetics of 1‐(2‐Deoxy‐β‐D‐ ribofuranosyl)‐2,4‐difluoro‐5‐iodobenzene: A potential mimic of 5‐iodo‐2′‐deoxyuridine. Biopharmaceutics & Drug Disposition. 24(9). 385–395. 3 indexed citations

12.

Rao, Praveen P. N., Mohsen Amini, Huiying Li, Amgad G. Habeeb, & Edward E. Knaus. (2003). 6-Alkyl, alkoxy, or alkylthio-substituted 3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 13(13). 2205–2209. 35 indexed citations

13.

Knaus, Edward E., et al.. (2000). Reporter gene imaging: Effects of ganciclovir treatment on nucleoside uptake, hypoxia and perfusion in a murine gene therapy tumour model that expresses herpes simplex type-1 thymidine kinase. Nuclear Medicine Communications. 21(2). 129–137. 9 indexed citations

14.

Parang, Keykavous, Edward E. Knaus, & Leonard I. Wiebe. (1998). Synthesis,In VitroAnti-HIV Activity, and Biological Stability of 5′-O-Myristoyl Analogue Derivatives of 3′-Fluoro-2′,3′-Dideoxythymidine (FLT) as Potential Bifunctional Prodrugs of FLT. Nucleosides and Nucleotides. 17(6). 987–1008. 18 indexed citations

15.

Miri, Ramin, Susan E. Howlett, & Edward E. Knaus. (1997). Synthesis and Calcium Channel Modulating Effects of Isopropyl 1,4‐Dihydro‐2,6‐dimethyl‐3‐nitro‐4‐(thienyl)‐5‐pyridinecarboxylates. Archiv der Pharmazie. 330(9-10). 290–294. 19 indexed citations

16.

Iqbal, Nadeem & Edward E. Knaus. (1996). Synthesis and Smooth Muscle Calcium Channel Antagonist Effects of Dialkyl 1,4‐Dihydro‐2,6‐dimethyl‐4‐aryl‐3,5‐pyridinedicarboxylates Containing a Nitrooxy or Nitrophenyl Moiety in the 3‐Alkyl Ester Substituent. Archiv der Pharmazie. 329(1). 23–26. 11 indexed citations

17.

Kumar, Rakesh, Lili Wang, Leonard I. Wiebe, & Edward E. Knaus. (1994). Synthesis, in vitro Biological Stability, and Anti-HIV Activity of 5-Halo-6-alkoxy(or azido)-5,6-dihydro-3'-azido-3'-deoxythymidine Diastereomers as Potential Prodrugs to 3'-Azido-3'-deoxythymidine (AZT). Journal of Medicinal Chemistry. 37(25). 4297–4306. 20 indexed citations

18.

Wolowyk, Michael W., et al.. (1990). Synthesis and activity of 1,4-dihydropyridine analogues of histamine H2-receptor antagonists.. PubMed. 6(2). 101–9. 1 indexed citations

19.

Akula, Murthy R., Wandikayi C. Matowe, Michael W. Wolowyk, & Edward E. Knaus. (1990). Synthesis and Calcium Channel Antagonist Activity of 3-Arylmethyl 5-Isopropyl l,4-Dihydro-2,6-dimethyl-4-(pyridyl)-3,5-pyridinedicarboxylates. Pharmaceutical Research. 7(9). 919–922. 11 indexed citations

20.

Mercer, John R., Li Xu, Edward E. Knaus, & Leonard I. Wiebe. (1989). Synthesis and tumor uptake of 5-bromine-82- and 5-iodine-131-labeled 5-halo-1-(2-fluoro-2-deoxy-.beta.-D-ribofuranosyl)uracils. Journal of Medicinal Chemistry. 32(6). 1289–1294. 23 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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