Edward B. Skibo

1.8k total citations
66 papers, 1.5k citations indexed

About

Edward B. Skibo is a scholar working on Organic Chemistry, Molecular Biology and Toxicology. According to data from OpenAlex, Edward B. Skibo has authored 66 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 50 papers in Organic Chemistry, 39 papers in Molecular Biology and 18 papers in Toxicology. Recurrent topics in Edward B. Skibo's work include Cancer therapeutics and mechanisms (19 papers), Bioactive Compounds and Antitumor Agents (18 papers) and Synthesis and Biological Evaluation (14 papers). Edward B. Skibo is often cited by papers focused on Cancer therapeutics and mechanisms (19 papers), Bioactive Compounds and Antitumor Agents (18 papers) and Synthesis and Biological Evaluation (14 papers). Edward B. Skibo collaborates with scholars based in United States. Edward B. Skibo's co-authors include WILLIAM G. SCHULZ, Imadul Islam, Robert O. Dempcy, Romesh C. Boruah, Robert T. Dorr, Ru Zhou, Daniel V. LaBarbera, Omar M. Khdour, Chengguo Xing and Robert H. Lemus and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Biochemistry.

In The Last Decade

Edward B. Skibo

65 papers receiving 1.4k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Edward B. Skibo United States	23	1.2k	599	358	78	65	66	1.5k
Mohammad Behforouz United States	21	815 0.7×	321 0.5×	184 0.5×	92 1.2×	57 0.9×	36	1.1k
Jean‐Yves Mérour France	26	2.0k 1.7×	775 1.3×	150 0.4×	112 1.4×	146 2.2×	98	2.3k
Raymond Houssin France	22	976 0.8×	782 1.3×	146 0.4×	208 2.7×	72 1.1×	103	1.5k
Masaji Kasai Japan	18	621 0.5×	569 0.9×	263 0.7×	243 3.1×	63 1.0×	64	1.1k
Brigitte Baldeyrou France	23	749 0.6×	710 1.2×	165 0.5×	136 1.7×	46 0.7×	42	1.3k
Jeffrey A. McKie United States	16	868 0.8×	323 0.5×	71 0.2×	75 1.0×	92 1.4×	18	1.0k
William A. Remers United States	22	1.0k 0.9×	774 1.3×	322 0.9×	161 2.1×	56 0.9×	102	1.5k
Jean‐François Peyrat France	28	1.6k 1.4×	559 0.9×	113 0.3×	167 2.1×	148 2.3×	70	2.1k
Wayne K. Anderson United States	20	945 0.8×	433 0.7×	68 0.2×	82 1.1×	97 1.5×	77	1.3k
Subas M. Sakya United States	19	790 0.7×	483 0.8×	69 0.2×	201 2.6×	53 0.8×	37	1.1k

Countries citing papers authored by Edward B. Skibo

Since Specialization

Citations

This map shows the geographic impact of Edward B. Skibo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edward B. Skibo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edward B. Skibo more than expected).

Fields of papers citing papers by Edward B. Skibo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edward B. Skibo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edward B. Skibo. The network helps show where Edward B. Skibo may publish in the future.

Co-authorship network of co-authors of Edward B. Skibo

This figure shows the co-authorship network connecting the top 25 collaborators of Edward B. Skibo. A scholar is included among the top collaborators of Edward B. Skibo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Edward B. Skibo. Edward B. Skibo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Khdour, Omar M. & Edward B. Skibo. (2009). Quinone methide chemistry of prekinamycins: 13C- labeling, spectral global fitting and in vitro studies. Organic & Biomolecular Chemistry. 7(10). 2140–2140. 35 indexed citations

Hargreaves, Robert H. J., Cynthia L. David, Luke Whitesell, et al.. (2008). Discovery of Quinolinediones Exhibiting a Heat Shock Response and Angiogenesis Inhibition. Journal of Medicinal Chemistry. 51(8). 2492–2501. 14 indexed citations

LaBarbera, Daniel V. & Edward B. Skibo. (2004). Synthesis of imidazo[1,5,4-de]quinoxalin-9-ones, benzimidazole analogues of pyrroloiminoquinone marine natural products. Bioorganic & Medicinal Chemistry. 13(2). 387–395. 35 indexed citations

Hargreaves, Robert H. J., Cynthia L. David, Luke Whitesell, & Edward B. Skibo. (2003). Design of quinolinedione-Based geldanamycin analogues. Bioorganic & Medicinal Chemistry Letters. 13(18). 3075–3078. 15 indexed citations

Skibo, Edward B., et al.. (2000). Sigmatropic Reactions of the Aziridinyl Semiquinone Species. Why Aziridinyl Benzoquinones Are Metabolically More Stable than Aziridinyl Indoloquinones. Biochemistry. 39(35). 10770–10780. 23 indexed citations

SCHULZ, WILLIAM G., R.A. Nieman, & Edward B. Skibo. (1995). Evidence for DNA phosphate backbone alkylation and cleavage by pyrrolo[1,2-a]benzimidazoles: small molecules capable of causing base-pair-specific phosphodiester bond hydrolysis.. Proceedings of the National Academy of Sciences. 92(25). 11854–11858. 23 indexed citations

SCHULZ, WILLIAM G., Imadul Islam, & Edward B. Skibo. (1995). Pyrrolo[1,2-a]benzimidazole-Based Quinones and Iminoquinones. The Role of the 3-Substituent on Cytotoxicity. Journal of Medicinal Chemistry. 38(1). 109–118. 46 indexed citations

Skibo, Edward B. & WILLIAM G. SCHULZ. (1995). ChemInform Abstract: Pyrrolo(1,2‐a)benzimidazole‐Based Aziridinyl Quinones, e.g. (I). A New Class of DNA Cleaving Agent Exhibiting G and A Base Specificity.. ChemInform. 26(3). 10 indexed citations

Boruah, Romesh C. & Edward B. Skibo. (1994). A Comparison of the Cytotoxic and Physical Properties of Aziridinyl Quinone Derivatives Based on the Pyrrolo[1,2-a]benzimidazole and Pyrrolo[1,2-a]indole Ring Systems. Journal of Medicinal Chemistry. 37(11). 1625–1631. 39 indexed citations

10.

Skibo, Edward B. & WILLIAM G. SCHULZ. (1993). Pyrrolo[1,2-a]benzimidazole-based aziridinyl quinones. A new class of DNA cleaving agent exhibiting G and A base specificity. Journal of Medicinal Chemistry. 36(21). 3050–3055. 52 indexed citations

11.

Boruah, Romesh C. & Edward B. Skibo. (1993). A mechanistic study of 2-vinylbenzimidazole formation from 2-(2'-haloethyl)benzimidazoles. Synthesis of highly electron-rich vinylic compounds by general base and specific acid-general base catalysis. The Journal of Organic Chemistry. 58(27). 7797–7803. 10 indexed citations

12.

Lemus, Robert H. & Edward B. Skibo. (1992). Design of pyrimido[4,5-g]quinazoline-based anthraquinone mimics. Structure-activity relationship for quinone methide formation and the influence of internal hydrogen bonds on quinone methide fate. The Journal of Organic Chemistry. 57(21). 5649–5660. 12 indexed citations

13.

Islam, Imadul, Edward B. Skibo, Robert T. Dorr, & David S. Alberts. (1991). Structure-activity studies of antitumor agents based on pyrrolo[1,2-a]benzimidazoles: new reductive alkylating DNA cleaving agents. Journal of Medicinal Chemistry. 34(10). 2954–2961. 61 indexed citations

14.

Dempcy, Robert O. & Edward B. Skibo. (1991). Rational design of quinazoline-based irreversible inhibitors of human erythrocyte purine nucleoside phosphorylase. Biochemistry. 30(34). 8480–8487. 75 indexed citations

15.

Islam, Imadul & Edward B. Skibo. (1990). Synthesis and physical studies of azamitosene and iminoazamitosene reductive alkylating agents. Iminoquinone hydrolytic stability, syn/anti isomerization, and electrochemistry. The Journal of Organic Chemistry. 55(10). 3195–3205. 29 indexed citations

16.

Skibo, Edward B., James H. Gilchrist, & Changhee Lee. (1987). Electronic probes of the mechanism of substrate oxidation by buttermilk xanthine oxidase: role of the active-site nucleophile in oxidation. Biochemistry. 26(11). 3032–3037. 21 indexed citations

17.

Skibo, Edward B., et al.. (1987). Active-site-directed reductive alkylation of xanthine oxidase by imidazo[4,5-g]quinazoline-4,9-diones functionalized with a leaving group. Biochemistry. 26(23). 7355–7362. 10 indexed citations

18.

Skibo, Edward B. & Thomas C. Bruice. (1986). High- and low-potential flavin mimics. 3. 3,7,10-Trimethyl-(1H,3H,5H,7H,9H,10H)-pyrimido[5,4-g]pteridine-2,4,6,8-tetrone-mediated reduction of carbon-carbon double bonds .alpha.,.beta. to an acyl function. Journal of the American Chemical Society. 108(7). 1650–1659. 3 indexed citations

19.

Skibo, Edward B. & Thomas C. Bruice. (1983). High- and low-potential flavin mimics (based on the pyrimidino[5,4-g]pteridine and imidazo[4,5-g]pteridine system). 1. General chemistry. Journal of the American Chemical Society. 105(10). 3304–3315. 7 indexed citations

20.

Meyer, Rich B. & Edward B. Skibo. (1979). Synthesis of fused [1,2,6]thiadiazine 1,1-dioxides as potential transition-state analog inhibitors of xanthine oxidase and guanase. Journal of Medicinal Chemistry. 22(8). 944–948. 15 indexed citations

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