Dorothea Scandella

3.8k citations

60 papers · 3.2k indexed · h-index 33

Hematology top 0.2%
- Hemophilia Treatment and Research 55
- Platelet Disorders and Treatments 33
- Blood Coagulation and Thrombosis Mechanisms 24
- Chronic Myeloid Leukemia Treatments 5
Genetics top 1%
- Coagulation, Bradykinin, Polyphosphates, and Angioedema 27
Radiology, Nuclear Medicine and Imaging top 2%
- Monoclonal and Polyclonal Antibodies Research 15
Genetics top 10%
- Coagulation, Bradykinin, Polyphosphates, and Angioedema 27
Molecular Biology
Ecology
- Bacteriophages and microbial interactions 3
Rheumatology
- Eosinophilic Disorders and Syndromes 2

Co-authors: Evgueni L. Saenko Midori Shima Leon W. Hoyer Hiroaki Nakai Pete Lollar John F. Healey Werner Arber Philip J. Fay
Cited by: Hematology Genetics Radiology, Nuclear Medicine and Imaging
Journals: Proceedings of the National Academy of Sciences (1 paper)Journal of Biological Chemistry (11 papers)Journal of Clinical Investigation (2 papers)
Partner nations: United States Japan Germany

In The Last Decade

Dorothea Scandella

59 papers receiving 3.1k citations

Peers

Countries citing papers authored by Dorothea Scandella

Since Specialization

Citations

This map shows the geographic impact of Dorothea Scandella's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dorothea Scandella with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dorothea Scandella more than expected).

Fields of papers citing papers by Dorothea Scandella

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dorothea Scandella. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dorothea Scandella. The network helps show where Dorothea Scandella may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Dorothea Scandella, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Dorothea Scandella Line = papers co-authored together Dorothea Scandella links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	New Characteristics of Anti-Factor VIII Inhibitor Antibody Epitopes and Unusual Immune Responses to Factor VIII Seminars in Thrombosis and Hemostasis ·Dorothea Scandella	2002	14
2	In Hemophilia A and Autoantibody Inhibitor Patients: The Factor VIII A2 Domain and Light Chain Are Most Immunogenic Thrombosis Research ·Dorothea Scandella,Hiroaki Nakai,Matthew Felch,W. Mondorf,I. Scharrer,Leon W. Hoyer,Evgueni L. Saenko	2001	32
3	Detection of all anti-factor VIII antibodies in haemophilia A patients by the Bethesda assay and a more sensitive immunoprecipitation assay Haemophilia ·J. Klinge,G. Auerswald,Ulrich Budde,Holger Klose,W. Kreuz,H. Lenk,Dorothea Scandella,(unknown)	2001	11
4	Properties of Anti-Factor VIII Inhibitor Antibodies in Hemophilia A Patients Seminars in Thrombosis and Hemostasis ·Dorothea Scandella	2000	26
5	Reduction of the antigenicity of factor VIII toward complex inhibitory antibody plasmas using multiply-substituted hybrid human/porcine factor VIII molecules Blood ·Rachel T. Barrow,John F. Healey,David Gailani,Dorothea Scandella,Pete Lollar	2000	88
6	An alloantibody recognizing the FVIII A1 domain in a patient with CRM reduced haemophilia A due to deletion of a large portion of the A1 domain DNA sequence. PubMed ·Masaru Shibata,Midori Shima,Shogo Morichika,John H. McVey,Edward G. D. Tuddenham,Ichiro Tanaka,Hiroshi Suzuki,Keiji Nogami,Yohko Minamoto,Takaaki Hato,Evgueni L. Saenko,Dorothea Scandella,Akira Yoshioka	2000	8
7	Human Inhibitor Antibodies Specific for the Factor VIII A2 Domain Disrupt the Interaction between the Subunit and Factor IXa Journal of Biological Chemistry ·Philip J. Fay,Dorothea Scandella	1999	65
8	Identification of a factor VIII peptide, residues 2315–2330, which neutralizes human factor VIII C2 inhibitor alloantibodies: requirement of Cys²³²⁶ and Glu²³²⁷ for maximum effect British Journal of Haematology ·Keiji Nogami,Midori Shima,Hiroaki Nakai,Ichiro Tanaka,Hiroshi Suzuki,Shogo Morichika,Masaru Shibata,Evgueni L. Saenko,Dorothea Scandella,J. C. Giddings,Akira Yoshioka	1999	24
9	Epitope Specificity and Inactivation Mechanisms of Factor VIII Inhibitor Antibodies Vox Sanguinis ·Dorothea Scandella	1999	1
10	The natural history of the immune response to exogenous factor VIII in severe haemophilia A Haemophilia ·C. A. Lee,Craig M. Kessler,Dana Varon,U. Martinowitz,Markus Heim,Dorothea Scandella,W. Mondorf,J. Klinge	1998	16
11	Transgenic pigs produce functional human factor VIII in milk Nature Biotechnology ·Rekha K. Paleyanda,William H. Velander,Timothy K. Lee,Dorothea Scandella,F.C. Gwazdauskas,J. W. Knight,Leon W. Hoyer,William N. Drohan,Henryk Luboń	1997	94
12	Analysis of the Human Factor VIII A2 Inhibitor Epitope by Alanine Scanning Mutagenesis Journal of Biological Chemistry ·Ira M. Lubin,John F. Healey,Rachel T. Barrow,Dorothea Scandella,Pete Lollar	1997	40
13	Loss of Tolerance to Exogenous and Endogenous Factor VIII in a Mild Hemophilia A Patient With an Arg593 to Cys Mutation Blood ·Arthur R. Thompson,M.E.P. Murphy,Miao‐Liang Liu,Evgueni L. Saenko,John F. Healey,Pete Lollar,Dorothea Scandella	1997	60
14	The Acidic Region of the Factor VIII Light Chain and the C2 Domain Together Form the High Affinity Binding Site for von Willebrand Factor Journal of Biological Chemistry ·Evgueni L. Saenko,Dorothea Scandella	1997	156
15	Slowed Release of Thrombin-cleaved Factor VIII from von Willebrand Factor by a Monoclonal and a Human Antibody Is a Novel Mechanism for Factor VIII Inhibition Journal of Biological Chemistry ·Evgueni L. Saenko,Midori Shima,Gary E. Gilbert,Dorothea Scandella	1996	154
16	A Mechanism for Inhibition of Factor VIII Binding to Phospholipid by von Willebrand Factor Journal of Biological Chemistry ·Evgueni L. Saenko,Dorothea Scandella	1995	81
17	Residues 484-508 Contain a Major Determinant of the Inhibitory Epitope in the A2 Domain of Human Factor VIII Journal of Biological Chemistry ·John F. Healey,Ira M. Lubin,Hiroaki Nakai,Evgueni L. Saenko,Leon W. Hoyer,Dorothea Scandella,Pete Lollar	1995	112
18	Common inhibitory effects of human anti‐C2 domain inhibitor alloantibodies on factor VIII binding to von Willebrand factor British Journal of Haematology ·Midori Shima,Hiroaki Nakai,Dorothea Scandella,Ichiro Tanaka,Y Sawamoto,Seiki Kamisue,Shougo Morichika,Tomohiko Murakami,Akira Yoshioka	1995	58
19	Epitope specificity and functional characterization of factor VIII inhibitors Advances in experimental medicine and biology ·(unknown),Dorothea Scandella,Craig M. Kessler,Pamela C. Esmon,Deborah Hurst,S Courter,Edward D. Gomperts,Matthew Felch,Richard Prescott	1995	20
20	Molecular basis of factor VIII inhibition by human antibodies. Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid. Journal of Clinical Investigation ·Morio Arai,Dorothea Scandella,Leon W. Hoyer	1989	152

About Dorothea Scandella

Dorothea Scandella is a scholar working on Hematology, Genetics and Radiology, Nuclear Medicine and Imaging, having authored 60 papers that have together received 3.2k indexed citations. Recurring topics across this work include Hemophilia Treatment and Research (55 papers), Platelet Disorders and Treatments (33 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (27 papers), Blood Coagulation and Thrombosis Mechanisms (24 papers), Monoclonal and Polyclonal Antibodies Research (15 papers), Chronic Myeloid Leukemia Treatments (5 papers), Bacteriophages and microbial interactions (3 papers) and Eosinophilic Disorders and Syndromes (2 papers). The work is most often cited by research in Hematology (2.8k citations), Genetics (921 citations) and Radiology, Nuclear Medicine and Imaging (626 citations). Dorothea Scandella has collaborated with scholars based in United States, Japan and Germany. Frequent co-authors include Evgueni L. Saenko, Midori Shima, Leon W. Hoyer, Hiroaki Nakai, Pete Lollar, John F. Healey, Werner Arber, Philip J. Fay, Morio Arai and CA Fulcher. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

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