Dorothea Scandella

3.8k citations

60 papers · 3.2k indexed · h-index 33

Hematology top 0.2%
Genetics top 1%
Radiology, Nuclear Medicine and Imaging top 2%
Molecular Biology
Genetics top 10%

Co-authors: Evgueni L. Saenko Midori Shima Leon W. Hoyer Hiroaki Nakai Pete Lollar John F. Healey Werner Arber Philip J. Fay
Topics: Hemophilia Treatment and Research (55 papers)Platelet Disorders and Treatments (33 papers)Coagulation, Bradykinin, Polyphosphates, and Angioedema (27 papers)
Cited by: Hematology Genetics Radiology, Nuclear Medicine and Imaging
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry Journal of Clinical Investigation
Partner nations: United States Japan Germany

In The Last Decade

Dorothea Scandella

59 papers receiving 3.1k citations

Peers

Countries citing papers authored by Dorothea Scandella

Since Specialization

Citations

This map shows the geographic impact of Dorothea Scandella's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dorothea Scandella with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dorothea Scandella more than expected).

Fields of papers citing papers by Dorothea Scandella

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dorothea Scandella. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dorothea Scandella. The network helps show where Dorothea Scandella may publish in the future.

Co-authorship network of co-authors of Dorothea Scandella

This figure shows the co-authorship network connecting the top 25 collaborators of Dorothea Scandella. A scholar is included among the top collaborators of Dorothea Scandella based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dorothea Scandella. Dorothea Scandella is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	New Characteristics of Anti-Factor VIII Inhibitor Antibody Epitopes and Unusual Immune Responses to Factor VIII 2002 ·Seminars in Thrombosis and Hemostasis ·Dorothea Scandella	14
2	In Hemophilia A and Autoantibody Inhibitor Patients: The Factor VIII A2 Domain and Light Chain Are Most Immunogenic 2001 ·Thrombosis Research ·Dorothea Scandella,Hiroaki Nakai,Matthew Felch,(unknown),I. Scharrer,Leon W. Hoyer,Evgueni L. Saenko	32
3	Detection of all anti-factor VIII antibodies in haemophilia A patients by the Bethesda assay and a more sensitive immunoprecipitation assay 2001 ·Haemophilia ·J. Klinge,G. Auerswald,Ulrich Budde,Holger Klose,W. Kreuz,H. Lenk,Dorothea Scandella,(unknown)	11
4	Properties of Anti-Factor VIII Inhibitor Antibodies in Hemophilia A Patients 2000 ·Seminars in Thrombosis and Hemostasis ·Dorothea Scandella	26
5	Reduction of the antigenicity of factor VIII toward complex inhibitory antibody plasmas using multiply-substituted hybrid human/porcine factor VIII molecules 2000 ·Blood ·Rachel T. Barrow,John F. Healey,David Gailani,Dorothea Scandella,Pete Lollar	88
6	An alloantibody recognizing the FVIII A1 domain in a patient with CRM reduced haemophilia A due to deletion of a large portion of the A1 domain DNA sequence. 2000 ·PubMed ·Masaru Shibata,Midori Shima,(unknown),John H. McVey,Edward G. D. Tuddenham,Ichiro Tanaka,Hiroshi Suzuki,Keiji Nogami,(unknown),Takaaki Hato,Evgueni L. Saenko,Dorothea Scandella,Akira Yoshioka	8
7	Human Inhibitor Antibodies Specific for the Factor VIII A2 Domain Disrupt the Interaction between the Subunit and Factor IXa 1999 ·Journal of Biological Chemistry ·Philip J. Fay,Dorothea Scandella	65
8	Identification of a factor VIII peptide, residues 2315–2330, which neutralizes human factor VIII C2 inhibitor alloantibodies: requirement of Cys²³²⁶ and Glu²³²⁷ for maximum effect 1999 ·British Journal of Haematology ·Keiji Nogami,Midori Shima,Hiroaki Nakai,Ichiro Tanaka,Hiroshi Suzuki,(unknown),Masaru Shibata,Evgueni L. Saenko,Dorothea Scandella,J. C. Giddings,Akira Yoshioka	24
9	Epitope Specificity and Inactivation Mechanisms of Factor VIII Inhibitor Antibodies 1999 ·Vox Sanguinis ·Dorothea Scandella	1
10	The natural history of the immune response to exogenous factor VIII in severe haemophilia A 1998 ·Haemophilia ·(unknown),Craig M. Kessler,Dana Varon,U. Martinowitz,Markus Heim,Dorothea Scandella,(unknown),J. Klinge	16
11	Transgenic pigs produce functional human factor VIII in milk 1997 ·Nature Biotechnology ·Rekha K. Paleyanda,William H. Velander,Timothy K. Lee,Dorothea Scandella,F.C. Gwazdauskas,J. W. Knight,Leon W. Hoyer,William N. Drohan,Henryk Luboń	94
12	Analysis of the Human Factor VIII A2 Inhibitor Epitope by Alanine Scanning Mutagenesis 1997 ·Journal of Biological Chemistry ·Ira M. Lubin,John F. Healey,Rachel T. Barrow,Dorothea Scandella,Pete Lollar	40
13	Loss of Tolerance to Exogenous and Endogenous Factor VIII in a Mild Hemophilia A Patient With an Arg593 to Cys Mutation 1997 ·Blood ·Arthur R. Thompson,M.E.P. Murphy,(unknown),Evgueni L. Saenko,John F. Healey,Pete Lollar,Dorothea Scandella	60
14	The Acidic Region of the Factor VIII Light Chain and the C2 Domain Together Form the High Affinity Binding Site for von Willebrand Factor 1997 ·Journal of Biological Chemistry ·Evgueni L. Saenko,Dorothea Scandella	156
15	Slowed Release of Thrombin-cleaved Factor VIII from von Willebrand Factor by a Monoclonal and a Human Antibody Is a Novel Mechanism for Factor VIII Inhibition 1996 ·Journal of Biological Chemistry ·Evgueni L. Saenko,Midori Shima,Gary E. Gilbert,Dorothea Scandella	154
16	A Mechanism for Inhibition of Factor VIII Binding to Phospholipid by von Willebrand Factor 1995 ·Journal of Biological Chemistry ·Evgueni L. Saenko,Dorothea Scandella	81
17	Residues 484-508 Contain a Major Determinant of the Inhibitory Epitope in the A2 Domain of Human Factor VIII 1995 ·Journal of Biological Chemistry ·John F. Healey,Ira M. Lubin,Hiroaki Nakai,Evgueni L. Saenko,Leon W. Hoyer,Dorothea Scandella,Pete Lollar	112
18	Common inhibitory effects of human anti‐C2 domain inhibitor alloantibodies on factor VIII binding to von Willebrand factor 1995 ·British Journal of Haematology ·Midori Shima,Hiroaki Nakai,Dorothea Scandella,Ichiro Tanaka,(unknown),Seiki Kamisue,(unknown),Tomohiko Murakami,Akira Yoshioka	58
19	Epitope specificity and functional characterization of factor VIII inhibitors 1995 ·Advances in experimental medicine and biology ·(unknown),Dorothea Scandella,Craig M. Kessler,(unknown),Deborah Hurst,S Courter,Edward D. Gomperts,Matthew Felch,Richard Prescott	20
20	Molecular basis of factor VIII inhibition by human antibodies. Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid. 1989 ·Journal of Clinical Investigation ·Morio Arai,Dorothea Scandella,Leon W. Hoyer	152

About Dorothea Scandella

Dorothea Scandella is a scholar working on Hematology, Genetics and Radiology, Nuclear Medicine and Imaging, having authored 60 papers that have together received 3.2k indexed citations. Recurring topics across this work include Hemophilia Treatment and Research (55 papers), Platelet Disorders and Treatments (33 papers) and Coagulation, Bradykinin, Polyphosphates, and Angioedema (27 papers). The work is most often cited by research in Hematology (2.8k citations), Genetics (921 citations) and Radiology, Nuclear Medicine and Imaging (626 citations). Dorothea Scandella has collaborated with scholars based in United States, Japan and Germany. Frequent co-authors include Evgueni L. Saenko, Midori Shima, Leon W. Hoyer, Hiroaki Nakai, Pete Lollar, John F. Healey, Werner Arber, Philip J. Fay, Morio Arai and CA Fulcher. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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