Dorian M. Cheff

1.2k total citations · 1 hit paper
13 papers, 490 citations indexed

About

Dorian M. Cheff is a scholar working on Molecular Biology, Pharmacology and Cancer Research. According to data from OpenAlex, Dorian M. Cheff has authored 13 papers receiving a total of 490 indexed citations (citations by other indexed papers that have themselves been cited), including 9 papers in Molecular Biology, 3 papers in Pharmacology and 3 papers in Cancer Research. Recurrent topics in Dorian M. Cheff's work include Redox biology and oxidative stress (4 papers), Glutathione Transferases and Polymorphisms (3 papers) and Cancer, Hypoxia, and Metabolism (2 papers). Dorian M. Cheff is often cited by papers focused on Redox biology and oxidative stress (4 papers), Glutathione Transferases and Polymorphisms (3 papers) and Cancer, Hypoxia, and Metabolism (2 papers). Dorian M. Cheff collaborates with scholars based in United States, Sweden and Hungary. Dorian M. Cheff's co-authors include Matthew D. Hall, Elias S.J. Arnér, Qing Cheng, Karoline Scholzen, Min Shen, Michael Ronzetti, Radosveta Gencheva, Chuying Huang, Anton Simeonov and Bolormaa Baljinnyam and has published in prestigious journals such as Journal of Biological Chemistry, Free Radical Biology and Medicine and Journal of Medicinal Chemistry.

In The Last Decade

Dorian M. Cheff

12 papers receiving 484 citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1

2023 127 citations Dorian M. Cheff, Chuying Huang et al. Redox Biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Dorian M. Cheff United States	10	280	123	114	110	98	13	490
Jennifer L. Allensworth United States	7	281 1.0×	82 0.7×	132 1.2×	44 0.4×	34 0.3×	7	493
Stefan Gradl United States	11	376 1.3×	93 0.8×	47 0.4×	75 0.7×	349 3.6×	19	723
Tong Lan United States	8	243 0.9×	75 0.6×	47 0.4×	69 0.6×	37 0.4×	10	333
Yulia Aleksandrova Russia	12	280 1.0×	80 0.7×	85 0.7×	53 0.5×	79 0.8×	49	502
Laura Caboni Ireland	9	289 1.0×	81 0.7×	74 0.6×	51 0.5×	76 0.8×	11	441
Francis X. Tavares United States	17	345 1.2×	65 0.5×	192 1.7×	100 0.9×	453 4.6×	34	862
Daniela Buac United States	11	446 1.6×	60 0.5×	327 2.9×	32 0.3×	218 2.2×	11	825
Dinesh Chimmanamada United States	6	170 0.6×	57 0.5×	98 0.9×	61 0.6×	82 0.8×	7	383
Luisa Shin Ogawa United States	9	452 1.6×	90 0.7×	164 1.4×	99 0.9×	32 0.3×	17	679

Countries citing papers authored by Dorian M. Cheff

Since Specialization

Citations

This map shows the geographic impact of Dorian M. Cheff's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dorian M. Cheff with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dorian M. Cheff more than expected).

Fields of papers citing papers by Dorian M. Cheff

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dorian M. Cheff. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dorian M. Cheff. The network helps show where Dorian M. Cheff may publish in the future.

Co-authorship network of co-authors of Dorian M. Cheff

This figure shows the co-authorship network connecting the top 25 collaborators of Dorian M. Cheff. A scholar is included among the top collaborators of Dorian M. Cheff based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dorian M. Cheff. Dorian M. Cheff is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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13 of 13 papers shown

Cheff, Dorian M., et al.. (2025). The discovery of a novel ferroptosis-inducing biochemical inhibitor of glutathione peroxidase 4 and thioredoxin reductase 1. Free Radical Biology and Medicine. 233. S62–S63.

Cheff, Dorian M., Hui Guo, Jameson Travers, et al.. (2023). Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX4. Redox Biology. 63. 102719–102719. 20 indexed citations

Cheff, Dorian M., Chuying Huang, Karoline Scholzen, et al.. (2023). The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1. Redox Biology. 62. 102703–102703. 127 indexed citations breakdown →

Scholzen, Karoline, Dorian M. Cheff, Qing Cheng, et al.. (2022). Selective cellular probes for mammalian thioredoxin reductase TrxR1: Rational design of RX1, a modular 1,2-thiaselenane redox probe. Chem. 8(5). 1493–1517. 37 indexed citations

Cheff, Dorian M., Alysson R. Muotri, Brent R. Stockwell, et al.. (2021). Development of therapies for rare genetic disorders of GPX4: roadmap and opportunities. Orphanet Journal of Rare Diseases. 16(1). 446–446. 14 indexed citations

Roth, Jacob S., Tobie D. Lee, Dorian M. Cheff, et al.. (2020). Keeping It Clean: The Cell Culture Quality Control Experience at the National Center for Advancing Translational Sciences. SLAS DISCOVERY. 25(5). 491–497. 6 indexed citations

Sun, Hongmao, et al.. (2020). Predictive models for estimating cytotoxicity on the basis of chemical structures. Bioorganic & Medicinal Chemistry. 28(10). 115422–115422. 25 indexed citations

Lee, Olivia W., Dorian M. Cheff, Tobie D. Lee, et al.. (2019). Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. SLAS DISCOVERY. 25(1). 9–20. 12 indexed citations

Rohde, Jason M., Kyle R. Brimacombe, Li Liu, et al.. (2018). Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors. Bioorganic & Medicinal Chemistry. 26(8). 1727–1739. 35 indexed citations

10.

Yang, Shyh‐Ming, Natalia J. Martinez, Adam Yasgar, et al.. (2018). Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity. Journal of Medicinal Chemistry. 61(11). 4883–4903. 70 indexed citations

11.

Coussens, Nathan P., Stephen C. Kales, Mark J. Henderson, et al.. (2018). High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2. Journal of Biological Chemistry. 293(35). 13750–13765. 55 indexed citations

12.

Cheff, Dorian M., Qing Cheng, Matthew D. Hall, & Elias S.J. Arnér. (2018). Screening for novel inhibitors of glutathione peroxidase. Free Radical Biology and Medicine. 120. S46–S46. 2 indexed citations

13.

Cheff, Dorian M. & Matthew D. Hall. (2017). A Drug of Such Damned Nature.1 Challenges and Opportunities in Translational Platinum Drug Research. Journal of Medicinal Chemistry. 60(11). 4517–4532. 87 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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