Dirk Schnappinger

15.8k total citations · 6 hit papers
115 papers, 11.1k citations indexed

About

Dirk Schnappinger is a scholar working on Molecular Biology, Infectious Diseases and Epidemiology. According to data from OpenAlex, Dirk Schnappinger has authored 115 papers receiving a total of 11.1k indexed citations (citations by other indexed papers that have themselves been cited), including 79 papers in Molecular Biology, 74 papers in Infectious Diseases and 52 papers in Epidemiology. Recurrent topics in Dirk Schnappinger's work include Tuberculosis Research and Epidemiology (73 papers), Mycobacterium research and diagnosis (46 papers) and Biochemical and Molecular Research (29 papers). Dirk Schnappinger is often cited by papers focused on Tuberculosis Research and Epidemiology (73 papers), Mycobacterium research and diagnosis (46 papers) and Biochemical and Molecular Research (29 papers). Dirk Schnappinger collaborates with scholars based in United States, Germany and United Kingdom. Dirk Schnappinger's co-authors include Sabine Ehrt, Gary K. Schoolnik, Martin I. Voskuil, Wolfgang Hillen, Carl Nathan, Kyu Y. Rhee, Maria I. Harrell, David R. Sherman, Gregory Dolganov and Helena I. Boshoff and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Dirk Schnappinger

109 papers receiving 11.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages

2003 1.1k citations Dirk Schnappinger, Sabine Ehrt et al. The Journal of Experimental Medicine profile →
The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

2009 1.0k citations Clifton E. Barry, Helena I. Boshoff et al. profile →
Inhibition of Respiration by Nitric Oxide Induces aMycobacterium tuberculosisDormancy Program

2003 757 citations Martin I. Voskuil, Dirk Schnappinger et al. The Journal of Experimental Medicine profile →
Regulation of theMycobacterium tuberculosishypoxic response gene encoding α-crystallin

2001 613 citations Martin I. Voskuil, Dirk Schnappinger et al. Proceedings of the National Academy of Sciences profile →
Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis

2017 429 citations Michael A. DeJesus, Sae Woong Park et al. profile →
Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

2017 344 citations Jeremy M. Rock, Dirk Schnappinger et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Dirk Schnappinger United States	49	7.0k	5.5k	5.3k	1.5k	1.5k	115	11.1k
Sabine Ehrt United States	56	7.1k 1.0×	5.3k 1.0×	5.5k 1.0×	1.4k 0.9×	1.2k 0.8×	119	11.2k
Christopher M. Sassetti United States	53	7.5k 1.1×	7.0k 1.3×	5.6k 1.1×	1.4k 0.9×	1.7k 1.1×	119	13.2k
Mary Jackson United States	63	5.8k 0.8×	5.1k 0.9×	5.1k 1.0×	1.0k 0.7×	1.0k 0.7×	225	11.0k
Laurent Kremer France	62	7.5k 1.1×	4.9k 0.9×	7.2k 1.4×	1.3k 0.8×	889 0.6×	292	13.1k
David R. Sherman United States	54	8.6k 1.2×	5.0k 0.9×	6.9k 1.3×	1.7k 1.1×	1.3k 0.9×	125	12.5k
Mamadou Daffé France	63	7.6k 1.1×	5.3k 1.0×	7.5k 1.4×	1.3k 0.8×	995 0.7×	191	12.6k
John D. McKinney United States	47	4.7k 0.7×	4.2k 0.8×	3.7k 0.7×	1.2k 0.8×	1.2k 0.8×	118	9.2k
Ying Zhang China	54	6.8k 1.0×	4.5k 0.8×	5.4k 1.0×	1.4k 0.9×	816 0.5×	293	12.1k
Helena I. Boshoff United States	56	6.8k 1.0×	5.7k 1.0×	4.6k 0.9×	1.5k 1.0×	878 0.6×	171	11.2k
Tanya Parish United States	50	5.0k 0.7×	4.0k 0.7×	3.8k 0.7×	939 0.6×	853 0.6×	195	7.8k

Countries citing papers authored by Dirk Schnappinger

Since Specialization

Citations

This map shows the geographic impact of Dirk Schnappinger's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dirk Schnappinger with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dirk Schnappinger more than expected).

Fields of papers citing papers by Dirk Schnappinger

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dirk Schnappinger. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dirk Schnappinger. The network helps show where Dirk Schnappinger may publish in the future.

Co-authorship network of co-authors of Dirk Schnappinger

This figure shows the co-authorship network connecting the top 25 collaborators of Dirk Schnappinger. A scholar is included among the top collaborators of Dirk Schnappinger based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dirk Schnappinger. Dirk Schnappinger is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Zimmerman, Matthew, Curtis A. Engelhart, Patrick K. Quoika, et al.. (2025). Tailored phenyl ureas eradicate drug-resistant Mycobacterium tuberculosis by targeting mycolic acid cell wall assembly. Chemical Science. 16(21). 9472–9483.

Kany, Andreas M., Karin Bartel, Norbert Reiling, et al.. (2025). Design, Synthesis, and Biological Evaluation of Mono- and Diamino-Substituted Squaramide Derivatives as Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthase. Journal of Medicinal Chemistry. 68(23). 25274–25289.

Qu, Di, Peng Ge, Laure Botella, et al.. (2024). Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin. Nature Communications. 15(1). 4161–4161. 3 indexed citations

Bosch, Barbara, Michael A. DeJesus, Dirk Schnappinger, & Jeremy M. Rock. (2024). Weak links: Advancing target‐based drug discovery by identifying the most vulnerable targets. Annals of the New York Academy of Sciences. 1535(1). 10–19. 2 indexed citations

Li, Shuqi, Nicholas C. Poulton, Brian C. VanderVen, et al.. (2023). Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis. eLife. 12. 14 indexed citations

Tiwari, Divya, Claire Healy, Carolina Trujillo, et al.. (2021). Genetic models of latent tuberculosis in mice reveal differential influence of adaptive immunity. The Journal of Experimental Medicine. 218(9). 9 indexed citations

Bockman, Matthew R., Curtis A. Engelhart, Neeraj K. Mishra, et al.. (2019). Investigation of (S)-(−)-Acidomycin: A Selective Antimycobacterial Natural Product That Inhibits Biotin Synthase. ACS Infectious Diseases. 5(4). 598–617. 26 indexed citations

O’Brien, Kathryn, Divya Tiwari, Curtis A. Engelhart, et al.. (2019). Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development. Nature Communications. 10(1). 4970–4970. 86 indexed citations

Bockman, Matthew R., Curtis A. Engelhart, Surendra Dawadi, et al.. (2018). Avoiding Antibiotic Inactivation in Mycobacterium tuberculosis by Rv3406 through Strategic Nucleoside Modification. ACS Infectious Diseases. 4(7). 1102–1113. 14 indexed citations

10.

Dawadi, Surendra, Helena I. Boshoff, Sae Woong Park, Dirk Schnappinger, & Courtney C. Aldrich. (2018). Conformationally Constrained Cinnolinone Nucleoside Analogues as Siderophore Biosynthesis Inhibitors for Tuberculosis. ACS Medicinal Chemistry Letters. 9(4). 386–391. 26 indexed citations

11.

Braud, Emmanuelle, Laura Iannazzo, Dirk Schnappinger, et al.. (2018). Critical Impact of Peptidoglycan Precursor Amidation on the Activity of l,d‐Transpeptidases from Enterococcus faecium and Mycobacterium tuberculosis. Chemistry - A European Journal. 24(22). 5743–5747. 32 indexed citations

12.

Liu, Feng, Surendra Dawadi, Sae Woong Park, et al.. (2017). Structure-Based Optimization of Pyridoxal 5′-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 60(13). 5507–5520. 28 indexed citations

13.

Schnappinger, Dirk. (2015). Genetic Approaches to Facilitate Antibacterial Drug Development. Cold Spring Harbor Perspectives in Medicine. 5(7). a021139–a021139. 12 indexed citations

14.

Kim, Jee-Hyun, Kathryn O’Brien, Ritu Sharma, et al.. (2013). A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence. Proceedings of the National Academy of Sciences. 110(47). 19095–19100. 102 indexed citations

15.

Santangelo, Marı́a de la Paz, Marcelo E. Guerin, M. Coincon, et al.. (2011). Glycolytic and Non-glycolytic Functions of Mycobacterium tuberculosis Fructose-1,6-bisphosphate Aldolase, an Essential Enzyme Produced by Replicating and Non-replicating Bacilli. Journal of Biological Chemistry. 286(46). 40219–40231. 64 indexed citations

16.

Morris, Rowan P., Liem Nguyen, John Gatfield, et al.. (2005). Ancestral antibiotic resistance in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences. 102(34). 12200–12205. 248 indexed citations

17.

Schnappinger, Dirk, Sabine Ehrt, Martin I. Voskuil, et al.. (2003). Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages. The Journal of Experimental Medicine. 198(5). 693–704. 1114 indexed citations breakdown →

18.

Shi, Shuangping, Carl Nathan, Dirk Schnappinger, et al.. (2003). MyD88 Primes Macrophages for Full-Scale Activation by Interferon-γ yet Mediates Few Responses to Mycobacterium tuberculosis. The Journal of Experimental Medicine. 198(7). 987–997. 123 indexed citations

19.

Schnappinger, Dirk. (1998). Determinants of protein-protein recognition by four helix bundles: changing the dimerization specificity of Tet repressor. The EMBO Journal. 17(2). 535–543. 42 indexed citations

20.

Berens, Christian, Dirk Schnappinger, & Wolfgang Hillen. (1997). The Role of the Variable Region in Tet Repressor for Inducibility by Tetracycline. Journal of Biological Chemistry. 272(11). 6936–6942. 22 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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