Diego Acosta‐Alvear

5.0k total citations · 3 hit papers
29 papers, 3.4k citations indexed

About

Diego Acosta‐Alvear is a scholar working on Molecular Biology, Cell Biology and Biotechnology. According to data from OpenAlex, Diego Acosta‐Alvear has authored 29 papers receiving a total of 3.4k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Molecular Biology, 16 papers in Cell Biology and 5 papers in Biotechnology. Recurrent topics in Diego Acosta‐Alvear's work include Endoplasmic Reticulum Stress and Disease (16 papers), RNA regulation and disease (7 papers) and Ubiquitin and proteasome pathways (5 papers). Diego Acosta‐Alvear is often cited by papers focused on Endoplasmic Reticulum Stress and Disease (16 papers), RNA regulation and disease (7 papers) and Ubiquitin and proteasome pathways (5 papers). Diego Acosta‐Alvear collaborates with scholars based in United States, Germany and Canada. Diego Acosta‐Alvear's co-authors include Peter Walter, Brian David Dynlacht, Alexandre Blais, Mary Tsikitis, Yuval Kluger, G Elif Karagöz, Carolina Arias, Avi Ashkenazi, Nathan H. Lents and Yiming Zhou and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Clinical Investigation.

In The Last Decade

Diego Acosta‐Alvear

28 papers receiving 3.3k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

XBP1 Controls Diverse Cell Type- and Condition-Specific Transcriptional Regulatory Networks

2007 665 citations Diego Acosta‐Alvear, Yiming Zhou et al. Molecular Cell profile →
Pharmacological brake-release of mRNA translation enhances cognitive memory

2013 500 citations Diego Acosta‐Alvear, Avi Ashkenazi et al. eLife profile →
Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

2014 447 citations Min Lu, David A. Lawrence et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Diego Acosta‐Alvear United States	20	2.1k	1.8k	922	348	341	29	3.4k
Yanjun Ma United States	16	1.6k 0.8×	2.1k 1.2×	1.1k 1.1×	388 1.1×	485 1.4×	25	3.2k
Thore Hettmann United States	14	2.0k 1.0×	1.7k 0.9×	724 0.8×	488 1.4×	328 1.0×	22	3.5k
Jenna L. Jewell United States	19	2.6k 1.3×	1.9k 1.0×	472 0.5×	338 1.0×	477 1.4×	29	4.3k
Katarzyna Mnich Ireland	17	1.6k 0.8×	1.1k 0.6×	538 0.6×	298 0.9×	157 0.5×	24	2.7k
Hélène Zinszner United States	11	2.1k 1.0×	2.0k 1.1×	921 1.0×	463 1.3×	414 1.2×	11	3.7k
Hai‐Xin Yuan China	22	2.8k 1.3×	2.0k 1.1×	1.8k 2.0×	304 0.9×	256 0.8×	45	5.0k
Diego Rojas‐Rivera Chile	17	1.1k 0.5×	1.1k 0.6×	814 0.9×	315 0.9×	220 0.6×	25	2.0k
Junko Sasaki Japan	25	1.7k 0.8×	647 0.4×	565 0.6×	307 0.9×	272 0.8×	53	2.8k
Katiuscia Bianchi United Kingdom	17	2.7k 1.3×	871 0.5×	1.2k 1.2×	586 1.7×	258 0.8×	27	4.1k
Robert Gourlay United Kingdom	25	2.2k 1.1×	571 0.3×	1.1k 1.2×	265 0.8×	197 0.6×	40	3.3k

Countries citing papers authored by Diego Acosta‐Alvear

Since Specialization

Citations

This map shows the geographic impact of Diego Acosta‐Alvear's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Diego Acosta‐Alvear with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Diego Acosta‐Alvear more than expected).

Fields of papers citing papers by Diego Acosta‐Alvear

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Diego Acosta‐Alvear. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Diego Acosta‐Alvear. The network helps show where Diego Acosta‐Alvear may publish in the future.

Co-authorship network of co-authors of Diego Acosta‐Alvear

This figure shows the co-authorship network connecting the top 25 collaborators of Diego Acosta‐Alvear. A scholar is included among the top collaborators of Diego Acosta‐Alvear based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Diego Acosta‐Alvear. Diego Acosta‐Alvear is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Zappa, Francesca, et al.. (2025). The integrated stress response engages a cell-autonomous, ligand-independent, DR5-driven apoptosis switch. Cell Death and Disease. 16(1). 101–101. 3 indexed citations

Acosta‐Alvear, Diego, Jonathan M. Harnoss, Peter Walter, & Avi Ashkenazi. (2024). Homeostasis control in health and disease by the unfolded protein response. Nature Reviews Molecular Cell Biology. 26(3). 193–212. 29 indexed citations

Solley, Sabrina C., Elena Polishchuk, Julien Bacal, et al.. (2024). Baseline unfolded protein response signaling adjusts the timing of the mammalian cell cycle. Molecular Biology of the Cell. 35(6). br12–br12. 3 indexed citations

Zappa, Francesca, et al.. (2023). Optogenetic control of the integrated stress response reveals proportional encoding and the stress memory landscape. Cell Systems. 14(7). 551–562.e5. 11 indexed citations

Zappa, Francesca, et al.. (2022). Signaling by the integrated stress response kinase PKR is fine-tuned by dynamic clustering. The Journal of Cell Biology. 221(7). 28 indexed citations

Acosta‐Alvear, Diego. (2022). Common signaling principles and interconnectivity in the ISR‐UPR networks. The FASEB Journal. 36(S1).

Rauch, Jennifer N., Morgane Audouard, Eric Valois, et al.. (2022). CREST, a Cas13‐Based, Rugged, Equitable, Scalable Testing (CREST) for SARS‐CoV‐2 Detection in Patient Samples. Current Protocols. 2(2). e385–e385. 3 indexed citations

Solley, Sabrina C., Francesca Zappa, & Diego Acosta‐Alvear. (2020). Regulation of the mammalian cell cycle by the unfolded protein response. The FASEB Journal. 34(S1). 1–1. 1 indexed citations

Karagöz, G Elif, Diego Acosta‐Alvear, & Peter Walter. (2019). The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum. Cold Spring Harbor Perspectives in Biology. 11(9). a033886–a033886. 208 indexed citations

10.

Karagöz, G Elif, Jirka Peschek, Peter Walter, & Diego Acosta‐Alvear. (2019). In vitro RNA Cleavage Assays to Characterize IRE1-dependent RNA Decay. BIO-PROTOCOL. 9(14). e3307–e3307. 1 indexed citations

11.

Acosta‐Alvear, Diego, G Elif Karagöz, Florian Fröhlich, et al.. (2018). The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1. eLife. 7. 71 indexed citations

12.

Karagöz, G Elif, et al.. (2017). An unfolded protein-induced conformational switch activates mammalian IRE1. eLife. 6. 162 indexed citations

13.

Tufanlı, Özlem, Pelin Telkoparan‐Akillilar, Diego Acosta‐Alvear, et al.. (2017). Targeting IRE1 with small molecules counteracts progression of atherosclerosis. Proceedings of the National Academy of Sciences. 114(8). E1395–E1404. 155 indexed citations

14.

Sherbenou, Daniel W., Blake T. Aftab, Su Yang, et al.. (2016). Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells. Journal of Clinical Investigation. 126(12). 4640–4653. 83 indexed citations

15.

Li, Xiaokai, Teresa A. Colvin, Jennifer N. Rauch, et al.. (2015). Validation of the Hsp70–Bag3 Protein–Protein Interaction as a Potential Therapeutic Target in Cancer. Molecular Cancer Therapeutics. 14(3). 642–648. 101 indexed citations

16.

Peschek, Jirka, Diego Acosta‐Alvear, Aaron S. Mendez, & Peter Walter. (2015). A conformational RNA zipper promotes intron ejection during non‐conventional XBP 1 mRNA splicing. EMBO Reports. 16(12). 1688–1698. 35 indexed citations

17.

Lu, Min, David A. Lawrence, Scot A. Marsters, et al.. (2014). Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis. Science. 345(6192). 98–101. 447 indexed citations breakdown →

18.

Asp, Patrik, Diego Acosta‐Alvear, Mary Tsikitis, Chris van Oevelen, & Brian David Dynlacht. (2009). E2f3b plays an essential role in myogenic differentiation through isoform-specific gene regulation. Genes & Development. 23(1). 37–53. 51 indexed citations

19.

Acosta‐Alvear, Diego, Yiming Zhou, Alexandre Blais, et al.. (2007). XBP1 Controls Diverse Cell Type- and Condition-Specific Transcriptional Regulatory Networks. Molecular Cell. 27(1). 53–66. 665 indexed citations breakdown →

20.

Blais, Alexandre, Mary Tsikitis, Diego Acosta‐Alvear, et al.. (2005). An initial blueprint for myogenic differentiation. Genes & Development. 19(5). 553–569. 362 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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