Devin Leake

8.8k citations

48 papers · 6.9k indexed · 4 hit papers · h-index 31

Impact in

Cancer Research top 0.5%
- MicroRNA in disease regulation
Molecular Biology top 1%
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- RNA Research and Splicing
- CRISPR and Genetic Engineering
- RNA and protein synthesis mechanisms
- RNA modifications and cancer

Papers in ⓘ

Molecular Biology 43
- RNA Interference and Gene Delivery 31
- Advanced biosensing and bioanalysis techniques 15
- RNA and protein synthesis mechanisms 8
- RNA Research and Splicing 6
Biomaterials 8
- Silk-based biomaterials and applications 7

Co-authors: Anastasia Khvorova (12 shared papers)Angela Reynolds (10 shared papers)William S. Marshall (8 shared papers)Queta Boese (3 shared papers)Stephen A. Scaringe (2 shared papers)Jon Karpilow (10 shared papers)Yuriy Fedorov (6 shared papers)Emily M. Anderson (6 shared papers)
Journals: Journal of Investigative Dermatology (6 papers)RNA (5 papers)PLoS ONE (4 papers)Nucleic Acids Research (2 papers)Nature Methods (2 papers)
Partner nations: United States United Kingdom Israel

In The Last Decade

Devin Leake

47 papers receiving 6.7k citations

Hit Papers

align trajectories log scale

3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets 2006 · 689 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2006 Nature Methods
2006 RNA
2005 Nature
2004 Nature Biotechnology

Peers

Countries citing papers authored by Devin Leake

Since Specialization

Citations

This map shows the geographic impact of Devin Leake's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Devin Leake with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Devin Leake more than expected).

Fields of papers citing papers by Devin Leake

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Devin Leake. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Devin Leake. The network helps show where Devin Leake may publish in the future.

Co-authors

The 25 scholars most cited alongside Devin Leake, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Devin Leake Line = papers co-authored together Devin Leake links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 48 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Rational siRNA design for RNA interference Nature Biotechnology ·Angela Reynolds, Devin Leake, Queta Boese, Stephen A. Scaringe, William S. Marshall, Anastasia Khvorova Hit paper breakdown →	2004	1601
2	Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability Nature ·Derek C. Radisky, Dan D. Levy, Laurie E. Littlepage, Hong Liu, Celeste M. Nelson, Jimmie E. Fata, Devin Leake, Elizabeth L. Godden, Donna G. Albertson, M. Ángela Nieto, Zena Werb, Mina J. Bissell Hit paper breakdown →	2005	1021
3	3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets Nature Methods ·Amanda Birmingham, Emily M. Anderson, Angela Reynolds, Diane Ilsley-Tyree, Devin Leake, Yuriy Fedorov, Scott Baskerville, Elena Maksimova, Kathryn M. Robinson, Jon Karpilow, William S. Marshall, Anastasia Khvorova Hit paper breakdown →	2006	689
4	Position-specific chemical modification of siRNAs reduces “off-target” transcript silencing RNA ·Aimee L. Jackson, Julja Burchard, Devin Leake, Angela Reynolds, Janell M. Schelter, Jie Guo, Jason M. Johnson, Lee P. Lim, Jon Karpilow, Kim E. Nichols, William S. Marshall, Anastasia Khvorova, Peter S. Linsley Hit paper breakdown →	2006	618
5	Off-target effects by siRNA can induce toxic phenotype RNA ·Yuriy Fedorov, Emily M. Anderson, Amanda Birmingham, Angela Reynolds, Jon Karpilow, Kathryn M. Robinson, Devin Leake, William S. Marshall, Anastasia Khvorova	2006	377
6	Identification of genes that regulate epithelial cell migration using an siRNA screening approach Nature Cell Biology ·Kaylene J. Simpson, Laura M. Selfors, James T. Bui, Angela Reynolds, Devin Leake, Anastasia Khvorova, Joan S. Brugge	2008	327
7	Induction of the interferon response by siRNA is cell type– and duplex length–dependent RNA ·Angela Reynolds, Emily M. Anderson, Annaleen Vermeulen, Yuriy Fedorov, Kathryn M. Robinson, Devin Leake, Jon Karpilow, William S. Marshall, Anastasia Khvorova	2006	251
8	A protocol for designing siRNAs with high functionality and specificity Nature Protocols ·Amanda Birmingham, Emily M. Anderson, Kevin A. Sullivan, Angela Reynolds, Queta Boese, Devin Leake, Jon Karpilow, Anastasia Khvorova	2007	169
9	Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB–siRNA conjugates Nucleic Acids Research ·Trinna Cuellar, Dwight Barnes, Christopher A. Nelson, Joshua Tanguay, Shang‐Fan Yu, Xiaohui Wen, Suzie J. Scales, Julie Gesch, David Davis, Anja van Brabant Smith, Devin Leake, Richard Vandlen, Christian W. Siebel	2014	167
10	Functional Profiling Reveals Critical Role for miRNA in Differentiation of Human Mesenchymal Stem Cells PLoS ONE ·Angela Schoolmeesters, Teresa Eklund, Devin Leake, Annaleen Vermeulen, Queta Smith, Shelley Force Aldred, Yuriy Fedorov	2009	152
11	Experimental validation of the importance of seed complement frequency to siRNA specificity RNA ·Emily M. Anderson, Amanda Birmingham, Scott Baskerville, Angela Reynolds, Elena Maksimova, Devin Leake, Yuriy Fedorov, Jon Karpilow, Anastasia Khvorova	2008	122
12	In Vivo Sustained Release of siRNA from Solid Lipid Nanoparticles ACS Nano ·Tatsiana Lobovkina, Gunilla B. Jacobson, Emilio González-González, Robyn P. Hickerson, Devin Leake, Roger L. Kaspar, Christopher H. Contag, Richard N. Zare	2011	116
13	Stability Study of Unmodified siRNA and Relevance to Clinical Use Oligonucleotides ·Robyn P. Hickerson, Alexander V. Vlassov, Qian Wang, Devin Leake, Heini Ilves, Emilio González-González, Christopher H. Contag, Brian H. Johnston, Roger L. Kaspar	2008	115
14	KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis Journal of Clinical Investigation ·Goutham Narla, Analisa DiFeo, Yolanda Fernández, Saravana M. Dhanasekaran, Fei Huang, Jaya Sangodkar, Eldad A. Hod, Devin Leake, Scott L. Friedman, Simon J. Hall, Arul M. Chinnaiyan, William L. Gerald, Mark A. Rubin, John A. Martignetti	2008	93
15	Single-Nucleotide-Specific siRNA Targeting in a Dominant-Negative Skin Model Journal of Investigative Dermatology ·Robyn P. Hickerson, Frances J.D. Smith, Robert E. Reeves, Christopher H. Contag, Devin Leake, Sancy A. Leachman, Leonard M. Milstone, W.H. Irwin McLean, Roger L. Kaspar	2007	93
16	Double-stranded regions are essential design components of potent inhibitors of RISC function RNA ·A.N. Vermeulen, Barbara Robertson, Andrew B Dalby, William S. Marshall, Jon Karpilow, Devin Leake, Anastasia Khvorova, Scott Baskerville	2007	89
17	Silencing of Reporter Gene Expression in Skin Using siRNAs and Expression of Plasmid DNA Delivered by a Soluble Protrusion Array Device (PAD) Molecular Therapy ·Emilio González-González, Tycho J. Speaker, Robyn P. Hickerson, Ryan Spitler, Manuel A. Flores, Devin Leake, Christopher H. Contag, Roger L. Kaspar	2010	69
18	Specificity and functionality of microRNA inhibitors PubMed ·Barbara Robertson, Andrew B Dalby, Jon Karpilow, Anastasia Khvorova, Devin Leake, Annaleen Vermeulen	2010	62
19	Mechanistic Insights Aid Computational Short Interfering RNA Design Methods in enzymology on CD-ROM/Methods in enzymology ·Queta Boese, Devin Leake, Angela Reynolds, Steven Read, Stephen A. Scaringe, William S. Marshall, Anastasia Khvorova	2005	59
20	Development of Therapeutic siRNAs for Pachyonychia Congenita Journal of Investigative Dermatology ·Frances J.D. Smith, Robyn P. Hickerson, Jane M. Sayers, Robert E. Reeves, Christopher H. Contag, Devin Leake, Roger L. Kaspar, W.H. Irwin McLean	2007	53

About Devin Leake

Devin Leake is a scholar working on Molecular Biology, Biomaterials, Aging, Cell Biology and Cancer Research, having authored 48 papers that have together received 6.9k indexed citations. Recurring topics across this work include RNA Interference and Gene Delivery (31 papers), Advanced biosensing and bioanalysis techniques (15 papers), RNA and protein synthesis mechanisms (8 papers), MicroRNA in disease regulation (7 papers), Silk-based biomaterials and applications (7 papers), Skin and Cellular Biology Research (6 papers), RNA Research and Splicing (6 papers) and Cellular Mechanics and Interactions (4 papers). The work is most often cited by research in Cancer Research (1.9k citations), Molecular Biology (5.6k citations), Cell Biology (584 citations), Genetics (873 citations) and Immunology and Allergy (186 citations). Devin Leake has collaborated with scholars based in United States, United Kingdom and Israel. Frequent co-authors include Anastasia Khvorova, Angela Reynolds, William S. Marshall, Queta Boese, Stephen A. Scaringe, Jon Karpilow, Yuriy Fedorov, Emily M. Anderson, Amanda Birmingham and Kathryn M. Robinson. Their work appears in journals such as Journal of Investigative Dermatology, RNA, PLoS ONE, Nucleic Acids Research and Nature Methods.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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