Derek P. Claxton

1.7k total citations · 1 hit paper
24 papers, 1.1k citations indexed

About

Derek P. Claxton is a scholar working on Molecular Biology, Spectroscopy and Biophysics. According to data from OpenAlex, Derek P. Claxton has authored 24 papers receiving a total of 1.1k indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 6 papers in Spectroscopy and 6 papers in Biophysics. Recurrent topics in Derek P. Claxton's work include Electron Spin Resonance Studies (6 papers), Glycogen Storage Diseases and Myoclonus (4 papers) and Molecular Sensors and Ion Detection (4 papers). Derek P. Claxton is often cited by papers focused on Electron Spin Resonance Studies (6 papers), Glycogen Storage Diseases and Myoclonus (4 papers) and Molecular Sensors and Ion Detection (4 papers). Derek P. Claxton collaborates with scholars based in United States, Japan and India. Derek P. Claxton's co-authors include Hassane S. Mchaourab, Eric Gouaux, Kevin H. Wang, Isabelle Baconguis, April Goehring, Suzanne Fischer, Jennifer Carlisle Michel, Thorsten Althoff, K. Christopher García and Kelli Kazmier and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and PLoS ONE.

In The Last Decade

Derek P. Claxton

24 papers receiving 1.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

2014 503 citations April Goehring, Kevin H. Wang et al. Nature Protocols profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Derek P. Claxton United States	14	806	289	114	102	102	24	1.1k
Wade D. Van Horn United States	24	1.2k 1.5×	221 0.8×	188 1.6×	50 0.5×	68 0.7×	41	1.8k
Elia Zomot Israel	17	548 0.7×	376 1.3×	149 1.3×	79 0.8×	44 0.4×	20	761
Reiko Sakaguchi Japan	23	785 1.0×	155 0.5×	76 0.7×	41 0.4×	57 0.6×	48	1.3k
Valeria Vásquez United States	21	1.2k 1.5×	244 0.8×	93 0.8×	23 0.2×	96 0.9×	42	1.7k
Hsiau‐Wei Lee United States	25	1.2k 1.5×	129 0.4×	183 1.6×	140 1.4×	47 0.5×	64	1.9k
Carole Williams United States	15	1.2k 1.5×	410 1.4×	126 1.1×	60 0.6×	18 0.2×	17	1.5k
Marco G. Casarotto Australia	24	1.3k 1.6×	307 1.1×	67 0.6×	67 0.7×	18 0.2×	87	1.7k
Shangyu Dang China	16	1.1k 1.3×	162 0.6×	62 0.5×	183 1.8×	18 0.2×	26	1.5k
Rǎzvan L. Cornea United States	28	1.7k 2.1×	291 1.0×	76 0.7×	39 0.4×	119 1.2×	73	2.0k
Kun Song China	25	1.3k 1.6×	194 0.7×	89 0.8×	164 1.6×	18 0.2×	70	2.0k

Countries citing papers authored by Derek P. Claxton

Since Specialization

Citations

This map shows the geographic impact of Derek P. Claxton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Derek P. Claxton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Derek P. Claxton more than expected).

Fields of papers citing papers by Derek P. Claxton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Derek P. Claxton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Derek P. Claxton. The network helps show where Derek P. Claxton may publish in the future.

Co-authorship network of co-authors of Derek P. Claxton

This figure shows the co-authorship network connecting the top 25 collaborators of Derek P. Claxton. A scholar is included among the top collaborators of Derek P. Claxton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Derek P. Claxton. Derek P. Claxton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Stein, Richard A., et al.. (2024). Integrative analysis of pathogenic variants in glucose-6-phosphatase based on an AlphaFold2 model. PNAS Nexus. 3(2). pgae036–pgae036. 6 indexed citations

Oeser, James K., Kwang-Ho Kim, Derek P. Claxton, et al.. (2024). Biochemical and metabolic characterization of a G6PC2 inhibitor. Biochimie. 222. 109–122. 2 indexed citations

Claxton, Derek P., et al.. (2023). Identification of structural motifs critical for human G6PC2 function informed by sequence analysis and an AlphaFold2-predicted model. Bioscience Reports. 44(1). 3 indexed citations

Claxton, Derek P., Kevin L. Jagessar, & Hassane S. Mchaourab. (2021). Principles of Alternating Access in Multidrug and Toxin Extrusion (MATE) Transporters. Journal of Molecular Biology. 433(16). 166959–166959. 17 indexed citations

Claxton, Derek P., James K. Oeser, Kritika Singh, et al.. (2021). Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose. Journal of Biological Chemistry. 298(2). 101534–101534. 11 indexed citations

Claxton, Derek P., et al.. (2021). Biophysical and functional properties of purified glucose-6-phosphatase catalytic subunit 1. Journal of Biological Chemistry. 298(1). 101520–101520. 19 indexed citations

Claxton, Derek P., Tsukasa Kusakizako, Wenchang Zhou, et al.. (2021). Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na+ in ion-coupled drug efflux. Journal of Biological Chemistry. 296. 100262–100262. 10 indexed citations

Jagessar, Kevin L., Derek P. Claxton, Richard A. Stein, & Hassane S. Mchaourab. (2020). Sequence and structural determinants of ligand-dependent alternating access of a MATE transporter. Proceedings of the National Academy of Sciences. 117(9). 4732–4740. 27 indexed citations

Han, Bing, Yelena Peskova, Elad Binshtein, et al.. (2020). Structure and assembly of CAV1 8S complexes revealed by single particle electron microscopy. Science Advances. 6(49). 24 indexed citations

10.

Jagessar, Kevin L., Hassane S. Mchaourab, & Derek P. Claxton. (2019). The N-terminal domain of an archaeal multidrug and toxin extrusion (MATE) transporter mediates proton coupling required for prokaryotic drug resistance. Journal of Biological Chemistry. 294(34). 12807–12814. 12 indexed citations

11.

Paz, Aviv, Derek P. Claxton, Kelli Kazmier, et al.. (2018). Conformational transitions of the sodium-dependent sugar transporter, vSGLT. Proceedings of the National Academy of Sciences. 115(12). E2742–E2751. 31 indexed citations

12.

Claxton, Derek P. & Eric Gouaux. (2018). Expression and purification of a functional heteromeric GABAA receptor for structural studies. PLoS ONE. 13(7). e0201210–e0201210. 5 indexed citations

13.

Mishra, Sanjay, Shane A. Chandler, Dewight Williams, et al.. (2018). Engineering of a Polydisperse Small Heat-Shock Protein Reveals Conserved Motifs of Oligomer Plasticity. Structure. 26(8). 1116–1126.e4. 10 indexed citations

14.

Kazmier, Kelli, Derek P. Claxton, & Hassane S. Mchaourab. (2016). Alternating access mechanisms of LeuT-fold transporters: trailblazing towards the promised energy landscapes. Current Opinion in Structural Biology. 45. 100–108. 54 indexed citations

15.

Claxton, Derek P., Kelli Kazmier, Smriti Mishra, & Hassane S. Mchaourab. (2015). Navigating Membrane Protein Structure, Dynamics, and Energy Landscapes Using Spin Labeling and EPR Spectroscopy. Methods in enzymology on CD-ROM/Methods in enzymology. 564. 349–387. 42 indexed citations

16.

Goehring, April, Kevin H. Wang, Jennifer Carlisle Michel, et al.. (2014). Screening and large-scale expression of membrane proteins in mammalian cells for structural studies. Nature Protocols. 9(11). 2574–2585. 503 indexed citations breakdown →

17.

Claxton, Derek P., Matthias Quick, Lei Shi, et al.. (2010). Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters. Nature Structural & Molecular Biology. 17(7). 822–829. 155 indexed citations

18.

Claxton, Derek P., Matthias Quick, Lei Shi, et al.. (2009). Conformational Cycle Of A Bacterial Homolog Of Human Neurotransmitter Sodium Symporters. Biophysical Journal. 96(3). 195a–195a. 1 indexed citations

19.

Kumar, Mukesh, Hanane A. Koteiche, Derek P. Claxton, & Hassane S. Mchaourab. (2008). Disulfide cross‐links in the interaction of a cataract‐linked αA‐crystallin mutant with βB1‐crystallin. FEBS Letters. 583(1). 175–179. 16 indexed citations

20.

Claxton, Derek P., Ping Zou, & Hassane S. Mchaourab. (2007). Structure and Orientation of T4 Lysozyme Bound to the Small Heat Shock Protein α-Crystallin. Journal of Molecular Biology. 375(4). 1026–1039. 21 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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