Dennis A. Dougherty

25.5k total citations · 10 hit papers
256 papers, 21.8k citations indexed

About

Dennis A. Dougherty is a scholar working on Molecular Biology, Organic Chemistry and Spectroscopy. According to data from OpenAlex, Dennis A. Dougherty has authored 256 papers receiving a total of 21.8k indexed citations (citations by other indexed papers that have themselves been cited), including 159 papers in Molecular Biology, 60 papers in Organic Chemistry and 57 papers in Spectroscopy. Recurrent topics in Dennis A. Dougherty's work include Nicotinic Acetylcholine Receptors Study (94 papers), Receptor Mechanisms and Signaling (76 papers) and Ion channel regulation and function (64 papers). Dennis A. Dougherty is often cited by papers focused on Nicotinic Acetylcholine Receptors Study (94 papers), Receptor Mechanisms and Signaling (76 papers) and Ion channel regulation and function (64 papers). Dennis A. Dougherty collaborates with scholars based in United States, United Kingdom and Germany. Dennis A. Dougherty's co-authors include Justin P. Gallivan, Henry A. Lester, David A. Stauffer, Robert A. Kumpf, Anthony P. West, Sandro Mecozzi, Sarah C. R. Lummis, Darren L. Beene, Wenge Zhong and Scott Silverman and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Dennis A. Dougherty

255 papers receiving 21.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Cation−π Interaction

1997 3.1k citations Dennis A. Dougherty et al. Chemical Reviews profile →
Cation-π Interactions in Chemistry and Biology: A New View of Benzene, Phe, Tyr, and Trp

1996 2.4k citations Dennis A. Dougherty Science profile →
Cation-π interactions in structural biology

1999 1.7k citations Justin P. Gallivan, Dennis A. Dougherty Proceedings of the National Academy of Sciences profile →
The Cation−π Interaction

2012 968 citations Dennis A. Dougherty profile →
A Mechanism for Ion Selectivity in Potassium Channels: Computational Studies of Cation-π Interactions

1993 581 citations Dennis A. Dougherty et al. Science profile →
Acetylcholine Binding by a Synthetic Receptor: Implications for Biological Recognition

1990 544 citations Dennis A. Dougherty et al. Science profile →
Cation−π Interactions in Simple Aromatics: Electrostatics Provide a Predictive Tool

1996 451 citations Dennis A. Dougherty et al. Journal of the American Chemical Society profile →
Spin control in organic molecules

1991 427 citations Dennis A. Dougherty profile →
Phenyl–Perfluorophenyl Stacking Interactions: A New Strategy for Supermolecule Construction

1997 410 citations Dennis A. Dougherty, Robert H. Grubbs et al. profile →
The Cation−π Interaction in Chemistry and Biology

2025 23 citations Dennis A. Dougherty Chemical Reviews profile →

Peers

Countries citing papers authored by Dennis A. Dougherty

Since Specialization

Citations

This map shows the geographic impact of Dennis A. Dougherty's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dennis A. Dougherty with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dennis A. Dougherty more than expected).

Fields of papers citing papers by Dennis A. Dougherty

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dennis A. Dougherty. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dennis A. Dougherty. The network helps show where Dennis A. Dougherty may publish in the future.

Co-authorship network of co-authors of Dennis A. Dougherty

This figure shows the co-authorship network connecting the top 25 collaborators of Dennis A. Dougherty. A scholar is included among the top collaborators of Dennis A. Dougherty based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dennis A. Dougherty. Dennis A. Dougherty is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The Cation−π Interaction in Chemistry and Biology breakdown → 2025 ·Chemical Reviews ·Dennis A. Dougherty	23
2	β2 nAChR Activation on VTA DA Neurons Is Sufficient for Nicotine Reinforcement in Rats 2023 ·eNeuro ·(unknown), Yijin Yan, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Henry A. Lester, Dennis A. Dougherty, Katherine M. Holleran, Sara R. Jones, Ryan M. Drenan	7
3	Three Mutations Convert the Selectivity of a Protein Sensor from Nicotinic Agonists to S-Methadone for Use in Cells, Organelles, and Biofluids 2022 ·Journal of the American Chemical Society ·Anand K. Muthusamy, (unknown), Scott C. Virgil, Hailey J. Knox, Jonathan S. Marvin, (unknown), Bruce Cohen, Dennis A. Dougherty, Loren L. Looger, Henry A. Lester	8
4	Characterization of Binding Site Interactions and Selectivity Principles in the α3β4 Nicotinic Acetylcholine Receptor 2022 ·Journal of the American Chemical Society ·Hailey J. Knox, (unknown), Henry A. Lester, Timothy Gallagher, Dennis A. Dougherty	13
5	Probing Binding Interactions of Cytisine Derivatives to the α4β2 Nicotinic Acetylcholine Receptor 2019 ·Journal of the American Chemical Society ·Annet E. M. Blom, (unknown), Henry A. Lester, Timothy Gallagher, Dennis A. Dougherty	24
6	Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors 2019 ·The Journal of General Physiology ·Amol V. Shivange, Philip M. Borden, Anand K. Muthusamy, (unknown), Kallol Bera, Huan Bao, (unknown), (unknown), (unknown), Bruce Cohen, (unknown), (unknown), Dennis A. Dougherty, Edwin R. Chapman, Jonathan S. Marvin, Loren L. Looger, Henry A. Lester	47
7	Menthol Stereoisomers Exhibit Different Effects on α4β2 nAChR Upregulation and Dopamine Neuron Spontaneous Firing 2018 ·eNeuro ·Brandon J. Henderson, (unknown), (unknown), (unknown), (unknown), (unknown), Emad Tajkhorshid, Dennis A. Dougherty, Henry A. Lester	17
8	Imaging Novel Ruthenium bipyridine-based Nanophotoswitches in Retina 2015 ·Investigative Ophthalmology & Visual Science ·Yue Lan, S. Walston, (unknown), (unknown), Dennis A. Dougherty, Robert H. Grubbs, Harry B. Gray, Robert H. Chow, Mark S. Humayun	1
9	Functional Probes of Drug–Receptor Interactions Implicated by Structural Studies: Cys-Loop Receptors Provide a Fertile Testing Ground 2014 ·Journal of Medicinal Chemistry ·Ethan B. Van Arnam, Dennis A. Dougherty	44
10	Investigation of Dopamine Receptor Structure and Function by Structure Prediction and Unnatural Amino Acid Mutagenesis 2012 ·Biophysical Journal ·Ethan B. Van Arnam, (unknown), Fan Liu, Ravinder Abrol, Henry A. Lester, William A. Goddard, Dennis A. Dougherty	1
11	A Gating Charge Transfer Center in Voltage Sensors 2010 ·Science ·Xiao Tao, Alice Lee, Walrati Limapichat, Dennis A. Dougherty, Roderick MacKinnon	385
12	A Cation-π Interaction in the Binding Site of the Glycine Receptor Is Mediated by a Phenylalanine Residue 2008 ·Journal of Neuroscience ·Stephan A. Pless, (unknown), (unknown), Joseph W. Lynch, Henry A. Lester, Sarah C. R. Lummis, Dennis A. Dougherty	66
13	Confirming the Revised C-Terminal Domain of the MscL Crystal Structure 2008 ·Biophysical Journal ·Joshua A. Maurer, Donald E. Elmore, Daniel Clayton, (unknown), Henry A. Lester, Dennis A. Dougherty	7
14	Improved amber and opal suppressor tRNAs for incorporation of unnatural amino acids in vivo. Part 2: Evaluating suppression efficiency 2007 ·RNA ·Erik A. Rodriguez, Henry A. Lester, Dennis A. Dougherty	17
15	5-Fluorotryptamine is a partial agonist at 5-HT3 receptors, and reveals that size and electronegativity at the 5 position of tryptamine are critical for efficient receptor function 2007 ·European Journal of Pharmacology ·(unknown), Kerry L. Price, (unknown), (unknown), Dennis A. Dougherty, Sarah C. R. Lummis	16
16	In vivo incorporation of multiple unnatural amino acids through nonsense and frameshift suppression 2006 ·Proceedings of the National Academy of Sciences ·Erik A. Rodriguez, Henry A. Lester, Dennis A. Dougherty	76
17	Total chemical synthesis and electrophysiological characterization of mechanosensitive channels from Escherichia coli and Mycobacterium tuberculosis 2004 ·Proceedings of the National Academy of Sciences ·Daniel Clayton, George Shapovalov, Joshua A. Maurer, Dennis A. Dougherty, Henry A. Lester, Gerd G. Kochendoerfer	61
18	Tyrosine Residues That Control Binding and Gating in the 5-Hydroxytryptamine₃Receptor Revealed by Unnatural Amino Acid Mutagenesis 2004 ·Journal of Neuroscience ·Darren L. Beene, Kerry L. Price, Henry A. Lester, Dennis A. Dougherty, Sarah C. R. Lummis	81
19	[10] Caging proteins through unnatural amino acids mutagenesis 2003 ·Methods in enzymology on CD-ROM/Methods in enzymology ·E. James Petersson, Gabriel S. Brandt, Niki M. Zacharias, Dennis A. Dougherty, Henry A. Lester	16
20	[28] In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system 1998 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Mark W. Nowak, Justin P. Gallivan, Scott Silverman, Cesar Labarca, Dennis A. Dougherty, Henry A. Lester	148

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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