Dennis A. Dougherty

25.5k total citations · 10 hit papers
256 papers, 21.8k citations indexed

About

Dennis A. Dougherty is a scholar working on Molecular Biology, Organic Chemistry and Spectroscopy. According to data from OpenAlex, Dennis A. Dougherty has authored 256 papers receiving a total of 21.8k indexed citations (citations by other indexed papers that have themselves been cited), including 159 papers in Molecular Biology, 60 papers in Organic Chemistry and 57 papers in Spectroscopy. Recurrent topics in Dennis A. Dougherty's work include Nicotinic Acetylcholine Receptors Study (94 papers), Receptor Mechanisms and Signaling (76 papers) and Ion channel regulation and function (64 papers). Dennis A. Dougherty is often cited by papers focused on Nicotinic Acetylcholine Receptors Study (94 papers), Receptor Mechanisms and Signaling (76 papers) and Ion channel regulation and function (64 papers). Dennis A. Dougherty collaborates with scholars based in United States, United Kingdom and Germany. Dennis A. Dougherty's co-authors include Justin P. Gallivan, Henry A. Lester, David A. Stauffer, Robert A. Kumpf, Anthony P. West, Sandro Mecozzi, Sarah C. R. Lummis, Darren L. Beene, Wenge Zhong and Scott Silverman and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Dennis A. Dougherty

255 papers receiving 21.3k citations

Hit Papers

The Cation−π Interaction 1990 2026 2002 2014 1997 1996 1999 2012 1993 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The Cation−π Interaction
    1997 3.1k citations Dennis A. Dougherty et al. Chemical Reviews profile →
  2. Cation-π Interactions in Chemistry and Biology: A New View of Benzene, Phe, Tyr, and Trp
    1996 2.4k citations Dennis A. Dougherty Science profile →
  3. Cation-π interactions in structural biology
    1999 1.7k citations Justin P. Gallivan, Dennis A. Dougherty Proceedings of the National Academy of Sciences profile →
  4. The Cation−π Interaction
    2012 968 citations Dennis A. Dougherty profile →
  5. A Mechanism for Ion Selectivity in Potassium Channels: Computational Studies of Cation-π Interactions
    1993 581 citations Dennis A. Dougherty et al. Science profile →
  6. Acetylcholine Binding by a Synthetic Receptor: Implications for Biological Recognition
    1990 544 citations Dennis A. Dougherty et al. Science profile →
  7. Cation−π Interactions in Simple Aromatics:  Electrostatics Provide a Predictive Tool
    1996 451 citations Dennis A. Dougherty et al. Journal of the American Chemical Society profile →
  8. Spin control in organic molecules
    1991 427 citations Dennis A. Dougherty profile →
  9. Phenyl–Perfluorophenyl Stacking Interactions: A New Strategy for Supermolecule Construction
    1997 410 citations Dennis A. Dougherty, Robert H. Grubbs et al. profile →
  10. The Cation−π Interaction in Chemistry and Biology
    2025 23 citations Dennis A. Dougherty Chemical Reviews profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Dennis A. Dougherty 10.7k 6.4k 4.4k 4.2k 3.4k 256 21.8k
Stefan Matile 8.3k 0.8× 7.3k 1.1× 3.2k 0.7× 5.1k 1.2× 5.9k 1.8× 392 20.1k
Yoshihisa Inoue 4.4k 0.4× 11.8k 1.8× 2.9k 0.7× 7.3k 1.7× 8.1k 2.4× 528 21.4k
Naomi Sakai 5.7k 0.5× 5.2k 0.8× 2.3k 0.5× 3.2k 0.8× 4.2k 1.2× 286 14.1k
Claudio Toniolo 15.5k 1.4× 8.3k 1.3× 1.0k 0.2× 3.9k 0.9× 2.7k 0.8× 725 20.6k
Steven G. Boxer 14.7k 1.4× 1.9k 0.3× 3.7k 0.8× 2.6k 0.6× 3.6k 1.1× 352 24.1k
Gregorio Weber 13.0k 1.2× 2.7k 0.4× 2.4k 0.5× 3.0k 0.7× 3.2k 0.9× 178 20.0k
Ronald Breslow 10.8k 1.0× 10.4k 1.6× 1.1k 0.3× 2.3k 0.5× 3.7k 1.1× 270 23.5k
George W. Gokel 4.9k 0.5× 8.1k 1.3× 1.9k 0.4× 7.5k 1.8× 3.8k 1.1× 390 16.9k
Jeremy K. M. Sanders 9.2k 0.9× 16.7k 2.6× 3.8k 0.9× 7.7k 1.8× 10.9k 3.2× 424 29.1k
Christopher A. Hunter 6.2k 0.6× 10.9k 1.7× 7.1k 1.6× 5.4k 1.3× 8.7k 2.6× 316 23.6k

Countries citing papers authored by Dennis A. Dougherty

Since Specialization
Citations

This map shows the geographic impact of Dennis A. Dougherty's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dennis A. Dougherty with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dennis A. Dougherty more than expected).

Fields of papers citing papers by Dennis A. Dougherty

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dennis A. Dougherty. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dennis A. Dougherty. The network helps show where Dennis A. Dougherty may publish in the future.

Co-authorship network of co-authors of Dennis A. Dougherty

This figure shows the co-authorship network connecting the top 25 collaborators of Dennis A. Dougherty. A scholar is included among the top collaborators of Dennis A. Dougherty based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dennis A. Dougherty. Dennis A. Dougherty is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Dougherty, Dennis A.. (2025). The Cation−π Interaction in Chemistry and Biology. Chemical Reviews. 125(5). 2793–2808. 23 indexed citations breakdown →
2.
Yan, Yijin, Henry A. Lester, Dennis A. Dougherty, et al.. (2023). β2 nAChR Activation on VTA DA Neurons Is Sufficient for Nicotine Reinforcement in Rats. eNeuro. 10(5). ENEURO.0449–22.2023. 7 indexed citations
3.
Blumenfeld, Zack, Laura Luebbert, Hailey J. Knox, et al.. (2023). Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane. Journal of Neuroscience. 43(13). 2222–2241. 7 indexed citations
4.
Knox, Hailey J., et al.. (2022). Characterization of Binding Site Interactions and Selectivity Principles in the α3β4 Nicotinic Acetylcholine Receptor. Journal of the American Chemical Society. 144(35). 16101–16117. 13 indexed citations
5.
Muthusamy, Anand K., Scott C. Virgil, Hailey J. Knox, et al.. (2022). Three Mutations Convert the Selectivity of a Protein Sensor from Nicotinic Agonists to S-Methadone for Use in Cells, Organelles, and Biofluids. Journal of the American Chemical Society. 144(19). 8480–8486. 8 indexed citations
6.
Blom, Annet E. M., et al.. (2019). Probing Binding Interactions of Cytisine Derivatives to the α4β2 Nicotinic Acetylcholine Receptor. Journal of the American Chemical Society. 141(40). 15840–15849. 24 indexed citations
7.
Shivange, Amol V., Philip M. Borden, Anand K. Muthusamy, et al.. (2019). Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors. The Journal of General Physiology. 151(6). 738–757. 47 indexed citations
8.
Henderson, Brandon J., et al.. (2018). Menthol Stereoisomers Exhibit Different Effects on α4β2 nAChR Upregulation and Dopamine Neuron Spontaneous Firing. eNeuro. 5(6). ENEURO.0465–18.2018. 17 indexed citations
9.
Lan, Yue, S. Walston, Dennis A. Dougherty, et al.. (2015). Imaging Novel Ruthenium bipyridine-based Nanophotoswitches in Retina. Investigative Ophthalmology & Visual Science. 56(7). 1676–1676. 1 indexed citations
10.
Lester, Henry A., et al.. (2015). An Unaltered Orthosteric Site and a Network of Long-Range Allosteric Interactions for PNU-120596 in α7 Nicotinic Acetylcholine Receptors. Chemistry & Biology. 22(8). 1063–1073. 6 indexed citations
11.
Arnam, Ethan B. Van & Dennis A. Dougherty. (2014). Functional Probes of Drug–Receptor Interactions Implicated by Structural Studies: Cys-Loop Receptors Provide a Fertile Testing Ground. Journal of Medicinal Chemistry. 57(15). 6289–6300. 44 indexed citations
12.
Lummis, Sarah C. R., et al.. (2014). Structural Requirements in the Transmembrane Domain of GLIC Revealed by Incorporation of Noncanonical Histidine Analogs. Chemistry & Biology. 21(12). 1700–1706. 21 indexed citations
13.
Miles, Timothy F., Dennis A. Dougherty, & Henry A. Lester. (2013). The 5-HT3AB Receptor Shows an A3B2 Stoichiometry at the Plasma Membrane. Biophysical Journal. 105(4). 887–898. 21 indexed citations
14.
Tao, Xiao, Alice Lee, Walrati Limapichat, Dennis A. Dougherty, & Roderick MacKinnon. (2010). A Gating Charge Transfer Center in Voltage Sensors. Science. 328(5974). 67–73. 385 indexed citations
15.
Puskar, Nyssa L., et al.. (2010). Thinking Outside the Box: Residues that Shape the Agonist Binding Site of Nicotinic Acetylcholine Receptors. Biophysical Journal. 98(3). 132a–132a. 1 indexed citations
16.
Pantoja, Rigo, Erik A. Rodriguez, Mohammed Dibas, Dennis A. Dougherty, & Henry A. Lester. (2009). Single-Molecule Imaging of a Fluorescent Unnatural Amino Acid Incorporated Into Nicotinic Receptors. Biophysical Journal. 96(1). 226–237. 58 indexed citations
17.
Santarelli, Vincent P., Amy L. Eastwood, Dennis A. Dougherty, Christopher A. Ahern, & Richard Horn. (2007). Calcium Block of Single Sodium Channels: Role of a Pore-Lining Aromatic Residue. Biophysical Journal. 93(7). 2341–2349. 34 indexed citations
18.
Rodriguez, Erik A., Henry A. Lester, & Dennis A. Dougherty. (2006). In vivo incorporation of multiple unnatural amino acids through nonsense and frameshift suppression. Proceedings of the National Academy of Sciences. 103(23). 8650–8655. 76 indexed citations
19.
Clayton, Daniel, George Shapovalov, Joshua A. Maurer, et al.. (2004). Total chemical synthesis and electrophysiological characterization of mechanosensitive channels from Escherichia coli and Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences. 101(14). 4764–4769. 61 indexed citations
20.
Nowak, Mark W., Justin P. Gallivan, Scott Silverman, et al.. (1998). [28] In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system. Methods in enzymology on CD-ROM/Methods in enzymology. 293. 504–529. 148 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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