David S. Howell

18.8k citations

154 papers · 6.8k indexed · 2 hit papers · h-index 47

Impact in

Rheumatology top 0.1%
- Osteoarthritis Treatment and Mechanisms
Equine top 0.5%

Papers in

Rheumatology 103
- Osteoarthritis Treatment and Mechanisms 83
- Rheumatoid Arthritis Research and Therapies 11
Orthopedics and Sports Medicine 23
- Tendon Structure and Treatment 15

Co-authors: Julio C. Pita J. Frederick Woessner David D. Dean Jean‐Pierre Pelletier Ofelia E. Muniz Van C. Mow Johanne Martel‐Pelletier Roy D. Altman
Journals: Journal of Clinical Investigation (10 papers)Calcified Tissue International (8 papers)Seminars in Arthritis and Rheumatism (7 papers)Journal of Orthopaedic Research® (6 papers)American Journal of Physiology-Legacy Content (5 papers)
Partner nations: United States Canada Israel

In The Last Decade

David S. Howell

150 papers receiving 6.3k citations

Hit Papers

align trajectories log scale

Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage. 1989 · 519 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1989 Journal of Clinical Investigation
1986 Journal of Orthopaedic Research®

Peers

Countries citing papers authored by David S. Howell

Since Specialization

Citations

This map shows the geographic impact of David S. Howell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David S. Howell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David S. Howell more than expected).

Fields of papers citing papers by David S. Howell

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David S. Howell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David S. Howell. The network helps show where David S. Howell may publish in the future.

Co-authors

The 25 scholars most cited alongside David S. Howell, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David S. Howell Line = papers co-authored together David S. Howell links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Inhibition of insulin‐like growth factor binding protein 5 proteolysis in articular cartilage and joint fluid results in enhanced concentrations of insulin‐like growth factor 1 and is associated with improved osteoarthritis Arthritis & Rheumatism ·David R. Clemmons, Walker H. Busby, H LAHBABI, Duane R. Schultz, David S. Howell, Roy D. Altman, Robert W. Karr	2002	46
2	Articular cartilage calcification and matrix vesicles Current Rheumatology Reports ·David S. Howell	2002	8
3	Altered mechanics and histomorphometry of canine tibial cartilage following joint immobilization Osteoarthritis and Cartilage ·Michelle A. LeRoux, Herman S. Cheung, An Seung Man, A Ruggo, David S. Howell, Lori A. Setton	2001	60
4	Effect of 1α,25-Dihydroxyvitamin D<sub>3</sub> and 24R,25-Dihydroxyvitamin D<sub>3</sub> on Metalloproteinase Activity and Cell Maturation in Growth Plate Cartilage In Vivo Endocrine ·David D. Dean, Barbara D. Boyan, Zvi Schwartz, Ofelia E. Muniz, Manuel Carreño, Shingo Maeda, David S. Howell	2001	30
5	A Cartilage Matrix Deficiency Experimentally Induced by Vitamin B6 Deficiency Experimental Biology and Medicine ·David Duran Rosich, I. Ziv, David E.C. Cole, J. Dennis Mahuren, Sharon M. Donovan, M. Yamauchi, David S. Howell	1998	7
6	Loss of decorin from the surface zone of articular cartilage in a chick model of osteoarthritis Acta Histochemica ·David Duran Rosich, David A. Carrino, P. Minghetti, Leonor Wenger, Rozita Jenabi Oskuie, David S. Howell	1997	4
7	Mechanical behavior and biochemical composition of canine knee cartilage following periods of joint disuse and disuse with remobilization Osteoarthritis and Cartilage ·Lori A. Setton, Van C. Mow, Francisco J. Müller, Julio C. Pita, David S. Howell	1997	73
8	Hepatocyte growth factor and its actions in growth plate chondrocytes Bone ·Robert M. Grumbles, David S. Howell, Leonor Wenger, Roy D. Altman, Guy A. Howard, Bernard A. Roos	1996	30
9	Quantitative Polymerase Chain Reaction Assay for Aggrecan and Link Protein Gene Expression in Cartilage Analytical Biochemistry ·Aye MM Oo, Wilmot B. Valhmu, Trineke Palm, David S. Howell, S G Fischer, Anthony Ratcliffe	1995	31
10	Connective Tissue Integrity is Lost in Vitamin B-6—Deficient Chicks Journal of Nutrition ·Vladislavas Tamėnas, Mitsuo Yamauchi, Rozita Jenabi Oskuie, Stephen P. Coburn, Ofelia E. Muniz, David S. Howell	1995	14
11	Mechanical Properties of Canine Articular Cartilage Are Significantly Altered Following Transection of the Anterior Cruciate Ligament Journal of Orthopaedic Research® ·Lori A. Setton, Van C. Mow, Francisco J. Müller, Julio C. Pita, David S. Howell	1994	195
12	Centrifugal and biochemical comparison of proteoglycan aggregates from articular cartilage in experimental joint disuse and joint instability Journal of Orthopaedic Research® ·Francisco J. Müller, Lori A. Setton, Daniel Manicourt, Van C. Mow, David S. Howell, Julio C. Pita	1994	45
13	Joint cartilage degradation : basic and clinical aspects M. Dekker eBooks ·J. Frederick Woessner, David S. Howell	1993	117
14	Matrix vesicles are enriched in metalloproteinases that degrade proteoglycans Calcified Tissue International ·David D. Dean, Zvi Schwartz, Ofelia E. Muniz, Ruben Gomez, L.D. Swain, David S. Howell, Barbara D. Boyan	1992	84
15	Matrix vesicles contain metalloproteinases that degrade proteoglycans Bone and Mineral ·David D. Dean, Zvi Schwartz, Ofelia E. Muniz, Ruben Gomez, L.D. Swain, David S. Howell, Barbara D. Boyan	1992	20
16	Prophylactic treatment of canine osteoarthritis with glycosaminoglycan polysulfuric acid ester Arthritis & Rheumatism ·Roy D. Altman, David D. Dean, Ofelia E. Muniz, David S. Howell	1989	32
17	Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage. Journal of Clinical Investigation ·David D. Dean, Johanne Martel‐Pelletier, Jean‐Pierre Pelletier, David S. Howell, J. Frederick Woessner Hit paper breakdown →	1989	519
18	Changes in the Sedimentation Profile of Proteoglycan Aggregates in Early Experimental Canine Osteoarthritis Connective Tissue Research ·Daniel Manicourt, Eugene J-M.A. Thonar, Julio C. Pita, David S. Howell	1989	19
19	EHDP‐induced rachitic syndrome in rats is not reversed by vitamin D metabolites The Anatomical Record ·I. Atkin, Asher Ornoy, Julio C. Pita, Ofelia E. Muniz, Kamal Abdel Rahman El- Atrebi, H. V. Ramana Rao, David S. Howell	1988	6
20	Calcificaiton of growth plate cartilage with special reference to studies on micropuncture fluids. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·David S. Howell, Julio C. Pita	1976	47

About David S. Howell

David S. Howell is a scholar working on Rheumatology, Orthopedics and Sports Medicine, Cancer Research, Cell Biology and Nephrology, having authored 154 papers that have together received 6.8k indexed citations. Recurring topics across this work include Osteoarthritis Treatment and Mechanisms (83 papers), Proteoglycans and glycosaminoglycans research (26 papers), Protease and Inhibitor Mechanisms (24 papers), Tendon Structure and Treatment (15 papers), Bone health and treatments (11 papers), Rheumatoid Arthritis Research and Therapies (11 papers), Knee injuries and reconstruction techniques (11 papers) and Cell Adhesion Molecules Research (9 papers). The work is most often cited by research in Rheumatology (4.0k citations), Equine (197 citations), Orthopedics and Sports Medicine (940 citations), Immunology and Allergy (632 citations) and Cancer Research (1.0k citations). David S. Howell has collaborated with scholars based in United States, Canada and Israel. Frequent co-authors include Julio C. Pita, J. Frederick Woessner, David D. Dean, Jean‐Pierre Pelletier, Ofelia E. Muniz, Van C. Mow, Johanne Martel‐Pelletier, Roy D. Altman, Francisco J. Müller and Asher I. Sapolsky. Their work appears in journals such as Journal of Clinical Investigation, Calcified Tissue International, Seminars in Arthritis and Rheumatism, Journal of Orthopaedic Research® and American Journal of Physiology-Legacy Content.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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