David Plouffe

7.9k citations

24 papers · 2.4k indexed · h-index 19

Impact in

Public Health, Environmental and Occupational Health top 1%
- Malaria Research and Control
- Mosquito-borne diseases and control
- Research on Leishmaniasis Studies
Parasitology top 2%

Papers in ⓘ

Public Health, Environmental and Occupational Health 17
- Malaria Research and Control 17
- Mosquito-borne diseases and control 6
Molecular Biology 8
- vaccines and immunoinformatics approaches 2

Co-authors: Elizabeth A. Winzeler (21 shared papers)Yingyao Zhou (8 shared papers)Stephan Meister (5 shared papers)Justin Borevitz (3 shared papers)John R. Yates (2 shared papers)Didier Leroy (2 shared papers)Case W. McNamara (5 shared papers)Guy Oshiro (1 shared paper)
Journals: Bioorganic & Medicinal Chemistry Letters (2 papers)ACS Infectious Diseases (2 papers)PLoS Pathogens (2 papers)Science (2 papers)Genome Research (2 papers)
Partner nations: United States Switzerland Australia

In The Last Decade

David Plouffe

24 papers receiving 2.4k citations

Peers

Countries citing papers authored by David Plouffe

Since Specialization

Citations

This map shows the geographic impact of David Plouffe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Plouffe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Plouffe more than expected).

Fields of papers citing papers by David Plouffe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Plouffe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Plouffe. The network helps show where David Plouffe may publish in the future.

Co-authors

The 25 scholars most cited alongside David Plouffe, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David Plouffe Line = papers co-authored together David Plouffe links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 24 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen Proceedings of the National Academy of Sciences ·David Plouffe, Achim Brinker, Case W. McNamara, Kerstin Henson, Nobutaka Kato, Kelli Kuhen, A. S. Nagle, Francisco Adrián, Jason Matzen, Paul Anderson, Tae‐gyu Nam, Nathanael S. Gray, Arnab K. Chatterjee, Jeff Janes, S. Frank Yan, Richard E. Trager, Jeremy S. Caldwell, Peter G. Schultz, Yingyao Zhou, Elizabeth A. Winzeler	2008	325
2	Large-Scale Identification of Single-Feature Polymorphisms in Complex Genomes Genome Research ·Justin Borevitz, David Liang, David Plouffe, Hur‐Song Chang, Tong Zhu, Detlef Weigel, Charles C. Berry, Elizabeth A. Winzeler, Joanne Chory	2003	300
3	Protein pathway and complex clustering of correlated mRNA and protein expression analyses in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences ·Michael P. Washburn, Antonius Koller, Guy Oshiro, Ryan Ulaszek, David Plouffe, Cosmin Deciu, Elizabeth A. Winzeler, John R. Yates	2003	294
4	The Activities of Current Antimalarial Drugs on the Life Cycle Stages of Plasmodium: A Comparative Study with Human and Rodent Parasites PLoS Medicine ·Michael J. Delves, David Plouffe, Christian Scheurer, Stephan Meister, Sergio Wittlin, Elizabeth A. Winzeler, Robert E. Sinden, Didier Leroy	2012	261
5	Molecular Mechanism for Switching of P. falciparum Invasion Pathways into Human Erythrocytes Science ·Janine Stubbs, Ken Simpson, Tony Triglia, David Plouffe, Christopher J. Tonkin, Manoj T. Duraisingh, Alexander G. Maier, Elizabeth A. Winzeler, Alan F. Cowman	2005	219
6	A Systematic Map of Genetic Variation in Plasmodium falciparum PLoS Pathogens ·Claire Kidgell, Sarah K. Volkman, Johanna P. Daily, Justin Borevitz, David Plouffe, Yingyao Zhou, Jeffrey R. Johnson, Karine G. Le Roch, Ousmane Sarr, Omar Ndir, Soulyemane Mboup, Serge Batalov, Dyann F. Wirth, Elizabeth A. Winzeler	2006	159
7	Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen Families PLoS Genetics ·Selina Bopp, Micah J. Manary, A. Taylor Bright, Geoffrey L. Johnston, Neekesh V. Dharia, Fabio Luna, Susan McCormack, David Plouffe, Case W. McNamara, John R. Walker, David A. Fidock, Eros Lazzerini Denchi, Elizabeth A. Winzeler	2013	144
8	High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission Cell Host & Microbe ·David Plouffe, Melanie Wree, Alan Y. Du, Stephan Meister, Fengwu Li, Kailash P. Patra, (unknown), Shinji L. Okitsu, Erika L. Flannery, Nobutaka Kato, Olga Tanaseichuk, Eamon Comer, Bin Zhou, Kelli Kuhen, Yingyao Zhou, Didier Leroy, Stuart L. Schreiber, Christina Scherer, Joseph M. Vinetz, Elizabeth A. Winzeler	2015	110
9	Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum Genome biology ·Neekesh V. Dharia, Amar Bir Singh Sidhu, María B. Cassera, Scott J Westenberger, Selina Bopp, Rich T Eastman, David Plouffe, Serge Batalov, Daniel J. Park, Sarah K. Volkman, Dyann F. Wirth, Yingyao Zhou, David A. Fidock, Elizabeth A. Winzeler	2009	97
10	Evidence-Based Annotation of the Malaria Parasite's Genome Using Comparative Expression Profiling PLoS ONE ·Yingyao Zhou, Vandana Ramachandran, Kota Arun Kumar, Scott J Westenberger, Phillippe Refour, Bin Zhou, Fengwu Li, Jason A. Young, Kaisheng Chen, David Plouffe, Kerstin Henson, Victor Nussenzweig, Jane M. Carlton, Joseph M. Vinetz, Manoj T. Duraisingh, Elizabeth A. Winzeler	2008	70
11	A Chemical Genomic Analysis of Decoquinate, a Plasmodium falciparum Cytochrome b Inhibitor ACS Chemical Biology ·Tae‐gyu Nam, Case W. McNamara, Selina Bopp, Neekesh V. Dharia, Stephan Meister, Ghislain M. C. Bonamy, David Plouffe, Nobutaka Kato, Susan McCormack, Badry Bursulaya, Hangjun Ke, Akhil B. Vaidya, Peter G. Schultz, Elizabeth A. Winzeler	2011	69
12	Excess Polymorphisms in Genes for Membrane Proteins in Plasmodium falciparum Science ·Sarah K. Volkman, Daniel L. Hartl, Dyann F. Wirth, Kaare Magne Nielsen, Mehee Choi, Serge Batalov, Yingyao Zhou, David Plouffe, Karine G. Le Roch, Ruben Abagyan, Elizabeth A. Winzeler	2002	69
13	A systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparum BMC Genomics ·Karine G. Le Roch, Jeffrey R. Johnson, Hugues Ahiboh, Duk-Won D Chung, Jacques Prudhomme, David Plouffe, Kerstin Henson, Yingyao Zhou, William H. Witola, John R. Yates, Choukri Ben Mamoun, Elizabeth A. Winzeler, Henri Vial	2008	58
14	High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria ACS Infectious Diseases ·Justine Swann, Victoria Corey, Christina Scherer, Nobutaka Kato, Eamon Comer, Micah Maetani, Yevgeniya Antonova‐Koch, Christin Reimer, Kerstin Gagaring, Maureen Ibanez, David Plouffe, Anne‐Marie Zeeman, Clemens H. M. Kocken, Case W. McNamara, Stuart L. Schreiber, Brice Campo, Elizabeth A. Winzeler, Stephan Meister	2016	55
15	Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites Genome Research ·Neekesh V. Dharia, David Plouffe, Selina Bopp, Gonzalo E. González‐Páez, Carmen Lucas, Carola J. Salas, Valeria Soberón, Badry Bursulaya, Tadeusz J. Kochel, David Bacon, Elizabeth A. Winzeler	2010	51
16	Mutations in the Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance mBio ·Gregory LaMonte, Michelle Yi-Xiu Lim, Melanie Wree, Christin Reimer, Marie Nachon, Victoria Corey, Peter Gedeck, David Plouffe, Alan Y. Du, N Varela Figueroa, Bryan K. S. Yeung, Pablo Bifani, Elizabeth A. Winzeler	2016	39
17	Liver‐Targeted Toll‐Like Receptor 7 Agonist Combined With Entecavir Promotes a Functional Cure in the Woodchuck Model of Hepatitis B Virus Hepatology Communications ·Kyle E. Korolowizc, Bin Li, Xu Huang, Changsuek Yon, Evelyn Rodrigo, Manny Corpuz, David Plouffe, Bhaskar Kallakury, Manasa Suresh, Tom Wu, Andrew T. Miller, Stephan Menne	2019	25
18	Probing the Open Global Health Chemical Diversity Library for Multistage-Active Starting Points for Next-Generation Antimalarials ACS Infectious Diseases ·Matthew Abraham, Kerstin Gagaring, Marisa L. Martino, Manu Vanaerschot, David Plouffe, Jaeson Calla, Karla P. Godinez‐Macias, Alan Y. Du, Melanie Wree, Yevgeniya Antonova‐Koch, Korina Eribez, Madeline R. Luth, Sabine Ottilie, David A. Fidock, Case W. McNamara, Elizabeth A. Winzeler	2020	22
19	Discovery of novel 1H-imidazol-2-yl-pyrimidine-4,6-diamines as potential antimalarials Bioorganic & Medicinal Chemistry Letters ·Xianming Deng, A. S. Nagle, Tao Wu, Tomoyo Sakata, Kerstin Henson, Zhong Chen, Kelli Kuhen, David Plouffe, Elizabeth A. Winzeler, Francisco Adrián, Tove Tuntland, Jonathan Chang, Susan Simerson, Steven Howard, Jared Ek, John Isbell, David C. Tully, Arnab K. Chatterjee, Nathanael S. Gray	2010	18
20	Cell-based optimization of novel benzamides as potential antimalarial leads Bioorganic & Medicinal Chemistry Letters ·Tao Wu, A. S. Nagle, Tomoyo Sakata, Kerstin Henson, Rachel Borboa, Zhong Chen, Kelli Kuhen, David Plouffe, Elizabeth A. Winzeler, Francisco Adrián, Tove Tuntland, Jonathan Chang, Susan Simerson, Steven Howard, Jared Ek, John Isbell, Xianming Deng, Nathanael S. Gray, David C. Tully, Arnab K. Chatterjee	2009	11

About David Plouffe

David Plouffe is a scholar working on Public Health, Environmental and Occupational Health, Molecular Biology, Computational Theory and Mathematics, Organic Chemistry and Oncology, having authored 24 papers that have together received 2.4k indexed citations. Recurring topics across this work include Malaria Research and Control (17 papers), Computational Drug Discovery Methods (8 papers), Mosquito-borne diseases and control (6 papers), HIV Research and Treatment (2 papers), Synthesis and biological activity (2 papers), HIV/AIDS drug development and treatment (2 papers), Drug Transport and Resistance Mechanisms (2 papers) and vaccines and immunoinformatics approaches (2 papers). The work is most often cited by research in Public Health, Environmental and Occupational Health (1.5k citations), Parasitology (199 citations), Computational Theory and Mathematics (396 citations), Virology (112 citations) and Immunology (359 citations). David Plouffe has collaborated with scholars based in United States, Switzerland and Australia. Frequent co-authors include Elizabeth A. Winzeler, Yingyao Zhou, Stephan Meister, Justin Borevitz, John R. Yates, Didier Leroy, Case W. McNamara, Guy Oshiro, Antonius Koller and Michael P. Washburn. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, ACS Infectious Diseases, PLoS Pathogens, Science and Genome Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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