David Nicholls

2.2k citations

45 papers · 1.4k indexed · 1 hit paper · h-index 21

Co-authors: Christopher R. Goward Sylvie Pouteau Fiona Tooke Michael D. Scawen N. H. Battey Enrico Coen Haydn G. Beaton Alan C. Tinker
Topics: Enzyme Structure and Function (9 papers)Protein Structure and Dynamics (6 papers)Soil and Water Nutrient Dynamics (5 papers)
Cited by: Biochemistry Molecular Biology Immunology
Journals: Nucleic Acids Research Development Nature Reviews Drug Discovery
Partner nations: United Kingdom United States Sweden

In The Last Decade

David Nicholls

44 papers receiving 1.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Impact of a five-dimensional framework on R&D productivity at AstraZeneca

2018 271 citations Paul Morgan, Dean G. Brown et al. Nature Reviews Drug Discovery profile →

Peers

Countries citing papers authored by David Nicholls

Since Specialization

Citations

This map shows the geographic impact of David Nicholls's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Nicholls with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Nicholls more than expected).

Fields of papers citing papers by David Nicholls

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Nicholls. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Nicholls. The network helps show where David Nicholls may publish in the future.

Co-authorship network of co-authors of David Nicholls

This figure shows the co-authorship network connecting the top 25 collaborators of David Nicholls. A scholar is included among the top collaborators of David Nicholls based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David Nicholls. David Nicholls is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Weekly water quality monitoring data for the River Thames (UK) and its major tributaries (2009–2013): the Thames Initiative research platform 2018 ·Earth system science data ·Michael J. Bowes,Linda Armstrong,Sarah A. Harman,Heather Wickham,David Nicholls,Peter Scarlett,Colin Roberts,Helen P. Jarvie,Gareth Old,E. Gozzard,Nuria Bachiller‐Jareno,Daniel S. Read	37
2	Impact of a five-dimensional framework on R&D productivity at AstraZenecabreakdown → 2018 ·Nature Reviews Drug Discovery ·Paul Morgan,Dean G. Brown,Simon Lennard,Mark J. Anderton,J. Carl Barrett,Ulf G. Eriksson,Mark Fidock,Bengt Hamrén,Anthony Johnson,Ruth March,James Matcham,Jerome T. Mettetal,David Nicholls,Stefan Platz,Steve Rees,Michael Snowden,Menelas N. Pangalos	271
3	Discovery and evaluation of a novel monocyclic series of CXCR2 antagonists 2015 ·Bioorganic & Medicinal Chemistry Letters ·Rupert P. Austin,(unknown),Roger V. Bonnert,(unknown),Anthony R. Cook,Rhona J. Cox,(unknown),A. Gaw,Ken Grime,Premji Meghani,David Nicholls,(unknown),(unknown),John Steele,(unknown)	16
4	Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2 Antagonist 2015 ·Journal of Pharmacology and Experimental Therapeutics ·David Nicholls,Katherine Wiley,Ian Dainty,(unknown),(unknown),A. Gaw,Carina Kärrman Mårdh	67
5	Australia's Naval Shipbuilding Enterprise: Preparing for the 21st Century 2015 ·RAND Corporation eBooks ·(unknown),(unknown),Mark V. Arena,(unknown),Joel B. Predd,(unknown),(unknown),(unknown),(unknown),Gordon Lee,(unknown),Robert Murphy,David Nicholls,(unknown),(unknown),(unknown),Jerry M. Sollinger,(unknown),Obaid Younossi	7
6	Micronucleus induction in the bone marrow of rats by pharmacological mechanisms. II: long-acting beta-2 agonism 2013 ·Mutagenesis ·Ingrid Pontén,P. Jane Mutch,David Nicholls,Alaa Saad,(unknown),Alan Young,Charlotta Fred,Michael R. O’Donovan,Per M. Åberg	2
7	From libraries to candidate: The discovery of new ultra long-acting dibasic β2-adrenoceptor agonists 2011 ·Bioorganic & Medicinal Chemistry Letters ·Lilian Alcaraz,Andrew Bailey,Elaine Cadogan,Stephen Connolly,(unknown),(unknown),Nicholas D. Kindon,(unknown),Mandy Lawson,(unknown),Ian Dainty,David Nicholls,Stuart W. Paine,Garry Pairaudeau,Michael J. Stocks,(unknown),Alan Young	12
8	Agonist‐specific patterns of β₂‐adrenoceptor responses in human airway cells during prolonged exposure 2009 ·British Journal of Pharmacology ·Caroline Düringer,Gunilla Grundström,(unknown),Ian Dainty,Mandy Lawson,Solange H. Korn,(unknown),(unknown),Elisabet Wieslander,Karin Fredriksson,C. Magnus Sköld,Magnus Löfdahl,Claes‐Göran Löfdahl,David Nicholls,David S. Silberstein	20
9	Identification of a Putative Intracellular Allosteric Antagonist Binding-Site in the CXC Chemokine Receptors 1 and 2 2008 ·Molecular Pharmacology ·David Nicholls,(unknown),Katherine Wiley,(unknown),(unknown),Caroline Grahames,A. Gaw,Premji Meghani,Philip A. Shelton,Tracey J. Wright,Philip R. Mallinder	67
10	Floral meristem indeterminacy depends on flower position and is facilitated by acarpellate gynoecium development in Impatiens balsamina 2006 ·New Phytologist ·Tinashe Chiurugwi,Sylvie Pouteau,David Nicholls,Fiona Tooke,Matthew Ordidge,Nick Battey	12
11	2-Aminopyridines as Highly Selective Inducible Nitric Oxide Synthase Inhibitors. Differential Binding Modes Dependent on Nitrogen Substitution 2004 ·Journal of Medicinal Chemistry ·Stephen Connolly,Anders Åberg,A.S. Arvai,Haydn G. Beaton,David R. Cheshire,Anthony R. Cook,(unknown),David Cox,Peter Hamley,(unknown),(unknown),David Nicholls,R.J. Rosenfeld,Stephen A. St-Gallay,John A. Tainer,Alan C. Tinker,A.V. Wallace	37
12	3,4-Dihydro-1-isoquinolinamines: A novel class of nitric oxide synthase inhibitors with a range of isoform selectivity and potency 2001 ·Bioorganic & Medicinal Chemistry Letters ·Haydn G. Beaton,Peter Hamley,David Nicholls,Alan C. Tinker,A.V. Wallace	32
13	Thienopyridines: nitric oxide synthase inhibitors with potent In vivo activity 2001 ·Bioorganic & Medicinal Chemistry Letters ·Haydn G. Beaton,N. K. Boughton-Smith,Peter Hamley,(unknown),David Nicholls,Alan C. Tinker,A.V. Wallace	20
14	Transcription pattern of a FIM homologue in Impatiens during floral development and reversion 1998 ·The Plant Journal ·Sylvie Pouteau,David Nicholls,Fiona Tooke,Enrico Coen,N. H. Battey	14
15	Malate dehydrogenase: A model for structure, evolution, and catalysis 1994 ·Protein Science ·Christopher R. Goward,David Nicholls	195
16	A Single Amino Acid Mutation Enhances the Thermal Stability of Escherichia coli Malate Dehydrogenase 1994 ·European Journal of Biochemistry ·Christopher R. Goward,Julie Ann Miller,David Nicholls,L.I. Irons,Michael D. Scawen,Ronan O’Brien,Babur Z. Chowdhry	21
17	Dissecting the contributions of a specific side‐chain interaction to folding and catalysis of Bacillus stearothermophilus lactate dehydrogenase 1993 ·European Journal of Biochemistry ·David Nicholls,I. Stuart Wood,(unknown),Anthony R. Clarke,J. John Holbrook,Tony Atkinson,Michael D. Scawen	2
18	Overexpression of the Thermus aquaticus B malate dehydrogenase-encoding gene in Escherichia coli 1992 ·Gene ·(unknown),David Nicholls,(unknown),Michael D. Scawen,Tony Atkinson	10
19	The importance of arginine 102 for the substrate specificity of Escherichia coli malate dehydrogenase 1992 ·Biochemical and Biophysical Research Communications ·David Nicholls,Julie Ann Miller,Michael D. Scawen,Anthony R. Clarke,J. John Holbrook,Tony Atkinson,Christopher R. Goward	43
20	Nuleotide sequence of the sucdinyI-CoA synthetase alpha-subunit fromThermus aquaticusB 1988 ·Nucleic Acids Research ·David Nicholls,(unknown),Tony Atkinson,Nigel P. Minton	4

About David Nicholls

David Nicholls is a scholar working on Biochemistry, Environmental Chemistry and Animal Science and Zoology, having authored 45 papers that have together received 1.4k indexed citations. Recurring topics across this work include Enzyme Structure and Function (9 papers), Protein Structure and Dynamics (6 papers) and Soil and Water Nutrient Dynamics (5 papers). The work is most often cited by research in Biochemistry (115 citations), Molecular Biology (594 citations) and Immunology (160 citations). David Nicholls has collaborated with scholars based in United Kingdom, United States and Sweden. Frequent co-authors include Christopher R. Goward, Sylvie Pouteau, Fiona Tooke, Michael D. Scawen, N. H. Battey, Enrico Coen, Haydn G. Beaton, Alan C. Tinker, A.V. Wallace and Peter Hamley. Their work appears in journals such as Nucleic Acids Research, Development and Nature Reviews Drug Discovery.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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