David Nicholls

2.2k total citations · 1 hit paper
45 papers, 1.4k citations indexed

About

David Nicholls is a scholar working on Molecular Biology, Materials Chemistry and Physiology. According to data from OpenAlex, David Nicholls has authored 45 papers receiving a total of 1.4k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 10 papers in Materials Chemistry and 6 papers in Physiology. Recurrent topics in David Nicholls's work include Enzyme Structure and Function (9 papers), Protein Structure and Dynamics (6 papers) and Soil and Water Nutrient Dynamics (5 papers). David Nicholls is often cited by papers focused on Enzyme Structure and Function (9 papers), Protein Structure and Dynamics (6 papers) and Soil and Water Nutrient Dynamics (5 papers). David Nicholls collaborates with scholars based in United Kingdom, United States and Sweden. David Nicholls's co-authors include Christopher R. Goward, Sylvie Pouteau, Michael D. Scawen, Fiona Tooke, N. H. Battey, Enrico Coen, Alan C. Tinker, A.V. Wallace, Haydn G. Beaton and Peter Hamley and has published in prestigious journals such as Nucleic Acids Research, Development and Nature Reviews Drug Discovery.

In The Last Decade

David Nicholls

44 papers receiving 1.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Impact of a five-dimensional framework on R&D productivity at AstraZeneca

2018 271 citations Paul Morgan, Dean G. Brown et al. Nature Reviews Drug Discovery profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David Nicholls United Kingdom	21	594	173	167	160	151	45	1.4k
Luca Cesaro Italy	29	2.1k 3.5×	165 1.0×	434 2.6×	266 1.7×	77 0.5×	92	3.0k
Laura Gribaldo Italy	31	835 1.4×	166 1.0×	229 1.4×	337 2.1×	157 1.0×	107	2.7k
Binghua Jiao China	33	1.9k 3.2×	127 0.7×	233 1.4×	287 1.8×	195 1.3×	155	3.5k
William A. Toscano United States	25	685 1.2×	151 0.9×	97 0.6×	119 0.7×	167 1.1×	51	2.0k
Dirk Bossemeyer Germany	25	1.9k 3.1×	80 0.5×	292 1.7×	88 0.6×	99 0.7×	37	2.4k
David Engelberg Israel	32	2.7k 4.5×	149 0.9×	457 2.7×	207 1.3×	346 2.3×	77	3.8k
Constantinos E. Vorgias Greece	25	1.3k 2.2×	51 0.3×	146 0.9×	98 0.6×	245 1.6×	67	1.7k
Matthieu Garnier France	20	914 1.5×	123 0.7×	224 1.3×	232 1.4×	117 0.8×	31	2.1k
J. HAMELIN France	25	1.4k 2.3×	158 0.9×	252 1.5×	310 1.9×	213 1.4×	65	2.6k
Cinzia Franchin Italy	26	1.1k 1.8×	122 0.7×	125 0.7×	94 0.6×	534 3.5×	70	2.0k

Countries citing papers authored by David Nicholls

Since Specialization

Citations

This map shows the geographic impact of David Nicholls's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Nicholls with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Nicholls more than expected).

Fields of papers citing papers by David Nicholls

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Nicholls. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Nicholls. The network helps show where David Nicholls may publish in the future.

Co-authorship network of co-authors of David Nicholls

This figure shows the co-authorship network connecting the top 25 collaborators of David Nicholls. A scholar is included among the top collaborators of David Nicholls based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David Nicholls. David Nicholls is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bowes, Michael J., Linda Armstrong, Sarah A. Harman, et al.. (2018). Weekly water quality monitoring data for the River Thames (UK) and its major tributaries (2009–2013): the Thames Initiative research platform. Earth system science data. 10(3). 1637–1653. 37 indexed citations

Morgan, Paul, Dean G. Brown, Simon Lennard, et al.. (2018). Impact of a five-dimensional framework on R&D productivity at AstraZeneca. Nature Reviews Drug Discovery. 17(3). 167–181. 271 indexed citations breakdown →

Nicholls, David, et al.. (2015). Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2 Antagonist. Journal of Pharmacology and Experimental Therapeutics. 353(2). 340–350. 67 indexed citations

Austin, Rupert P., Roger V. Bonnert, Anthony R. Cook, et al.. (2015). Discovery and evaluation of a novel monocyclic series of CXCR2 antagonists. Bioorganic & Medicinal Chemistry Letters. 25(7). 1616–1620. 16 indexed citations

Arena, Mark V., Joel B. Predd, Gordon Lee, et al.. (2015). Australia's Naval Shipbuilding Enterprise: Preparing for the 21st Century. RAND Corporation eBooks. 7 indexed citations

Pontén, Ingrid, P. Jane Mutch, David Nicholls, et al.. (2013). Micronucleus induction in the bone marrow of rats by pharmacological mechanisms. II: long-acting beta-2 agonism. Mutagenesis. 28(2). 233–239. 2 indexed citations

Alcaraz, Lilian, Andrew Bailey, Elaine Cadogan, et al.. (2011). From libraries to candidate: The discovery of new ultra long-acting dibasic β2-adrenoceptor agonists. Bioorganic & Medicinal Chemistry Letters. 22(1). 689–695. 12 indexed citations

Düringer, Caroline, Gunilla Grundström, Ian Dainty, et al.. (2009). Agonist‐specific patterns of β₂‐adrenoceptor responses in human airway cells during prolonged exposure. British Journal of Pharmacology. 158(1). 169–179. 20 indexed citations

Nicholls, David, Katherine Wiley, Caroline Grahames, et al.. (2008). Identification of a Putative Intracellular Allosteric Antagonist Binding-Site in the CXC Chemokine Receptors 1 and 2. Molecular Pharmacology. 74(5). 1193–1202. 67 indexed citations

10.

Chiurugwi, Tinashe, Sylvie Pouteau, David Nicholls, et al.. (2006). Floral meristem indeterminacy depends on flower position and is facilitated by acarpellate gynoecium development in Impatiens balsamina. New Phytologist. 173(1). 79–90. 12 indexed citations

11.

Connolly, Stephen, Anders Åberg, A.S. Arvai, et al.. (2004). 2-Aminopyridines as Highly Selective Inducible Nitric Oxide Synthase Inhibitors. Differential Binding Modes Dependent on Nitrogen Substitution. Journal of Medicinal Chemistry. 47(12). 3320–3323. 37 indexed citations

12.

Beaton, Haydn G., Peter Hamley, David Nicholls, Alan C. Tinker, & A.V. Wallace. (2001). 3,4-Dihydro-1-isoquinolinamines: A novel class of nitric oxide synthase inhibitors with a range of isoform selectivity and potency. Bioorganic & Medicinal Chemistry Letters. 11(8). 1023–1026. 32 indexed citations

13.

Pouteau, Sylvie, David Nicholls, Fiona Tooke, Enrico Coen, & N. H. Battey. (1998). Transcription pattern of a FIM homologue in Impatiens during floral development and reversion. The Plant Journal. 14(2). 235–246. 14 indexed citations

14.

Goward, Christopher R., Julie Ann Miller, David Nicholls, et al.. (1994). A Single Amino Acid Mutation Enhances the Thermal Stability of Escherichia coli Malate Dehydrogenase. European Journal of Biochemistry. 224(1). 249–255. 21 indexed citations

15.

Goward, Christopher R. & David Nicholls. (1994). Malate dehydrogenase: A model for structure, evolution, and catalysis. Protein Science. 3(10). 1883–1888. 195 indexed citations

16.

Nicholls, David, I. Stuart Wood, Anthony R. Clarke, et al.. (1993). Dissecting the contributions of a specific side‐chain interaction to folding and catalysis of Bacillus stearothermophilus lactate dehydrogenase. European Journal of Biochemistry. 212(2). 447–455. 2 indexed citations

17.

Nicholls, David, et al.. (1992). Overexpression of the Thermus aquaticus B malate dehydrogenase-encoding gene in Escherichia coli. Gene. 114(1). 139–143. 10 indexed citations

18.

Nicholls, David, Julie Ann Miller, Michael D. Scawen, et al.. (1992). The importance of arginine 102 for the substrate specificity of Escherichia coli malate dehydrogenase. Biochemical and Biophysical Research Communications. 189(2). 1057–1062. 43 indexed citations

19.

Nicholls, David. (1991). The influence of crack blunting on the thermodynamics of fatigue crack growth. Scripta Metallurgica et Materialia. 25(8). 1975–1979. 2 indexed citations

20.

Nicholls, David, et al.. (1988). Nuleotide sequence of the sucdinyI-CoA synthetase alpha-subunit fromThermus aquaticusB. Nucleic Acids Research. 16(20). 9858–9858. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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