Daniel R. O’Brien

25.8k citations

50 papers · 1.5k indexed · h-index 18

Impact in

Cancer Research top 5%
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
Virology top 10%

Papers in

Cancer Research 9
- MicroRNA in disease regulation 3
Clinical Biochemistry 3

Co-authors: Alfonso Eirin André J. van Wijnen Lilach O. Lerman Xiang Zhu Jared M. Evans Scott M. Riester Hui Tang Lewis R. Roberts
Journals: Cancer Research (3 papers)Hepatology (3 papers)Nature Communications (2 papers)Journal of Hepatology (2 papers)BMC Bioinformatics (2 papers)
Partner nations: United States South Korea China

In The Last Decade

Daniel R. O’Brien

49 papers receiving 1.4k citations

Peers

Countries citing papers authored by Daniel R. O’Brien

Since Specialization

Citations

This map shows the geographic impact of Daniel R. O’Brien's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Daniel R. O’Brien with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Daniel R. O’Brien more than expected).

Fields of papers citing papers by Daniel R. O’Brien

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Daniel R. O’Brien. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Daniel R. O’Brien. The network helps show where Daniel R. O’Brien may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Daniel R. O’Brien, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Daniel R. O’Brien Line = papers co-authored together Daniel R. O’Brien links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Utility of Targeted Sequencing Compared to FISH for Detection of Chronic Lymphocytic Leukemia Copy Number Alterations Cancers ·Tianyu Yi, I. Angelozzi, Daniel R. O’Brien, Erik Jessen, Cecília Bonolo de Campos, Nicholas Boddicker, Richard Russel, Cristine Allmer, Kari G. Rabe, James R. Cerhan, Sameer A. Parikh, Neil E. Kay, Huihuang Yan, Daniel L. Van Dyke, Susan L. Slager, Esteban Braggio	2024	2
2	Syngeneic murine models with distinct immune microenvironments represent subsets of human intrahepatic cholangiocarcinoma Journal of Hepatology ·Waqas Ahmed, Binbin Li, Jingchun Yang, Emilien Loeuillard, 謝侑澄, 厚一砂田, Denise De Almeida, Oriana Casasola, 尚勝呂, Daniel R. O’Brien, Rondell P. Graham, Xin Chen, Rory L. Smoot, Haidong Dong, Gregory J. Gores, Sumera I. Ilyas	2024	12
3	Transcriptomic landscapes of effective and failed liver regeneration in humans JHEP Reports ·Patrick Starlinger, И.А. Баранов, I. Angelozzi, David Pereyra, Jonas Santol, Darshan Gambhava, Matthias Hackl, Susanna Skalicky, Hubert Hackl, C Gysel, Daniel R. O’Brien, Renate Kain, Petra Hirsova, Gregory J. Gores, Chen Wang, Thomas Gruenberger, Rory L. Smoot, Alice Assinger	2023	8
4	HILPDA promotes NASH-driven HCC development by restraining intracellular fatty acid flux in hypoxia Journal of Hepatology ·Davide Povero, Yongbin Chen, S. M. Johnson, Girish Gadre, Meixia Pan, Hanmei Bao, Alise Brickhouse, Emily Blake, C Vincent, Daniel R. O’Brien, Yue Yu, Rondell P. Graham, Timuçin Taner, Xianlin Han, Gina L. Razidlo, Jun Liu	2023	24
5	In vivo lentiviral vector gene therapy to cure hereditary tyrosinemia type 1 and prevent development of precancerous and cancerous lesions Nature Communications ·Clara T. Nicolas, Dr.Vipin Kumar Yadav, Raymond Hickey, Zeji Du, L. Kim, Peter Brikitsch, Sheng-Xiang Sun, OO Olubomehin, Mirian Sumica Carneiro Reis, Ahmet Öztürk, Aditya Bhagwate, Daniel R. O’Brien, Jean‐Pierre Kocher, Robert A. Kaiser, Stephen J. Russell, Joseph B. Lillegard	2022	16
6	Exogene: A performant workflow for detecting viral integrations from paired-end next-generation sequencing data PLoS ONE ·Zachary Stephens, Daniel R. O’Brien, Dilay Serttan, Lewis R. Roberts, Ravishankar K. Iyer, Jean‐Pierre Kocher	2021	3
7	Morphological heterogeneity in beta-catenin–mutated hepatocellular carcinomas: implications for tumor molecular classification Human Pathology ·Michael Torbenson, I. Angelozzi, Daniel R. O’Brien, Jun Yin, Oren Collaco, Nguyen H. Tran, Saba Yasir, Jessica Kitchell, Renumathy Dhanasekaran, Keun Soo Ahn, Lewis R. Roberts, Chen Wang	2021	14
8	Duodenal mucosal mitochondrial gene expression is associated with delayed gastric emptying in diabetic gastroenteropathy JCI Insight ·Susrutha Puthanmadhom Narayanan, Daniel R. O’Brien, Mayank Sharma, Karl N. Miller, Peter D. Adams, João F. Passos, Alfonso Eirin, Tamás Ördög, Adil E. Bharucha	2021	10
9	Targeting tumor-associated macrophages and granulocytic myeloid-derived suppressor cells augments PD-1 blockade in cholangiocarcinoma Journal of Clinical Investigation ·Emilien Loeuillard, Jingchun Yang, EeeLN H. Buckarma, Juan Wang, Yuanhang Liu, Caitlin B. Conboy, Kevin D. Pavelko, Ying Li, Daniel R. O’Brien, Chen Wang, Rondell P. Graham, Rory L. Smoot, Haidong Dong, Sumera I. Ilyas	2020	232
10	The YAP-Interacting Phosphatase SHP2 Can Regulate Transcriptional Coactivity and Modulate Sensitivity to Chemotherapy in Cholangiocarcinoma Molecular Cancer Research ·EeeLN H. Buckarma, Nathan W. Werneburg, Caitlin B. Conboy, Ayano Kabashima, Daniel R. O’Brien, Chen Wang, Sumera I. Ilyas, Rory L. Smoot	2020	20
11	Aberrant immunohistochemical expression of CD4 as a rare finding in metastatic melanoma Journal of Cutaneous Pathology ·Kyriakos Chatzopoulos, Daniel R. O’Brien, 寿夫古池, Khashayarsha Khazaie, Jin Jen, Jean‐Pierre Kocher, Svetomir N. Markovic, Thomas J. Flotte	2020	1
12	Genetics of Hepatocellular Carcinoma: Approaches to Explore Molecular Diversity Hepatology ·Stefano Caruso, Daniel R. O’Brien, Sean P. Cleary, Lewis R. Roberts, Jessica Zucman‐Rossi	2020	72
13	BRCA1 Deficiency Upregulates NNMT, Which Reprograms Metabolism and Sensitizes Ovarian Cancer Cells to Mitochondrial Metabolic Targeting Agents Cancer Research ·Arun Kanakkanthara, Kiran Kurmi, Mohamad Fashan Ghazali, Xiaonan Hou, 和達大樹, Ethan P. Heinzen, Cristina Correia, Catherine J. Huntoon, Daniel R. O’Brien, Andrea E. Wahner Hendrickson, Sean C. Dowdy, Hu Li, Ann L. Oberg, Taro Hitosugi, Scott H. Kaufmann, S. John Weroha, Larry M. Karnitz	2019	45
14	An expanded variant list and assembly annotation identifies multiple novel coding and noncoding genes for prostate cancer risk using a normal prostate tissue eQTL data set PLoS ONE ·Melissa S. DeRycke, Melissa C. Larson, Asha Nair, Shannon K. McDonnell, Amy J. French, Lori S. Tillmans, Shaun M. Riska, Saurabh Baheti, Zachary C. Fogarty, Nicholas B. Larson, Daniel R. O’Brien, John C. Cheville, Liang Wang, Daniel J. Schaid, Stephen N. Thibodeau	2019	3
15	ZC3H18 specifically binds and activates the BRCA1 promoter to facilitate homologous recombination in ovarian cancer Nature Communications ·Arun Kanakkanthara, Catherine J. Huntoon, Xiaonan Hou, Minzhi Zhang, Ethan P. Heinzen, Daniel R. O’Brien, Ann L. Oberg, S. John Weroha, Scott H. Kaufmann, Larry M. Karnitz	2019	14
16	Loss of SETD2 Induces a Metabolic Switch in Renal Cell Carcinoma Cell Lines toward Enhanced Oxidative Phosphorylation Journal of Proteome Research ·Jingping Liu, 正子雨宮, Jacqueline Locklear, Teodor Obadă, Erik P. Castle, Douglas F. Lake, Xianfeng Chen, Daniel R. O’Brien, Huijun Luo, Keith D. Robertson, Haiwei Gu, Thai H. Ho	2018	37
17	HGT-ID: an efficient and sensitive workflow to detect human-viral insertion sites using next-generation sequencing data BMC Bioinformatics ·Saurabh Baheti, Xiaojia Tang, Daniel R. O’Brien, Nicholas Chia, Lewis R. Roberts, Heidi Nelson, Judy C. Boughey, Liewei Wang, Matthew P. Goetz, Jean-Pierre A. Kocher, Krishna R. Kalari	2018	14
18	Early genetic aberrations in patients with sporadic colorectal cancer Molecular Carcinogenesis ·心石田, Xiaoyang Ruan, Hugues Sicotte, Daniel R. O’Brien, Hongfang Liu, Jean‐Pierre Kocher, Lisa A. Boardman	2017	21
19	l‐Carnitine Attenuates Cardiac Remodelling rather than Vascular Remodelling in Deoxycorticosterone Acetate‐Salt Hypertensive Rats Basic & Clinical Pharmacology & Toxicology ·Daniel R. O’Brien, Prasad Chunduri, Abishek Iyer, Lindsay Brown	2009	26
20	Eliminating human immunodeficiency virus (HIV) from infected individuals and cells: Is it possible? Medical Hypotheses ·Daniel R. O’Brien	1992	1

About Daniel R. O’Brien

Daniel R. O’Brien is a scholar working on Cancer Research, Clinical Biochemistry, Virology, Oncology and Hepatology, having authored 50 papers that have together received 1.5k indexed citations. Recurring topics across this work include Cholangiocarcinoma and Gallbladder Cancer Studies (7 papers), Genomics and Phylogenetic Studies (5 papers), RNA modifications and cancer (5 papers), Chronic Lymphocytic Leukemia Research (3 papers), MicroRNA in disease regulation (3 papers), Pancreatic and Hepatic Oncology Research (3 papers), Epigenetics and DNA Methylation (3 papers) and Genetic factors in colorectal cancer (3 papers). The work is most often cited by research in Cancer Research (370 citations), Virology (72 citations), Immunology (245 citations), Oncology (301 citations) and Molecular Biology (717 citations). Daniel R. O’Brien has collaborated with scholars based in United States, South Korea and China. Frequent co-authors include Alfonso Eirin, André J. van Wijnen, Lilach O. Lerman, Xiang Zhu, Jared M. Evans, Scott M. Riester, Hui Tang, Lewis R. Roberts, Jean‐Pierre Kocher and Rondell P. Graham. Their work appears in journals such as Cancer Research, Hepatology, Nature Communications, Journal of Hepatology and BMC Bioinformatics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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