Cynthia S. Dowd

1.4k citations

40 papers · 1.1k indexed · h-index 20

Infectious Diseases top 5%
- HIV/AIDS drug development and treatment 7
- Tuberculosis Research and Epidemiology 5
Toxicology top 5%
Pharmacology top 5%
- Microbial Natural Products and Biosynthesis 12
Organic Chemistry top 10%
Virology top 10%
- HIV Research and Treatment 5
Molecular Biology
- Plant biochemistry and biosynthesis 16
- Biochemical and Molecular Research 9
- Cancer therapeutics and mechanisms 5
Public Health, Environmental and Occupational Health
- Malaria Research and Control 5

Co-authors: Helena I. Boshoff Clifton E. BarryXu WangRobin D. Couch Ramandeep Singh Ujjini H. Manjunatha Jan Jiřiček Pilho Kim
Cited by: Infectious Diseases Toxicology Pharmacology
Partner nations: United States Belgium Sweden

In The Last Decade

Cynthia S. Dowd

39 papers receiving 1.1k citations

Peers

Countries citing papers authored by Cynthia S. Dowd

Since Specialization

Citations

This map shows the geographic impact of Cynthia S. Dowd's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Cynthia S. Dowd with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Cynthia S. Dowd more than expected).

Fields of papers citing papers by Cynthia S. Dowd

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Cynthia S. Dowd. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Cynthia S. Dowd. The network helps show where Cynthia S. Dowd may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Cynthia S. Dowd, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Cynthia S. Dowd Line = papers co-authored together Cynthia S. Dowd links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Inhibition of DXR in the MEP pathway with lipophilic N-alkoxyaryl FR900098 analogs Darean A. Bague,Ruiqin Wang,Dana M. Hodge,Marwa O. Mikati,José Santinni Roma,Helena I. Boshoff,Allyson Dailey,Misgina Girma,Robin D. Couch,Audrey R. Odom John,Cynthia S. Dowd	2024	2
2	MEPicides: α,β-unsaturated Fosmidomycin N-Acyl Analogs as Efficient Inhibitors of Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate reductoisomerase Xu Wang,Rachel L. Edwards,Haley Ball,Kenneth M. Heidel,Robert C. Brothers,Claire Johnson,Amanda Haymond,Misgina Girma,Allyson Dailey,José Santinni Roma,Helena I. Boshoff,Damon M. Osbourn,Marvin J. Meyers,Robin D. Couch,Audrey R. Odom John,Cynthia S. Dowd	2023	5
3	Phosphoryl prodrugs: characteristics to improve drug development Samuel A. Kirby,Cynthia S. Dowd	2021	10
4	Structure-guided microbial targeting of antistaphylococcal prodrugs Justin J. Miller,Ishaan T. Shah,Jayda Hatten,Yasaman Barekatain,Elizabeth A. Mueller,Ahmed M. Moustafa,Rachel L. Edwards,Cynthia S. Dowd,Geoffrey C. Hoops,R. Jeremy Johnson,Paul J. Planet,Florian L. Müller,Joseph M. Jez,Audrey R. Odom John	2021	9
5	Potent, specific MEPicides for treatment of zoonotic staphylococci Rachel L. Edwards,Isabel Heueck,Soon Goo Lee,Ishaan T. Shah,Justin J. Miller,Andrew J. Jezewski,Marwa O. Mikati,Xu Wang,Robert C. Brothers,Kenneth M. Heidel,Damon M. Osbourn,Carey‐Ann D. Burnham,Sophie Alvarez,Stephanie A. Fritz,Cynthia S. Dowd,Joseph M. Jez,Audrey R. Odom John	2020	9
6	Vitamin in the Crosshairs: Targeting Pantothenate and Coenzyme A Biosynthesis for New Antituberculosis Agents Hailey S. Butman,Timothy J. Kotzé,Cynthia S. Dowd,Erick Strauss	2020	27
7	MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria Xu Wang,Rachel L. Edwards,Haley Ball,Claire Johnson,Amanda Haymond,Misgina Girma,Michelle Manikkam,Robert C. Brothers,Kyle T. McKay,Stacy D. Arnett,Damon M. Osbourn,Sophie Alvarez,Helena I. Boshoff,Marvin J. Meyers,Robin D. Couch,Audrey R. Odom John,Cynthia S. Dowd	2018	27
8	A high-throughput screening campaign to identify inhibitors of DXP reductoisomerase (IspC) and MEP cytidylyltransferase (IspD) Amanda Haymond,Tyrone Dowdy,Chinchu Johny,Claire Johnson,Haley Ball,Allyson Dailey,Brandon Schweibenz,Karen Villarroel,Richard L. Young,Clark J. Mantooth,Trishal Patel,Jessica Bases,Cynthia S. Dowd,Robin D. Couch	2017	3
9	Some Nigerian anti-tuberculosis ethnomedicines: A preliminary efficacy assessment Nneka N. Ibekwe,J.B. Nvau,Peters Oladosu,Auwal M. Usman,Kolo Ibrahim,Helena I. Boshoff,Cynthia S. Dowd,A. Orisadipe,Olapeju O. Aiyelaagbe,Akinbo A. Adesomoju,Clifton E. Barry,Joseph I. Okogun	2014	25
10	Design of potential bisubstrate inhibitors against Mycobacterium tuberculosis (Mtb) 1-deoxy-d-xylulose 5-phosphate reductoisomerase (Dxr)—evidence of a novel binding mode Géraldine San Jose,Emily R. Jackson,Eugene Uh,Chinchu Johny,Amanda Haymond,Lindsay Lundberg,Chelsea Pinkham,Kylene Kehn‐Hall,Helena I. Boshoff,Robin D. Couch,Cynthia S. Dowd	2013	23
11	Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase (Dxr): A Review of the Synthesis and Biological Evaluation of Recent Inhibitors Emily R. Jackson,Cynthia S. Dowd	2012	59
12	Lipophilic Prodrugs of FR900098 Are Antimicrobial against Francisella novicida In Vivo and In Vitro and Show GlpT Independent Efficacy Elizabeth S. McKenney,Michelle A. Sargent,Hameed Ullah Khan,Eugene Uh,Emily R. Jackson,Géraldine San Jose,Robin D. Couch,Cynthia S. Dowd,Monique L. van Hoek	2012	40
13	Gurumurthy, M. et al. Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles. FEBS J. 279, 113-125 Meera Gurumurthy,Tathagata Mukherjee,Cynthia S. Dowd,Ramandeep Singh,Pornwaratt Niyomrattanakit,Jo Ann Tay,Amit Nayyar,Yong Sok Lee,Joseph Cherian,Helena I. Boshoff,Thomas Dick,Clifton E. Barry,Ujjini H. Manjunatha	2012	1
14	Substrate specificity of the deazaflavin‐dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles Meera Gurumurthy,Tathagata Mukherjee,Cynthia S. Dowd,Ramandeep Singh,Pornwaratt Niyomrattanakit,Jo Ann Tay,Amit Nayyar,Yong Sok Lee,Joseph Cherian,Helena I. Boshoff,Thomas Dick,Clifton E. Barry,Ujjini H. Manjunatha	2011	71
15	Antibacterial and antitubercular activity of fosmidomycin, FR900098, and their lipophilic analogs Eugene Uh,Emily R. Jackson,Géraldine San Jose,Marcus M. Maddox,Robin E. Lee,Richard Lee,Helena I. Boshoff,Cynthia S. Dowd	2011	60
16	The effect of 5-substitution on the electrochemical behavior and antitubercular activity of PA-824 Soledad Bollo,Luis J. Núñez‐Vergara,Sun‐Hee Kang,Liang Zhang,Helena I. Boshoff,Clifton E. Barry,J.A. Squella,Cynthia S. Dowd	2010	17
17	9-aminoacridine Inhibition of HIV-1 Tat Dependent Transcription Irene Guendel,Lawrence Carpio,Rebecca Easley,Rachel Van Duyne,William Coley,Emmanuel Agbottah,Cynthia S. Dowd,Fatah Kashanchi,Kylene Kehn‐Hall	2009	23
18	Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation Weilin Wu,Kylene Kehn‐Hall,Caitlin Pedati,Lynnsey Zweier,Iris Castro,Zachary Klase,Cynthia S. Dowd,Larisa Dubrovsky,Michael Bukrinsky,Fatah Kashanchi	2008	18
19	Prospects for Clinical Introduction of Nitroimidazole Antibiotics for the Treatment of Tuberculosis Clifton E. Barry,Helena I. Boshoff,Cynthia S. Dowd	2004	116
20	From receptor recognition mechanisms to bioinspired mimetic antagonists in HIV-1/cell docking Cynthia S. Dowd,Wentao Zhang,Chuanzhao Li,Irwin Chaiken	2001	4

About Cynthia S. Dowd

Cynthia S. Dowd is a scholar working on Virology, Toxicology and Pharmacology, having authored 40 papers that have together received 1.1k indexed citations. Recurring topics across this work include Plant biochemistry and biosynthesis (16 papers), Microbial Natural Products and Biosynthesis (12 papers), Biochemical and Molecular Research (9 papers), HIV/AIDS drug development and treatment (7 papers), HIV Research and Treatment (5 papers), Tuberculosis Research and Epidemiology (5 papers), Cancer therapeutics and mechanisms (5 papers) and Malaria Research and Control (5 papers). The work is most often cited by research in Infectious Diseases (349 citations), Toxicology (47 citations) and Pharmacology (179 citations). Cynthia S. Dowd has collaborated with scholars based in United States, Belgium and Sweden. Frequent co-authors include Helena I. Boshoff, Clifton E. Barry, Xu Wang, Robin D. Couch, Ramandeep Singh, Ujjini H. Manjunatha, Jan Jiřiček, Pilho Kim, Thomas H. Keller and Amanda Haymond.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact