Clark C. Chen

9.8k total citations · 2 hit papers
120 papers, 5.5k citations indexed

About

Clark C. Chen is a scholar working on Genetics, Molecular Biology and Epidemiology. According to data from OpenAlex, Clark C. Chen has authored 120 papers receiving a total of 5.5k indexed citations (citations by other indexed papers that have themselves been cited), including 61 papers in Genetics, 33 papers in Molecular Biology and 31 papers in Epidemiology. Recurrent topics in Clark C. Chen's work include Glioma Diagnosis and Treatment (61 papers), Meningioma and schwannoma management (28 papers) and Brain Metastases and Treatment (27 papers). Clark C. Chen is often cited by papers focused on Glioma Diagnosis and Treatment (61 papers), Meningioma and schwannoma management (28 papers) and Brain Metastases and Treatment (27 papers). Clark C. Chen collaborates with scholars based in United States, China and Japan. Clark C. Chen's co-authors include Bob S. Carter, Johnny Akers, Ryan Kim, David Gonda, Fred H. Hochberg, Valya Ramakrishnan, Ying Mao, Wei Hua, Xandra O. Breakefield and Brian R. Hirshman and has published in prestigious journals such as Proceedings of the National Academy of Sciences, The Lancet and Journal of Biological Chemistry.

In The Last Decade

Clark C. Chen

119 papers receiving 5.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies

2013 1.1k citations Johnny Akers, David Gonda et al. Journal of Neuro-Oncology profile →
Coding and noncoding landscape of extracellular RNA released by human glioma stem cells

2017 394 citations Clark C. Chen, Fred H. Hochberg et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Clark C. Chen United States	36	3.2k	2.0k	1.5k	860	584	120	5.5k
Eiji Ikeda Japan	43	4.1k 1.3×	1.7k 0.9×	913 0.6×	1.2k 1.4×	435 0.7×	228	8.5k
Bernd Giebel Germany	41	5.5k 1.8×	2.6k 1.3×	1.7k 1.1×	513 0.6×	379 0.6×	146	7.9k
Ashok Srinivasan United States	35	2.2k 0.7×	1.5k 0.7×	439 0.3×	478 0.6×	454 0.8×	208	6.1k
William H. Yong United States	49	2.9k 0.9×	1.4k 0.7×	3.0k 2.1×	1.0k 1.2×	777 1.3×	179	8.7k
Andreas E. Kulozik Germany	54	6.4k 2.0×	1.0k 0.5×	2.0k 1.4×	995 1.2×	338 0.6×	230	10.2k
Nada Jabado Canada	48	3.0k 1.0×	881 0.4×	2.1k 1.4×	536 0.6×	778 1.3×	168	7.0k
Fausto J. Rodríguez United States	47	2.3k 0.7×	1.0k 0.5×	2.7k 1.9×	1.2k 1.4×	1.5k 2.5×	214	7.5k
Sydney M. Evans United States	43	1.6k 0.5×	2.5k 1.2×	583 0.4×	1.2k 1.4×	319 0.5×	135	5.6k
Francesco DiMeco Italy	41	3.5k 1.1×	1.7k 0.8×	3.1k 2.1×	541 0.6×	788 1.3×	167	8.5k
Arinobu Tojo Japan	45	3.1k 1.0×	854 0.4×	1.4k 1.0×	717 0.8×	578 1.0×	364	8.2k

Countries citing papers authored by Clark C. Chen

Since Specialization

Citations

This map shows the geographic impact of Clark C. Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Clark C. Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Clark C. Chen more than expected).

Fields of papers citing papers by Clark C. Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Clark C. Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Clark C. Chen. The network helps show where Clark C. Chen may publish in the future.

Co-authorship network of co-authors of Clark C. Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Clark C. Chen. A scholar is included among the top collaborators of Clark C. Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Clark C. Chen. Clark C. Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Coté, David J., Keiko M. Kang, Robert G. Briggs, et al.. (2025). Treatment practices and survival outcomes for IDH-wildtype glioblastoma patients according to MGMT promoter methylation status: insights from the U.S. National Cancer Database. Journal of Neuro-Oncology. 172(3). 655–665. 5 indexed citations

Hou, Jay, et al.. (2024). Cell migration simulator-based biomarkers for glioblastoma. Neuro-Oncology Advances. 6(1). vdae184–vdae184. 1 indexed citations

Chen, Clark C., et al.. (2024). Role of Extracellular vesicle microRNAs and RNA binding proteins on glioblastoma dynamics and therapeutics development. SHILAP Revista de lepidopterología. 4. 100049–100049. 8 indexed citations

Dhawan, Sanjay, Andrew S. Venteicher, William E. Butler, Bob S. Carter, & Clark C. Chen. (2021). Clinical outcomes as a function of the number of samples taken during stereotactic needle biopsies: a meta-analysis. Journal of Neuro-Oncology. 154(1). 1–11. 10 indexed citations

Zhang, Jinsen, et al.. (2020). Survival Association and Cell Cycle Effects of B7H3 in Neuroblastoma. Journal of Korean Neurosurgical Society. 63(6). 707–716. 16 indexed citations

Yu, Xiaoting, Lili Sun, Yanwen Zheng, et al.. (2020). GBP2 enhances glioblastoma invasion through Stat3/fibronectin pathway. Oncogene. 39(27). 5042–5055. 63 indexed citations

Olin, Michael R., Christopher A. Pennell, Aaron L. Sarver, et al.. (2019). Treatment Combining CD200 Immune Checkpoint Inhibitor and Tumor-Lysate Vaccination after Surgery for Pet Dogs with High-Grade Glioma. Cancers. 11(2). 137–137. 31 indexed citations

Bártek, Jiří, Ali Alattar, Sanjay Dhawan, et al.. (2019). Receipt of brachytherapy is an independent predictor of survival in glioblastoma in the Surveillance, Epidemiology, and End Results database. Journal of Neuro-Oncology. 145(1). 75–83. 17 indexed citations

Santiago-Dieppa, David R., et al.. (2018). Extracellular Vesicles as a Platform for Glioma Therapeutic Development. Progress in neurological surgery. 32. 172–179. 2 indexed citations

10.

Steed, Tyler, Jeffrey M. Treiber, Michael G. Brandel, et al.. (2018). Quantification of glioblastoma mass effect by lateral ventricle displacement. Scientific Reports. 8(1). 2827–2827. 20 indexed citations

11.

Ali, Mir Amaan, Brian R. Hirshman, Bayard Wilson, et al.. (2017). Survival Patterns of 5750 Stereotactic Radiosurgery–Treated Patients with Brain Metastasis as a Function of the Number of Lesions. World Neurosurgery. 107. 944–951.e1. 31 indexed citations

12.

Kalinina, Juliya, Jun Young Ahn, Narra S. Devi, et al.. (2016). Selective Detection of the D-enantiomer of 2-Hydroxyglutarate in the CSF of Glioma Patients with Mutated Isocitrate Dehydrogenase. Clinical Cancer Research. 22(24). 6256–6265. 52 indexed citations

13.

Yao, Yu, Hongxing Ye, Zengxin Qi, et al.. (2016). B7-H4(B7x)–Mediated Cross-talk between Glioma-Initiating Cells and Macrophages via the IL6/JAK/STAT3 Pathway Lead to Poor Prognosis in Glioma Patients. Clinical Cancer Research. 22(11). 2778–2790. 148 indexed citations

14.

Goetsch, Steven J., et al.. (2016). Stereotactic Radiosurgery Treatment of Trigeminal Neuralgia: Clinical Outcomes and Prognostic Factors. World Neurosurgery. 90. 604–612.e11. 23 indexed citations

15.

Chen, Clark C., Bob S. Carter, Renzhi Wang, et al.. (2016). Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Preoperative Imaging Assessment of Patients With Suspected Nonfunctioning Pituitary Adenomas. Neurosurgery. 79(4). E524–E526. 18 indexed citations

16.

McCabe, Nuala, Steven M. Walker, David Gonda, et al.. (2015). Mechanistic Rationale to Target PTEN-Deficient Tumor Cells with Inhibitors of the DNA Damage Response Kinase ATM. Cancer Research. 75(11). 2159–2165. 64 indexed citations

17.

Patel, Kunal, Yong Yao, Renzhi Wang, Bob S. Carter, & Clark C. Chen. (2015). Intraoperative magnetic resonance imaging assessment of non-functioning pituitary adenomas during transsphenoidal surgery. Pituitary. 19(2). 222–231. 21 indexed citations

18.

Moskwa, Patryk, Pascal O. Zinn, Young Eun Choi, et al.. (2014). A Functional Screen Identifies miRs That Induce Radioresistance in Glioblastomas. Molecular Cancer Research. 12(12). 1767–1778. 24 indexed citations

19.

McDuff, Susan G. R., Joshua D. Lawson, Parag Sanghvi, et al.. (2013). Neurocognitive assessment following whole brain radiation therapy and radiosurgery for patients with cerebral metastases: Table 1. Journal of Neurology Neurosurgery & Psychiatry. 84(12). 1384–1391. 87 indexed citations

20.

Gonda, David, Johnny Akers, Ryan Kim, et al.. (2012). Neuro-oncologic Applications of Exosomes, Microvesicles, and Other Nano-Sized Extracellular Particles. Neurosurgery. 72(4). 501–510. 33 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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