Christopher S. Hackett

3.5k total citations · 1 hit paper
25 papers, 2.3k citations indexed

About

Christopher S. Hackett is a scholar working on Molecular Biology, Neurology and Oncology. According to data from OpenAlex, Christopher S. Hackett has authored 25 papers receiving a total of 2.3k indexed citations (citations by other indexed papers that have themselves been cited), including 9 papers in Molecular Biology, 5 papers in Neurology and 5 papers in Oncology. Recurrent topics in Christopher S. Hackett's work include CAR-T cell therapy research (5 papers), Neuroblastoma Research and Treatments (5 papers) and Neonatal Health and Biochemistry (4 papers). Christopher S. Hackett is often cited by papers focused on CAR-T cell therapy research (5 papers), Neuroblastoma Research and Treatments (5 papers) and Neonatal Health and Biochemistry (4 papers). Christopher S. Hackett collaborates with scholars based in United States, United Kingdom and Canada. Christopher S. Hackett's co-authors include Sarwish Rafiq, Renier J. Brentjens, William A. Weiss, Philipp Strittmatter, Juris Ozols, Qi-Wen Fan, Zachary A. Knight, Theodore Nicolaides, Kevan M. Shokat and Christine Cheng and has published in prestigious journals such as Nucleic Acids Research, Journal of Biological Chemistry and Genes & Development.

In The Last Decade

Christopher S. Hackett

25 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Engineering strategies to overcome the current roadblocks in CAR T cell therapy

2019 1.0k citations Sarwish Rafiq, Christopher S. Hackett et al. Nature Reviews Clinical Oncology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Christopher S. Hackett United States	18	1.1k	1.1k	504	375	339	25	2.3k
László Perlaky United States	28	1.5k 1.4×	731 0.7×	307 0.6×	335 0.9×	151 0.4×	61	2.5k
Claudia Kowolik United States	26	1.6k 1.4×	1.3k 1.2×	739 1.5×	297 0.8×	201 0.6×	43	2.9k
Ren-Yuan Bai United States	20	917 0.8×	593 0.5×	206 0.4×	154 0.4×	169 0.5×	25	1.9k
Michael Mowat Canada	26	1.5k 1.3×	1.1k 1.0×	172 0.3×	287 0.8×	113 0.3×	51	2.3k
Hongmei Shen United States	23	1.5k 1.4×	854 0.8×	955 1.9×	208 0.6×	99 0.3×	48	3.1k
Frédéric Lopez France	25	1.3k 1.1×	471 0.4×	603 1.2×	138 0.4×	82 0.2×	46	2.6k
Jian Qiao United States	27	1.1k 1.0×	1.6k 1.4×	1.5k 2.9×	868 2.3×	278 0.8×	52	3.2k
Alex D. Waldman United States	7	955 0.9×	1.6k 1.4×	1.5k 3.0×	174 0.5×	480 1.4×	14	3.0k
Tori N. Yamamoto United States	17	875 0.8×	1.4k 1.3×	1.2k 2.5×	308 0.8×	365 1.1×	21	2.5k
Dieter Zopf Germany	25	1.6k 1.4×	1.1k 1.0×	233 0.5×	491 1.3×	80 0.2×	42	3.1k

Countries citing papers authored by Christopher S. Hackett

Since Specialization

Citations

This map shows the geographic impact of Christopher S. Hackett's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher S. Hackett with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher S. Hackett more than expected).

Fields of papers citing papers by Christopher S. Hackett

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher S. Hackett. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher S. Hackett. The network helps show where Christopher S. Hackett may publish in the future.

Co-authorship network of co-authors of Christopher S. Hackett

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher S. Hackett. A scholar is included among the top collaborators of Christopher S. Hackett based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher S. Hackett. Christopher S. Hackett is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Cohen, Tal, Paul Zumbo, Michael V. Gormally, et al.. (2025). Enhancing the Persistence and Anti-Tumor Efficacy of CAR-T and CAR-NK Cells through Genetic Disruption of Death Receptors. Transplantation and Cellular Therapy. 31(2). S1–S1. 1 indexed citations

Cohen, Tal, Paul Zumbo, Michael V. Gormally, et al.. (2024). Abstract 40: Persistence but not antitumor efficacy of CAR-engineered lymphocytes is governed by a FAS/FAS ligand auto-regulatory circuit. Cancer Research. 84(6_Supplement). 40–40. 1 indexed citations

Hackett, Christopher S., Daniel Hirschhorn, Alessandra Piersigilli, et al.. (2024). TYRP1 directed CAR T cells control tumor progression in preclinical melanoma models. SHILAP Revista de lepidopterología. 32(3). 200862–200862. 2 indexed citations

Hackett, Christopher S., et al.. (2022). Multipurposing CARs: Same engine, different vehicles. Molecular Therapy. 30(4). 1381–1395. 15 indexed citations

Rafiq, Sarwish, Christopher S. Hackett, & Renier J. Brentjens. (2019). Engineering strategies to overcome the current roadblocks in CAR T cell therapy. Nature Reviews Clinical Oncology. 17(3). 147–167. 1030 indexed citations breakdown →

Chen, Justin, Christopher S. Hackett, Shile Zhang, et al.. (2015). The Genetics of Splicing in Neuroblastoma. Cancer Discovery. 5(4). 380–395. 13 indexed citations

Diede, Scott J., Zizhen Yao, Ashlee E. Tyler, et al.. (2013). Fundamental differences in promoter CpG island DNA hypermethylation between human cancer and genetically engineered mouse models of cancer. Epigenetics. 8(12). 1254–1260. 15 indexed citations

Swartling, Fredrik J., Anders I. Persson, Justin Chen, et al.. (2012). Distinct Neural Stem Cell Populations Give Rise to Disparate Brain Tumors in Response to N-MYC. Cancer Cell. 21(5). 601–613. 156 indexed citations

Huang, Xi, Adrian M. Dubuc, Rintaro Hashizume, et al.. (2012). Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes & Development. 26(16). 1780–1796. 67 indexed citations

10.

Chanthery, Yvan H., W. Clay Gustafson, Melissa Itsara, et al.. (2012). Paracrine Signaling Through MYCN Enhances Tumor-Vascular Interactions in Neuroblastoma. Science Translational Medicine. 4(115). 115ra3–115ra3. 63 indexed citations

11.

Collier, Lara S., David J. Adams, Christopher S. Hackett, et al.. (2009). Whole-Body Sleeping Beauty Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality. Cancer Research. 69(21). 8429–8437. 59 indexed citations

12.

Fan, Qi-Wen, Christine Cheng, Theodore Nicolaides, et al.. (2007). A Dual Phosphoinositide-3-Kinase α/mTOR Inhibitor Cooperates with Blockade of Epidermal Growth Factor Receptor in PTEN -Mutant Glioma. Cancer Research. 67(17). 7960–7965. 160 indexed citations

13.

Hackett, Christopher S., Aron M. Geurts, & Perry B. Hackett. (2007). Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy. Genome Biology. 8(Suppl 1). S12–S12. 43 indexed citations

14.

Cheng, Andy, Ngan Ching Cheng, Jette Ford, et al.. (2007). Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma. European Journal of Cancer. 43(9). 1467–1475. 29 indexed citations

15.

Weiss, William A., Michael J. Burns, Christopher S. Hackett, et al.. (2003). Genetic determinants of malignancy in a mouse model for oligodendroglioma.. PubMed. 63(7). 1589–95. 129 indexed citations

16.

Hackett, Christopher S., John Hodgson, Mark E. Law, et al.. (2003). Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors.. PubMed. 63(17). 5266–73. 90 indexed citations

17.

Treanor, John J., Robert F. Betts, Gale Smith, et al.. (1996). Evaluation of a Recombinant Hemagglutinin Expressed in Insect Cells as an Influenza Vaccine in Young and Elderly Adults. The Journal of Infectious Diseases. 173(6). 1467–1470. 64 indexed citations

18.

Powers, Douglas C., Gale Smith, E. L. Anderson, et al.. (1995). Influenza A Virus Vaccines Containing Purified Recombinant H3 Hemagglutinin Are Well Tolerated and Induce Protective Immune Responses in Healthy Adults. The Journal of Infectious Diseases. 171(6). 1595–1599. 91 indexed citations

19.

Hackett, Christopher S., William B. Novoa, Charlotte R. Kensil, & Philipp Strittmatter. (1988). NADH binding to cytochrome b5 reductase blocks the acetylation of lysine 110.. Journal of Biological Chemistry. 263(16). 7539–7543. 18 indexed citations

20.

Strittmatter, Philipp, Mark A. Thiede, Christopher S. Hackett, & Juris Ozols. (1988). Bacterial synthesis of active rat stearyl-CoA desaturase lacking the 26-residue amino-terminal amino acid sequence.. Journal of Biological Chemistry. 263(5). 2532–2535. 37 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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