Christopher A. Vakulskas

5.4k total citations · 2 hit papers
38 papers, 3.2k citations indexed

About

Christopher A. Vakulskas is a scholar working on Molecular Biology, Genetics and Endocrinology. According to data from OpenAlex, Christopher A. Vakulskas has authored 38 papers receiving a total of 3.2k indexed citations (citations by other indexed papers that have themselves been cited), including 35 papers in Molecular Biology, 17 papers in Genetics and 9 papers in Endocrinology. Recurrent topics in Christopher A. Vakulskas's work include CRISPR and Genetic Engineering (16 papers), Bacterial Genetics and Biotechnology (14 papers) and RNA and protein synthesis mechanisms (10 papers). Christopher A. Vakulskas is often cited by papers focused on CRISPR and Genetic Engineering (16 papers), Bacterial Genetics and Biotechnology (14 papers) and RNA and protein synthesis mechanisms (10 papers). Christopher A. Vakulskas collaborates with scholars based in United States, Japan and Mexico. Christopher A. Vakulskas's co-authors include Tony Romeo, Paul Babitzke, Mark A. Behlke, Anastasia H. Potts, Michael A. Collingwood, Brian M. M. Ahmer, Timothy L. Yahr, Matthew H. Porteus, Daniel P. Dever and Helen Yakhnin and has published in prestigious journals such as Nature, Nucleic Acids Research and Nature Medicine.

In The Last Decade

Christopher A. Vakulskas

37 papers receiving 3.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Identification of preexisting adaptive immunity to Cas9 proteins in humans

2019 665 citations Carsten T. Charlesworth, Daniel P. Dever et al. Nature Medicine profile →
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells

2018 541 citations Christopher A. Vakulskas, Daniel P. Dever et al. Nature Medicine profile →

Peers

Countries citing papers authored by Christopher A. Vakulskas

Since Specialization

Citations

This map shows the geographic impact of Christopher A. Vakulskas's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher A. Vakulskas with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher A. Vakulskas more than expected).

Fields of papers citing papers by Christopher A. Vakulskas

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher A. Vakulskas. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher A. Vakulskas. The network helps show where Christopher A. Vakulskas may publish in the future.

Co-authorship network of co-authors of Christopher A. Vakulskas

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher A. Vakulskas. A scholar is included among the top collaborators of Christopher A. Vakulskas based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher A. Vakulskas. Christopher A. Vakulskas is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Reprogramming site-specific retrotransposon activity to new DNA sites 2025 ·Nature ·(unknown), Lukas Villiger, Justin Lim, Masahiro Hiraizumi, (unknown), (unknown), (unknown), Kaiyi Jiang, Alişan Kayabölen, Rohan N. Krajeski, Cian Schmitt-Ulms, (unknown), (unknown), (unknown), Christopher A. Vakulskas, Hiroshi Nishimasu, Omar O. Abudayyeh, Jonathan S. Gootenberg	8
2	Amplification-free detection of plant pathogens by improved CRISPR-Cas12a systems: a case study on phytoplasma 2025 ·Frontiers in Plant Science ·(unknown), Eric A. Newberry, Yazmín Rivera, Liyang Zhang, Christopher A. Vakulskas, Yiping Qi	1
3	Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells 2024 ·Nature Communications ·Ron Baik, M. Kyle Cromer, (unknown), Christopher A. Vakulskas, (unknown), Amanda M. Dudek, (unknown), Julia Klermund, (unknown), Toni Cathomen, Daniel P. Dever, Matthew H. Porteus	8
4	Propensity of Patient-Derived iPSCs for Retinal Differentiation: Implications for Autologous Cell Replacement 2023 ·Stem Cells Translational Medicine ·(unknown), Andrew P. Voigt, Michael A. Collingwood, (unknown), S. Scott Whitmore, Adam P. DeLuca, Erin R. Burnight, Kristin R. Anfinson, Christopher A. Vakulskas, (unknown), Heather T. Daggett, Jeaneen L. Andorf, Edwin M. Stone, Robert F. Mullins, Budd A. Tucker	12
5	Generation of the transgene-free canker-resistant Citrus sinensis using Cas12a/crRNA ribonucleoprotein in the T0 generation 2023 ·Nature Communications ·Hang Su, Yuanchun Wang, Jin Xu, Ahmad A. Omar, Jude W. Grosser, (unknown), Liyang Zhang, (unknown), Christopher A. Vakulskas, Nian Wang	53
6	Boosting genome editing efficiency in human cells and plants with novel LbCas12a variants 2023 ·Genome biology ·Liyang Zhang, Gen Li, Yingxiao Zhang, Yanhao Cheng, (unknown), (unknown), (unknown), H. Tomas Rube, (unknown), Gary D. Coleman, Christopher A. Vakulskas, Yiping Qi	30
7	Efficiency, Specificity and Temperature Sensitivity of Cas9 and Cas12a RNPs for DNA-free Genome Editing in Plants 2022 ·SHILAP Revista de lepidopterología ·Raviraj Banakar, Mollie S. Schubert, Gavin Kurgan, Krishan Mohan, (unknown), Michael A. Collingwood, Christopher A. Vakulskas, Kan Wang, Feng Zhang	22
8	Highly Efficient Genome Editing in Plant Protoplasts by Ribonucleoprotein Delivery of CRISPR-Cas12a Nucleases 2022 ·SHILAP Revista de lepidopterología ·Yingxiao Zhang, Yanhao Cheng, Hong Fang, (unknown), Liyang Zhang, Christopher A. Vakulskas, Randall P. Niedz, James N. Culver, Yiping Qi	36
9	Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes 2020 ·Nucleic Acids Research ·Liyang Zhang, H. Tomas Rube, Christopher A. Vakulskas, Mark A. Behlke, Harmen J. Bussemaker, Miles A. Pufall	31
10	Could a CRISPR Therapeutic Cure Sickle-Cell Disease? 2020 ·Genetic Engineering & Biotechnology News ·Christopher A. Vakulskas	1
11	Comparison of CRISPR-Cas9/Cas12a Ribonucleoprotein Complexes for Genome Editing Efficiency in the Rice Phytoene Desaturase (OsPDS) Gene 2020 ·Rice ·Raviraj Banakar, Mollie S. Schubert, Michael A. Collingwood, Christopher A. Vakulskas, Alan L. Eggenberger, Kan Wang	70
12	Identification of preexisting adaptive immunity to Cas9 proteins in humans breakdown → 2019 ·Nature Medicine ·Carsten T. Charlesworth, (unknown), Daniel P. Dever, Joab Camarena, Viktor T. Lemgart, M. Kyle Cromer, Christopher A. Vakulskas, Michael A. Collingwood, Liyang Zhang, Nicole M. Bode, Mark A. Behlke, Beruh Dejene, Brandon Cieniewicz, Rosa Romano, Benjamin J. Lesch, Natalia Gomez‐Ospina, Sruthi Mantri, Mara Pavel-Dinu, Kenneth I. Weinberg, Matthew H. Porteus	665
13	Evaluation and Reduction of CRISPR Off-Target Cleavage Events 2019 ·Nucleic Acid Therapeutics ·Christopher A. Vakulskas, Mark A. Behlke	85
14	A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells breakdown → 2018 ·Nature Medicine ·Christopher A. Vakulskas, Daniel P. Dever, Garrett R. Rettig, Rolf Turk, Ashley M. Jacobi, Michael A. Collingwood, Nicole M. Bode, Matthew McNeill, Shuqi Yan, Joab Camarena, Ciaran M. Lee, So Hyun Park, Volker Wiebking, Rasmus O. Bak, Natalia Gomez‐Ospina, Mara Pavel-Dinu, Wenchao Sun, Gang Bao, Matthew H. Porteus, Mark A. Behlke	541
15	Preclinical Development of HBB Gene Correction in Autologous Hematopoietic Stem and Progenitor Cells to Treat Severe Sickle Cell Disease 2017 ·Blood ·Daniel P. Dever, Joab Camarena, Ciaran M. Lee, Christopher A. Vakulskas, Mark A. Behlke, Gang Bao, Matthew H. Porteus	4
16	Antagonistic control of the turnover pathway for the global regulatory sRNA CsrB by the CsrA and CsrD proteins 2016 ·Nucleic Acids Research ·Christopher A. Vakulskas, (unknown), (unknown), (unknown), (unknown), Paul Babitzke, Kazushi Suzuki, Tony Romeo	46
17	Non-nucleotide Modification of Anti-miRNA Oligonucleotides 2016 ·Methods in molecular biology ·Kim A. Lennox, Christopher A. Vakulskas, Mark A. Behlke	15
18	Dual Posttranscriptional Regulation via a Cofactor-Responsive mRNA Leader 2012 ·Journal of Molecular Biology ·Laura Patterson-Fortin, Christopher A. Vakulskas, Helen Yakhnin, Paul Babitzke, Tony Romeo	53
19	Post‐transcriptional regulation on a global scale: form and function of Csr/Rsm systems 2012 ·Environmental Microbiology ·Tony Romeo, Christopher A. Vakulskas, Paul Babitzke	235
20	Translational Repression of NhaR, a Novel Pathway for Multi-Tier Regulation of Biofilm Circuitry by CsrA 2011 ·Journal of Bacteriology ·(unknown), Helen Yakhnin, Christopher A. Vakulskas, Adrianne N. Edwards, Paul Babitzke, Tony Romeo	52

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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