Christine Lambert‐van der Brempt

1.3k total citations
20 papers, 925 citations indexed

About

Christine Lambert‐van der Brempt is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, Christine Lambert‐van der Brempt has authored 20 papers receiving a total of 925 indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 6 papers in Organic Chemistry and 5 papers in Oncology. Recurrent topics in Christine Lambert‐van der Brempt's work include PI3K/AKT/mTOR signaling in cancer (7 papers), Chronic Lymphocytic Leukemia Research (4 papers) and Protein Kinase Regulation and GTPase Signaling (4 papers). Christine Lambert‐van der Brempt is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (7 papers), Chronic Lymphocytic Leukemia Research (4 papers) and Protein Kinase Regulation and GTPase Signaling (4 papers). Christine Lambert‐van der Brempt collaborates with scholars based in United Kingdom, France and Sweden. Christine Lambert‐van der Brempt's co-authors include Patrick A. Plé, Laurent Hennequin, Jon Curwen, Gerard Costello, Tim P. Green, Michael Fennell, J M Allen, Bernard Barlaam, Nicolas Warin and Annie Olivier and has published in prestigious journals such as Cancer Research, Journal of Medicinal Chemistry and Tetrahedron.

In The Last Decade

Christine Lambert‐van der Brempt

19 papers receiving 892 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Christine Lambert‐van der Brempt United Kingdom 11 520 331 243 86 81 20 925
John M. Hatcher United States 16 574 1.1× 252 0.8× 211 0.9× 87 1.0× 63 0.8× 33 967
Gerard Costello United Kingdom 12 526 1.0× 314 0.9× 243 1.0× 82 1.0× 84 1.0× 16 946
Peter Drueckes Switzerland 15 727 1.4× 173 0.5× 290 1.2× 146 1.7× 118 1.5× 24 1.2k
Bertrand Leblond France 17 665 1.3× 259 0.8× 142 0.6× 58 0.7× 121 1.5× 29 1.2k
Benedict‐Tilman Berger Germany 19 590 1.1× 207 0.6× 197 0.8× 49 0.6× 79 1.0× 50 904
Cesear Corona United States 15 627 1.2× 149 0.5× 296 1.2× 72 0.8× 86 1.1× 22 969
Patrick A. Plé United Kingdom 17 877 1.7× 572 1.7× 445 1.8× 169 2.0× 124 1.5× 30 1.5k
Danny Tam United States 14 449 0.9× 119 0.4× 144 0.6× 76 0.9× 58 0.7× 25 870
Tim P. Green United Kingdom 13 699 1.3× 178 0.5× 504 2.1× 159 1.8× 118 1.5× 14 1.2k
Melanie Wong United States 17 418 0.8× 160 0.5× 156 0.6× 35 0.4× 38 0.5× 23 830

Countries citing papers authored by Christine Lambert‐van der Brempt

Since Specialization
Citations

This map shows the geographic impact of Christine Lambert‐van der Brempt's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christine Lambert‐van der Brempt with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christine Lambert‐van der Brempt more than expected).

Fields of papers citing papers by Christine Lambert‐van der Brempt

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christine Lambert‐van der Brempt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christine Lambert‐van der Brempt. The network helps show where Christine Lambert‐van der Brempt may publish in the future.

Co-authorship network of co-authors of Christine Lambert‐van der Brempt

This figure shows the co-authorship network connecting the top 25 collaborators of Christine Lambert‐van der Brempt. A scholar is included among the top collaborators of Christine Lambert‐van der Brempt based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christine Lambert‐van der Brempt. Christine Lambert‐van der Brempt is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Barlaam, Bernard, Sabina Cosulich, Martina Fitzek, et al.. (2017). Discovery of a novel aminopyrazine series as selective PI3Kα inhibitors. Bioorganic & Medicinal Chemistry Letters. 27(13). 3030–3035. 5 indexed citations
2.
Barlaam, Bernard, Sabina Cosulich, Sébastien L. Degorce, et al.. (2017). Discovery of a series of 8-(1-phenylpyrrolidin-2-yl)-6-carboxamide-2-morpholino-4H-chromen-4-one as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours. Bioorganic & Medicinal Chemistry Letters. 27(9). 1949–1954. 3 indexed citations
3.
Barlaam, Bernard, Sabina Cosulich, Sébastien L. Degorce, et al.. (2016). Discovery of a series of 8-(2,3-dihydro-1,4-benzoxazin-4-ylmethyl)-2-morpholino-4-oxo-chromene-6-carboxamides as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours. Bioorganic & Medicinal Chemistry Letters. 26(9). 2318–2323. 6 indexed citations
4.
Barlaam, Bernard, Sabina Cosulich, Martina Fitzek, et al.. (2015). Design of selective PI3Kα inhibitors starting from a promiscuous pan kinase scaffold. Bioorganic & Medicinal Chemistry Letters. 25(13). 2679–2685. 7 indexed citations
5.
Barlaam, Bernard, Sabina Cosulich, Bénédicte Delouvrié, et al.. (2015). Abstract 2830: Discovery of AZD8835, a potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment of PIK3CA-dependent cancers. Cancer Research. 75(15_Supplement). 2830–2830.
6.
Barlaam, Bernard, Sabina Cosulich, Sébastien L. Degorce, et al.. (2014). Discovery of 9-(1-anilinoethyl)-2-morpholino-4-oxo-pyrido[1,2-a]pyrimidine-7-carboxamides as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours. Bioorganic & Medicinal Chemistry Letters. 24(16). 3928–3935. 17 indexed citations
7.
Barlaam, Bernard, Sabina Cosulich, Sébastien L. Degorce, et al.. (2014). Discovery of (R)-8-(1-(3,5-Difluorophenylamino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide (AZD8186): A Potent and Selective Inhibitor of PI3Kβ and PI3Kδ for the Treatment of PTEN-Deficient Cancers. Journal of Medicinal Chemistry. 58(2). 943–962. 66 indexed citations
8.
Barlaam, Bernard, Judith Anderton, Peter Ballard, et al.. (2013). Discovery of AZD8931, an Equipotent, Reversible Inhibitor of Signaling by EGFR, HER2, and HER3 Receptors. ACS Medicinal Chemistry Letters. 4(8). 742–746. 31 indexed citations
9.
Plé, Patrick A., Frédéric Jung, Sue Ashton, et al.. (2012). Discovery of new quinoline ether inhibitors with high affinity and selectivity for PDGFR tyrosine kinases. Bioorganic & Medicinal Chemistry Letters. 22(9). 3050–3055. 7 indexed citations
10.
Degorce, Sébastien L., Bénédicte Delouvrié, Paul R. J. Davey, et al.. (2012). Facile, diversity-orientated one-pot synthesis of ethyl 1,5-disubstituted-1H-1,2,4-triazole-3-carboxylates. Tetrahedron Letters. 53(45). 6078–6082. 7 indexed citations
11.
Barlaam, Bernard, Richard Ducray, Christine Lambert‐van der Brempt, et al.. (2011). Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series. Bioorganic & Medicinal Chemistry Letters. 21(8). 2207–2211. 26 indexed citations
12.
Harris, Craig S., et al.. (2011). Efficient Three-Step One-Pot Synthesis of a Novel 2,3,5-Substituted Pyrazine Library. ACS Combinatorial Science. 13(5). 449–452. 10 indexed citations
13.
Bardelle, Catherine, Bernard Barlaam, Nigel Brooks, et al.. (2010). Inhibitors of the tyrosine kinase EphB4. Part 3: Identification of non-benzodioxole-based kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 20(21). 6242–6245. 30 indexed citations
14.
Andrews, David, et al.. (2009). Fischer synthesis of isomeric thienopyrrole LHRH antagonists. Tetrahedron. 65(29-30). 5805–5816. 8 indexed citations
15.
16.
Brempt, Christine Lambert‐van der. (2004). La modélisation moléculaire, une aide à la conception de nouveaux médicaments. 10(4). 244–251. 1 indexed citations
17.
Plé, Patrick A., Tim P. Green, Laurent Hennequin, et al.. (2004). Discovery of a New Class of Anilinoquinazoline Inhibitors with High Affinity and Specificity for the Tyrosine Kinase Domain of c-Src. Journal of Medicinal Chemistry. 47(4). 871–887. 139 indexed citations
18.
Barlaam, Bernard, et al.. (1999). New α-Substituted Succinate-Based Hydroxamic Acids as TNFα Convertase Inhibitors. Journal of Medicinal Chemistry. 42(23). 4890–4908. 73 indexed citations
19.
Hennequin, Laurent, Andrew P. Thomas, Craig Johnstone, et al.. (1999). Design and Structure−Activity Relationship of a New Class of Potent VEGF Receptor Tyrosine Kinase Inhibitors. Journal of Medicinal Chemistry. 42(26). 5369–5389. 195 indexed citations
20.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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