Chaim O. Jacob

15.1k total citations · 5 hit papers
96 papers, 7.8k citations indexed

About

Chaim O. Jacob is a scholar working on Immunology, Rheumatology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Chaim O. Jacob has authored 96 papers receiving a total of 7.8k indexed citations (citations by other indexed papers that have themselves been cited), including 53 papers in Immunology, 42 papers in Rheumatology and 22 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Chaim O. Jacob's work include Systemic Lupus Erythematosus Research (39 papers), T-cell and B-cell Immunology (27 papers) and Monoclonal and Polyclonal Antibodies Research (22 papers). Chaim O. Jacob is often cited by papers focused on Systemic Lupus Erythematosus Research (39 papers), T-cell and B-cell Immunology (27 papers) and Monoclonal and Polyclonal Antibodies Research (22 papers). Chaim O. Jacob collaborates with scholars based in United States, Israel and United Kingdom. Chaim O. Jacob's co-authors include Hugh O. McDevitt, Gideon Strassmann, M Fong, Zdenka Fronek, Carl D. Langefeld, Marta E. Alarcón‐Riquelme, Betty P. Tsao, Lindsey A. Criswell, J S Kenney and Robert P. Kimberly and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Chaim O. Jacob

95 papers receiving 7.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

2008 950 citations Marta E. Alarcón‐Riquelme, Lindsey A. Criswell et al. profile →
A Molecular Basis for MHC Class II—Associated Autoimmunity

1988 606 citations Nelson J. Chao, Chaim O. Jacob et al. profile →
Evidence for the involvement of interleukin 6 in experimental cancer cachexia.

1992 541 citations Gideon Strassmann, M Fong et al. Journal of Clinical Investigation profile →
Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus.

1990 537 citations Chaim O. Jacob, Hugh O. McDevitt et al. profile →
Tumour necrosis factor-α in murine autoimmune 'lupus' nephritis

1988 491 citations Chaim O. Jacob, Hugh O. McDevitt Nature profile →

Peers

Countries citing papers authored by Chaim O. Jacob

Since Specialization

Citations

This map shows the geographic impact of Chaim O. Jacob's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Chaim O. Jacob with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Chaim O. Jacob more than expected).

Fields of papers citing papers by Chaim O. Jacob

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Chaim O. Jacob. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Chaim O. Jacob. The network helps show where Chaim O. Jacob may publish in the future.

Co-authorship network of co-authors of Chaim O. Jacob

This figure shows the co-authorship network connecting the top 25 collaborators of Chaim O. Jacob. A scholar is included among the top collaborators of Chaim O. Jacob based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Chaim O. Jacob. Chaim O. Jacob is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Lupus-prone NZM2328 mice exhibit enhanced UV-induced myeloid cell recruitment and activation in a type I interferon dependent manner 2024 ·Journal of Autoimmunity ·(unknown), (unknown), Céline C. Berthier, Lam C. Tsoi, (unknown), Sonya Wolf, Hong Shi, Shannon Loftus, (unknown), (unknown), Matthias Kretzler, Chaim O. Jacob, Jóhann E. Guðjónsson, J. Michelle Kahlenberg	5
2	Lupus-associated NCF2 variant p.R395W in the NADPH oxidase 2 complex results in a reduced production of reactive oxygen species by myeloid cells 2023 ·Zhimin Song, Dae‐Goon Yoo, Rachel A. Idol, Emilia Alina Barbu, Chaim O. Jacob, Mary C. Dinauer	1
3	Context-dependent induction of autoimmunity by TNF signaling deficiency 2022 ·JCI Insight ·Tâm D. Quách, Weiqing Huang, Ranjit Kumar Sahu, (unknown), (unknown), (unknown), Tung Ming Leung, Susan Malkiel, (unknown), Stefania Gallucci, Çağla Tükel, Chaim O. Jacob, Martin Lesser, Yong-Rui Zou, Anne Davidson	3
4	Haploinsufficiency of NADPH Oxidase Subunit Neutrophil Cytosolic Factor 2 Is Sufficient to Accelerate Full‐Blown Lupus in NZM 2328 Mice 2017 ·Arthritis & Rheumatology ·Chaim O. Jacob, Ning Yu, Dae‐Goon Yoo, (unknown), Emilia Alina Barbu, Mariana J. Kaplan, Monica Purmalek, Jeanette T. Pingel, Rachel A. Idol, Mary C. Dinauer	46
5	IgG1 protects against renal disease in a mouse model of cryoglobulinaemia 2014 ·Nature ·Richard T. Strait, (unknown), Ashley M. Mahler, (unknown), Chaim O. Jacob, Jörg Köhl, Marc Ehlers, Keith Stringer, Shiva Kumar Shanmukhappa, David P. Witte, (unknown), Marat Khodoun, Andrew B. Herr, Fred D. Finkelman	54
6	GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region 2014 ·Genes and Immunity ·Don Armstrong, Raphael Zidovetzki, Marta E. Alarcón‐Riquelme, Betty P. Tsao, Lindsey A. Criswell, Robert P. Kimberly, J B Harley, Kathy L. Sivils, Tim J. Vyse, Patrick M. Gaffney, Carl D. Langefeld, Chaim O. Jacob	88
7	Deficiency of Type I IFN Receptor in Lupus-Prone New Zealand Mixed 2328 Mice Decreases Dendritic Cell Numbers and Activation and Protects from Disease 2009 ·The Journal of Immunology ·Hemant Agrawal, Noam Jacob, Esther Carreras, Sandra Bajaña, Chaim Putterman, Seán Turner, Barbara R. Neas, Alexis Mathian, Michael N. Koss, William Stohl, Susan Kovats, Chaim O. Jacob	101
8	Accelerated Pathological and Clinical Nephritis in Systemic Lupus Erythematosus-Prone New Zealand Mixed 2328 Mice Doubly Deficient in TNF Receptor 1 and TNF Receptor 2 via a Th17-Associated Pathway 2009 ·The Journal of Immunology ·Noam Jacob, Haitao Yang, Luminita Pricop, Yi Liu, Xiaoni Gao, Song Guo Zheng, Juhua Wang, (unknown), Chaim Putterman, Michael N. Koss, William Stohl, Chaim O. Jacob	81
9	Admixture in Hispanic Americans: its impact on ITGAM association and implications for admixture mapping in SLE 2009 ·Genes and Immunity ·Julio E. Molineros, Xana Kim-Howard, Harshal Deshmukh, Chaim O. Jacob, John B. Harley, Swapan K. Nath	19
10	Evaluation of C1q genomic region in minority racial groups of lupus 2009 ·Genes and Immunity ·Bahram Namjou, Courtney Gray‐McGuire, Andrea L. Sestak, Gary S. Gilkeson, Chaim O. Jacob, Joan T. Merrill, (unknown), Edward K. Wakeland, Q-Z Li, Carl D. Langefeld, Jasmin Divers, Julie T. Ziegler, K L Moser, Jennifer A. Kelly, Kenneth M. Kaufman, J B Harley	31
11	Function2Gene: A gene selection tool to increase the power of genetic association studies by utilizing public databases and expert knowledge 2008 ·BMC Bioinformatics ·Don Armstrong, Chaim O. Jacob, Raphael Zidovetzki	2
12	Differential Contribution of IL-4 and STAT6 vs STAT4 to the Development of Lupus Nephritis 2003 ·The Journal of Immunology ·Ram Raj Singh, Vijay Saxena, (unknown), Lily Li, Fred D. Finkelman, David P. Witte, Chaim O. Jacob	112
13	Pivotal Role of Stat4 and Stat6 in the Pathogenesis of the Lupus-Like Disease in the New Zealand Mixed 2328 Mice 2003 ·The Journal of Immunology ·Chaim O. Jacob, (unknown), Lily Li, (unknown), (unknown), (unknown), Minoru Satoh, Michael N. Koss	87
14	In vivo staphylococcal superantigen-driven polyclonal Ig responses in mice: dependence upon CD4+ cells and human MHC class II 2001 ·International Immunology ·William Stohl, Dong Xu, (unknown), Kyung Sik Kim, Lily Li, Julie A. Hanson, S. A. Stohlman, Chella S. David, Chaim O. Jacob	15
15	Genome-Wide Screen for Systemic Lupus Erythematosus Susceptibility Genes in Multiplex Families 1999 ·Human Molecular Genetics ·(unknown), Francisco P. Quismorio, Lin Li, Oh Joon Kwon, John L. Morrison, Daniel J. Wallace, C. Michael Neuwelt, Chaim Brautbar, W. James Gauderman, Chaim O. Jacob	249
16	IL-4 and IL-13 Modulate IL-10 Release in Endotoxin-Stimulated Murine Peritoneal Mononuclear Phagocytes 1996 ·Cellular Immunology ·Taku Kambayashi, Chaim O. Jacob, Gideon Strassmann	63
17	Mechanisms of paraneoplastic syndromes of colon-26: Involvement of interleukin 6 in hypercalcemia 1993 ·Cytokine ·Gideon Strassmann, Chaim O. Jacob, Miranda Fong, Donald R. Bertolini	21
18	Evidence for the involvement of interleukin 6 in experimental cancer cachexia. breakdown → 1992 ·Journal of Clinical Investigation ·Gideon Strassmann, M Fong, J S Kenney, Chaim O. Jacob	541
19	Molecular characterization of MHC class II antigens (? 1 domain) in the BB diabetes-prone and -resistant rat 1989 ·Immunogenetics ·Nelson J. Chao, Luika Timmerman, Hugh O. McDevitt, Chaim O. Jacob	36
20	In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon. 1987 ·The Journal of Experimental Medicine ·Chaim O. Jacob, Peter H. van der Meide, Hugh O. McDevitt	328

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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